Product References
CD14+ monocytes and soluble CD14 of synovial fluid are associated with osteoarthritis progression.
Archives of rheumatology
Lee HR,Lee S,Yoo IS,Yoo SJ,Kwon MH,Joung CI,Park JA,Wook Kang S,Kim J
11-0149-42 was used in Flow cytometry/Cell sorting to suggest that CD14+ monocytes and the sCD14-mediated pathway play an important role in OA aggravation through inflammatory cytokine secretion.
Thu Sep 01 00:00:00 EDT 2022
Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1 oncogenic functions in AML.
Oncogene
Nicosia L,Boffo FL,Ceccacci E,Conforti F,Pallavicini I,Bedin F,Ravasio R,Massignani E,Somervaille TCP,Minucci S,Bonaldi T
11-0149-42 was used in Flow cytometry/Cell sorting to offer new insights into GSE1 as a novel therapeutic target for acute myeloid leukemia (AML).
Tue Feb 01 00:00:00 EST 2022
M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway.
Cell death & disease
Jiang H,Zhou L,Shen N,Ning X,Wu D,Jiang K,Huang X
11-0149-42 was used in Flow Cytometry to explore the function of M1-derived exosomes and clarify their specific mechanism in head and neck squamous cell carcinoma (HNSCC).
Thu Feb 24 00:00:00 EST 2022
MicroRNA 573 Rescues Endothelial Dysfunction during Dengue Virus Infection under PPARγ Regulation.
Journal of virology
Banerjee S,Xin CW,Chu JJH
11-0149-42 was used in Flow cytometry/Cell sorting to show that miR-573 rescues endothelial permeability and is downregulated during DENV2 infection in endothelial cells.
Wed Mar 23 00:00:00 EDT 2022
Placenta-derived IL-32β activates neutrophils to promote preeclampsia development.
Cellular & molecular immunology
Liu D,Li Q,Ding H,Zhao G,Wang Z,Cao C,Dai Y,Zheng M,Zhu X,Wu Q,Wang Y,Duan H,Tang H,Lu X,Hou Y,Hu Y
11-0149-42 was used in Flow Cytometry to investigate whether IL-32 is expressed in the placenta and whether it contributes to the activation of neutrophils in preeclampsia patients.
Thu Apr 01 00:00:00 EDT 2021
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.
The Journal of experimental medicine
Louka E,Povinelli B,Rodriguez-Meira A,Buck G,Wen WX,Wang G,Sousos N,Ashley N,Hamblin A,Booth CAG,Roy A,Elliott N,Iskander D,de la Fuente J,Fordham N,O'Byrne S,Inglott S,Norfo R,Salio M,Thongjuea S,Rao A,Roberts I,Mead AJ
11-0149-42 was used in Flow Cytometry to pave the way for LSC-directed disease monitoring and therapy in this disease.
Mon Feb 01 00:00:00 EST 2021
Smac-mimetics reduce numbers and viability of human osteoclasts.
Cell death discovery
Moen IN,Westhrin M,Håland E,Haug M,Nonstad U,Klaharn M,Standal T,Starheim KK
11-0149-42 was used in Flow Cytometry to show that SM reduces human osteoclastogenesis, and that these compounds may represent promising drug candidates for pathological bone degradation.
Fri Feb 19 00:00:00 EST 2021
NAD Modulates DNA Methylation and Cell Differentiation.
Cells
Ummarino S,Hausman C,Gaggi G,Rinaldi L,Bassal MA,Zhang Y,Seelam AJ,Kobayashi IS,Borchiellini M,Ebralidze AK,Ghinassi B,Trinh BQ,Kobayashi SS,Di Ruscio A
11-0149-42 was used in Flow Cytometry to present a novel epigenetic effect of the essential nutrient NAD.
Tue Nov 02 00:00:00 EDT 2021
Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells.
Stem cell research & therapy
Liu W,Zhou N,Liu Y,Zhang W,Li X,Wang Y,Zheng R,Zhang Y
11-0149-42 was used in Flow cytometry/Cell sorting to unveil a new role of MSCs-Exo containing miR-223 in the treatment of acute graft-versus-host disease (aGvHD).
Fri Feb 26 00:00:00 EST 2021
Glycemic control by umbilical cord-derived mesenchymal stem cells promotes effects of fasting-mimicking diet on type 2 diabetic mice.
Stem cell research & therapy
Zhao N,Gao YF,Bao L,Lei J,An HX,Pu FX,Cheng RP,Chen J,Ni H,Sui BD,Ji FP,Hu CH
11-0149-42 was used in Flow Cytometry to establish a strategy that combined UC-MSC infusion and FMD and was effective in treating T2D, which provided potential approaches for developing novel clinical T2D therapies.
Tue Jul 13 00:00:00 EDT 2021
Diurnal Variation of Plasma Extracellular Vesicle Is Disrupted in People Living with HIV.
Pathogens (Basel, Switzerland)
Bazié WW,Goyer B,Boucher J,Zhang Y,Planas D,Chatterjee D,Routy JP,Alary M,Ancuta P,Gilbert C
11-0149-42 was used in Flow Cytometry to investigate daily variations of large and small EVs, in terms of abundance and microRNA contents in people living with HIV (PLWH) receiving antiretroviral therapy (HIV+ART) and uninfected controls (HIV-).
Sat Apr 24 00:00:00 EDT 2021
Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells.
Immunity
Bourdely P,Anselmi G,Vaivode K,Ramos RN,Missolo-Koussou Y,Hidalgo S,Tosselo J,Nuñez N,Richer W,Vincent-Salomon A,Saxena A,Wood K,Lladser A,Piaggio E,Helft J,Guermonprez P
11-0149-41 was used in Flow Cytometry to define DC3s as a lineage of inflammatory DCs endowed with a strong potential to regulate tumor immunity.
Tue Aug 18 00:00:00 EDT 2020
Body fluid from the parasitic worm Ascaris suum inhibits broad-acting pro-inflammatory programs in dendritic cells.
Immunology
Arora P,Moll JM,Andersen D,Workman CT,Williams AR,Kristiansen K,Brix S
11-0149 was used in Flow cytometry/Cell sorting to compare the ability of a selected number of molecules to modulate the pro-inflammatory phenotype of lipopolysaccharide (LPS) and interferon-γ (IFN-γ)-stimulated human monocyte-derived DCs towards an anti-inflammatory or regulatory phenotype, including Ascaris suum body fluid [helminth pseudocoelomic fluid (PCF)], the metabolites succinate and butyrate, and the type 2 cytokines thymic stromal lymphopoietin and interleukin-25.
Sun Mar 01 00:00:00 EST 2020
Impact of mature dendritic cells pulsed with a novel WT1 helper peptide on the induction of HLA‑A2‑restricted WT1‑reactive CD8+ T cells.
International journal of oncology
Kan S,Bito T,Shimabuku M,Taguchi J,Ohkusa T,Shimodaira S,Sugiyama H,Koido S
11-0149-42 was used in Flow Cytometry to study the impact of mature dendritic cells pulsed with a novel WT1 helper peptide on the induction of HLA-A2-restricted WT1 reactive CD8+ T cells.
Thu Oct 01 00:00:00 EDT 2020
CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling.
Laboratory investigation; a journal of technical methods and pathology
Zhang X,Chen L,Dang WQ,Cao MF,Xiao JF,Lv SQ,Jiang WJ,Yao XH,Lu HM,Miao JY,Wang Y,Yu SC,Ping YF,Liu XD,Cui YH,Zhang X,Bian XW
11-0149 was used in Flow cytometry/Cell sorting to demonstrate that chemokine (C-C motif) ligand 8 (CCL8) is highly expressed by TAMs and contributes to pseudopodia formation by GBM cells.
Wed Apr 01 00:00:00 EDT 2020
PF-127 hydrogel plus sodium ascorbyl phosphate improves Wharton's jelly mesenchymal stem cell-mediated skin wound healing in mice.
Stem cell research & therapy
Deng Q,Huang S,Wen J,Jiao Y,Su X,Shi G,Huang J
11-0149-42 was used in Flow cytometry/Cell sorting to investigate the role of Pluronic F-127 (PF-127) hydrogel plus antioxidant sodium ascorbyl phosphate (SAP) in enhancing Wharton's jelly mesenchymal stem cell (WJMSC)-mediated effectiveness on full-thickness skin wound healing in mice.
Fri Apr 03 00:00:00 EDT 2020
MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization.
International journal of biological sciences
Zhu X,Liu H,Zhang Z,Wei R,Zhou X,Wang Z,Zhao L,Guo Q,Zhang Y,Chu C,Wang L,Li X
11-0149 was used in Flow cytometry/Cell sorting to prove decreased miR-103 is involved in RSA by increasing M1 macrophage polarization via promoting STAT1/IRF1 signaling pathway. miR-103 may be explored as a promising diagnostic marker and therapeutic target for RSA.
Fri Nov 12 00:00:00 EST 2021
Biological Therapy in Inflammatory Bowel Disease Patients Partly Restores Intestinal Innate Lymphoid Cell Subtype Equilibrium.
Frontiers in immunology
Creyns B,Jacobs I,Verstockt B,Cremer J,Ballet V,Vandecasteele R,Vanuytsel T,Ferrante M,Vermeire S,Van Assche G,Ceuppens JL,Breynaert C
11-0149 was used in Flow cytometry/Cell sorting to study the impact of biological treatment on innate lymphoid cells in Crohn disease and ulcerative colitis.
Mon Apr 12 00:00:00 EDT 2021
Development of CAR-T cell therapy for B-ALL using a point-of-care approach.
Oncoimmunology
de Macedo Abdo L,Barros LRC,Saldanha Viegas M,Vieira Codeço Marques L,de Sousa Ferreira P,Chicaybam L,Bonamino MH
11-0149 was used in Flow cytometry/Cell sorting to demonstrate that the POC approach is a viable alternative for the generation and use of CAR-T cells, overcoming the limitations of current manufacturing protocols.
Wed Jul 14 00:00:00 EDT 2021
An Advanced Human Intestinal Coculture Model Reveals Compartmentalized Host and Pathogen Strategies during Salmonella Infection.
mBio
Schulte LN,Schweinlin M,Westermann AJ,Janga H,Santos SC,Appenzeller S,Walles H,Vogel J,Metzger M
11-0149 was used in Flow cytometry/Cell sorting to propose the adoption of similar 3D tissue models to infection biology, to advance our understanding of molecular infection strategies employed by bacterial pathogens in their human host.
Tue Feb 18 00:00:00 EST 2020
CD62L Is a Functional and Phenotypic Marker for Circulating Innate Lymphoid Cell Precursors.
Journal of immunology (Baltimore, Md. : 1950)
Bar-Ephraim YE,Koning JJ,Burniol Ruiz E,Konijn T,Mourits VP,Lakeman KA,Boon L,Bögels M,van Maanen JP,Den Haan JMM,van Egmond M,Bouma G,Reijmers RM,Mebius RE
11-0149-42 was used in Flow Cytometry to demonstrate that CD62L not only serves as a functional marker of ILCP, but has potential to be used in the clinic as a diagnostic marker in inflammatory disorders.
Tue Jan 01 00:00:00 EST 2019
Lipopolysaccharides from Microcystis Cyanobacteria-Dominated Water Bloom and from Laboratory Cultures Trigger Human Immune Innate Response.
Toxins
Moosová Z,Šindlerová L,Ambrůzová B,Ambrožová G,Vašíček O,Velki M,Babica P,Kubala L
11-0149 was used in Flow cytometry/Cell sorting to study the biological activities of lipopolysaccharide isolated from Microcystis aeruginosa, the most prominent cyanobacteria in water bloom.
Thu Apr 11 00:00:00 EDT 2019
STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research
Moreira D,Adamus T,Zhao X,Su YL,Zhang Z,White SV,Swiderski P,Lu X,DePinho RA,Pal SK,Kortylewski M
11-0149 was used in Flow cytometry/Cell sorting to show a novel strategy combining STAT3 inhibition with Toll-like Receptor 9 (TLR9) stimulation to unleash immune response against prostate cancers regardless of the genetic background.
Sat Dec 01 00:00:00 EST 2018
Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1.
Journal of immunology (Baltimore, Md. : 1950)
Walwyn-Brown K,Guldevall K,Saeed M,Pende D,Önfelt B,MacDonald AS,Davis DM
11-0149 was used in Flow cytometry/Cell sorting to study the impact of natural killer-dendritic cell interactions in Th1 immune responses and polarising Th2 immunity.
Mon Oct 01 00:00:00 EDT 2018
Isolation and characterization of stem cells from differentially degenerated human lumbar zygapophyseal articular cartilage.
Molecular medicine reports
Xiao L,Xu S,Wang X,Jin Z,Wang J,Yang B,Xu H
11-0149 was used in Flow cytometry/Cell sorting to show stem cells with multilineage differentiation potential and clonal properties were identified in human LZAC, and these characteristics were more prominent in mildly degenerated as compared with severely degenerated articular cartilage.
Sat Dec 01 00:00:00 EST 2018
BNIP3/Bcl-2-mediated apoptosis induced by cyclic tensile stretch in human cartilage endplate-derived stem cells.
Experimental and therapeutic medicine
Yuan C,Pu L,He Z,Wang J
11-0149-42 was used in Flow Cytometry to investigate the molecular mechanisms of cyclic stretch-induced apoptosis in human intervertebral disc cartilage endplate-derived stem cells (CESCs).
Mon Jan 01 00:00:00 EST 2018
Human umbilical cord-derived mesenchymal stem cells ameliorate the enteropathy of food allergies in mice.
Experimental and therapeutic medicine
Yan N,Xu J,Zhao C,Wu Y,Gao F,Li C,Zhou W,Xiao T,Zhou X,Shao Q,Xia S
11-0149-42 was used in Flow Cytometry to that CSFV (classical swine fever virus) infection reduces pyruvate levels while promotes lactate release in pigs and in PK-15 cells.
Sat Dec 01 00:00:00 EST 2018
Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway.
Nature communications
Tang-Huau TL,Gueguen P,Goudot C,Durand M,Bohec M,Baulande S,Pasquier B,Amigorena S,Segura E
11-0149 was used in Flow cytometry/Cell sorting to demonstrate that human monocyte-derived cells cross-present exclusively using a vacuolar pathway.
Mon Jul 02 00:00:00 EDT 2018
Human-induced pluripotent stem cell-derived macrophages and their immunological function in response to tuberculosis infection.
Stem cell research & therapy
Hong D,Ding J,Li O,He Q,Ke M,Zhu M,Liu L,Ou WB,He Y,Wu Y
11-0149 was used in Flow cytometry/Cell sorting to characterise human induced pluripotent stem cell-derived macrophages and their response to Bacillus Calmette-Guerin infection.
Mon Feb 26 00:00:00 EST 2018
Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages.
Nature communications
Yan J,Tie G,Wang S,Tutto A,DeMarco N,Khair L,Fazzio TG,Messina LM
11-0149 was used in Flow cytometry/Cell sorting to demonstrate for the first time that type 2 diabetes mellitus induces an haematopoietic stem cell-autonomous mechanism that causes impaired wound healing.
Tue Jan 02 00:00:00 EST 2018
Molecular signatures associated with tumor-specific immune response in melanoma patients treated with dendritic cell-based immunotherapy.
Oncotarget
García-Salum T,Villablanca A,Matthäus F,Tittarelli A,Baeza M,Pereda C,Gleisner MA,González FE,López MN,Hoheisel JD,Norgauer J,Gebicke-Haerter PJ,Salazar-Onfray F
11-0149 was used in Flow cytometry/Cell sorting to identify molecular markers associated with clinical outcome and gain a better understanding of clinically relevant immunological responses induced by anti-tumour dendritic cell-vaccines.
Fri Mar 30 00:00:00 EDT 2018
CCL3 and MMP-9 are induced by TL1A during death receptor 3 (TNFRSF25)-dependent osteoclast function and systemic bone loss.
Bone
Collins FL,Williams JO,Bloom AC,Singh RK,Jordan L,Stone MD,McCabe LR,Wang ECY,Williams AS
11-0149 was used in Flow cytometry/Cell sorting to show that the DR3/TL1A pathway enhances human osteoclast function through the modulation of CCL3 and MMP-9 expression.
Sat Apr 01 00:00:00 EDT 2017
A high-yield isolation and enrichment strategy for human lung microvascular endothelial cells.
Pulmonary circulation
Gaskill C,Majka SM
11-0149 was used in Flow cytometry/Cell sorting to describe a protocol to select large quantities of enriched primary human lung microvascular endothelial cells, free from mesenchymal contamination.
Wed Mar 01 00:00:00 EST 2017
Cytochrome P450s in human immune cells regulate IL-22 and c-Kit via an AHR feedback loop.
Scientific reports
Effner R,Hiller J,Eyerich S,Traidl-Hoffmann C,Brockow K,Triggiani M,Behrendt H,Schmidt-Weber CB,Buters JT
11-0149 was used in Flow cytometry/Cell sorting to study the interdependence of Cytochrome P4501 enzymes and aryl hydrocarbon receptor in human primary immune cells.
Thu Mar 09 00:00:00 EST 2017
Prostaglandin E2-mediated adenosinergic effects on CD14+ cells: Self-amplifying immunosuppression in cancer.
Oncoimmunology
Al-Taei S,Salimu J,Spary LK,Clayton A,Lester JF,Tabi Z
11-0149 was used in Flow cytometry/Cell sorting to show that CD73 expression can be induced by PGE2, cAMP or adenosine on human CD14+ cells.
Tue Jan 12 00:00:00 EST 2021
Tissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection.
European journal of immunology
Venkatasubramanian S,Tripathi D,Tucker T,Paidipally P,Cheekatla S,Welch E,Raghunath A,Jeffers A,Tvinnereim AR,Schechter ME,Andrade BB,Mackman N,Idell S,Vankayalapati R
11-0149 was used in Flow cytometry/Cell sorting to determine the role of tissue factor expressed by myeloid cells during Mycobacterium tuberculosis infection.
Mon Feb 01 00:00:00 EST 2016
Definitive Hematopoietic Multipotent Progenitor Cells Are Transiently Generated From Hemogenic Endothelial Cells in Human Pluripotent Stem Cells.
Journal of cellular physiology
Bai H,Liu Y,Xie Y,Hoyle DL,Brodsky RA,Cheng L,Cheng T,Wang ZZ
11-0149 was used in Flow cytometry/Cell sorting to demonstrate that CD34+CD31+CD144+ HEPs give rise to hematopoietic MPP cells via hemogenic endothelial cells that exist transiently.
Sun May 01 00:00:00 EDT 2016
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
Nature communications
Jacoby E,Nguyen SM,Fountaine TJ,Welp K,Gryder B,Qin H,Yang Y,Chien CD,Seif AE,Lei H,Song YK,Khan J,Lee DW,Mackall CL,Gardner RA,Jensen MC,Shern JF,Fry TJ
11-0149 was used in Flow cytometry/Cell sorting to study how CD19 CAR immune pressure induces a B-precursor acute lymphoblastic leukaemia lineage switch.
Wed Jul 27 00:00:00 EDT 2016
MIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia.
Stem cell reports
Yao Y,Deng Q,Song W,Zhang H,Li Y,Yang Y,Fan X,Liu M,Shang J,Sun C,Tang Y,Jin X,Liu H,Huang B,Zhou Y
11-0149 was used in Flow cytometry/Cell sorting to show MIF plays a role in regulating the differentiation fate of human cartilage endplate stem cells under hypoxia.
Tue Aug 09 00:00:00 EDT 2016
Involvement of Macrophages in the Pathogenesis of Familial Amyloid Polyneuropathy and Efficacy of Human iPS Cell-Derived Macrophages in Its Treatment.
PloS one
Suenaga G,Ikeda T,Komohara Y,Takamatsu K,Kakuma T,Tasaki M,Misumi Y,Ueda M,Ito T,Senju S,Ando Y
11-0149 was used in Flow cytometry/Cell sorting to evaluate abnormalities in heart tissue-resident macrophages in familial amyloid polyneuropathy.
Thu Jun 15 00:00:00 EDT 2017
The trajectory of the blood DNA methylome ageing rate is largely set before adulthood: evidence from two longitudinal studies.
Age (Dordrecht, Netherlands)
Kananen L,Marttila S,Nevalainen T,Kummola L,Junttila I,Mononen N,Kähönen M,Raitakari OT,Hervonen A,Jylhä M,Lehtimäki T,Hurme M,Jylhävä J
11-0149 was used in Flow cytometry/Cell sorting to demonstrate that the general level of δ-cAge-DNAmAge is fixed before adulthood and appears to be quite stationary thereafter.
Wed Jun 01 00:00:00 EDT 2016
Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3.
Blood
Haapaniemi EM,Kaustio M,Rajala HL,van Adrichem AJ,Kainulainen L,Glumoff V,Doffinger R,Kuusanmäki H,Heiskanen-Kosma T,Trotta L,Chiang S,Kulmala P,Eldfors S,Katainen R,Siitonen S,Karjalainen-Lindsberg ML,Kovanen PE,Otonkoski T,Porkka K,Heiskanen K,Hänninen A,Bryceson YT,Uusitalo-Seppälä R,Saarela J,Seppänen M,Mustjoki S,Kere J
11-0149 was used in Flow cytometry/Cell sorting to investigate phenotypes caused by activating STAT3 mutations, linking understanding of the STAT family of TFs and autoimmunity.
Thu Jan 22 00:00:00 EST 2015
Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3.
Blood
Haapaniemi EM,Kaustio M,Rajala HL,van Adrichem AJ,Kainulainen L,Glumoff V,Doffinger R,Kuusanmäki H,Heiskanen-Kosma T,Trotta L,Chiang S,Kulmala P,Eldfors S,Katainen R,Siitonen S,Karjalainen-Lindsberg ML,Kovanen PE,Otonkoski T,Porkka K,Heiskanen K,Hänninen A,Bryceson YT,Uusitalo-Seppälä R,Saarela J,Seppänen M,Mustjoki S,Kere J
11-0149 was used in Flow cytometry/Cell sorting to investigate phenotypes caused by activating STAT3 mutations, linking understanding of the STAT family of TFs and autoimmunity.
Thu Jan 22 00:00:00 EST 2015
Relationship between interleukin-1 type 1 and 2 receptor gene polymorphisms and the expression level of membrane-bound receptors.
Cellular & molecular immunology
Vasilyev FF,Silkov AN,Sennikov SV
11-0149 was used in Flow cytometry/Cell sorting to determine the relationship between interleukin-1 type 1 and type 2 receptor gene polymorphisms and the expression level of membrane-bound IL1-Rs.
Sun Mar 01 00:00:00 EST 2015
Correlation of low CD73 expression on synovial lymphocytes with reduced adenosine generation and higher disease severity in juvenile idiopathic arthritis.
Arthritis & rheumatology (Hoboken, N.J.)
Botta Gordon-Smith S,Ursu S,Eaton S,Moncrieffe H,Wedderburn LR
11-0149 was used in Flow cytometry/Cell sorting to compare the expression of CD73 on lymphocytes from patients with juvenile idiopathic arthritis to healthy control subjects.
Sun Feb 01 00:00:00 EST 2015
Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis.
Mediators of inflammation
Alshevskaya AA,Lopatnikova JA,Shkaruba NS,Chumasova OA,Sizikov AE,Karaulov AV,Kozlov VA,Sennikov SV
11-0149 was used in Flow cytometry/Cell sorting to study immune cell types and their differential expression of receptors to immunomodulatory cytokines in healthy and arthritic individuals.
Tue Jun 21 00:00:00 EDT 2016
Hyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells.
PLoS neglected tropical diseases
Katawa G,Layland LE,Debrah AY,von Horn C,Batsa L,Kwarteng A,Arriens S,W Taylor D,Specht S,Hoerauf A,Adjobimey T
11-0149 was used in Flow cytometry/Cell sorting to provide initial evidence that elevated frequencies of Th17 and Th2 cells form part of the immune network instigating the development of severe onchocerciasis.
Thu Jan 01 00:00:00 EST 2015
Clinical proteomics identifies urinary CD14 as a potential biomarker for diagnosis of stable coronary artery disease.
PloS one
Lee MY,Huang CH,Kuo CJ,Lin CL,Lai WT,Chiou SH
11-0149 was used in Flow cytometry/Cell sorting to investigate potential biomarkers for diagnosis of coronary artery disease using clinical proteomics.
Mon Jan 04 00:00:00 EST 2016
Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90+ study.
Age (Dordrecht, Netherlands)
Nevalainen T,Kananen L,Marttila S,Jylhä M,Hervonen A,Hurme M,Jylhävä J
11-0149 was used in Flow cytometry/Cell sorting to investigate gender differences in ageing-associated inflammation.
Sat Aug 01 00:00:00 EDT 2015
Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression.
BMC genomics
Marttila S,Kananen L,Häyrynen S,Jylhävä J,Nevalainen T,Hervonen A,Jylhä M,Nykter M,Hurme M
11-0149 was used in Flow cytometry/Cell sorting to investigate how ageing-associated DNA methylation changes at single-CpG-site resolution in blood leukocytes and ensure that the observed changes were not due to differences in the proportions of leukocytes.
Sat Mar 14 00:00:00 EDT 2015
Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny.
Oncotarget
Marttila S,Kananen L,Jylhävä J,Nevalainen T,Hervonen A,Jylhä M,Hurme M
11-0149 was used in Flow cytometry/Cell sorting to investigate whether epigenetic features contribute to heritability of lifespan.
Tue Oct 13 00:00:00 EDT 2015
Expansion of myeloid-derived suppressor cells in patients with acute coronary syndrome.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Wang YG,Xiong X,Chen ZY,Liu KL,Yang JH,Wen Q,Wu FQ,Hu XF,Peng YD,Wu JJ,Lian YT,Zhang WC,Cheng LX
11-0149 was used in Flow cytometry/Cell sorting to observe an increased frequency and suppressive function of MDSCs in ACS patients, a result that may provide insights into the mechanisms involved in ACS.
Thu Sep 10 00:00:00 EDT 2015
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression.
Science (New York, N.Y.)
Fairfax BP,Humburg P,Makino S,Naranbhai V,Wong D,Lau E,Jostins L,Plant K,Andrews R,McGee C,Knight JC
11-0149 was used in Flow cytometry/Cell sorting to show that applying pathophysiologically relevant immune stimuli assists the resolution of functional genetic variants.
Fri Mar 07 00:00:00 EST 2014
Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Koido S,Homma S,Okamoto M,Takakura K,Mori M,Yoshizaki S,Tsukinaga S,Odahara S,Koyama S,Imazu H,Uchiyama K,Kajihara M,Arakawa H,Misawa T,Toyama Y,Yanagisawa S,Ikegami M,Kan S,Hayashi K,Komita H,Kamata Y,Ito M,Ishidao T,Yusa S,Shimodaira S,Gong J,Sugiyama H,Ohkusa T,Tajiri H
11-0149 was used in Flow cytometry/Cell sorting to investigate the safety, clinical responses, and immune response following a novel combination therapy against pancreatic ductal adenocarcinoma.
Fri Aug 15 00:00:00 EDT 2014
Oroxylin A has therapeutic potential in acute myelogenous leukemia by dual effects targeting PPARγ and RXRα.
International journal of cancer
Hui H,Chen Y,Yang H,Zhao K,Wang Q,Zhao L,Wang X,Li Z,Lu N,Guo Q
11-0149 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which oroxylin A has therapeutic potential in acute myelogenous leukaemia treatment.
Sat Mar 01 00:00:00 EST 2014
VB-201, an oxidized phospholipid small molecule, inhibits CD14- and Toll-like receptor-2-dependent innate cell activation and constrains atherosclerosis.
Clinical and experimental immunology
Mendel I,Feige E,Yacov N,Salem Y,Levi I,Propheta-Meiran O,Shoham A,Ishai E,George J,Harats D,Breitbart E
11-0149-42 was used in Flow Cytometry to demonstrate that VB-201 inhibits Toll-like receptor (TLR) signalling restricted to TLR-2 and TLR-4 in human and mouse monocytes and dendritic cells.
Wed Jan 01 00:00:00 EST 2014
Delta-like 1-mediated Notch signaling enhances the in vitro conversion of human memory CD4 T cells into FOXP3-expressing regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Mota C,Nunes-Silva V,Pires AR,Matoso P,Victorino RM,Sousa AE,Caramalho I
11-0149 was used in Flow cytometry/Cell sorting to investigate novel strategies to generate in vitro-induced Tregs.
Mon Dec 15 00:00:00 EST 2014
Polymorphisms in the tumor necrosis factor receptor genes affect the expression levels of membrane-bound type I and type II receptors.
Mediators of inflammation
Sennikov SV,Vasilyev FF,Lopatnikova JA,Shkaruba NS,Silkov AN
11-0149 was used in Flow cytometry/Cell sorting to investigate the level of TNF receptors on various cells of the immune system and its association with gene polymorphism.
Mon Dec 15 00:00:00 EST 2014
Interactions between alveolar epithelial cells and neutrophils under pro-inflammatory conditions.
European clinical respiratory journal
von Schéele I,Larsson K,Palmberg L
11-0149 was used in Flow cytometry/Cell sorting to investigate communication between cells constituting the first line of defence under infection from chronic obstructive pulmonary disease.
Wed Nov 11 00:00:00 EST 2015
Quantitative reconstruction of leukocyte subsets using DNA methylation.
Genome biology
Accomando WP,Wiencke JK,Houseman EA,Nelson HH,Kelsey KT
11-0149 was used in Flow cytometry/Cell sorting to study how precise immune cell differential estimates can be reconstructed using only DNA rather than whole cells.
Wed Mar 05 00:00:00 EST 2014
Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty.
Aging cell
Jylhävä J,Nevalainen T,Marttila S,Jylhä M,Hervonen A,Hurme M
11-0149 was used in Flow cytometry/Cell sorting to characterise the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty.
Sat Jun 01 00:00:00 EDT 2013
The anti-idiotypic antibody 1F7 stimulates monocyte interleukin-10 production and induces endotoxin tolerance.
Journal of inflammation (London, England)
Davtyan TK,Poghosyan DA,Sukiasyan AG,Grant MD
11-0149 was used in Flow cytometry/Cell sorting to investigate the direct effects of the 1F7 mAb on peripheral blood mononuclear cells.
Fri Apr 05 00:00:00 EDT 2013
Optimized flow cytometry protocol for analysis of surface expression of interleukin-1 receptor types I and II.
Cytotechnology
Vasilyev FF,Lopatnikova JA,Sennikov SV
11-0149 was used in Flow cytometry/Cell sorting to analyse different cell subpopulations for the number of membrane-bound IL-1R molecules.
Tue Oct 01 00:00:00 EDT 2013
From macrophage interleukin-13 receptor to foam cell formation: mechanisms for αMβ2 integrin interference.
The Journal of biological chemistry
Yakubenko VP,Hsi LC,Cathcart MK,Bhattacharjee A
11-0149 was used in Flow cytometry/Cell sorting to investigate the molecular mechanisms that down-regulate CD36 expression and CD36-mediated foam cell formation after α(M)β(2) activation.
Fri Jan 25 00:00:00 EST 2013
Transcriptional analysis reveals gender-specific changes in the aging of the human immune system.
PloS one
Marttila S,Jylhävä J,Nevalainen T,Nykter M,Jylhä M,Hervonen A,Tserel L,Peterson P,Hurme M
11-0149 was used in Flow cytometry/Cell sorting to demonstrate that the effects of aging on the human immune system are significantly different in males and females.
Thu Jan 16 00:00:00 EST 2014
Peripheral monocyte functions and activation in patients with quiescent Crohn's disease.
PloS one
Schwarzmaier D,Foell D,Weinhage T,Varga G,Däbritz J
11-0149 was used in Flow cytometry/Cell sorting to investigate the phenotypic and functional features of peripheral blood monocytes in patients with quiescent Chron's disease.
Mon Dec 09 00:00:00 EST 2013
Adipocyte-derived soluble factor(s) inhibits early stages of B lymphopoiesis.
Journal of immunology (Baltimore, Md. : 1950)
Bilwani FA,Knight KL
11-0149 was used in Flow cytometry/Cell sorting to investigate the factors contributing to an observed age-related decline in B lymphopoiesis.
Thu Nov 01 00:00:00 EDT 2012
Double expression of CD34 and CD117 on bone marrow progenitors is a hallmark of the development of functional mast cell of Callithrix jacchus (common marmoset).
International immunology
Nunomura S,Shimada S,Kametani Y,Yamada Y,Yoshioka M,Suemizu H,Ozawa M,Itoh T,Kono A,Suzuki R,Tani K,Ando K,Yagita H,Ra C,Habu S,Satake M,Sasaki E
11-0149 was used in Flow cytometry/Cell sorting to examine the development of mast cells from haematopoietic progenitors of Callithrix jacchus, an experimental animal of nonhuman primates.
Sat Sep 01 00:00:00 EDT 2012
Synovial fluid from patients with early osteoarthritis modulates fibroblast-like synoviocyte responses to toll-like receptor 4 and toll-like receptor 2 ligands via soluble CD14.
Arthritis and rheumatism
Nair A,Kanda V,Bush-Joseph C,Verma N,Chubinskaya S,Mikecz K,Glant TT,Malfait AM,Crow MK,Spear GT,Finnegan A,Scanzello CR
11-0149 was used in Flow cytometry/Cell sorting to investigate whether a TLR-2- or TLR-4-stimulating factor in synovial fluid from patients with early knee osteoarthritis with meniscal injury could lead to inflammatory activation of synoviocytes.
Sun Jul 01 00:00:00 EDT 2012
Neutrophil paralysis in Plasmodium vivax malaria.
PLoS neglected tropical diseases
Leoratti FM,Trevelin SC,Cunha FQ,Rocha BC,Costa PA,Gravina HD,Tada MS,Pereira DB,Golenbock DT,Antonelli LR,Gazzinelli RT
11-0149 was used in Flow cytometry/Cell sorting to investigate the activation and function of neutrophils during acute episodes of Plasmodium vivax malaria.
Fri Sep 28 00:00:00 EDT 2012
Evidence for local dendritic cell activation in pulmonary sarcoidosis.
Respiratory research
Ten Berge B,Kleinjan A,Muskens F,Hammad H,Hoogsteden HC,Hendriks RW,Lambrecht BN,Van den Blink B
11-0149 was used in Flow cytometry/Cell sorting to determine whether, at sites of sarcoidosis, dendritic cells are involved in granuloma formation and maintenance.
Wed Apr 18 00:00:00 EDT 2012
CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950)
Landrigan A,Wong MT,Utz PJ
11-0149 was used in Flow cytometry/Cell sorting to study the ability of oligodeoxynucleotides to activate and polarise T cells.
Thu Sep 15 00:00:00 EDT 2011
Toll-like receptor expression in smokers with and without COPD.
Respiratory medicine
von Scheele I,Larsson K,Dahlén B,Billing B,Skedinger M,Lantz AS,Palmberg L
11-0149 was used in Flow cytometry/Cell sorting to study Toll-like receptor expression in smokers with and without chronic obstructive pulmonary disease.
Mon Aug 01 00:00:00 EDT 2011
MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation.
Nature immunology
Li T,Morgan MJ,Choksi S,Zhang Y,Kim YS,Liu ZG
11-0149 was used in Flow cytometry/Cell sorting to discover the effects of a reduction in expression of certain miRNAs on macrophage response and function.
Wed Sep 01 00:00:00 EDT 2010
Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages.
Respiratory research
Hoppstädter J,Diesel B,Zarbock R,Breinig T,Monz D,Koch M,Meyerhans A,Gortner L,Lehr CM,Huwer H,Kiemer AK
11-0149 was used in Flow cytometry/Cell sorting to study how human alveolar and lung interstitial macrophages may differ in cell reaction upon toll-like receptor activation.
Wed Sep 15 00:00:00 EDT 2010
Fenoterol, a beta(2)-adrenoceptor agonist, inhibits LPS-induced membrane-bound CD14, TLR4/CD14 complex, and inflammatory cytokines production through beta-arrestin-2 in THP-1 cell line.
Acta pharmacologica Sinica
Wang W,Xu M,Zhang YY,He B
11-0149 was used in Flow cytometry/Cell sorting to investigate the molecular mechanism and signalling pathway by which fenoterol produces anti-inflammatory effects.
Sun Nov 01 00:00:00 EDT 2009
Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression.
Cancer science
Zhang K,Guo QL,You QD,Yang Y,Zhang HW,Yang L,Gu HY,Qi Q,Tan Z,Wang X
11-0149 was used in Flow cytometry/Cell sorting to investigate the potential role of wogonin in the proliferation and differentiation of an acute promyelocytic leukaemia cell line.
Tue Apr 01 00:00:00 EDT 2008
Mycobacterium tuberculosis-induced gamma interferon production by natural killer cells requires cross talk with antigen-presenting cells involving Toll-like receptors 2 and 4 and the mannose receptor in tuberculous pleurisy.
Infection and immunity
Schierloh P,Yokobori N,Alemán M,Landoni V,Geffner L,Musella RM,Castagnino J,Baldini M,Abbate E,de la Barrera SS,Sasiain MC
11-0149 was used in Flow cytometry/Cell sorting to study how the interplay between M. tuberculosis and NK cells/APC triggering IFN-gamma may play a beneficial role in tuberculous pleurisy by helping to maintain a type 1 profile.
Thu Nov 01 00:00:00 EDT 2007
The mycobacterial 38-kilodalton glycolipoprotein antigen activates the mitogen-activated protein kinase pathway and release of proinflammatory cytokines through Toll-like receptors 2 and 4 in human monocytes.
Infection and immunity
Jung SB,Yang CS,Lee JS,Shin AR,Jung SS,Son JW,Harding CV,Kim HJ,Park JK,Paik TH,Song CH,Jo EK
11-0149 was used in Flow cytometry/Cell sorting to study how the 38-kDa glycolipoprotein induces the activation of the ERK1/2 and p38 MAPK pathways, which play a role in TNF-alpha/IL-6 expression during mycobacterial infection.
Mon May 01 00:00:00 EDT 2006
