Product References
Germline Neurofibromin 1 mutation enhances the anti-tumour immune response and decreases juvenile myelomonocytic leukaemia tumourigenicity.
British journal of haematology
Wang W,Li X,Qin X,Miao Y,Zhang Y,Li S,Yao R,Yang Y,Yu L,Zhu H,Song L,Mao S,Wang X,Chen J,Feng H,Li Y
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Sat Jul 01 00:00:00 EDT 2023
Single-cell sequencing of ascites fluid illustrates heterogeneity and therapy-induced evolution during gastric cancer peritoneal metastasis.
Nature communications
Huang XZ,Pang MJ,Li JY,Chen HY,Sun JX,Song YX,Ni HJ,Ye SY,Bai S,Li TH,Wang XY,Lu JY,Yang JJ,Sun X,Mills JC,Miao ZF,Wang ZN
12-1639-42 was used in Flow cytometry/Cell sorting to describe different cell developmental lineage trajectories in the peritoneal ecosystem and provide evidence to better understand the mechanism of GCPM, aiding exploration of effective target strategies for GCPM therapy.
Tue Feb 14 00:00:00 EST 2023
SARS-CoV-2 Delta (B.1.617.2) variant replicates and induces syncytia formation in human induced pluripotent stem cell-derived macrophages.
PeerJ
Thaweerattanasinp T,Wanitchang A,Saenboonrueng J,Srisutthisamphan K,Wanasen N,Sungsuwan S,Jongkaewwattana A,Chailangkarn T
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Thu Mar 09 00:00:00 EST 2023
A positive feedback loop: RAD18-YAP-TGF-β between triple-negative breast cancer and macrophages regulates cancer stemness and progression.
Cell death discovery
Yan X,He Y,Yang S,Zeng T,Hua Y,Bao S,Yang F,Duan N,Sun C,Liang Y,Fu Z,Huang X,Li W,Yin Y
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Tue Apr 12 00:00:00 EDT 2022
M2-like tumor-associated macrophages transmit exosomal miR-27b-3p and maintain glioblastoma stem-like cell properties.
Cell death discovery
Zhao G,Ding L,Yu H,Wang W,Wang H,Hu Y,Qin L,Deng G,Xie B,Li G,Qi L
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Thu Aug 04 00:00:00 EDT 2022
M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway.
Cell death & disease
Jiang H,Zhou L,Shen N,Ning X,Wu D,Jiang K,Huang X
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Thu Feb 24 00:00:00 EST 2022
M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway.
Cell death & disease
Jiang H,Zhou L,Shen N,Ning X,Wu D,Jiang K,Huang X
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Thu Feb 24 00:00:00 EST 2022
TcpC Inhibits M1 but Promotes M2 Macrophage Polarization via Regulation of the MAPK/NF-κB and Akt/STAT6 Pathways in Urinary Tract Infection.
Cells
Fang J,Ou Q,Wu B,Li S,Wu M,Qiu J,Cen N,Hu K,Che Y,Ma Y,Pan J
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Sun Aug 28 00:00:00 EDT 2022
PTX3 mediates the infiltration, migration, and inflammation-resolving-polarization of macrophages in glioblastoma.
CNS neuroscience & therapeutics
Zhang H,Wang Y,Zhao Y,Liu T,Wang Z,Zhang N,Dai Z,Wu W,Cao H,Feng S,Zhang L,Cheng Q,Liu Z
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Use of Single Cell Transcriptomic Techniques to Study the Role of High-Risk Human Papillomavirus Infection in Cervical Cancer.
Frontiers in immunology
Meng L,Chen S,Shi G,He S,Wang Z,Shen J,Wang J,Sooranna SR,Zhao J,Song J
12-1639-42 was used in Immunohistochemistry (Frozen) to provide a basis for the development of a rational post-operative follow-up program and the development of an appropriate treatment plan for patients with cervical cancer.
Fri Jul 01 00:00:00 EDT 2022
Pulmonary transplantation of alpha-1 antitrypsin (AAT)-transgenic macrophages provides a source of functional human AAT in vivo.
Gene therapy
Janosz E,Hetzel M,Spielmann H,Tumpara S,Rossdam C,Schwabbauer M,Kloos D,von Kaisenberg C,Schambach A,Buettner FFR,Janciauskiene S,Lachmann N,Moritz T
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Wed Sep 01 00:00:00 EDT 2021
Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients.
Cells
Higham A,Baker JM,Jackson N,Shah R,Lea S,Singh D
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Tue Dec 21 00:00:00 EST 2021
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway.
EMBO molecular medicine
Wilcz-Villega E,Carter E,Ironside A,Xu R,Mataloni I,Holdsworth J,Jones W,Moreno Béjar R,Uhlik L,Bentham RB,Godinho SA,Dalli J,Grose R,Szabadkai G,Jones L,Hodivala-Dilke K,Bianchi K
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Fri Feb 07 00:00:00 EST 2020
Extracorporeal Hemadsorption versus Glucocorticoids during Cardiopulmonary Bypass: A Prospective, Randomized, Controlled Trial.
Cardiovascular therapeutics
Taleska Stupica G,Sostaric M,Bozhinovska M,Rupert L,Bosnic Z,Jerin A,Ihan A,Klokocovnik T,Podbregar M
12-1639 was used in Flow cytometry/Cell sorting to compare intraoperative hemadsorption and methylprednisolone, with usual care, during complex cardiac surgery on CPB, for inflammatory responses, hemodynamics, and perioperative course.
Mon Jul 06 00:00:00 EDT 2020
Extracorporeal Hemadsorption versus Glucocorticoids during Cardiopulmonary Bypass: A Prospective, Randomized, Controlled Trial.
Cardiovascular therapeutics
Taleska Stupica G,Sostaric M,Bozhinovska M,Rupert L,Bosnic Z,Jerin A,Ihan A,Klokocovnik T,Podbregar M
12-1639 was used in Flow cytometry/Cell sorting to compare intraoperative hemadsorption and methylprednisolone, with usual care, during complex cardiac surgery on CPB, for inflammatory responses, hemodynamics, and perioperative course.
Mon Jul 06 00:00:00 EDT 2020
Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.
Cells
Haake K,Neehus AL,Buchegger T,Kühnel MP,Blank P,Philipp F,Oleaga-Quintas C,Schulz A,Grimley M,Goethe R,Jonigk D,Kalinke U,Boisson-Dupuis S,Casanova JL,Bustamante J,Lachmann N
12-1639 was used in Flow cytometry/Cell sorting to report a disease modeling platform to study the role of macrophages in patients with inborn errors of IFN-γ immunity.
Wed Feb 19 00:00:00 EST 2020
Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.
Cells
Haake K,Neehus AL,Buchegger T,Kühnel MP,Blank P,Philipp F,Oleaga-Quintas C,Schulz A,Grimley M,Goethe R,Jonigk D,Kalinke U,Boisson-Dupuis S,Casanova JL,Bustamante J,Lachmann N
12-1639 was used in Flow cytometry/Cell sorting to report a disease modeling platform to study the role of macrophages in patients with inborn errors of IFN-γ immunity.
Wed Feb 19 00:00:00 EST 2020
Nanotopographical Coatings Induce an Early Phenotype-Specific Response of Primary Material-Resident M1 and M2 Macrophages.
Materials (Basel, Switzerland)
Schmitz T,Jannasch M,Weigel T,Moseke C,Gbureck U,Groll J,Walles H,Hansmann J
12-1639-42 was used in Flow Cytometry to investigate the influence of tubular TiO2 and fractal TiN nanostructures on primary human macrophages with M1 or M2-phenotype.
Wed Mar 04 00:00:00 EST 2020
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Cell death & disease
Huang R,Wang S,Wang N,Zheng Y,Zhou J,Yang B,Wang X,Zhang J,Guo L,Wang S,Chen Z,Wang Z,Xiang S
12-1639 was used in Flow cytometry/Cell sorting to demonstrate that TAMs-secreted CCL5 can significantly promote the migration, invasion, epithelial-mesenchymal transition (EMT) of prostate cancer cells as well as the self-renewal of PCSCs in vitro.
Thu Apr 16 00:00:00 EDT 2020
M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer.
Cancer research
Lan J,Sun L,Xu F,Liu L,Hu F,Song D,Hou Z,Wu W,Luo X,Wang J,Yuan X,Hu J,Wang G
12-1639 was used in Flow cytometry/Cell sorting to demonstrate that M2 macrophage-regulated colorectal cancer cells migration and invasion is dependent upon M2 macrophage-derived exosomes.
Tue Jan 01 00:00:00 EST 2019
Recruitment of monocytes and epigenetic silencing of intratumoral CYP7B1 primarily contribute to the accumulation of 27-hydroxycholesterol in breast cancer.
American journal of cancer research
Shi SZ,Lee EJ,Lin YJ,Chen L,Zheng HY,He XQ,Peng JY,Noonepalle SK,Shull AY,Pei FC,Deng LB,Tian XL,Deng KY,Shi H,Xin HB
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Tue Sep 29 00:00:00 EDT 2020
XIAOPI Formula Inhibits Breast Cancer Stem Cells via Suppressing Tumor-Associated Macrophages/C-X-C Motif Chemokine Ligand 1 Pathway.
Frontiers in pharmacology
Wang S,Liu X,Huang R,Zheng Y,Wang N,Yang B,Situ H,Lin Y,Wang Z
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Chromatin Binding of c-REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites.
Frontiers in immunology
Unger A,Finkernagel F,Hoffmann N,Neuhaus F,Joos B,Nist A,Stiewe T,Visekruna A,Wagner U,Reinartz S,Müller-Brüsselbach S,Müller R,Adhikary T
Wed Nov 20 00:00:00 EST 2019
TIM‑4 blockade of KCs combined with exogenous TGF‑β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts.
International journal of molecular medicine
Wu H,Xu X,Li J,Gong J,Li M
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2018
Biochanin a Enhances the Defense Against Salmonella enterica Infection Through AMPK/ULK1/mTOR-Mediated Autophagy and Extracellular Traps and Reversing SPI-1-Dependent Macrophage (MΦ) M2 Polarization.
Frontiers in cellular and infection microbiology
Zhao X,Tang X,Guo N,An Y,Chen X,Shi C,Wang C,Li Y,Li S,Xu H,Liu M,Wang Y,Yu L
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Fri Aug 30 00:00:00 EDT 2019
NF-κB/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification.
JCI insight
Barruet E,Morales BM,Cain CJ,Ton AN,Wentworth KL,Chan TV,Moody TA,Haks MC,Ottenhoff TH,Hellman J,Nakamura MC,Hsiao EC
12-1639 was used in Flow cytometry/Cell sorting to examine the potential link between bone morphogenetic proteins and inflammation in patients with fibrodysplasia ossificans progressiva.
Thu Nov 15 00:00:00 EST 2018
Exosomal transfer of mitochondria from airway myeloid-derived regulatory cells to T cells.
Redox biology
Hough KP,Trevor JL,Strenkowski JG,Wang Y,Chacko BK,Tousif S,Chanda D,Steele C,Antony VB,Dokland T,Ouyang X,Zhang J,Duncan SR,Thannickal VJ,Darley-Usmar VM,Deshane JS
12-1639 was used in Flow cytometry/Cell sorting to support a potential novel mechanism of cell-cell communication involving exosomal transfer of mitochondria and the bioenergetic and/or redox regulation of target cells.
Sat Sep 01 00:00:00 EDT 2018
In vitro chemotaxis and tissue remodeling assays quantitatively characterize foreign body reaction.
ALTEX
Jannasch M,Weigel T,Engelhardt L,Wiezoreck J,Gaetzner S,Walles H,Schmitz T,Hansmann J
12-1639 was used in Flow cytometry/Cell sorting to investigate the material dependency of fibroblast chemotaxis and tissue remodelling mediated by material-resident macrophages.
Tue Oct 10 00:00:00 EDT 2017
Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system.
Journal of neurovirology
Garcia-Mesa Y,Jay TR,Checkley MA,Luttge B,Dobrowolski C,Valadkhan S,Landreth GE,Karn J,Alvarez-Carbonell D
12-1639 was used in Flow cytometry/Cell sorting to show how the immortalization of primary microglia can provide a platform upon which to study HIV regulation in the central nervous system.
Wed Feb 01 00:00:00 EST 2017
Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system.
Journal of neurovirology
Garcia-Mesa Y,Jay TR,Checkley MA,Luttge B,Dobrowolski C,Valadkhan S,Landreth GE,Karn J,Alvarez-Carbonell D
12-1639 was used in Flow cytometry/Cell sorting to show how the immortalization of primary microglia can provide a platform upon which to study HIV regulation in the central nervous system.
Wed Feb 01 00:00:00 EST 2017
Alternatively activated macrophages derived from THP-1 cells promote the fibrogenic activities of human dermal fibroblasts.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Zhu Z,Ding J,Ma Z,Iwashina T,Tredget EE
Published figure using CD163 monoclonal antibody (Product # 12-1639-42) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors.
Molecular metabolism
Keuper M,Sachs S,Walheim E,Berti L,Raedle B,Tews D,Fischer-Posovszky P,Wabitsch M,Hrabě de Angelis M,Kastenmüller G,Tschöp MH,Jastroch M,Staiger H,Hofmann SM
12-1639 was used in Flow cytometry/Cell sorting to delineate how human macrophages may affect the energy metabolism of white adipocytes.
Sun Oct 01 00:00:00 EDT 2017
A comparative multi-parametric in vitro model identifies the power of test conditions to predict the fibrotic tendency of a biomaterial.
Scientific reports
Jannasch M,Gaetzner S,Weigel T,Walles H,Schmitz T,Hansmann J
12-1639 was used in Flow cytometry/Cell sorting to show that biomaterial ranking obtained under native plasma test conditions showed a high predictive accuracy compared to in vivo assessments.
Wed May 10 00:00:00 EDT 2017
MicroRNA-720 suppresses M2 macrophage polarization by targeting GATA3.
Bioscience reports
Zhong Y,Yi C
12-1639 was used in Flow cytometry/Cell sorting to investigate the role of miR-720 in tumour-associated macrophages (TAMs), showing that overexpression of miR-720 leads to suppression of M2 macrophage polarization by targeting GATA3.
Mon Aug 01 00:00:00 EDT 2016
An in vitro model of granuloma-like cell aggregates substantiates early host immune responses against Mycobacterium massiliense infection.
Biology open
Je S,Quan H,Na Y,Cho SN,Kim BJ,Seok SH
12-1639 was used in Flow cytometry/Cell sorting to study the interaction between host cells and Mycobacterium massiliense.
Mon Aug 15 00:00:00 EDT 2016
A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome.
Genome biology
Reinartz S,Finkernagel F,Adhikary T,Rohnalter V,Schumann T,Schober Y,Nockher WA,Nist A,Stiewe T,Jansen JM,Wagner U,Müller-Brüsselbach S,Müller R
12-1639 was used in Flow cytometry/Cell sorting to establish a signaling network operating in the ovarian cancer microenvironment with previously unidentified pathways and clinically relevant components.
Mon May 23 00:00:00 EDT 2016
CD64-directed microtubule associated protein tau kills leukemic blasts ex vivo.
Oncotarget
Mladenov R,Hristodorov D,Cremer C,Gresch G,Grieger E,Schenke L,Klose D,Amoury M,Woitok M,Jost E,Brümmendorf TH,Fendel R,Fischer R,Stein C,Thepen T,Barth S
12-1639 was used in Flow cytometry/Cell sorting to investigate how leukaemia may be treated by CD64-directed MAP tau.
Tue Oct 11 00:00:00 EDT 2016
Brugia malayi microfilariae induce a regulatory monocyte/macrophage phenotype that suppresses innate and adaptive immune responses.
PLoS neglected tropical diseases
O'Regan NL,Steinfelder S,Venugopal G,Rao GB,Lucius R,Srikantam A,Hartmann S
12-1639 was used in Flow cytometry/Cell sorting to show that monocytes stimulated with Brugia malayi microfilarial lysate develop a defined regulatory phenotype.
Wed Oct 01 00:00:00 EDT 2014
Haemophilus ducreyi-induced interleukin-10 promotes a mixed M1 and M2 activation program in human macrophages.
Infection and immunity
Li W,Katz BP,Spinola SM
12-1639 was used in Flow cytometry/Cell sorting to investigate the contribution of IL-10-modulated macrophage polarisation to H. ducreyi clearance during human infection.
Sat Dec 01 00:00:00 EST 2012
Artificial extracellular matrices composed of collagen I and high sulfated hyaluronan modulate monocyte to macrophage differentiation under conditions of sterile inflammation.
Biomatter
Kajahn J,Franz S,Rueckert E,Forstreuter I,Hintze V,Moeller S,Simon JC
12-1639 was used in Flow cytometry/Cell sorting to characterise the immunomodulating capacities of artifcial extracellular matrices and identify matrices that may benefit healing of biomaterials.
Thu Mar 20 00:00:00 EDT 2014
A prominent role for DC-SIGN+ dendritic cells in initiation and dissemination of measles virus infection in non-human primates.
PloS one
Mesman AW,de Vries RD,McQuaid S,Duprex WP,de Swart RL,Geijtenbeek TB
12-1639 was used in Flow cytometry/Cell sorting to identify DC-SIGN(hi) dendritic cells as the first target cells in the lungs for the measles virus in vivo.
Tue Jun 11 00:00:00 EDT 2013
Interleukin-25 fails to activate STAT6 and induce alternatively activated macrophages.
Immunology
Stolfi C,Caruso R,Franzè E,Sarra M,De Nitto D,Rizzo A,Pallone F,Monteleone G
Sat Jan 01 00:00:00 EST 2011
Interleukin-25 fails to activate STAT6 and induce alternatively activated macrophages.
Immunology
Stolfi C,Caruso R,Franzè E,Sarra M,De Nitto D,Rizzo A,Pallone F,Monteleone G
Sat Jan 01 00:00:00 EST 2011
