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The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis.
29B; 6330556D22Rik; 65 kDa regulatory subunit of protein phosphatase; A/PR65; alpha isoform of regulatory subunit A, protein phosphatase 2; CG13383; CG17291; CG17291-PA; CG17291-PB; CG17291-PC; CG17291-PD; CG17291-PE; CG33297; Dmel\CG17291; Dmel_CG17291; dPP2A A; DPR65; Medium tumor antigen-associated 61 kDa protein; MGC786; MRD36; PP2A; PP2A 29B; PP2A 65kD subunit A; PP2A A; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha; PP2A[A]; Pp2A29B; PP2A-29B; Pp2A-29B-PA; Pp2A-29B-PB; Pp2A-29B-PC; Pp2A-29B-PD; Pp2A-29B-PE; PP2A-A; PP2AAALPHA; PP2A-Aalpha; PP2Ac; PP2CA; PP2Calpha; Ppp2r1a; PR65; PR65A; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; protein phosphatase 2 regulatory subunit A, alpha; protein phosphatase 2 scaffold subunit Aalpha; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2A; protein phosphatase 2A at 29B; protein phosphatase PP2A; Protein phosphatase PP2A regulatory subunit A; protein phosphate 2A; regulatory subunit A of type 2A protein phosphatase; RP-C; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform; serine/threonine protein phosphatase A subunit type 2A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit; testicular secretory protein Li 1; Unknown (protein for MGC:128399)
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