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This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
1200003J11Rik; 1700069J21Rik; Aa1076; AA930106; CALCOCO3; D6Ertd404e; D6Ertd772e; liver regeneration-related protein 2; liver regeneration-related protein LRRG004; PRO0105; T6BP; Tax1 (human T cell leukemia virus type I) binding protein 1; Tax1 (human T-cell leukemia virus type I) binding protein 1; Tax1 binding protein 1; tax1-binding protein 1; Tax1-binding protein 1 homolog; TAX1BP1; TRAF6-binding protein; TRAF6-binding protein homolog; TXBP151
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