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Invitrogen
CD132 Monoclonal Antibody (TUGh4), PE, eBioscience™
Product Details
12-1329-42
Product Specifications
Species Reactivity
Human
Host/Isotype
Rat
/ IgG2b, lambda
Recommended Isotype Control
Class
Monoclonal
Type
Antibody
Clone
TUGh4
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
5 µL/Test
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 0.2% BSA
Contains
0.09% sodium azide
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10733266
Product Specific Information
Description: This TUGh4 monoclonal antibody reacts with human CD132, the common gamma chain (gamma c) shared by the IL-2, IL-4, IL-7, IL-9, and IL-15 receptors. This approximately 65 kDa receptor component is expressed on T and B lymphocytes, NK cells, monocytes, and granulocytes. CD132 is involved in intracellular signal transduction by associating with effector molecules within the cytoplasm. Mutations in the human gamma chain gene result in X-linked severe combined immunodeficiency (XSCID), a disease characterized by T cell deficiency leading to impairment of cell-mediated and humoral immunity.
Applications Reported: This TUGh4 antibody has been reported for use in flow cytometric analysis.
Applications Tested: This TUGh4 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
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Bioinformatics
Protein Aliases: CD132; CD132 antigen; common cytokine receptor gamma chain; Cytokine receptor common subunit gamma; gammaC; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL2R gamma; interleukin 2 receptor, gamma; Interleukin-2 receptor subunit gamma; p64
Gene Aliases: CD132; CIDX; IL-2RG; IL2RG; IMD4; P64; SCIDX; SCIDX1
UniProt ID: (Human) P31785
Entrez Gene ID: (Human) 3561
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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