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EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
6330520A15Rik; BC026645; Ca2+ release-activated Ca2+ (CRAC) channel regulator 2B; calcium release activated channel regulator 2B; calcium release-activated calcium channel regulator 2B; Calcium release-activated channel regulator 2B; CRAC channel regulator 2B; CRAC regulator 2B; Cracr2a; CRACR2B; Efcab4; EFCAB4A; EF-hand calcium binding domain 4A; EF-hand calcium-binding domain-containing protein 4A; RGD1560911
100 µL
100 µg
100 µg
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