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Unstoppable Confidence in GC-MS and GC-MS/MS Analysis - Enabling you to Stay Ahead
To confidently stay ahead, your GC-MS/MS system must deliver ultimate performance while consistently producing trusted quantitative results. That’s the reason for the Thermo Scientific ISQ 7610 Single Quadrupole GC-MS and the Thermo Scientific TSQ 9610 Triple Quadrupole GC-MS/MS Systems. User-centric Thermo Scientific NeverVent technology, extended-life detector, and intelligent software eliminate unnecessary downtime to maximize your sample throughput and return on investment (ROI).
- Increase instrument uptime with NeverVent technology
- Maximizing sample throughput with the new extended lifetime and extended dynamic range detector
- Providing a rapid ROI with innovative software solutions including instrument health, compliant SmartTune and ready to implement methods
Stay ahead with unstoppable confidence in GC-MS analysis
As the challenges for analytical testing expand with changing regulations, additional compounds to monitor and increased competition It is important to stay ahead. The Thermo Scientific ISQ 7610 GC single Quadrupole Mass Spectrometer offers unstoppable confidence to exceed your analytical goals.
Unstoppable confidence in quantitative performance
Click image to enlarge
Your GC-MS systems must provide the sensitivity, speed, and reproducibility required to carry out regulated methods consistently and efficiently, day after day. The ISQ 7610 Single Quadrupole GC-MS System delivers sensitive and reproducible analysis for a broad range of quantitative workflows.
Choose either the rugged Thermo Scientific ExtractaBrite ion source technology or the ultra-sensitive, ultra-robust Thermo Scientific Advanced Electron Ionization (AEI) source. Available in a dedicated system configuration, the AEI source allows you to drive down instrument detection limits and reduce time-consuming sample concentration steps.
Unstoppable instrument uptime for full-time productivity
Unplanned or planned downtime can result in poor asset utilization and reduced sample throughput. The ISQ 7610 Single Quadrupole GC-MS System features user-centric innovations that reduce downtime for routine maintenance, while instrument health monitoring assists you in determining when maintenance is needed to avoid unnecessary downtime. As a result, you maximize instrument utilization, sample throughput, and ultimately ROI.
Using NeverVent technology available with the ExtractaBrite source allows the use of the Vacuum Probe Interlock (VPI) and V-Lock source plug. This enables planned maintenance, such as changing columns and ion source cleaning, to be performed without venting the mass spectrometer, increasing uptime. The VPI can also be used to avoid venting when changing between electron ionization (EI) and chemical ionization (CI) modes.
Unstoppable return on investment
Rapid instrument deployment reduces time to results and revenue generation. That’s why the ISQ 7610 Single Quadrupole GC-MS System includes a comprehensive set of automated tools to provide users with a seamless experience when transitioning from other platforms, developing methods, and analyzing samples. This built-in intelligence reduces operator training needs and time to full productivity for rapid ROI.
Target analysis
Method development
Routine analysis
AutoSIM
AutoSIM allows you to acquire full-scan data, enter or import from external file (csv, Excel, LIMS database) your list of target analytes, and perform selection of the SIM ions from the FS data in a guided, automated fashion. A real time saver and productivity booster.
Timed-SIM method
Timed Acquisition (t-SIM) helps optimize the dwell times in SIM quantitation methods with large number of analytes, especially in case of co-elution, assuring the maximum sensitivity. However, a manual set up of t-SIM can be tedious. This is why AutoSIM is complementary to t-SIM, for a fully automated workflow.
Retention Time Alignment (RTA)
The new RTA tool uses Void Time and Retention Time of a reference substance to provide new carrier flow and pressure settings or new columns dimension settings to realign retention times of all the peaks of the chromatograms. This means that during a column change or trim, you can quickly re-align the retention times and return to collecting results.
Untargeted screening
Method development
Routine analysis
Full-scan acquisition
For untargeted analysis, leverage the easier and quick set up of a full-scan acquisition method, maintaining the analytical information of the entire mass range.
Mass spectral deconvolution
Unravel the heaviest co-elution of the TIC chromatogram by reconstructing clean mass spectra for heavy co-eluted compounds, ready for reliable library searching and ID confirmation.
Mass spectral deconvolution (continued)
SmartTune
SmartTune is the simplified tuning tool for Thermo Scientific ISQ and TSQ instruments. This intuitive tool removes tuning complexity and ensures your system is performing at the level you require, ahead of running your samples. A simple guided interface efficiently checks and tunes the system, and intelligently eliminates any unnecessary steps in the process, resulting in faster tuning operations. If a problem is detected, SmartTune advises you on recommended corrective action. In addition, SmartTune allows user customizable targets to facilitate consistency in performance between analytical sequences.
Unstoppable confidence in your future
Click image to enlarge
To ensure you are ready for any analytical challenge, the ISQ 7610 Single Quadrupole GC-MS System is fully upgradable from entry-level to advanced configurations. Now you can be confident that your laboratory can adapt to new challenges using the same investments in GC-MS technology. Select from five levels of performance with field-upgradeable options. All configurations are based on the user-centric ISQ single quadrupole design with easy-to-use tools such as SmartTune, AutoSIM, and t-SIM that facilitate adoption and method setup.
The right choice for any workflow
The ISQ 7610 Single Quadrupole GC-MS System can be implemented seamlessly into any laboratory workflow to increase efficiency. Navigate your most difficult analytical challenges and easily obtain results with automated workflows and simplified operation.
The Thermo Scientific TRACE 1600 Series GC can be coupled with sampling solutions like Purge and Trap, Thermal Desorption, and pyrolysis to analyze a breadth of environmental samples. These sampling solutions are fully controlled in Thermo Scientific Chromeleon Chromatography Data System (CDS), facilitating compliance and ensuring confidence in results. For U.S. EPA-based environmental applications, the Environmental Analysis Extension Pack available in our AppsLab method library provides a comprehensive set of GC-MS e-workflows and reporting templates.
- Fixed Calibration, Check Standards, QC Samples, Unknowns
- Tune Check, Calibration Curve, QC Samples
- Fixed Calibration, Check Standards, Injections for computing Minimum Detection Level (MDL)
- Fixed Calibration, Check Standards, Injections for performing method validation
Stay ahead with Unstoppable confidence in GC-MS/MS analysis
When sample throughput is the key to your your laboratory staying ahead, the Thermo Scientific TSQ 9610 GC Triple Quadrupole mass spectrometer offers unstoppable confidence to exceed your analytical goals.
Unstoppable confidence in quantitative performance
Click image to enlarge
Confidence in quantitation is assured with best-in-class sensitivity, speed, and reproducibility, delivered consistently, day after day. The TSQ 9610 Triple Quadrupole GC-MS/MS System provides high-sensitivity analysis with design innovations such as the ExtractaBrite ion source, highest sensitivity AEI source, and EvoCell.
Choose either the rugged Thermo Scientific ExtractaBrite ion source or the ultra-sensitive, ultra-robust ThermoScientific Advanced Electron Ionization (AEI) source. Both ionization sources can be equipped with NeverVent technology and produce consistent low level results
Unstoppable confidence in uptime for full-time productivity
Click image to enlarge
Unplanned or planned downtime can result in poor asset utilization and reduced sample throughput. TSQ 9610 Triple Quadrupole GC-MS/MS System features innovations that reduce downtime for routine maintenance, while instrument health monitoring assists you in determining when maintenance is needed to avoid unnecessary downtime. As a result, you maximize instrument utilization, sample throughput, and ultimately ROI.
Using NeverVent technology with the Vacuum Probe Interlock (VPI) and V-Lock source plug, planned maintenance such as changing column and ion source cleaning can be performed without venting the mass spectrometer, increasing uptime. NeverVent technology is available on both the Thermo Scientific ExtractaBrite and the Thermo Scientific Advanced Electron Ionization (AEI) sources.
Unstoppable confidence in your investment
Rapid instrument deployment reduces time to results and revenue generation. That’s why the TSQ 9610 Triple Quadrupole GC-MS/MS System includes a comprehensive set of automated tools to provide users with a seamless experience when transitioning from other platforms, developing methods, and analyzing samples. This built-in intelligence reduces operator training needs and time to full productivity for rapid ROI.
Method development
SIM Bridge
- The SIM Bridge tool allows SIM methods exported from other sources to be translated to the TSQ 9000 system method. Those SIM methods can be immediately run on the TSQ 9000 system or through AutoSRM to translate the SIM information into a powerful SRM method.
AutoSRM
- AutoSRM is your very own mass spectrometer method development expert integrated into your system. This software walks you through the development of fully optimized SIM target ions or SRM transitions in a very simple and efficient workflow. If you like to develop from your current SIM method, SIM Bridge streamlines the workflow by importing your method details. All together, it is full MS and MS/MS method development independence, even for the less experienced user.
Timed-SRM method
- As more compounds are added to a single run, managing acquisition windows becomes increasingly complex. The TSQ 9000 system dramatically reduces this complexity by automatically optimizing the targeting of a particular compound. Simply enter the retention time and the time required to capture the peak, and t-SRM takes care of the rest. This ensures that compound detection is optimized for maximum sensitivity, and more compounds can be added to the method without compromising the excellent sensitivity of each individual analyte. The mass spectrometer is not consuming valuable resources scanning for compounds at the times when those compounds are not eluting.
Routine analysis
Retention Time Alignment (RTA)
- The new RTA tool is a faster, more flexible and easier way to maintain retention times during routine operation of high-throughput GC-MS methods. The tool uses the measured void time of the column and the retention time of a reference substance to provide a new column length and internal diameter settings (or corrected pressure or flow value) to realign retention times of all the peaks of the chromatograms. This means that during a column change or trim, the user can quickly re-align their retention times and return to collecting results.
SmartTune
- SmartTune is the new simplified tuning tool for Thermo Scientific ISQ and TSQ instruments. This intuitive tool removes tuning complexity and ensures your system is performing at the level you require, ahead of running your samples. A simple guided interface efficiently checks and tunes the system, and intelligently eliminates any unnecessary steps in the process, resulting in faster tuning operations. If a problem is detected, SmartTune advises you on recommended corrective action. In addition, SmartTune allows user customizable targets to facilitate consistency in performance between analytical sequences.
The right choice for any workflow
The TSQ 9610 Triple Quadrupole GC-MS/MS System can be seamlessly implemented into any laboratory workflow to rapidly produce trusted results. Navigate your most difficult analytical challenges and obtain results on—or even ahead of—time with automated workflows and simplified operation.
Companion software for the TSQ 9610 Triple Quadrupole GC-MS/MS System
Integrated workflow-driven software, application library, and support streamline your applications and everyday tasks including:
- Instrument optimization and troubleshooting
- Method development and implementation
- Reporting results
Unstoppable confidence in uptime for full-time productivity
Innovative technologies applied to the Thermo Scientific ISQ 7610 GC-MS and TSQ 9610 GC-MS/MS systems work together to deliver unstoppable confidence in GC-MS system performance. These technological advances enable you to minimize instrument downtime, maximize sample throughput and achieve a rapid return on your investment.
ExtractaBrite ion source
The Thermo Scientific ExtractaBrite ion source technology delivers proven rugged electron impact (EI) and chemical ionization (CI) performance. The source is removable for maintenance or switching ionization modes without breaking vacuum. In addition, by exchanging the ion source with the V-Lock source plug, GC columns can be replaced without venting.
To protect analyte integrity and maximum robustness, the ExtractaBrite ion source is comprised of highly inert material. It is also heated throughout to prevent mass analyzer contamination and to ensure matrix tolerance for high-throughput work. As a result, there is never a need to heat or clean the quadrupoles.
Advanced Electron Ionization (AEI) source
Click image to enlarge
The ultra-robust, ultra-sensitive Advanced Electron Ionization (AEI) source is available in dedicated ISQ 7610 GC-MS system configurations. On the TSQ 9610 NeverVent AEI is available; bringing the advantages of the NeverVent technology and the sensitivity and robustness of AEI together. Highly efficient ionization, a tightly focused ion beam, and heating throughout the source reduce mass spectrometer contamination, extend system uptime, and lower instrument detection limits to unprecedented levels. With ultra-high sensitivity, the AEI source can also help reduce sample concentration steps and consequent matrix pressure on the analytical system.
EvoCell
Click image to enlarge
Part of the TSQ 9610 triple quadrupole GC-MS/MS system, Enhanced Velocity Optics Collision Cell (EvoCell) technology boosts sample throughput with very high selected-reaction-monitoring (SRM) transition speeds, providing enhanced precision and sensitivity for even the most complex methods. Timed-SRM (t-SRM) software automates optimization of SRM scheduling.
EvoCell technology can be used to increase the scope of SRM methods to fit a wider range of compounds and matrices, increase sample throughput by compressing GC time, or increase method resistance to interferences, matrix effects, and retention time shifts.
XLXR
Click image to enlarge
The XLXR electron multiplier detector which extends dynamic range twofold compared to the previous design and seven time more lifetime comes as standard across the ISQ 7610 and TSQ 9610 models. Extended dynamic range capability enables labs to combine methods, including calibration curve development, allowing analysis of low- and high-concentration compounds in a single run.
NeverVent technology
Patented Thermo Scientific NeverVent technology delivers unstoppable coonfidence in GC-MS uptime. Used with the ExtractaBrite ion source, the vacuum probe interlock (VPI) and the V-Lock source plug isolate the vacuum region of the mass spectrometer from the gas chromatograph, allowing routine source cleaning, and ion source and column changing, without venting. If the NeverVent-AEI source is configured, the filament can also be changed without venting.
Dual filament
Click to enlarge
The dual filament design extends instrument uptime. Both filaments produce similar analytical performance so you can switch from one to the other without impacting analytical performance. To simplify operation, the dual filament assembly is used for both EI and CI modes.
GC-MS transferline
Independently heated zones for transfer line, ion source, and ion optics help ensure that the system stays cleaner for a longer period of time.
The optimized GC-MS transferline evenly distributes heat across the length of the analytical column, ensuring that there are no hot or cold spots, which in turn delivers Gaussian peak shapes, even for high boiling point compounds.
Ion source probes
Optional ion source probes enable you to perform real-time MS and MS/MS experiments on solid samples with easy switching between EI and CI modes. Like the ExtractaBrite ion source, the probes can be removed without venting.
Available ion source probes:
Direct Insertion Probe (DIP) for rapid analysis of components in solid matrices.
Direct Exposure Probe (DEP) for rapid molecular weight confirmation of solids dissolved or suspended in liquid solvents.
MS software innovations advance method development
The Thermo Scientific ISQ 7610 GC-MS and TSQ 9610 GC-MS/MS systems include a comprehensive set of software features for instrument tuning, and method development and optimization of targeted quantification and untargeted screening workflows. The software provides users with a seamless experience during the transition from other platforms. Intelligent instrument health monitoring helps you know when to perform planned maintenance ensures sample analysis is not interrupted due to a drop in instrument performance.
AutoSIM and Timed-SIM
AutoSIM saves time during method set up. The software provides automated, user-selectable, criteria-guided development of SIM method from full scan data, either automatically acquired by AutoSIM or imported from external data files (CSV, Excel, LIMS database).
For maximum sensitivity, Timed-SIM (t-SIM) acquisition helps users optimize the dwell times used in SIM-based quantitation of large numbers of analytes, especially for co-eluting analytes. AutoSIM can be used together with t-SIM to completely automate workflows.
SIM Bridge and AutoSRM
SIM Bridge translates SIM methods from other sources into TSQ 9610 GC-MS/MS system methods. The SIM methods can then be immediately used as-is, or converted into more powerful SRM methods using AutoSRM.
AutoSRM walks users through selection of optimum SRM transitions for TSQ 9610 GC-MS/MS system methods. Together, SIM Bridge and AutoSRM enable even less-experienced staff to rapidly develop MS and MS/MS methods.
Timed-SRM
Click image to enlarge
As compounds are added to a method, managing acquisition-time windows becomes increasingly complex. For the TSQ 9610 GC-MS/MS system, t-SRM dramatically reduces this complexity by automatically optimizing the SRM parameters needed to attain sensitive detection and quantification. The user simply enters the retention time window for the target peak, and t-SRM takes care of the rest.
Retention time alignment
Click image to enlarge
Retention Time Alignment (RTA) is a fast, flexible, and easy way to maintain retention times during high-throughput GC-MS system operation. RTA uses the void time of the column and retention time of a reference substance to provide new column dimension settings, or to correct carrier gas pressure or flow values to realign chromatographic peaks. After a column replacement or trim, the user can quickly realign the retention time.
SmartTune
Click image to enlarge
SmartTune simplifies and speeds GC-MS instrument tuning and, if needed, recommends corrective actions. This helps ensure that your system performs at the levels you require for longer periods of time.
Unstoppable confidence with a GC always ready to run
designed for a new level of usability and uptime the TRACE 1600 Series Gas Chromatograph (GC) delivers measurably more productivity and lower costs. With a unique modular design and plug-and-play injectors and detectors, you have full flexibility to perform maintenance offline and use different configurations on the same GC to make the most of your GC-MS system. When combined with the Thermo Scientific AI/AS 1610 Liquid Autosampler, the system provides easy and reliable automated sample injection to meet any sample-throughput demand.
Self-installable injector and detector modules
Minimize downtime
Automated GC consumables tracking with alerts minimizes unexpected downtime and waste due to unnecessary replacement. Instrument health is on continuous display on the touchscreen. Tubing-free injectors design allows for easy and quick septum/liner replacement, simplifying routine maintenance operations.
Perform maintenance offline
Unique Thermo Scientific iConnect injector and detector modules can be kept as interchangeable spares, allowing analyses to continue while deeper maintenance is performed offline. Simple replacement of self-installable components facilitate as well troubleshooting operations, saving time and money.
Increase laboratory efficiency
Versatile modular configurability minimizes idle time, maximizing the productive use of your laboratory’s GC systems. The suite of iConnect injectors and detectors can be shared among multiple GC systems in numerous configurations without installation costs.
Save time with robust unattended operation
The slide-in self-aligning AI/AS 1610 Liquid Autosampler provides reliable unattended sample analysis, saving valuable time and increasing productivity while improving data quality with high-precision injections.
Add the productivity of robotic sample handling
The Thermo Scientific TriPlus RSH SMART Autosampler offers advanced robotic sample handling to extend automation beyond liquid, headspace, and solid phase microextraction (SPME). Your results will benefit from improved precision and reproducibility, while your laboratory will increase productivity with flexible sample handling and automated sample preparation procedures, such as dilution, internal standard addition, and derivatization workflows.
Columns and consumables at your fingertips
Easy, reliable, and innovative, application-focused GC columns and consumables
Whether you are performing analysis in pharmaceutical, forensics/toxicology, environmental, food, petrochemical, or general analytical industries, we offer a wide range of vials, syringes, septa, liners, columns, gas filters and accessories designed to complement our GC and GC-MS systems and autosamplers in application-focused solutions.
Because time is valuable, the consumables you need for everyday workflows are available for easy online ordering and reordering, with pricing and stocking information, fast shipping, and status tracking.
- Low-bleed, high-reproducibility Thermo Scientific TraceGOLD columns
- Consumables tested and certified on TRACE 1600 Series Gas Chromatograph systems
- Vials and syringes guaranteed for use with Thermo Scientific autosamplers
- Thermo Scientific GFM Pro Gas Flowmeter and Thermo Scientific GLD Pro Gas Leak Detector for system installation and maintenance
- Derivatization reagents and derivatization-grade solvents
High-performance Thermo Scientific chromatography columns and consumables
Get the most out of your GC-MS system by pairing it with advanced, high-performance Thermo Scientific columns and consumables. Our wide range of consumables and accessories offer customers applications-focused solutions in the environmental, food safety, toxicology, clinical, petrochemical, pharmaceutical, and general analytical industries.
- Thermo Scientific TraceGOLD Columns - low bleed, high reproducibility
- Consumables tested and certified with TRACE 1600 Series GC systems
- Vials guaranteed for Thermo Scientific Autosampler systems
- Thermo Scientific GFM Pro Gas Flowmeter and Thermo Scientific GOLD Pro Gas Leak Detector for system installation and maintenance
- Derivatization reagents and derivatization-grade solvents
Workflows that help you stay ahead
Streamlined, workflow-driven software solutions such as Thermo Scientific Chromeleon Chromatography Data System (CDS) and TraceFinder software empowers your lab to successfully address productivity needs and increasingly complex regulatory requirements.
Chromeleon CDS software
Use intuitive Chromeleon CDS software to control your entire chromatography lab. It is fully scalable from a single workstation to an enterprise-wide installation, controls over 350 modules from Thermo Scientific and many other vendors, and supports quantitative MS workflows for all separation techniques. Chromeleon CDS software reduces repetitive tasks and errors, making work faster and easier while ensuring reproducible, quality results.
- Thermo Scientific Chromeleon XPS Open Access software enables untrained users to use the full power of Chromeleon to test samples in a streamlined "walk-up" interface.
- Thermo Scientific eWorkflows simplifies and speeds up creation of sample sequences. If you need to jump-start method development, download ready-to-use eWorkflows from the Thermo Scientific AppsLab Library into the Chromeleon CDS.
- The Environmental Analysis Extension Pack is a full set of predefined templates and methods that allows you to perform GC-MS environmental analysis to quickly and easily calculate results and generate reports in a manner consistent with the requirements of the U.S. EPA.
TraceFinder software
Optimized for quantitation, TraceFinder software provides an array of tools that makes targeted and untargeted analyses in food, environmental, and forensic toxicology applications simple, fast, and productive. Customized templates, automatic report generation, a method development wizard and comprehensive database, speed up the development of sensitive, robust, and reproducible quantitation methods.
Stay ahead with unstoppable confidence in GC-MS analysis
As the challenges for analytical testing expand with changing regulations, additional compounds to monitor and increased competition It is important to stay ahead. The Thermo Scientific ISQ 7610 GC single Quadrupole Mass Spectrometer offers unstoppable confidence to exceed your analytical goals.
Unstoppable confidence in quantitative performance
Click image to enlarge
Your GC-MS systems must provide the sensitivity, speed, and reproducibility required to carry out regulated methods consistently and efficiently, day after day. The ISQ 7610 Single Quadrupole GC-MS System delivers sensitive and reproducible analysis for a broad range of quantitative workflows.
Choose either the rugged Thermo Scientific ExtractaBrite ion source technology or the ultra-sensitive, ultra-robust Thermo Scientific Advanced Electron Ionization (AEI) source. Available in a dedicated system configuration, the AEI source allows you to drive down instrument detection limits and reduce time-consuming sample concentration steps.
Unstoppable instrument uptime for full-time productivity
Unplanned or planned downtime can result in poor asset utilization and reduced sample throughput. The ISQ 7610 Single Quadrupole GC-MS System features user-centric innovations that reduce downtime for routine maintenance, while instrument health monitoring assists you in determining when maintenance is needed to avoid unnecessary downtime. As a result, you maximize instrument utilization, sample throughput, and ultimately ROI.
Using NeverVent technology available with the ExtractaBrite source allows the use of the Vacuum Probe Interlock (VPI) and V-Lock source plug. This enables planned maintenance, such as changing columns and ion source cleaning, to be performed without venting the mass spectrometer, increasing uptime. The VPI can also be used to avoid venting when changing between electron ionization (EI) and chemical ionization (CI) modes.
Unstoppable return on investment
Rapid instrument deployment reduces time to results and revenue generation. That’s why the ISQ 7610 Single Quadrupole GC-MS System includes a comprehensive set of automated tools to provide users with a seamless experience when transitioning from other platforms, developing methods, and analyzing samples. This built-in intelligence reduces operator training needs and time to full productivity for rapid ROI.
Target analysis
Method development
Routine analysis
AutoSIM
AutoSIM allows you to acquire full-scan data, enter or import from external file (csv, Excel, LIMS database) your list of target analytes, and perform selection of the SIM ions from the FS data in a guided, automated fashion. A real time saver and productivity booster.
Timed-SIM method
Timed Acquisition (t-SIM) helps optimize the dwell times in SIM quantitation methods with large number of analytes, especially in case of co-elution, assuring the maximum sensitivity. However, a manual set up of t-SIM can be tedious. This is why AutoSIM is complementary to t-SIM, for a fully automated workflow.
Retention Time Alignment (RTA)
The new RTA tool uses Void Time and Retention Time of a reference substance to provide new carrier flow and pressure settings or new columns dimension settings to realign retention times of all the peaks of the chromatograms. This means that during a column change or trim, you can quickly re-align the retention times and return to collecting results.
Untargeted screening
Method development
Routine analysis
Full-scan acquisition
For untargeted analysis, leverage the easier and quick set up of a full-scan acquisition method, maintaining the analytical information of the entire mass range.
Mass spectral deconvolution
Unravel the heaviest co-elution of the TIC chromatogram by reconstructing clean mass spectra for heavy co-eluted compounds, ready for reliable library searching and ID confirmation.
Mass spectral deconvolution (continued)
SmartTune
SmartTune is the simplified tuning tool for Thermo Scientific ISQ and TSQ instruments. This intuitive tool removes tuning complexity and ensures your system is performing at the level you require, ahead of running your samples. A simple guided interface efficiently checks and tunes the system, and intelligently eliminates any unnecessary steps in the process, resulting in faster tuning operations. If a problem is detected, SmartTune advises you on recommended corrective action. In addition, SmartTune allows user customizable targets to facilitate consistency in performance between analytical sequences.
Unstoppable confidence in your future
Click image to enlarge
To ensure you are ready for any analytical challenge, the ISQ 7610 Single Quadrupole GC-MS System is fully upgradable from entry-level to advanced configurations. Now you can be confident that your laboratory can adapt to new challenges using the same investments in GC-MS technology. Select from five levels of performance with field-upgradeable options. All configurations are based on the user-centric ISQ single quadrupole design with easy-to-use tools such as SmartTune, AutoSIM, and t-SIM that facilitate adoption and method setup.
The right choice for any workflow
The ISQ 7610 Single Quadrupole GC-MS System can be implemented seamlessly into any laboratory workflow to increase efficiency. Navigate your most difficult analytical challenges and easily obtain results with automated workflows and simplified operation.
The Thermo Scientific TRACE 1600 Series GC can be coupled with sampling solutions like Purge and Trap, Thermal Desorption, and pyrolysis to analyze a breadth of environmental samples. These sampling solutions are fully controlled in Thermo Scientific Chromeleon Chromatography Data System (CDS), facilitating compliance and ensuring confidence in results. For U.S. EPA-based environmental applications, the Environmental Analysis Extension Pack available in our AppsLab method library provides a comprehensive set of GC-MS e-workflows and reporting templates.
- Fixed Calibration, Check Standards, QC Samples, Unknowns
- Tune Check, Calibration Curve, QC Samples
- Fixed Calibration, Check Standards, Injections for computing Minimum Detection Level (MDL)
- Fixed Calibration, Check Standards, Injections for performing method validation
Stay ahead with Unstoppable confidence in GC-MS/MS analysis
When sample throughput is the key to your your laboratory staying ahead, the Thermo Scientific TSQ 9610 GC Triple Quadrupole mass spectrometer offers unstoppable confidence to exceed your analytical goals.
Unstoppable confidence in quantitative performance
Click image to enlarge
Confidence in quantitation is assured with best-in-class sensitivity, speed, and reproducibility, delivered consistently, day after day. The TSQ 9610 Triple Quadrupole GC-MS/MS System provides high-sensitivity analysis with design innovations such as the ExtractaBrite ion source, highest sensitivity AEI source, and EvoCell.
Choose either the rugged Thermo Scientific ExtractaBrite ion source or the ultra-sensitive, ultra-robust ThermoScientific Advanced Electron Ionization (AEI) source. Both ionization sources can be equipped with NeverVent technology and produce consistent low level results
Unstoppable confidence in uptime for full-time productivity
Click image to enlarge
Unplanned or planned downtime can result in poor asset utilization and reduced sample throughput. TSQ 9610 Triple Quadrupole GC-MS/MS System features innovations that reduce downtime for routine maintenance, while instrument health monitoring assists you in determining when maintenance is needed to avoid unnecessary downtime. As a result, you maximize instrument utilization, sample throughput, and ultimately ROI.
Using NeverVent technology with the Vacuum Probe Interlock (VPI) and V-Lock source plug, planned maintenance such as changing column and ion source cleaning can be performed without venting the mass spectrometer, increasing uptime. NeverVent technology is available on both the Thermo Scientific ExtractaBrite and the Thermo Scientific Advanced Electron Ionization (AEI) sources.
Unstoppable confidence in your investment
Rapid instrument deployment reduces time to results and revenue generation. That’s why the TSQ 9610 Triple Quadrupole GC-MS/MS System includes a comprehensive set of automated tools to provide users with a seamless experience when transitioning from other platforms, developing methods, and analyzing samples. This built-in intelligence reduces operator training needs and time to full productivity for rapid ROI.
Method development
SIM Bridge
- The SIM Bridge tool allows SIM methods exported from other sources to be translated to the TSQ 9000 system method. Those SIM methods can be immediately run on the TSQ 9000 system or through AutoSRM to translate the SIM information into a powerful SRM method.
AutoSRM
- AutoSRM is your very own mass spectrometer method development expert integrated into your system. This software walks you through the development of fully optimized SIM target ions or SRM transitions in a very simple and efficient workflow. If you like to develop from your current SIM method, SIM Bridge streamlines the workflow by importing your method details. All together, it is full MS and MS/MS method development independence, even for the less experienced user.
Timed-SRM method
- As more compounds are added to a single run, managing acquisition windows becomes increasingly complex. The TSQ 9000 system dramatically reduces this complexity by automatically optimizing the targeting of a particular compound. Simply enter the retention time and the time required to capture the peak, and t-SRM takes care of the rest. This ensures that compound detection is optimized for maximum sensitivity, and more compounds can be added to the method without compromising the excellent sensitivity of each individual analyte. The mass spectrometer is not consuming valuable resources scanning for compounds at the times when those compounds are not eluting.
Routine analysis
Retention Time Alignment (RTA)
- The new RTA tool is a faster, more flexible and easier way to maintain retention times during routine operation of high-throughput GC-MS methods. The tool uses the measured void time of the column and the retention time of a reference substance to provide a new column length and internal diameter settings (or corrected pressure or flow value) to realign retention times of all the peaks of the chromatograms. This means that during a column change or trim, the user can quickly re-align their retention times and return to collecting results.
SmartTune
- SmartTune is the new simplified tuning tool for Thermo Scientific ISQ and TSQ instruments. This intuitive tool removes tuning complexity and ensures your system is performing at the level you require, ahead of running your samples. A simple guided interface efficiently checks and tunes the system, and intelligently eliminates any unnecessary steps in the process, resulting in faster tuning operations. If a problem is detected, SmartTune advises you on recommended corrective action. In addition, SmartTune allows user customizable targets to facilitate consistency in performance between analytical sequences.
The right choice for any workflow
The TSQ 9610 Triple Quadrupole GC-MS/MS System can be seamlessly implemented into any laboratory workflow to rapidly produce trusted results. Navigate your most difficult analytical challenges and obtain results on—or even ahead of—time with automated workflows and simplified operation.
Companion software for the TSQ 9610 Triple Quadrupole GC-MS/MS System
Integrated workflow-driven software, application library, and support streamline your applications and everyday tasks including:
- Instrument optimization and troubleshooting
- Method development and implementation
- Reporting results
Unstoppable confidence in uptime for full-time productivity
Innovative technologies applied to the Thermo Scientific ISQ 7610 GC-MS and TSQ 9610 GC-MS/MS systems work together to deliver unstoppable confidence in GC-MS system performance. These technological advances enable you to minimize instrument downtime, maximize sample throughput and achieve a rapid return on your investment.
ExtractaBrite ion source
The Thermo Scientific ExtractaBrite ion source technology delivers proven rugged electron impact (EI) and chemical ionization (CI) performance. The source is removable for maintenance or switching ionization modes without breaking vacuum. In addition, by exchanging the ion source with the V-Lock source plug, GC columns can be replaced without venting.
To protect analyte integrity and maximum robustness, the ExtractaBrite ion source is comprised of highly inert material. It is also heated throughout to prevent mass analyzer contamination and to ensure matrix tolerance for high-throughput work. As a result, there is never a need to heat or clean the quadrupoles.
Advanced Electron Ionization (AEI) source
Click image to enlarge
The ultra-robust, ultra-sensitive Advanced Electron Ionization (AEI) source is available in dedicated ISQ 7610 GC-MS system configurations. On the TSQ 9610 NeverVent AEI is available; bringing the advantages of the NeverVent technology and the sensitivity and robustness of AEI together. Highly efficient ionization, a tightly focused ion beam, and heating throughout the source reduce mass spectrometer contamination, extend system uptime, and lower instrument detection limits to unprecedented levels. With ultra-high sensitivity, the AEI source can also help reduce sample concentration steps and consequent matrix pressure on the analytical system.
EvoCell
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Part of the TSQ 9610 triple quadrupole GC-MS/MS system, Enhanced Velocity Optics Collision Cell (EvoCell) technology boosts sample throughput with very high selected-reaction-monitoring (SRM) transition speeds, providing enhanced precision and sensitivity for even the most complex methods. Timed-SRM (t-SRM) software automates optimization of SRM scheduling.
EvoCell technology can be used to increase the scope of SRM methods to fit a wider range of compounds and matrices, increase sample throughput by compressing GC time, or increase method resistance to interferences, matrix effects, and retention time shifts.
XLXR
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The XLXR electron multiplier detector which extends dynamic range twofold compared to the previous design and seven time more lifetime comes as standard across the ISQ 7610 and TSQ 9610 models. Extended dynamic range capability enables labs to combine methods, including calibration curve development, allowing analysis of low- and high-concentration compounds in a single run.
NeverVent technology
Patented Thermo Scientific NeverVent technology delivers unstoppable coonfidence in GC-MS uptime. Used with the ExtractaBrite ion source, the vacuum probe interlock (VPI) and the V-Lock source plug isolate the vacuum region of the mass spectrometer from the gas chromatograph, allowing routine source cleaning, and ion source and column changing, without venting. If the NeverVent-AEI source is configured, the filament can also be changed without venting.
Dual filament
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The dual filament design extends instrument uptime. Both filaments produce similar analytical performance so you can switch from one to the other without impacting analytical performance. To simplify operation, the dual filament assembly is used for both EI and CI modes.
GC-MS transferline
Independently heated zones for transfer line, ion source, and ion optics help ensure that the system stays cleaner for a longer period of time.
The optimized GC-MS transferline evenly distributes heat across the length of the analytical column, ensuring that there are no hot or cold spots, which in turn delivers Gaussian peak shapes, even for high boiling point compounds.
Ion source probes
Optional ion source probes enable you to perform real-time MS and MS/MS experiments on solid samples with easy switching between EI and CI modes. Like the ExtractaBrite ion source, the probes can be removed without venting.
Available ion source probes:
Direct Insertion Probe (DIP) for rapid analysis of components in solid matrices.
Direct Exposure Probe (DEP) for rapid molecular weight confirmation of solids dissolved or suspended in liquid solvents.
MS software innovations advance method development
The Thermo Scientific ISQ 7610 GC-MS and TSQ 9610 GC-MS/MS systems include a comprehensive set of software features for instrument tuning, and method development and optimization of targeted quantification and untargeted screening workflows. The software provides users with a seamless experience during the transition from other platforms. Intelligent instrument health monitoring helps you know when to perform planned maintenance ensures sample analysis is not interrupted due to a drop in instrument performance.
AutoSIM and Timed-SIM
AutoSIM saves time during method set up. The software provides automated, user-selectable, criteria-guided development of SIM method from full scan data, either automatically acquired by AutoSIM or imported from external data files (CSV, Excel, LIMS database).
For maximum sensitivity, Timed-SIM (t-SIM) acquisition helps users optimize the dwell times used in SIM-based quantitation of large numbers of analytes, especially for co-eluting analytes. AutoSIM can be used together with t-SIM to completely automate workflows.
SIM Bridge and AutoSRM
SIM Bridge translates SIM methods from other sources into TSQ 9610 GC-MS/MS system methods. The SIM methods can then be immediately used as-is, or converted into more powerful SRM methods using AutoSRM.
AutoSRM walks users through selection of optimum SRM transitions for TSQ 9610 GC-MS/MS system methods. Together, SIM Bridge and AutoSRM enable even less-experienced staff to rapidly develop MS and MS/MS methods.
Timed-SRM
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As compounds are added to a method, managing acquisition-time windows becomes increasingly complex. For the TSQ 9610 GC-MS/MS system, t-SRM dramatically reduces this complexity by automatically optimizing the SRM parameters needed to attain sensitive detection and quantification. The user simply enters the retention time window for the target peak, and t-SRM takes care of the rest.
Retention time alignment
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Retention Time Alignment (RTA) is a fast, flexible, and easy way to maintain retention times during high-throughput GC-MS system operation. RTA uses the void time of the column and retention time of a reference substance to provide new column dimension settings, or to correct carrier gas pressure or flow values to realign chromatographic peaks. After a column replacement or trim, the user can quickly realign the retention time.
SmartTune
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SmartTune simplifies and speeds GC-MS instrument tuning and, if needed, recommends corrective actions. This helps ensure that your system performs at the levels you require for longer periods of time.
Unstoppable confidence with a GC always ready to run
designed for a new level of usability and uptime the TRACE 1600 Series Gas Chromatograph (GC) delivers measurably more productivity and lower costs. With a unique modular design and plug-and-play injectors and detectors, you have full flexibility to perform maintenance offline and use different configurations on the same GC to make the most of your GC-MS system. When combined with the Thermo Scientific AI/AS 1610 Liquid Autosampler, the system provides easy and reliable automated sample injection to meet any sample-throughput demand.
Self-installable injector and detector modules
Minimize downtime
Automated GC consumables tracking with alerts minimizes unexpected downtime and waste due to unnecessary replacement. Instrument health is on continuous display on the touchscreen. Tubing-free injectors design allows for easy and quick septum/liner replacement, simplifying routine maintenance operations.
Perform maintenance offline
Unique Thermo Scientific iConnect injector and detector modules can be kept as interchangeable spares, allowing analyses to continue while deeper maintenance is performed offline. Simple replacement of self-installable components facilitate as well troubleshooting operations, saving time and money.
Increase laboratory efficiency
Versatile modular configurability minimizes idle time, maximizing the productive use of your laboratory’s GC systems. The suite of iConnect injectors and detectors can be shared among multiple GC systems in numerous configurations without installation costs.
Save time with robust unattended operation
The slide-in self-aligning AI/AS 1610 Liquid Autosampler provides reliable unattended sample analysis, saving valuable time and increasing productivity while improving data quality with high-precision injections.
Add the productivity of robotic sample handling
The Thermo Scientific TriPlus RSH SMART Autosampler offers advanced robotic sample handling to extend automation beyond liquid, headspace, and solid phase microextraction (SPME). Your results will benefit from improved precision and reproducibility, while your laboratory will increase productivity with flexible sample handling and automated sample preparation procedures, such as dilution, internal standard addition, and derivatization workflows.
Columns and consumables at your fingertips
Easy, reliable, and innovative, application-focused GC columns and consumables
Whether you are performing analysis in pharmaceutical, forensics/toxicology, environmental, food, petrochemical, or general analytical industries, we offer a wide range of vials, syringes, septa, liners, columns, gas filters and accessories designed to complement our GC and GC-MS systems and autosamplers in application-focused solutions.
Because time is valuable, the consumables you need for everyday workflows are available for easy online ordering and reordering, with pricing and stocking information, fast shipping, and status tracking.
- Low-bleed, high-reproducibility Thermo Scientific TraceGOLD columns
- Consumables tested and certified on TRACE 1600 Series Gas Chromatograph systems
- Vials and syringes guaranteed for use with Thermo Scientific autosamplers
- Thermo Scientific GFM Pro Gas Flowmeter and Thermo Scientific GLD Pro Gas Leak Detector for system installation and maintenance
- Derivatization reagents and derivatization-grade solvents
High-performance Thermo Scientific chromatography columns and consumables
Get the most out of your GC-MS system by pairing it with advanced, high-performance Thermo Scientific columns and consumables. Our wide range of consumables and accessories offer customers applications-focused solutions in the environmental, food safety, toxicology, clinical, petrochemical, pharmaceutical, and general analytical industries.
- Thermo Scientific TraceGOLD Columns - low bleed, high reproducibility
- Consumables tested and certified with TRACE 1600 Series GC systems
- Vials guaranteed for Thermo Scientific Autosampler systems
- Thermo Scientific GFM Pro Gas Flowmeter and Thermo Scientific GOLD Pro Gas Leak Detector for system installation and maintenance
- Derivatization reagents and derivatization-grade solvents
Workflows that help you stay ahead
Streamlined, workflow-driven software solutions such as Thermo Scientific Chromeleon Chromatography Data System (CDS) and TraceFinder software empowers your lab to successfully address productivity needs and increasingly complex regulatory requirements.
Chromeleon CDS software
Use intuitive Chromeleon CDS software to control your entire chromatography lab. It is fully scalable from a single workstation to an enterprise-wide installation, controls over 350 modules from Thermo Scientific and many other vendors, and supports quantitative MS workflows for all separation techniques. Chromeleon CDS software reduces repetitive tasks and errors, making work faster and easier while ensuring reproducible, quality results.
- Thermo Scientific Chromeleon XPS Open Access software enables untrained users to use the full power of Chromeleon to test samples in a streamlined "walk-up" interface.
- Thermo Scientific eWorkflows simplifies and speeds up creation of sample sequences. If you need to jump-start method development, download ready-to-use eWorkflows from the Thermo Scientific AppsLab Library into the Chromeleon CDS.
- The Environmental Analysis Extension Pack is a full set of predefined templates and methods that allows you to perform GC-MS environmental analysis to quickly and easily calculate results and generate reports in a manner consistent with the requirements of the U.S. EPA.
TraceFinder software
Optimized for quantitation, TraceFinder software provides an array of tools that makes targeted and untargeted analyses in food, environmental, and forensic toxicology applications simple, fast, and productive. Customized templates, automatic report generation, a method development wizard and comprehensive database, speed up the development of sensitive, robust, and reproducible quantitation methods.
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