Product References
An ATG12-ATG5-TECPR1 E3-like complex regulates unconventional LC3 lipidation at damaged lysosomes.
EMBO reports
Corkery DP,Castro-Gonzalez S,Knyazeva A,Herzog LK,Wu YW
Wed Sep 06 00:00:00 EDT 2023
Mammalian ATG8 proteins maintain autophagosomal membrane integrity through ESCRTs.
The EMBO journal
Javed R,Jain A,Duque T,Hendrix E,Paddar MA,Khan S,Claude-Taupin A,Jia J,Allers L,Wang F,Mudd M,Timmins G,Lidke K,Rusten TE,Akepati PR,He Y,Reggiori F,Eskelinen EL,Deretic V
Mon Jul 17 00:00:00 EDT 2023
Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy.
Microbiology spectrum
Ning B,Shen J,Liu F,Zhang H,Jiang X
Thu Jun 15 00:00:00 EDT 2023
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion.
Developmental cell
Wang F,Peters R,Jia J,Mudd M,Salemi M,Allers L,Javed R,Duque TLA,Paddar MA,Trosdal ES,Phinney B,Deretic V
Mon May 22 00:00:00 EDT 2023
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion.
Developmental cell
Wang F,Peters R,Jia J,Mudd M,Salemi M,Allers L,Javed R,Duque TLA,Paddar MA,Trosdal ES,Phinney B,Deretic V
Mon May 22 00:00:00 EDT 2023
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion.
Developmental cell
Wang F,Peters R,Jia J,Mudd M,Salemi M,Allers L,Javed R,Duque TLA,Paddar MA,Trosdal ES,Phinney B,Deretic V
Mon May 22 00:00:00 EDT 2023
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion.
Developmental cell
Wang F,Peters R,Jia J,Mudd M,Salemi M,Allers L,Javed R,Duque TLA,Paddar MA,Trosdal ES,Phinney B,Deretic V
Mon May 22 00:00:00 EDT 2023
Downregulation of YAP Activity Restricts P53 Hyperactivation to Promote Cell Survival in Confinement.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Hemmati F,Akinpelu A,Song J,Amiri F,McDaniel A,McMurray C,Afthinos A,Andreadis ST,Aitken AV,Biancardi VC,Gerecht S,Mistriotis P
Tue Aug 01 00:00:00 EDT 2023
CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity.
Nature communications
Bernareggi D,Xie Q,Prager BC,Yun J,Cruz LS,Pham TV,Kim W,Lee X,Coffey M,Zalfa C,Azmoon P,Zhu H,Tamayo P,Rich JN,Kaufman DS
Thu Apr 07 00:00:00 EDT 2022
Polymyxin B Reduces Brain Injury in Ischemic Stroke Rat Through a Mechanism Involving Targeting ESCRT-III Machinery and RIPK1/RIPK3/MLKL Pathway.
Journal of cardiovascular translational research
Tian J,Zhang YY,Peng YW,Liu B,Zhang XJ,Hu ZY,Hu CP,Luo XJ,Peng J
Sat Oct 01 00:00:00 EDT 2022
V. cholerae MakA is a cholesterol-binding pore-forming toxin that induces non-canonical autophagy.
The Journal of cell biology
Jia X,Knyazeva A,Zhang Y,Castro-Gonzalez S,Nakamura S,Carlson LA,Yoshimori T,Corkery DP,Wu YW
Mon Dec 05 00:00:00 EST 2022
ATG9A protects the plasma membrane from programmed and incidental permeabilization.
Nature cell biology
Claude-Taupin A,Jia J,Bhujabal Z,Garfa-Traoré M,Kumar S,da Silva GPD,Javed R,Gu Y,Allers L,Peters R,Wang F,da Costa LJ,Pallikkuth S,Lidke KA,Mauthe M,Verlhac P,Uchiyama Y,Salemi M,Phinney B,Tooze SA,Mari MC,Johansen T,Reggiori F,Deretic V
Sun Aug 01 00:00:00 EDT 2021
An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress.
Molecular cell
Nüchel J,Tauber M,Nolte JL,Mörgelin M,Türk C,Eckes B,Demetriades C,Plomann M
Thu Aug 19 00:00:00 EDT 2021
Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes.
Cell
Kumar S,Javed R,Mudd M,Pallikkuth S,Lidke KA,Jain A,Tangavelou K,Gudmundsson SR,Ye C,Rusten TE,Anonsen JH,Lystad AH,Claude-Taupin A,Simonsen A,Salemi M,Phinney B,Li J,Guo LW,Bradfute SB,Timmins GS,Eskelinen EL,Deretic V
Wed Nov 24 00:00:00 EST 2021
AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody.
PLoS genetics
Merigliano C,Burla R,La Torre M,Del Giudice S,Teo H,Liew CW,Chojnowski A,Goh WI,Olmos Y,Maccaroni K,Giubettini M,Chiolo I,Carlton JG,Raimondo D,Vernì F,Stewart CL,Rhodes D,Wright GD,Burke BE,Saggio I
Sun Aug 01 00:00:00 EDT 2021
Loss of Coiled-Coil Protein Cep55 Impairs Neural Stem Cell Abscission and Results in p53-Dependent Apoptosis in Developing Cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Little JN,McNeely KC,Michel N,Bott CJ,Lettieri KS,Hecht MR,Martin SA,Dwyer ND
Wed Apr 14 00:00:00 EDT 2021
Targeting the ESCRT-III component CHMP2A for noncanonical Caspase-8 activation on autophagosomal membranes.
Cell death and differentiation
Hattori T,Takahashi Y,Chen L,Tang Z,Wills CA,Liang X,Wang HG
Mon Feb 01 00:00:00 EST 2021
PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure.
Cell death & disease
Wang H,Wang Y,Wang X,Huang H,Bao J,Zhong W,Li A
Tue Nov 16 00:00:00 EST 2021
The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model.
Nature communications
Yuste-Checa P,Trinkaus VA,Riera-Tur I,Imamoglu R,Schaller TF,Wang H,Dudanova I,Hipp MS,Bracher A,Hartl FU
Wed Aug 11 00:00:00 EDT 2021
CDK1 controls CHMP7-dependent nuclear envelope reformation.
eLife
Gatta AT,Olmos Y,Stoten CL,Chen Q,Rosenthal PB,Carlton JG
Wed Jul 21 00:00:00 EDT 2021
ER-directed TREX1 limits cGAS activation at micronuclei.
Molecular cell
Mohr L,Toufektchan E,von Morgen P,Chu K,Kapoor A,Maciejowski J
Thu Feb 18 00:00:00 EST 2021
The balance between AIM2-associated inflammation and autophagy: the role of CHMP2A in brain injury after cardiac arrest.
Journal of neuroinflammation
Shao R,Wang X,Xu T,Xia Y,Cui D
Fri Nov 05 00:00:00 EDT 2021
The balance between AIM2-associated inflammation and autophagy: the role of CHMP2A in brain injury after cardiac arrest.
Journal of neuroinflammation
Shao R,Wang X,Xu T,Xia Y,Cui D
Fri Nov 05 00:00:00 EDT 2021
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Nature cell biology
Mercier V,Larios J,Molinard G,Goujon A,Matile S,Gruenberg J,Roux A
Sat Aug 01 00:00:00 EDT 2020
A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5α.
PLoS pathogens
Saha B,Chisholm D,Kell AM,Mandell MA
Thu Oct 01 00:00:00 EDT 2020
Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles.
Proceedings of the National Academy of Sciences of the United States of America
Liese S,Wenzel EM,Kjos I,Rojas Molina R,Schultz SW,Brech A,Stenmark H,Raiborg C,Carlson A
Tue Nov 17 00:00:00 EST 2020
ESCRT-mediated phagophore sealing during mitophagy.
Autophagy
Zhen Y,Spangenberg H,Munson MJ,Brech A,Schink KO,Tan KW,Sørensen V,Wenzel EM,Radulovic M,Engedal N,Simonsen A,Raiborg C,Stenmark H
Fri May 01 00:00:00 EDT 2020
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation.
Nature cell biology
Vietri M,Schultz SW,Bellanger A,Jones CM,Petersen LI,Raiborg C,Skarpen E,Pedurupillay CRJ,Kjos I,Kip E,Timmer R,Jain A,Collas P,Knorr RL,Grellscheid SN,Kusumaatmaja H,Brech A,Micci F,Stenmark H,Campsteijn C
Wed Jul 01 00:00:00 EDT 2020
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation.
Nature cell biology
Vietri M,Schultz SW,Bellanger A,Jones CM,Petersen LI,Raiborg C,Skarpen E,Pedurupillay CRJ,Kjos I,Kip E,Timmer R,Jain A,Collas P,Knorr RL,Grellscheid SN,Kusumaatmaja H,Brech A,Micci F,Stenmark H,Campsteijn C
Wed Jul 01 00:00:00 EDT 2020
Studying the Spatial Organization of ESCRTs in Cytokinetic Abscission Using the High-Resolution Imaging Techniques SIM and Cryo-SXT.
Methods in molecular biology (Clifton, N.J.)
Adar-Levor S,Goliand I,Elbaum M,Elia N
Mon Mar 02 00:00:00 EST 2020
Nuclear envelope assembly defects link mitotic errors to chromothripsis.
Nature
Liu S,Kwon M,Mannino M,Yang N,Renda F,Khodjakov A,Pellman D
Sat Sep 01 00:00:00 EDT 2018
Nuclear envelope assembly defects link mitotic errors to chromothripsis.
Nature
Liu S,Kwon M,Mannino M,Yang N,Renda F,Khodjakov A,Pellman D
Sat Sep 01 00:00:00 EDT 2018
Nonenvelopment Role for the ESCRT-III Complex during Human Cytomegalovirus Infection.
Journal of virology
Streck NT,Carmichael J,Buchkovich NJ
Fri Jun 15 00:00:00 EDT 2018
Nonenvelopment Role for the ESCRT-III Complex during Human Cytomegalovirus Infection.
Journal of virology
Streck NT,Carmichael J,Buchkovich NJ
Fri Jun 15 00:00:00 EDT 2018
VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis.
Scientific reports
Ott C,Nachmias D,Adar S,Jarnik M,Sherman S,Birnbaum RY,Lippincott-Schwartz J,Elia N
Tue Feb 20 00:00:00 EST 2018
VPS4 is a dynamic component of the centrosome that regulates centrosome localization of γ-tubulin, centriolar satellite stability and ciliogenesis.
Scientific reports
Ott C,Nachmias D,Adar S,Jarnik M,Sherman S,Birnbaum RY,Lippincott-Schwartz J,Elia N
Tue Feb 20 00:00:00 EST 2018
CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope.
Developmental cell
Ventimiglia LN,Cuesta-Geijo MA,Martinelli N,Caballe A,Macheboeuf P,Miguet N,Parnham IM,Olmos Y,Carlton JG,Weissenhorn W,Martin-Serrano J
Mon Dec 03 00:00:00 EST 2018
Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM.
Cell reports
Goliand I,Adar-Levor S,Segal I,Nachmias D,Dadosh T,Kozlov MM,Elia N
Tue Aug 14 00:00:00 EDT 2018
Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM.
Cell reports
Goliand I,Adar-Levor S,Segal I,Nachmias D,Dadosh T,Kozlov MM,Elia N
Tue Aug 14 00:00:00 EDT 2018
ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival.
The EMBO journal
Radulovic M,Schink KO,Wenzel EM,Nähse V,Bongiovanni A,Lafont F,Stenmark H
Fri Nov 02 00:00:00 EDT 2018
An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure.
Nature communications
Takahashi Y,He H,Tang Z,Hattori T,Liu Y,Young MM,Serfass JM,Chen L,Gebru M,Chen C,Wills CA,Atkinson JM,Chen H,Abraham T,Wang HG
Fri Jul 20 00:00:00 EDT 2018
An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure.
Nature communications
Takahashi Y,He H,Tang Z,Hattori T,Liu Y,Young MM,Serfass JM,Chen L,Gebru M,Chen C,Wills CA,Atkinson JM,Chen H,Abraham T,Wang HG
Fri Jul 20 00:00:00 EDT 2018
Nuclear Envelope Rupture Is Enhanced by Loss of p53 or Rb.
Molecular cancer research : MCR
Yang Z,Maciejowski J,de Lange T
Wed Nov 01 00:00:00 EDT 2017
Nuclear Envelope Rupture Is Enhanced by Loss of p53 or Rb.
Molecular cancer research : MCR
Yang Z,Maciejowski J,de Lange T
Wed Nov 01 00:00:00 EDT 2017
Membrane Binding by CHMP7 Coordinates ESCRT-III-Dependent Nuclear Envelope Reformation.
Current biology : CB
Olmos Y,Perdrix-Rosell A,Carlton JG
Mon Oct 10 00:00:00 EDT 2016
Membrane Binding by CHMP7 Coordinates ESCRT-III-Dependent Nuclear Envelope Reformation.
Current biology : CB
Olmos Y,Perdrix-Rosell A,Carlton JG
Mon Oct 10 00:00:00 EDT 2016
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Nature
Vietri M,Schink KO,Campsteijn C,Wegner CS,Schultz SW,Christ L,Thoresen SB,Brech A,Raiborg C,Stenmark H
Thu Jun 11 00:00:00 EDT 2015
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Nature
Vietri M,Schink KO,Campsteijn C,Wegner CS,Schultz SW,Christ L,Thoresen SB,Brech A,Raiborg C,Stenmark H
Thu Jun 11 00:00:00 EDT 2015
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Nature
Vietri M,Schink KO,Campsteijn C,Wegner CS,Schultz SW,Christ L,Thoresen SB,Brech A,Raiborg C,Stenmark H
Thu Jun 11 00:00:00 EDT 2015
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Nature
Vietri M,Schink KO,Campsteijn C,Wegner CS,Schultz SW,Christ L,Thoresen SB,Brech A,Raiborg C,Stenmark H
Thu Jun 11 00:00:00 EDT 2015
ESCRT-III controls nuclear envelope reformation.
Nature
Olmos Y,Hodgson L,Mantell J,Verkade P,Carlton JG
Thu Jun 11 00:00:00 EDT 2015
ESCRT-III controls nuclear envelope reformation.
Nature
Olmos Y,Hodgson L,Mantell J,Verkade P,Carlton JG
Thu Jun 11 00:00:00 EDT 2015
ESCRT-III controls nuclear envelope reformation.
Nature
Olmos Y,Hodgson L,Mantell J,Verkade P,Carlton JG
Thu Jun 11 00:00:00 EDT 2015
ESCRT-III controls nuclear envelope reformation.
Nature
Olmos Y,Hodgson L,Mantell J,Verkade P,Carlton JG
Thu Jun 11 00:00:00 EDT 2015
MITD1 is recruited to midbodies by ESCRT-III and participates in cytokinesis.
Molecular biology of the cell
Lee S,Chang J,Renvoisé B,Tipirneni A,Yang S,Blackstone C
Thu Nov 01 00:00:00 EDT 2012
MITD1 is recruited to midbodies by ESCRT-III and participates in cytokinesis.
Molecular biology of the cell
Lee S,Chang J,Renvoisé B,Tipirneni A,Yang S,Blackstone C
Thu Nov 01 00:00:00 EDT 2012
Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15.
Journal of virology
Kuang Z,Seo EJ,Leis J
Fri Jul 01 00:00:00 EDT 2011
Mechanism of inhibition of retrovirus release from cells by interferon-induced gene ISG15.
Journal of virology
Kuang Z,Seo EJ,Leis J
Fri Jul 01 00:00:00 EDT 2011