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The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
Bruton agammaglobulinemia tyrosine kinase inhibitor; BTBD26; BTK-binding protein; BTKI; IBTK; Inhibitor of Bruton tyrosine kinase; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma; KIAA1417; RP1-93K22.1
100 µL
100 µL
50 µg
100 µL
100 µL
100 µg
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