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GATA2 (GATA binding protein 2) belongs to the GATA family of transcription factors. GATA proteins play a very important role in signaling pathways controlling proliferation and differentiation of erythroid progenitor cells. There are 6 transcription factors in the GATA family: GATA1 to GATA6. GATA2 is a transcriptional activator regulating endothelin-1 gene expression in endothelial cells. It also appears to be involved in differentiation of other tissue types (uro-genital and nervous) during embryogenesis.
DCML; EMBL:AAK51128.1}; Endothelial transcription factor GATA-2; FLJ45948; GATA binding protein 2; GATA binding protein 3; GATA2; Gata-2; gata2 {ECO:0000312; GATA3; GATA-binding factor 3; GATA-binding protein 2; GATA-bindning protein 2; HDR; HDRS; IMD21; MGC2306; MONOMAC; NFE1B; trans-acting T-cell-specific transcription factor GATA-3; uterine GATA-4 transcription factor
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