Product References
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2024
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Myeloid and plasmacytoid dendritic cell combined vaccines loaded with heat-treated tumor cell lysates enhance antitumor activity in murine lung cancer.
Oncology letters
Chen H,Tan J,Li X,Li H,Wu W,Wu Y,Zhang J,Gu L
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon Sep 20 00:00:00 EDT 2021
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Journal for immunotherapy of cancer
Wang Z,Xu F,Hu J,Zhang H,Cui L,Lu W,He W,Wang X,Li M,Zhang H,Xiong W,Xie C,Liu Y,Zhou P,Liu J,Huang P,Qin XF,Xia X
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Journal for immunotherapy of cancer
Wang Z,Xu F,Hu J,Zhang H,Cui L,Lu W,He W,Wang X,Li M,Zhang H,Xiong W,Xie C,Liu Y,Zhou P,Liu J,Huang P,Qin XF,Xia X
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models.
Proceedings of the National Academy of Sciences of the United States of America
Tian M,McGovern K,Cheng HL,Waddicor P,Rieble L,Dao M,Chen Y,Kimble MT,Cantor E,Manfredonia N,Judson R,Chapdelaine-Williams A,Cain DW,Haynes BF,Alt FW
12-0401 was used in Flow cytometry/Cell sorting to develop a new approach to test a vaccine which circumvents B cell developmental blocks.
Tue Apr 07 00:00:00 EDT 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
Nature communications
Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Thu Aug 27 00:00:00 EDT 2020
Mesenchymal stromal cells induce distinct myeloid-derived suppressor cells in inflammation.
JCI insight
Lee HJ,Ko JH,Kim HJ,Jeong HJ,Oh JY
12-0401 was used in Flow cytometry/Cell sorting to reveal that suppression of prostaglandin E2 (PGE2) and HGF secretion in MSCs by siRNA transfection partially reversed the effects of MSCs on MDSC differentiation.
Thu Jun 18 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8+ T Cell Memory and Delayed Tumor Progression.
International journal of nanomedicine
Darling R,Senapati S,Christiansen J,Liu L,Ramer-Tait AE,Narasimhan B,Wannemuehler M
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon Dec 07 00:00:00 EST 2020
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Tue Aug 13 00:00:00 EDT 2019
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Tue Aug 13 00:00:00 EDT 2019
CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity.
Oncology reports
Li Y,Zhao C,Liu J,Lu Z,Lu M,Gu J,Liu R
12-0401 was used in Flow cytometry/Cell sorting to investigate whether CD1d expression on dendritic cells is capable of enhancing anti-tumour immunity, particularly T-cell related immunity.
Wed May 01 00:00:00 EDT 2019
Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins.
Nature communications
Serradell MC,Rupil LL,Martino RA,Prucca CG,Carranza PG,Saura A,Fernández EA,Gargantini PR,Tenaglia AH,Petiti JP,Tonelli RR,Reinoso-Vizcaino N,Echenique J,Berod L,Piaggio E,Bellier B,Sparwasser T,Klatzmann D,Luján HD
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon Jan 21 00:00:00 EST 2019
STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research
Moreira D,Adamus T,Zhao X,Su YL,Zhang Z,White SV,Swiderski P,Lu X,DePinho RA,Pal SK,Kortylewski M
12-0401 was used in Flow cytometry/Cell sorting to show a novel strategy combining STAT3 inhibition with Toll-like Receptor 9 (TLR9) stimulation to unleash immune response against prostate cancers regardless of the genetic background.
Sat Dec 01 00:00:00 EST 2018
Bryostatin-1 alleviates experimental multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America
Kornberg MD,Smith MD,Shirazi HA,Calabresi PA,Snyder SH,Kim PM
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Tue Feb 27 00:00:00 EST 2018
Exosomes Shuttle TREX1-Sensitive IFN-Stimulatory dsDNA from Irradiated Cancer Cells to DCs.
Cancer immunology research
Diamond JM,Vanpouille-Box C,Spada S,Rudqvist NP,Chapman JR,Ueberheide BM,Pilones KA,Sarfraz Y,Formenti SC,Demaria S
12-0401 was used in Flow cytometry/Cell sorting to showe that tumor-derived exosomes (TEX) produced by irradiated mouse breast cancer cells (RT-TEX) transfer dsDNA to dendritic cells(DCs) and stimulate DC upregulation of costimulatory molecules and STING-dependent activation of IFN-I.
Wed Aug 01 00:00:00 EDT 2018
Human-induced pluripotent stem cell-derived macrophages and their immunological function in response to tuberculosis infection.
Stem cell research & therapy
Hong D,Ding J,Li O,He Q,Ke M,Zhu M,Liu L,Ou WB,He Y,Wu Y
12-0401 was used in Flow cytometry/Cell sorting to characterise human induced pluripotent stem cell-derived macrophages and their response to Bacillus Calmette-Guérin infection.
Mon Feb 26 00:00:00 EST 2018
FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells.
Frontiers in immunology
Pan YG,Yu YL,Lin CC,Lanier LL,Chu CL
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression.
Journal of immunology (Baltimore, Md. : 1950)
Dolina JS,Cechova S,Rudy CK,Sung SJ,Tang WW,Lee J,Hahn YS,Le TH
12-0401 was used in Flow cytometry/Cell sorting to identify the functional role of collectrin in the liver.
Wed Mar 15 00:00:00 EDT 2017
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Oncoimmunology
Shen Y,Guo D,Weng L,Wang S,Ma Z,Yang Y,Wang P,Wang J,Cai Z
12-0401-82 was used in Flow Cytometry to reveal a novel mechanism for the tumour-derived exosome(TEX)-mediated education of dendritic cells.
Tue Jan 12 00:00:00 EST 2021
Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.
JCI insight
Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Thu Sep 21 00:00:00 EDT 2017
MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to food-grade synthetic amorphous silica.
Particle and fibre toxicology
Winkler HC,Kornprobst J,Wick P,von Moos LM,Trantakis I,Schraner EM,Bathke B,Hochrein H,Suter M,Naegeli H
12-0401 was used in Flow cytometry/Cell sorting to unexpectedly show that food-grade SAS particles are able to directly initiate the endosomal MyD88-dependent pathogen pattern recognition and signaling pathway in steady-state DCs.
Fri Jun 23 00:00:00 EDT 2017
Nuclear receptor expression atlas in BMDCs: Nr4a2 restricts immunogenicity of BMDCs and impedes EAE.
European journal of immunology
Saini A,Mahajan S,Gupta P
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes.
Journal of leukocyte biology
Lagassé HA,Anidi IU,Craig JM,Limjunyawong N,Poupore AK,Mitzner W,Scott AL
12-0401 was used in Flow cytometry/Cell sorting to investigate the mechanisms governing the nature and extent of malaria-associated lung injury.
Sun May 01 00:00:00 EDT 2016
G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way.
Journal of immunology (Baltimore, Md. : 1950)
Perobelli SM,Mercadante AC,Galvani RG,Gonçalves-Silva T,Alves AP,Pereira-Neves A,Benchimol M,Nóbrega A,Bonomo A
12-0401 was used in Flow cytometry/Cell sorting to study the role of incoming IL-10+ neutrophils from G-CSF-treated donor spleen in inhibiting acute graft-versus-host disease.
Tue Nov 01 00:00:00 EDT 2016
MIF Promotes Classical Activation and Conversion of Inflammatory Ly6C(high) Monocytes into TipDCs during Murine Toxoplasmosis.
Mediators of inflammation
Ruiz-Rosado Jde D,Olguín JE,Juárez-Avelar I,Saavedra R,Terrazas LI,Robledo-Avila FH,Vazquez-Mendoza A,Fernández J,Satoskar AR,Partida-Sánchez S,Rodriguez-Sosa M
12-0401 was used in Flow cytometry/Cell sorting to analyse the role of migration inhibitory factor in the maturation of CD11b(+) and CD8α (+) dendritic cells.
Fri Dec 30 00:00:00 EST 2016
Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS.
Human vaccines & immunotherapeutics
Xu X,Gao Y,Zhai Z,Zhang S,Shan F,Feng J
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
MyD88/CD40 Genetic Adjuvant Function in Cutaneous Atypical Antigen-Presenting Cells Contributes to DNA Vaccine Immunogenicity.
PloS one
Collinson-Pautz MR,Slawin KM,Levitt JM,Spencer DM
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Wed May 31 00:00:00 EDT 2017
D-Alanylation of Teichoic Acids and Loss of Poly-N-Acetyl Glucosamine in Staphylococcus aureus during Exponential Growth Phase Enhance IL-12 Production in Murine Dendritic Cells.
PloS one
Lund LD,Ingmer H,Frøkiær H
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Thu Jul 14 00:00:00 EDT 2016
Effects of interleukin-1 receptor-associated kinase 1 RNA interference in dendritic cells on inflammatory cytokine release and T-cell proliferation.
Molecular medicine reports
Gao Y,Xu X,Feng J,Ma Y,Zheng D,Meng Y,Shan F
12-0401-82 was used in Flow cytometry/Cell sorting to reduce the expression of interleukin-1 receptor-associated kinase 1 in dendritic cells by RNA interference.
Thu Dec 01 00:00:00 EST 2016
CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control.
Oncoimmunology
Veinotte L,Gebremeskel S,Johnston B
12-0401 was used in Flow cytometry/Cell sorting to study the co-stimulatory role of CXCR6/CXCL16 interactions in glycolipid-dependent invariant natural killer T (iNKT) cell activation and tumour control, showing that CXCL16-positive dendritic cells enhance iNKT cell-dependent IFNγ production and tumor control.
Wed Jun 01 00:00:00 EDT 2016
Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer.
Nature communications
Dubeykovskaya Z,Si Y,Chen X,Worthley DL,Renz BW,Urbanska AM,Hayakawa Y,Xu T,Westphalen CB,Dubeykovskiy A,Chen D,Friedman RA,Asfaha S,Nagar K,Tailor Y,Muthupalani S,Fox JG,Kitajewski J,Wang TC
12-0401 was used in Flow cytometry/Cell sorting to show that TFF2 is released by vagally modulated memory T cells to suppress the expansion of myeloid-derived suppressor cells through CXCR4.
Thu Feb 04 00:00:00 EST 2016
Cholera Toxin Promotes Th17 Cell Differentiation by Modulating Expression of Polarizing Cytokines and the Antigen-Presenting Potential of Dendritic Cells.
PloS one
Kang JO,Lee JB,Chang J
12-0401 was used in Flow cytometry/Cell sorting to determine how cholera toxin skews the differentiation of CD4 T cells to form IL-17-producing Th17 cells.
Tue Aug 08 00:00:00 EDT 2017
A novel regulatory macrophage induced by a helminth molecule instructs IL-10 in CD4+ T cells and protects against mucosal inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Ziegler T,Rausch S,Steinfelder S,Klotz C,Hepworth MR,Kühl AA,Burda PC,Lucius R,Hartmann S
12-0401 was used in Flow cytometry/Cell sorting to investigate the mechanism by which the helminth immunomodulator AvCystatin induces a novel regulatory macrophage able to protect against allergic mucosal inflammation in mice.
Sun Feb 15 00:00:00 EST 2015
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
Bifidobacterium longum CCM 7952 Promotes Epithelial Barrier Function and Prevents Acute DSS-Induced Colitis in Strictly Strain-Specific Manner.
PloS one
Srutkova D,Schwarzer M,Hudcovic T,Zakostelska Z,Drab V,Spanova A,Rittich B,Kozakova H,Schabussova I
12-0401 was used in Flow cytometry/Cell sorting to compare two Bifidobacterium longum ssp. longum strains for their capacity to prevent experimental colitis.
Tue May 03 00:00:00 EDT 2016
H9N2 influenza whole inactivated virus combined with polyethyleneimine strongly enhances mucosal and systemic immunity after intranasal immunization in mice.
Clinical and vaccine immunology : CVI
Qin T,Yin Y,Huang L,Yu Q,Yang Q
12-0401 was used in Flow cytometry/Cell sorting to investigate the immune activity of polyethyleneimine with H9N2 influenza whole inactivated virus, showing that it enhances mucosal and systemic immunity after intranasal immunization.
Wed Apr 01 00:00:00 EDT 2015
The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.
Nature immunology
Agudo J,Ruzo A,Tung N,Salmon H,Leboeuf M,Hashimoto D,Becker C,Garrett-Sinha LA,Baccarini A,Merad M,Brown BD
12-0401 was used in Flow cytometry/Cell sorting to identify the miR-126-VEGFR2 axis as an important regulator of the innate response that operates through multiscale control of pDCs.
Wed Jan 01 00:00:00 EST 2014
The glycosylated Rv1860 protein of Mycobacterium tuberculosis inhibits dendritic cell mediated TH1 and TH17 polarization of T cells and abrogates protective immunity conferred by BCG.
PLoS pathogens
Satchidanandam V,Kumar N,Jumani RS,Challu V,Elangovan S,Khan NA
12-0401 was used in Flow cytometry/Cell sorting to investigate the effect of BCG-TB1860 on both the adaptive and innate immune responses.
Sun Jun 01 00:00:00 EDT 2014
Roles of major histocompatibility complex class II in inducing protective immune responses to influenza vaccination.
Journal of virology
O E,Lee YT,Ko EJ,Kim KH,Lee YN,Song JM,Kwon YM,Kim MC,Perez DR,Kang SM
12-0401 was used in Immunocytochemistry to reveal that MHC-II molecules play multiple roles in inducing protective immunity to influenza vaccination.
Tue Jul 01 00:00:00 EDT 2014
Paclitaxel-exposed ovarian cancer cells induce cancer‑specific CD4+ T cells after doxorubicin exposure through regulation of MyD88 expression.
International journal of oncology
Kim JE,Jang MJ,Jin DH,Chung YH,Choi BS,Park GB,Kim YS,Kim S,Hur DY,Hung CF,Kim D
12-0401 was used in Flow cytometry/Cell sorting to study induction of cancer-specific CD4+ T cells by paclitaxel-exposed ovarian cancer cells after doxorubicin exposure through regulation of MyD88 expression.
Thu May 01 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
More efficient induction of antitumor T cell immunity by exosomes from CD40L gene-modified lung tumor cells.
Molecular medicine reports
Wang J,Wang L,Lin Z,Tao L,Chen M
12-0401 was used in Flow cytometry/Cell sorting to investigate more efficient methods for inducing anti-tumour T cell immunity against lung cancer.
Wed Jan 01 00:00:00 EST 2014
Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis.
The Journal of biological chemistry
Bhattacharya A,Parillon X,Zeng S,Han S,Eissa NT
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Fri Sep 19 00:00:00 EDT 2014
Synergic silencing of costimulatory molecules prevents cardiac allograft rejection.
Journal of translational medicine
Zhang X,Liu Y,Zhang G,Shi J,Zhang X,Zheng X,Jiang AT,Zhang ZX,Johnston N,Siu KS,Chen R,Lian D,Koos D,Quan D,Min WP
12-0401 was used in Flow cytometry/Cell sorting to demonstrate that the simultaneous silencing of CD40 and CD80 prevents allograft rejection.
Thu May 22 00:00:00 EDT 2014
Rhamnogalacturonan II is a Toll-like receptor 4 agonist that inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells.
Experimental & molecular medicine
Park SN,Noh KT,Jeong YI,Jung ID,Kang HK,Cha GS,Lee SJ,Seo JK,Kang DH,Hwang TH,Lee EK,Kwon B,Park YM
12-0401 was used in Flow cytometry/Cell sorting to evaluate the effectiveness of RG-II-stimulated BMDC vaccination on the induction of antitumor immunity, showing that it inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells.
Fri Feb 08 00:00:00 EST 2013
Protection of islet grafts through transforming growth factor-β-induced tolerogenic dendritic cells.
Diabetes
Thomas DC,Wong FS,Zaccone P,Green EA,Wållberg M
12-0401 was used in Flow cytometry/Cell sorting to investigate methods to achieve long-term β-islet graft tolerance for diabetes type 1, showing that islets can be protected through expression of TGF-β.
Sun Sep 01 00:00:00 EDT 2013
Inactivation of tumor-specific CD8⁺ CTLs by tumor-infiltrating tolerogenic dendritic cells.
Immunology and cell biology
Harimoto H,Shimizu M,Nakagawa Y,Nakatsuka K,Wakabayashi A,Sakamoto C,Takahashi H
12-0401 was used in Flow cytometry/Cell sorting to investigate cancer immunosurveillance failure caused by the inactivation of CD8+ cytotoxic T lymphocytes by tolerogenic dendritic cells.
Tue Oct 01 00:00:00 EDT 2013
Recipient myeloid-derived immunomodulatory cells induce PD-1 ligand-dependent donor CD4+Foxp3+ regulatory T cell proliferation and donor-recipient immune tolerance after murine nonmyeloablative bone marrow transplantation.
Journal of immunology (Baltimore, Md. : 1950)
van der Merwe M,Abdelsamed HA,Seth A,Ong T,Vogel P,Pillai AB
12-0401 was used in Flow cytometry/Cell sorting to investigate the specific mechanisms of immune tolerance following TLI/ATS conditioning, showing the induction of PD-1 ligand-dependent donor Treg proliferation and donor-recipient immune tolerance.
Sun Dec 01 00:00:00 EST 2013
B cell activating factor inhibition impairs bacterial immunity by reducing T cell-independent IgM secretion.
Infection and immunity
Jones DD,Jones M,DeIulio GA,Racine R,MacNamara KC,Winslow GM
12-0401 was used in Flow cytometry/Cell sorting to determine that BAFF signalling can directly regulate secretory processes.
Sun Dec 01 00:00:00 EST 2013
Ulmus davidiana var. japonica Nakai upregulates eosinophils and suppresses Th1 and Th17 cells in the small intestine.
PloS one
Lee HS,Jang MS,Kim JH,Hong CP,Lee EJ,Jeun EJ,Kim C,Kim EK,Ahn KS,Yang BG,Ahn KS,Jang YP,Ahn KS,Kim YM,Jang MH
12-0401 was used in Flow cytometry/Cell sorting to investigate the frequency and cytokine profile of the major immune cells in mice treated orally with UDE.
Sat Aug 02 00:00:00 EDT 2014
Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages.
Journal of leukocyte biology
Movita D,Kreefft K,Biesta P,van Oudenaren A,Leenen PJ,Janssen HL,Boonstra A
12-0401 was used in Flow cytometry/Cell sorting to observe that freshly isolated Kupffer cells are endocytic and show a relatively high basal ROS content.
Mon Oct 01 00:00:00 EDT 2012
MyD88 drives the IFN-β response to Lactobacillus acidophilus in dendritic cells through a mechanism involving IRF1, IRF3, and IRF7.
Journal of immunology (Baltimore, Md. : 1950)
Weiss G,Maaetoft-Udsen K,Stifter SA,Hertzog P,Goriely S,Thomsen AR,Paludan SR,Frøkiær H
12-0401 was used in Flow cytometry/Cell sorting to demonstrate that phagosomal processing of Lactobacillus acidophilus (a natural intestine inhabitant) in dendritic cells stimulates IFN-β production.
Sat Sep 15 00:00:00 EDT 2012
Toll-like receptor 9-dependent activation of bone marrow-derived dendritic cells by URA5 DNA from Cryptococcus neoformans.
Infection and immunity
Tanaka M,Ishii K,Nakamura Y,Miyazato A,Maki A,Abe Y,Miyasaka T,Yamamoto H,Akahori Y,Fue M,Takahashi Y,Kanno E,Maruyama R,Kawakami K
12-0401 was used in Flow cytometry/Cell sorting to elucidate the mechanisms underlying Toll-like receptor 9-mediated activation of innate immune responses by using the URA5 gene from Cryptococcus neoformans.
Wed Feb 01 00:00:00 EST 2012
Nocardia brasiliensis cell wall lipids modulate macrophage and dendritic responses that favor development of experimental actinomycetoma in BALB/c mice.
Infection and immunity
Trevino-Villarreal JH,Vera-Cabrera L,Valero-Guillén PL,Salinas-Carmona MC
12-0401 was used in Flow cytometry/Cell sorting to investigate the parthenogenesis of Nocardia brasiliensis infection, showing that N.brasiliensis cell wall lipids modulate macrophage and dendritic responses, leading to actinomycetoma.
Mon Oct 01 00:00:00 EDT 2012
Retinal astrocytes pretreated with NOD2 and TLR2 ligands activate uveitogenic T cells.
PloS one
Jiang G,Sun D,Kaplan HJ,Shao H
12-0401 was used in Flow cytometry/Cell sorting to investigate the activation of uveitogenic T cells via the pretreatment of retinal astrocytes with NOD2 and TLR2 ligands.
Tue Mar 19 00:00:00 EDT 2013
Retinal astrocytes pretreated with NOD2 and TLR2 ligands activate uveitogenic T cells.
PloS one
Jiang G,Sun D,Kaplan HJ,Shao H
12-0401 was used in Flow cytometry/Cell sorting to investigate the activation of uveitogenic T cells via the pretreatment of retinal astrocytes with NOD2 and TLR2 ligands.
Tue Mar 19 00:00:00 EDT 2013
Retinal astrocytes pretreated with NOD2 and TLR2 ligands activate uveitogenic T cells.
PloS one
Jiang G,Sun D,Kaplan HJ,Shao H
12-0401 was used in Flow cytometry/Cell sorting to investigate the activation of uveitogenic T cells via the pretreatment of retinal astrocytes with NOD2 and TLR2 ligands.
Tue Mar 19 00:00:00 EDT 2013
Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages.
Immunology
Buhtoiarov IN,Sondel PM,Wigginton JM,Buhtoiarova TN,Yanke EM,Mahvi DA,Rakhmilevich AL
12-0401 was used in Flow cytometry/Cell sorting to show that chemotherapy and anti-CD40 + CpG-ODN IT synergise in the induction of anti-tumour effects which are associated with the phenotypic repolarisation of tumour-associated Mφ.
Tue Feb 01 00:00:00 EST 2011
IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid.
International immunology
Yabu M,Shime H,Hara H,Saito T,Matsumoto M,Seya T,Akazawa T,Inoue N
12-0401 was used in Immunofluorescence to show lactic acid functions as an inflammatory mediator that activates IL-23-dependent and -independent pathways to promote chronic inflammation in tumour microenvironments.
Sat Jan 01 00:00:00 EST 2011
Expression of the Mycobacterium tuberculosis PPE37 protein in Mycobacterium smegmatis induces low tumour necrosis factor alpha and interleukin 6 production in murine macrophages.
Journal of medical microbiology
Daim S,Kawamura I,Tsuchiya K,Hara H,Kurenuma T,Shen Y,Dewamitta SR,Sakai S,Nomura T,Qu H,Mitsuyama M
12-0401 was used in Flow cytometry/Cell sorting to suggest a potential role of PPE37 in interfering with the pro-inflammatory cytokine response of infected macrophages.
Sun May 01 00:00:00 EDT 2011
TLR4 promotes B cell maturation: independence and cooperation with B lymphocyte-activating factor.
Journal of immunology (Baltimore, Md. : 1950)
Hayashi EA,Granato A,Paiva LS,Bertho AL,Bellio M,Nobrega A
12-0401 was used in Flow cytometry/Cell sorting to perform an extensive study of cell surface markers and functional properties of B cells matured in vitro with LPS.
Sat May 01 00:00:00 EDT 2010
A method for generation of bone marrow-derived macrophages from cryopreserved mouse bone marrow cells.
PloS one
Marim FM,Silveira TN,Lima DS,Zamboni DS
12-0401 was used in Flow cytometry/Cell sorting to present a method for the easy generation of bone marrow-derived macrophages from frozen bone marrow cells.
Fri Dec 17 00:00:00 EST 2010
Distinct roles for MyD88 and Toll-like receptor 2 during Leishmania braziliensis infection in mice.
Infection and immunity
Vargas-Inchaustegui DA,Tai W,Xin L,Hogg AE,Corry DB,Soong L
12-0401 was used in Flow cytometry/Cell sorting to investigate whether TLRs are involved in L. braziliensis-mediated dendritic cell activation, showing distinct roles for MyD88 and TLR2 in infection.
Wed Jul 01 00:00:00 EDT 2009
Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.
Nature immunology
Lee SW,Park Y,So T,Kwon BS,Cheroutre H,Mittler RS,Croft M
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2008
Dynamics of lung macrophage activation in response to helminth infection.
Journal of leukocyte biology
Siracusa MC,Reece JJ,Urban JF,Scott AL
Published figure using CD40 monoclonal antibody (Product # 12-0401-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2008
IL-7 specifies B cell fate at the common lymphoid progenitor to pre-proB transition stage by maintaining early B cell factor expression.
Journal of immunology (Baltimore, Md. : 1950)
Kikuchi K,Kasai H,Watanabe A,Lai AY,Kondo M
12-0401 was used in Flow cytometry/Cell sorting to investigate when IL-7 stimulation is necessary in hemato-/lymphopoiesis in adult mice, showing that IL-7 specifies B cell fate at the common lymphoid progenitor to pre-proB transition stage by maintaining early B cell factor expression.
Tue Jul 01 00:00:00 EDT 2008
Leishmania braziliensis infection induces dendritic cell activation, ISG15 transcription, and the generation of protective immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Vargas-Inchaustegui DA,Xin L,Soong L
12-0401 was used in Flow cytometry/Cell sorting to investigate whether Leishmania braziliensis infection efficiently triggers innate responses in dendritic cells and the subsequent adaptive immune responses for parasite clearance.
Sun Jun 01 00:00:00 EDT 2008
Characterization of fibroblasts responsible for cartilage destruction in arthritis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Treese C,Mittag A,Lange F,Tarnok A,Loesche A,Emmrich F,Lehmann J,Sack U
12-0401 was used in Flow cytometry/Cell sorting to show that LS48 is an excellent tool to gain a deeper understanding of synovial fibroblasts in rheumatoid arthritis.
Tue Apr 01 00:00:00 EDT 2008
Down-regulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes.
Molecular immunology
Xin L,Li K,Soong L
12-0401 was used in Flow cytometry/Cell sorting to suggest that La parasites, especially in their intracellular forms, have evolved unique strategies to actively down-regulate early innate signalling events.
Tue Jul 01 00:00:00 EDT 2008
