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OBFC1 is a component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
0610009H20Rik; 2310057J23Rik; AAF44; AAF-44; AI413458; alpha accessory factor 44; alpha-accessory factor of 44 kDa; bA541N10.2; CST complex subunit STN1; Obfc1; oligonucleotide/oligosaccharide binding fold containing 1; oligonucleotide/oligosaccharide-binding fold containing 1; oligonucleotide/oligosaccharide-binding fold-containing protein 1; replication protein A 32 kDa subunit; RPA-32; STN1; STN1 subunit of CST complex; STN1, CST complex subunit; suppressor of cdc thirteen homolog
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