Significantly reduce off-target editing events when using CRISPR-Cas9 without loss of editing efficiency in a broad range of cell types including primary immune and stem cells.
• Over 90% reduction in off-target cleavage events in primary T cells
• Maintain high editing efficiency compared to CTS TrueCut Cas9 (our wild-type protein)
• 2-fold improved knock-in efficiency when used with CTS Xenon Genome Editing Buffer kit
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