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LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
9130006H11Rik; AI325176; DLG4; HGL; HUGL; HUGL1; HUGL-1; Hugl-2; human giant larvae homolog; human homolog to the D-lgl gene protein; lethal giant larvae homolog 1; lethal giant larvae homolog 1 (Drosophila); lethal giant larvae homolog 1, scribble cell polarity complex component; lethal giant larvae homolog 2; lethal giant larvae homolog 2 (Drosophila); lethal giant larvae homolog 2, scribble cell polarity complex component; lethal giant larvae-like protein 2; Lethal(2) giant larvae protein homolog 1; lethal(2) giant larvae protein homolog 2; Lgl1; LGL2; LLGL; LLGL scribble cell polarity complex component 2; Llgl1; LLGL1, scribble cell polarity complex component; Llgl2; LLGL2, scribble cell polarity complex component; Llglh; Llglh2; Mgl1; Mgl-1; mlgl; RGD1560307; Rgl1; Rgl-1
100 µL
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