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TRAIP is a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
E3 ubiquitin-protein ligase TRAIP; RING finger protein 206; RING-type E3 ubiquitin transferase TRAIP; RNF206; SCKL9; TRAF interacting protein; TRAF-interacting protein; TRAIP; Trip
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