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CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein family. These proteins are components of ESCRT-III, a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies. Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
2210412K09Rik; apoptosis-related protein PNAS-2; AW545668; C9orf83; CGI-34; Charged multivesicular body protein 5; CHMP5; chromatin modifying protein 5; chromatin-modifying protein 5; HGNC:26942; HSPC177; hVps60; likely ortholog of H. sapiens SNF7 domain containing 2; PNAS-114; PNAS-2; SNF7 domain containing 2; SNF7 domain-containing protein 2; SNF7DC2; Vacuolar protein sorting-associated protein 60; Vps60
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