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Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012].
AI314697; CRSDA; Enhancer trap locus homolog 2; Etl2; etl-2; GP130; IL-11 receptor subunit alpha; IL-11 receptor subunit alpha-1; IL-11R subunit alpha; IL-11R subunit alpha-1; Il11ra; IL-11RA; Il11ra1; IL-11RA1; Il11ra2; Il-11ra-alpha; IL-11R-alpha; IL-11R-alpha-1; interleukin 11 receptor subunit alpha; interleukin 11 receptor, alpha; interleukin 11 receptor, alpha chain 1; interleukin 11 receptor, alpha chain 2; interleukin-11 receptor alpha chain; interleukin-11 receptor subunit alpha; Interleukin-11 receptor subunit alpha-1; locus 2; novel cytokine receptor 1; NR1; NR-1; sIL11RA
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