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CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A is required for both MVB formation and regulation of cell cycle progression.
1500016L11Rik; BC2; BC-2; Charged multivesicular body protein 2a; CHMP2; CHMP2A; chromatin modifying protein 2A; chromatin-modifying protein 2a; fj10d05; hypothetical protein LOC523847; mVps2; putative breast adenocarcinoma marker; putative breast adenocarcinoma marker (32kD); putative breast adenocarcinoma marker BC-2; RGD1305050; Vacuolar protein sorting-associated protein 2; vacuolar protein sorting-associated protein 2-1; vacuolar protein-sorting-associated protein 2; VPS2; VPS2 homolog A; vps2-1; VPS2A; wu:fi18h03; wu:fj10d05; zgc:55361
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