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Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
2310015I08Rik; Hippostasin; hK11; kallikrein 11; kallikrein related peptidase 11; kallikrein related-peptidase 11; Kallikrein11; kallikrein-11; Kallikrein-11 inactive chain 1; Kallikrein-11 inactive chain 2; kallikrein-related peptidase 11; KLK11; protease, serine, 20; Prss20; Serine protease 20; TLSP; Trypsin-like protease; UNQ649/PRO1279
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