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AFDN belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton.
5033403D15Rik; Af6; Af-6; Afadin; Afadin adherens junction formation factor; afadin, adherens junction formation factor; afadin; afadin, adherens junction formation factor; AFDN; ALL1-fused gene from chromosome 6 protein; FLJ34371; Gm314; I-afadin; MLL-AF6; MLLT4; myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4; myeloid/lymphoid or mixed-lineage leukemia 4; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4; protein Af-6; RP3-431P23.3; RP3-470B24.4; S-afadin
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