Product References
Glial cell line-derived neurotrophic factor increases matrix metallopeptidase 9 and 14 expression in microglia and promotes microglia-mediated glioma progression.
Journal of neuroscience research
Huang Y,Zhang B,Haneke H,Haage V,Lubas M,Yuan Y,Xia P,Motta E,Nanvuma C,Dzaye O,Hu F,Kettenmann H
Published figure using CD282 (TLR2) monoclonal antibody (Product # 12-9021-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Genomic and epigenomic adaptation in SP-R210 (Myo18A) isoform-deficient macrophages.
Immunobiology
Yau E,Chen Y,Song C,Webb J,Carillo M,Kawasawa YI,Tang Z,Takahashi Y,Umstead TM,Dovat S,Chroneos ZC
12-9021-82 was used in Flow Cytometry to suggest that the inflammatory differences seen in SP-R210L-deficient macrophages are a result of transcriptional differences that are mediated by epigenetic changes brought about by differential expression of the SP-R210 isoforms.
Mon Nov 01 00:00:00 EDT 2021
Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases.
iScience
Xu Y,Liu E,Xie X,Wang J,Zheng H,Ju Y,Chen L,Li C,Zhou X,Li Z,Li X,Meng S
12-9021-82 was used in Flow cytometry/Cell sorting to show that gp96 immunization restricted antibody-induced and Th-induced autoimmune diseases by integrating Treg expansion and activation, indicating its potential clinical usefulness against autoimmune diseases.
Fri Dec 17 00:00:00 EST 2021
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis.
Nature communications
Ramakrishna C,Kujawski M,Chu H,Li L,Mazmanian SK,Cantin EM
12-9021 was used in Flow cytometry/Cell sorting to study polysaccharide A as an immunomodulatory symbiosis factor whcih coordinates anti-inflammatory responses during viral infections.
Tue May 14 00:00:00 EDT 2019
Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis.
Nature communications
Ramakrishna C,Kujawski M,Chu H,Li L,Mazmanian SK,Cantin EM
12-9021 was used in Flow cytometry/Cell sorting to study polysaccharide A as an immunomodulatory symbiosis factor whcih coordinates anti-inflammatory responses during viral infections.
Tue May 14 00:00:00 EDT 2019
Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells.
Frontiers in pharmacology
Li M,Gao J,Tang Y,Liu M,Wu S,Qu K,Long X,Li H,Liu M,Liu Y,Yuan J,Mao L,Liu Y,Zheng X,Wang E,Wang J,Yang Y
Published figure using CD282 (TLR2) monoclonal antibody (Product # 12-9021-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
TLR2-/- Mice Display Increased Clearance of Dermatophyte Trichophyton mentagrophytes in the Setting of Hyperglycemia.
Frontiers in cellular and infection microbiology
Almeida DF,Fraga-Silva TF,Santos AR,Finato AC,Marchetti CM,Golim MA,Lara VS,Arruda MS,Venturini J
12-9021 was used in Flow cytometry/Cell sorting to demonstrate that TLR2 diminishes the development of adaptive immune responses during experimental deep dermatophytosis and, in a diabetic scenario, acts to intensify a non-protective inflammatory response.
Mon Sep 18 00:00:00 EDT 2017
Immunosuppression, peripheral inflammation and invasive infection from endogenous gut microbiota activate retinal microglia in mouse models.
Microbiology and immunology
Maneu V,Noailles A,Gómez-Vicente V,Carpena N,Cuenca N,Gil ML,Gozalbo D
12-9021 was used in Flow cytometry/Cell sorting to determine whether non-ocular conditions could lead to the activation of retinal microglia.
Thu Sep 01 00:00:00 EDT 2016
Porphyromonas gingivalis gingipains selectively reduce CD14 expression, leading to macrophage hyporesponsiveness to bacterial infection.
Journal of innate immunity
Wilensky A,Tzach-Nahman R,Potempa J,Shapira L,Nussbaum G
12-9021 was used in Flow cytometry/Cell sorting to study how porphyromonas gingivalis gingipains can reduce CD14 expression without affecting expression of the bacterial-sensing TLRs.
Mon Dec 21 00:00:00 EST 2015
CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.
The Journal of clinical investigation
Lionakis MS,Swamydas M,Fischer BG,Plantinga TS,Johnson MD,Jaeger M,Green NM,Masedunskas A,Weigert R,Mikelis C,Wan W,Lee CC,Lim JK,Rivollier A,Yang JC,Laird GM,Wheeler RT,Alexander BD,Perfect JR,Gao JL,Kullberg BJ,Netea MG,Murphy PM
12-9021 was used in Flow cytometry/Cell sorting to elucidate the roles of innate immune cells in the pathogenesis of C. albicans.
Sun Dec 01 00:00:00 EST 2013
Protective role of Toll-like receptor 4 in experimental gonococcal infection of female mice.
Mucosal immunology
Packiam M,Wu H,Veit SJ,Mavrogiorgos N,Jerse AE,Ingalls RR
12-9021 was used in Flow cytometry/Cell sorting to provide evidence that TLR4-regulated factors modulate early inflammatory responses to gonococcal infection in the female reproductive tract and control bacterial replication.
Sun Jan 01 00:00:00 EST 2012
Macrophage p38 mitogen-activated protein kinase activity regulates invariant natural killer T-cell responses during Borrelia burgdorferi infection.
The Journal of infectious diseases
Hawley K,Navasa N,Olson CM,Bates TC,Garg R,Hedrick MN,Conze D,Rincón M,Anguita J
12-9021 was used in Flow cytometry/Cell sorting to demonstrate that p38 mitogen-activated protein kinase-mediated responses are critical components to the immune response to Borrelia burgdorferi.
Sun Jul 15 00:00:00 EDT 2012
Comparison of blood monocytes and adipose tissue macrophages in a mouse model diet-induced weight gain.
Comparative medicine
McFarlin BK,Carpenter KC,Strohacker K,Breslin WL
12-9021 was used in Flow cytometry/Cell sorting to compare blood monocytes and adipose tissue macrophages in diet-induced weight gain in mice.
Sat Dec 01 00:00:00 EST 2012
Sex-specific signaling through Toll-Like Receptors 2 and 4 contributes to survival outcome of Coxsackievirus B3 infection in C57Bl/6 mice.
Biology of sex differences
Roberts BJ,Dragon JA,Moussawi M,Huber SA
12-9021 was used in Flow cytometry/Cell sorting to determine which TLRs show differential expression in CVB3 infected mice corresponding to male susceptibility and female resistance in Coxsackievirus B3.
Sat Dec 15 00:00:00 EST 2012
Impact of enzymatic tissue disintegration on the level of surface molecule expression and immune cell function.
European journal of microbiology & immunology
Autengruber A,Gereke M,Hansen G,Hennig C,Bruder D
12-9021 was used in Flow cytometry/Cell sorting to indicate that enzymatic tissue disintegration can have profound effects on the expression of a variety of cell-surface molecules.
Fri Jun 01 00:00:00 EDT 2012
Characterization of iNOS(+) Neutrophil-like ring cell in tumor-bearing mice.
Journal of translational medicine
Virtuoso LP,Harden JL,Sotomayor P,Sigurdson WJ,Yoshimura F,Egilmez NK,Minev B,Kilinc MO
12-9021 was used in Flow cytometry/Cell sorting to investigate whether inducible nitric oxide synthase can serve as a specific marker to identify a homogenous myeloid-derived suppressor cell subset.
Mon Jul 30 00:00:00 EDT 2012
The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
Immunity
Suzuki K,Maruya M,Kawamoto S,Sitnik K,Kitamura H,Agace WW,Fagarasan S
12-9021 was used in Flow cytometry/Cell sorting to investigate whether follicular dendritic cells within the germinal centers directly contribute to the IgA production in Peyer's patches, showing that sensing of environmental stimuli promotes IgA production.
Fri Jul 23 00:00:00 EDT 2010
The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR2.
Immunology
Shamsul HM,Hasebe A,Iyori M,Ohtani M,Kiura K,Zhang D,Totsuka Y,Shibata K
12-9021 was used in Flow cytometry/Cell sorting to investigate how FSL-1 is processed in macrophages after recognition by Toll-like receptor 2.
Tue Jun 01 00:00:00 EDT 2010
Theiler's virus infection induces TLR3-dependent upregulation of TLR2 critical for proinflammatory cytokine production.
Glia
So EY,Kim BS
12-9021 was used in Flow cytometry/Cell sorting to indicate that TMEV utilizes TLR3-induced TLR2 to induce inflammatory cytokines, which are critical to the development of immune-mediated demyelinating disease.
Sat Aug 15 00:00:00 EDT 2009
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.
Immunity
Tsuji M,Suzuki K,Kitamura H,Maruya M,Kinoshita K,Ivanov II,Itoh K,Littman DR,Fagarasan S
12-9021 was used in Flow cytometry/Cell sorting to investigate the sites and mechanisms for T cell-independent IgA synthesis.
Fri Aug 15 00:00:00 EDT 2008
Toll-like receptor 2 down-regulation in established mouse allergic lungs contributes to decreased mycoplasma clearance.
American journal of respiratory and critical care medicine
Wu Q,Martin RJ,Lafasto S,Efaw BJ,Rino JG,Harbeck RJ,Chu HW
12-9021 was used in Flow cytometry/Cell sorting to investigate the effect of established allergic airway inflammation on host immunity and the elimination of Mycoplasma pneumoniae from the lungs.
Tue Apr 01 00:00:00 EDT 2008
Toll-like receptor 2 deficiency delays pneumococcal phagocytosis and impairs oxidative killing by granulocytes.
Infection and immunity
Letiembre M,Echchannaoui H,Bachmann P,Ferracin F,Nieto C,Espinosa M,Landmann R
12-9021 was used in Flow cytometry/Cell sorting to investigate phagocytosis and bactericidal activity of wild-type (WT) and Toll-like receptor 2 (TLR2)-deficient granulocytes against live S. pneumoniae.
Thu Dec 01 00:00:00 EST 2005