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CD90 Monoclonal Antibody (5a-8), PE

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Antibody Testing Data (2)

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CD90 Antibody (MA5-17749) in Flow

Flow cytometric analysis of Balb/c mouse thymocytes stained using a CD90/Thy-1 monoclonal antibody (Product # MA5-17749) (filled histogram) or mouse IgG2b isotype control (open histogram).

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Product Details

MA5-17749

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1.0 µg/1x10^6 cells

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 3 publications 3 publications

Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

5a-8

Immunogen

CBA/J

View immunogen

Conjugate

PE PE PE

Excitation/Emission Max

565/576 nm View spectra

Form

Liquid

Concentration

0.1 mg/mL

Purification

Protein G

Storage buffer

PBS with 4-5mg/mL BSA

Contains

0.02% sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2539137

Target Information

CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Product References

B-lymphocyte depletion ameliorates Sjögren's syndrome in Id3 knockout mice.

Immunology

Hayakawa I,Tedder TF,Zhuang Y

MA5-17749 was used in flow cytometry to investigate the role of B cells in Sjogren's syndrome in a mouse model

Sat Sep 01 00:00:00 EDT 2007

Immature multipotent hemopoietic progenitors lacking long-term bone marrow-reconstituting activity in the aorta-gonad-mesonephros region of murine day 10 fetuses.

Journal of immunology (Baltimore, Md. : 1950)

Ohmura K,Kawamoto H,Lu M,Ikawa T,Ozaki S,Nakao K,Katsura Y

MA5-17749 was used in flow cytometry to examine multipotent progenitors from early fetuses.

Thu Mar 01 00:00:00 EST 2001

Commitment of common T/Natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay.

The Journal of experimental medicine

Ikawa T,Kawamoto H,Fujimoto S,Katsura Y

MA5-17749 was used in flow cytometry to describe a clonal system that supports the development of T and natural killer cells evenly.

Mon Dec 06 00:00:00 EST 1999

Emergence of T, B, and myeloid lineage-committed as well as multipotent hemopoietic progenitors in the aorta-gonad-mesonephros region of day 10 fetuses of the mouse.

Journal of immunology (Baltimore, Md. : 1950)

Ohmura K,Kawamoto H,Fujimoto S,Ozaki S,Nakao K,Katsura Y

MA5-17749 was used in flow cytometry to investigate the aorta-gonad-mesonephros region as a source of hemopoietic progenitors.

Mon Nov 01 00:00:00 EST 1999

Bioinformatics

Protein Aliases: CD90; FLJ33325; Thy 1.2; Thy-1 antigen; Thy-1 membrane glycoprotein

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Gene Aliases: CD90; T25; Thy-1; Thy-1.2; Thy1; Thy1.1; Thy1.2

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UniProt ID: (Mouse) P01831

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Entrez Gene ID: (Mouse) 21838

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Function(s)

GTPase activator activity integrin binding enzyme binding protein kinase binding GPI anchor binding cell adhesion molecule

Process(es)

angiogenesis negative regulation of protein kinase activity cytoskeleton organization single organismal cell-cell adhesion negative regulation of cell migration positive regulation of GTPase activity retinal cone cell development protein autophosphorylation focal adhesion assembly negative regulation of axonogenesis T cell receptor signaling pathway negative regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of release of sequestered calcium ion into cytosol

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CD90 Monoclonal Antibody (5a-8), PE

CD90 Antibody (MA5-17749) in Flow

Product Details

MA5-17749

Flow Cytometry (Flow)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Excitation/Emission Max

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

How to use the Panel Builder

Bioinformatics

Performance Guarantee

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