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PHD finger protein 8 is a jumonji domain containing protein. Like other members of the jumonji family, PHF8 may therefore play a role in histone demethylation. Mutations in PHF8 lead to Siderius type X-linked mental retardation (MRXSSD), a mild to borderline type of mental retardation.
9830141C09Rik; histone lysine demethylase PHF8; JHDM1F; jumonji C domain-containing histone demethylase 1F; Kiaa1111; mKIAA1111; MRXSSD; PHD finger protein 8; PHF8; RGD1561065; ZNF422
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