Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
0
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bruton agammaglobulinemia tyrosine kinase inhibitor; BTK-binding protein; IBtk; Inhibitor of Bruton tyrosine kinase; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma; RP1-93K22.1
Gene Aliases: BTBD26; BTKI; IBTK; KIAA1417
UniProt ID: (Human) Q9P2D0
Entrez Gene ID: (Human) 25998
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support