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IL-28B encodes a cytokine distantly related to type I interferons and the IL-10 family. IL-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Cytokine Zcyto22; IFL-1; Ifnl3; IFN-lambda 3; IFN-lambda-3; IFN-lambda-4; Il28; Il28b; IL-28B; IL28C; IL-28C; ILN; INF-alpha; INF-lambda; interferon alpha; interferon lambda 3; interferon lambda-3; Interferon lambda-4; interferon, lambda 3; interferon, lambda 4; Interleukin; interleukin 28; interleukin 28B; interleukin 28C; interleukin-28B; Interleukin-28C; ZCYTO22
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