Product References
Therapeutic potential of highly functional codon-optimized microutrophin for muscle-specific expression.
Scientific reports
Starikova AV,Skopenkova VV,Polikarpova AV,Reshetov DA,Vassilieva SG,Velyaev OA,Shmidt AA,Savchenko IM,Soldatov VO,Egorova TV,Bardina MV
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunohistochemistry
Mon Jan 17 00:00:00 EST 2022
Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss.
The Journal of clinical investigation
Yu W,Zhong L,Yao L,Wei Y,Gui T,Li Z,Kim H,Holdreith N,Jiang X,Tong W,Dyment N,Liu XS,Yang S,Choi Y,Ahn J,Qin L
13-0081 was used in Flow cytometry/Cell sorting to identify MALPs as a critical player in controlling bone remodeling during normal bone metabolism and pathological bone loss in a RANKL-dependent fashion.
Tue Jan 19 00:00:00 EST 2021
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
The Journal of experimental medicine
Heindl S,Ricci A,Carofiglio O,Zhou Q,Arzberger T,Lenart N,Franzmeier N,Hortobagyi T,Nelson PT,Stowe AM,Denes A,Edbauer D,Liesz A
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells.
Frontiers in immunology
Di Giorgio E,Wang L,Xiong Y,Christensen LM,Akimova T,Han R,Samanta A,Trevisanut M,Brancolini C,Beier UH,Hancock WW
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
Local Sustained GM-CSF Delivery by Genetically Engineered Encapsulated Cells Enhanced Both Cellular and Humoral SARS-CoV-2 Spike-Specific Immune Response in an Experimental Murine Spike DNA Vaccination Model.
Vaccines
Vernet R,Charrier E,Cosset E,Fièvre S,Tomasello U,Grogg J,Mach N
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon May 10 00:00:00 EDT 2021
Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction.
eLife
Ramos MIP,Tian L,de Ruiter EJ,Song C,Paucarmayta A,Singh A,Elshof E,Vijver SV,Shaik J,Bosiacki J,Cusumano Z,Jensen C,Willumsen N,Karsdal MA,Liu L,Langermann S,Willems S,Flies D,Meyaard L
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Jun 14 00:00:00 EDT 2021
The subunits of IL-12, originating from two distinct cells, can functionally synergize to protect against pathogen dissemination in vivo.
Cell reports
Gerber AN,Abdi K,Singh NJ
13-0081-82 was used in Flow cytometry/Cell sorting to suggest that early secretion of IL-12p40 monomers by sentinel cells at the infection site may help prepare distal host tissues for potential pathogen arrival.
Tue Oct 12 00:00:00 EDT 2021
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
Cell
Pasciuto E,Burton OT,Roca CP,Lagou V,Rajan WD,Theys T,Mancuso R,Tito RY,Kouser L,Callaerts-Vegh Z,de la Fuente AG,Prezzemolo T,Mascali LG,Brajic A,Whyte CE,Yshii L,Martinez-Muriana A,Naughton M,Young A,Moudra A,Lemaitre P,Poovathingal S,Raes J,De Strooper B,Fitzgerald DC,Dooley J,Liston A
13-0081 was used in Flow cytometry/Cell sorting to investigate the function of brain-resident CD4 T cells.
Thu Aug 06 00:00:00 EDT 2020
Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection.
Nature immunology
Aegerter H,Kulikauskaite J,Crotta S,Patel H,Kelly G,Hessel EM,Mack M,Beinke S,Wack A
13-0081 was used in Flow cytometry/Cell sorting to help to understand how transient respiratory infections, a common occurrence in human life, can constantly alter lung immunity by contributing monocyte-derived, recruited cells to the AM population.
Sat Feb 01 00:00:00 EST 2020
Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation.
The Journal of experimental medicine
Devos M,Tanghe G,Gilbert B,Dierick E,Verheirstraeten M,Nemegeer J,de Reuver R,Lefebvre S,De Munck J,Rehwinkel J,Vandenabeele P,Declercq W,Maelfait J
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Jul 06 00:00:00 EDT 2020
Long-term ex vivo expansion of mouse hematopoietic stem cells.
Nature protocols
Wilkinson AC,Ishida R,Nakauchi H,Yamazaki S
13-0081 was used in Flow cytometry/Cell sorting to describe a simple platform for the expansion of functional mouse hematopoietic stem cells ex vivo for >1 month under fully defined albumin-free conditions.
Sat Feb 01 00:00:00 EST 2020
Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.
EMBO molecular medicine
Menga A,Serra M,Todisco S,Riera-Domingo C,Ammarah U,Ehling M,Palmieri EM,Di Noia MA,Gissi R,Favia M,Pierri CL,Porporato PE,Castegna A,Mazzone M
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Oct 07 00:00:00 EDT 2020
Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development.
The Journal of cell biology
Romero-Wolf M,Shin B,Zhou W,Koizumi M,Rothenberg EV,Hosokawa H
13-0081 was used in Flow cytometry/Cell sorting to define a distinct mechanism of Notch signal response that distinguishes the initial stages of murine T cell development.
Mon Oct 05 00:00:00 EDT 2020
High-fat diet induced central adiposity (visceral fat) is associated with increased fibrosis and decreased immune cellularity of the mesenteric lymph node in mice.
European journal of nutrition
Magnuson AM,Regan DP,Booth AD,Fouts JK,Solt CM,Hill JL,Dow SW,Foster MT
13-0081-82 was used in Flow Cytometry to investigate if lymph nodes are inherently distinct and differentially respond to diet-induced obesity much like the adipose depots they reside in.
Mon Jun 01 00:00:00 EDT 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
TIAM2S Mediates Serotonin Homeostasis and Provokes a Pro-Inflammatory Immune Microenvironment Permissive for Colorectal Tumorigenesis.
Cancers
Chan YL,Lai WC,Chen JS,Tseng JT,Chuang PC,Jou J,Lee CT,Sun HS
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunohistochemistry
Wed Jul 08 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
13-0081 was used in Flow cytometry/Cell sorting to show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme decreases the self-renewal capacity of murine chronic myelogenous leukaemia stem cells.
Thu Sep 17 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
13-0081 was used in Flow cytometry/Cell sorting to show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme decreases the self-renewal capacity of murine chronic myelogenous leukaemia stem cells.
Thu Sep 17 00:00:00 EDT 2020
RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes.
Frontiers in immunology
Rana A,de Almeida FC,Paico Montero HA,Gonzales Carazas MM,Bortoluci KR,Sad S,Amarante-Mendes GP
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
A Cu9S5 nanoparticle-based CpG delivery system for synergistic photothermal-, photodynamic- and immunotherapy.
Communications biology
Zhou L,Chen L,Hu X,Lu Y,Liu W,Sun Y,Yao T,Dong C,Shi S
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunohistochemistry
Fri Jul 03 00:00:00 EDT 2020
Loss of testosterone impairs anti-tumor neutrophil function.
Nature communications
Markman JL,Porritt RA,Wakita D,Lane ME,Martinon D,Noval Rivas M,Luu M,Posadas EM,Crother TR,Arditi M
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Mar 31 00:00:00 EDT 2020
IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses.
Nature communications
Evnouchidou I,Chappert P,Benadda S,Zucchetti A,Weimershaus M,Bens M,Caillens V,Koumantou D,Lotersztajn S,van Endert P,Davoust J,Guermonprez P,Hivroz C,Gross DA,Saveanu L
13-0081 was used in Flow cytometry/Cell sorting to reveal a previously unappreciated function of IRAP-dependent endosomal T cell receptor signalling in T cell activation.
Tue Jun 02 00:00:00 EDT 2020
Nuclear imaging-guided PD-L1 blockade therapy increases effectiveness of cancer immunotherapy.
Journal for immunotherapy of cancer
Gao H,Wu Y,Shi J,Zhang X,Liu T,Hu B,Jia B,Wan Y,Liu Z,Wang F
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation.
Science advances
Ma C,Yang D,Wang B,Wu C,Wu Y,Li S,Liu X,Lassen K,Dai L,Yang S
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Methylation of a CGATA element inhibits binding and regulation by GATA-1.
Nature communications
Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M
13-0081 was used in Flow cytometry/Cell sorting to show that the erythroid transcription factor GATA-1 - that typically binds T/AGATA sites - can also recognise CGATA elements, but only if the CpG dinucleotide is unmethylated.
Fri May 22 00:00:00 EDT 2020
Use of Busulfan to Condition Mice for Bone Marrow Transplantation.
STAR protocols
Montecino-Rodriguez E,Dorshkind K
13-0081 was used in Flow cytometry/Cell sorting to describe a protocol for the use of busulfan to condition mice for bone marrow transplantation and several of the variables to consider for effective implementation.
Fri Dec 18 00:00:00 EST 2020
ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
PloS one
Hanson A,Elpek K,Duong E,Shallberg L,Fan M,Johnson C,Wallace M,Mabry GR,Sazinsky S,Pepper L,Shu CJ,Sathyanarayanan S,Zuerndorfer S,Simpson T,Gostissa M,Briskin M,Law D,Michaelson J,Harvey CJ
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Nov 16 00:00:00 EST 2020
Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment.
eLife
Zhong L,Yao L,Tower RJ,Wei Y,Miao Z,Park J,Shrestha R,Wang L,Yu W,Holdreith N,Huang X,Zhang Y,Tong W,Gong Y,Ahn J,Susztak K,Dyment N,Li M,Long F,Chen C,Seale P,Qin L
13-0081 was used in Flow cytometry/Cell sorting to computationally define mesenchymal progenitors at different stages and delineate their bi-lineage differentiation paths in young, adult and aging mice.
Tue Apr 14 00:00:00 EDT 2020
β2-Adrenergic receptor activation on donor cells ameliorates acute GvHD.
JCI insight
Mohammadpour H,Sarow JL,MacDonald CR,Chen GL,Qiu J,Sharma UC,Cao X,Herr MM,Hahn TE,Blazar BR,Repasky EA,McCarthy PL
13-0081-82 was used in Sample Preparation to reveal how β-AR signaling can be targeted to ameliorate GvHD severity while preserving GvT effect.
Thu Jun 18 00:00:00 EDT 2020
Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant.
NPJ vaccines
Van Den Eeckhout B,Van Hoecke L,Burg E,Van Lint S,Peelman F,Kley N,Uzé G,Saelens X,Tavernier J,Gerlo S
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Sep 19 00:00:00 EDT 2023
CD71+ Erythroid Cells in Human Neonates Exhibit Immunosuppressive Properties and Compromise Immune Response Against Systemic Infection in Neonatal Mice.
Frontiers in immunology
Elahi S,Vega-López MA,Herman-Miguel V,Ramírez-Estudillo C,Mancilla-Ramírez J,Motyka B,West L,Oyegbami O
13-0081-82 was used in Flow Cytometry to study the frequency and functionality of CD71+ erythroid cells in the peripheral blood of human newborns/children from 1-day to 5-year and compared them with their counterparts in the neonatal mice.
Mon Dec 28 00:00:00 EST 2020
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.
Nature
Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2019
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.
Nature
Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2019
Paralytic, the Drosophila voltage-gated sodium channel, regulates proliferation of neural progenitors.
Genes & development
Piggott BJ,Peters CJ,He Y,Huang X,Younger S,Jan LY,Jan YN
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunohistochemistry
Sun Dec 01 00:00:00 EST 2019
Paralytic, the Drosophila voltage-gated sodium channel, regulates proliferation of neural progenitors.
Genes & development
Piggott BJ,Peters CJ,He Y,Huang X,Younger S,Jan LY,Jan YN
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunohistochemistry
Sun Dec 01 00:00:00 EST 2019
MicroRNA-21 is Required for Hematopoietic Cell Viability After Radiation Exposure.
International journal of radiation oncology, biology, physics
Puccetti MV,Adams CM,Dan TD,Palagani A,Simone BA,DeAngelis T,Eischen CM,Simone NL
13-0081 was used in Flow cytometry/Cell sorting to identify miR-21 as a critical component of HSPC viability and essential for bone marrow recovery following irradiation. Further investigation is warranted to determine whether miR-21 can be used to stratify patients at risk for hematopoietic toxicity following irradiation.
Thu Aug 01 00:00:00 EDT 2019
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.
Pain research & management
Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Dec 16 00:00:00 EST 2019
Hemozoin produced by mammals confers heme tolerance.
eLife
Pek RH,Yuan X,Rietzschel N,Zhang J,Jackson L,Nishibori E,Ribeiro A,Simmons W,Jagadeesh J,Sugimoto H,Alam MZ,Garrett L,Haldar M,Ralle M,Phillips JD,Bodine DM,Hamza I
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Western Blot
Tue Oct 01 00:00:00 EDT 2019
Dissociating STAT4 and STAT5 Signaling Inhibitory Functions of SOCS3: Effects on CD8 T Cell Responses.
ImmunoHorizons
Hwang JY,Holland JE,Valenteros KB,Sun Y,Usherwood YK,Verissimo AF,McLellan JS,Grigoryan G,Usherwood EJ
13-0081 was used in Flow cytometry/Cell sorting to study the role of SOCS proteins in cytokine signalling via the use of mutants SOCS3.
Wed Nov 20 00:00:00 EST 2019
Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche.
Cell reports
Balzano M,De Grandis M,Vu Manh TP,Chasson L,Bardin F,Farina A,Sergé A,Bidaut G,Charbord P,Hérault L,Bailly AL,Cartier-Michaud A,Boned A,Dalod M,Duprez E,Genever P,Coles M,Bajenoff M,Xerri L,Aurrand-Lions M,Schiff C,Mancini SJC
13-0081 was used in Flow cytometry/Cell sorting to study pro-B cells in their support of stroll cells and their interaction network allowing their retention.
Tue Mar 19 00:00:00 EDT 2019
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.
Immunity
Hu G,Cui K,Fang D,Hirose S,Wang X,Wangsa D,Jin W,Ried T,Liu P,Zhu J,Rothenberg EV,Zhao K
13-0081 was used in Flow cytometry/Cell sorting to find that abrupt genome-wide changes at all three levels of chromatin organization occur during the transition from double-negative stage 2 (DN2) to DN3, accompanying the T lineage commitment.
Tue Feb 20 00:00:00 EST 2018
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment.
Cell stem cell
Yamamoto R,Wilkinson AC,Ooehara J,Lan X,Lai CY,Nakauchi Y,Pritchard JK,Nakauchi H
13-0081 was used in Flow cytometry/Cell sorting to determine the age-related functional changes to the haematopoietic stem cell compartment.
Thu Apr 05 00:00:00 EDT 2018
IL1RAP potentiates multiple oncogenic signaling pathways in AML.
The Journal of experimental medicine
Mitchell K,Barreyro L,Todorova TI,Taylor SJ,Antony-Debré I,Narayanagari SR,Carvajal LA,Leite J,Piperdi Z,Pendurti G,Mantzaris I,Paietta E,Verma A,Gritsman K,Steidl U
13-0081 was used in Flow cytometry/Cell sorting to show that targeting of interleukin-1 receptor accessory protein via RNA interference, genetic deletion, or antibodies inhibits acute myeloid leukaemia pathogenesis in vitro and in vivo.
Mon Jun 04 00:00:00 EDT 2018
STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.
Molecular oncology
Crnčec I,Modak M,Gordziel C,Svinka J,Scharf I,Moritsch S,Pathria P,Schlederer M,Kenner L,Timelthaler G,Müller M,Strobl B,Casanova E,Bayer E,Mohr T,Stöckl J,Friedrich K,Eferl R
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
Inhibiting TrxR suppresses liver cancer by inducing apoptosis and eliciting potent antitumor immunity.
Oncology reports
Lei H,Wang G,Zhang J,Han Q
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2018
Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.
Experimental hematology
Serrano-Lopez J,Nattamai K,Pease NA,Shephard MS,Wellendorf AM,Sertorio M,Smith EA,Geiger H,Wells SI,Cancelas JA,Privette Vinnedge LM
13-0081 was used in Flow cytometry/Cell sorting to investigate the role of DEK in normal hematopoiesis and response to DNA damaging agents in vivo.
Thu Mar 01 00:00:00 EST 2018
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Nature communications
Xu Y,Ikeda S,Sumida K,Yamamoto R,Tanaka H,Minato N
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Mar 02 00:00:00 EST 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunofluorescence
Wed Mar 28 00:00:00 EDT 2018
Type 2 Innate Lymphocytes Actuate Immunity Against Tumours and Limit Cancer Metastasis.
Scientific reports
Saranchova I,Han J,Zaman R,Arora H,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer CG,Welch I,Takei F,Jefferies WA
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunohistochemistry
Tue Feb 13 00:00:00 EST 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Nov 20 00:00:00 EST 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.
Frontiers in physiology
Lim D,Kim W,Lee C,Bae H,Kim J
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Sep 30 00:00:00 EDT 2020
Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity.
Cell reports
Ravussin A,Youm YH,Sander J,Ryu S,Nguyen K,Varela L,Shulman GI,Sidorov S,Horvath TL,Schultze JL,Dixit VD
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Jul 31 00:00:00 EDT 2018
Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2.
Nature communications
Liu Z,Ge Y,Wang H,Ma C,Feist M,Ju S,Guo ZS,Bartlett DL
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Nov 08 00:00:00 EST 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.
Cell stem cell
Tadokoro Y,Hoshii T,Yamazaki S,Eto K,Ema H,Kobayashi M,Ueno M,Ohta K,Arai Y,Hara E,Harada K,Oshima M,Oshima H,Arai F,Yoshimura A,Nakauchi H,Hirao A
13-0081-82 was used in Flow Cytometry to demonstrate the involvement of diet-induced stress on hematopoietic stem cell self-renewal.
Thu May 03 00:00:00 EDT 2018
LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells.
Genome biology
Grigoryan A,Guidi N,Senger K,Liehr T,Soller K,Marka G,Vollmer A,Markaki Y,Leonhardt H,Buske C,Lipka DB,Plass C,Zheng Y,Mulaw MA,Geiger H,Florian MC
13-0081 was used in Flow cytometry/Cell sorting to show that not all histone modifications display a polar localization and that a reduction in H4K16ac amount and loss of epipolarity are specific to aged HSCs.
Wed Nov 07 00:00:00 EST 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
13-0081 was used in Flow cytometry/Cell sorting to study paediatric acute myeloid leukaemia biology, and provide murine models that offer the potential for developing paediatric specific therapeutic strategies.
Tue Dec 11 00:00:00 EST 2018
TGF-β1 Negatively Regulates the Number and Function of Hematopoietic Stem Cells.
Stem cell reports
Wang X,Dong F,Zhang S,Yang W,Yu W,Wang Z,Zhang S,Wang J,Ma S,Wu P,Gao Y,Dong J,Tang F,Cheng T,Ema H
13-0081 was used in Flow cytometry/Cell sorting to examine the effect of transforming growth factor Β1 on haematopoietic stem cell function.
Tue Jul 10 00:00:00 EDT 2018
Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy.
Cell
Cabezas-Wallscheid N,Buettner F,Sommerkamp P,Klimmeck D,Ladel L,Thalheimer FB,Pastor-Flores D,Roma LP,Renders S,Zeisberger P,Przybylla A,Schönberger K,Scognamiglio R,Altamura S,Florian CM,Fawaz M,Vonficht D,Tesio M,Collier P,Pavlinic D,Geiger H,Schroeder T,Benes V,Dick TP,Rieger MA,Stegle O,Trumpp A
13-0081 was used in Flow cytometry/Cell sorting to highlight the impact of dietary vitamin A on the regulation of cell-cycle-mediated stem cell plasticity.
Thu May 18 00:00:00 EDT 2017
Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature.
Cancer cell
Seaman S,Zhu Z,Saha S,Zhang XM,Yang MY,Hilton MB,Morris K,Szot C,Morris H,Swing DA,Tessarollo L,Smith SW,Degrado S,Borkin D,Jain N,Scheiermann J,Feng Y,Wang Y,Li J,Welsch D,DeCrescenzo G,Chaudhary A,Zudaire E,Klarmann KD,Keller JR,Dimitrov DS,St Croix B
13-0081 was used in Flow cytometry/Cell sorting to demonstrate that the cell surface protein CD276/B7-H3 is broadly over-expressed by multiple tumour types on both cancer cells and tumour-infiltrating blood vessels, making it a potentially ideal dual-compartment therapeutic target.
Mon Apr 10 00:00:00 EDT 2017
Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling.
The Journal of clinical investigation
Ying W,Wollam J,Ofrecio JM,Bandyopadhyay G,El Ouarrat D,Lee YS,Oh DY,Li P,Osborn O,Olefsky JM
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.
Science translational medicine
Allen E,Jabouille A,Rivera LB,Lodewijckx I,Missiaen R,Steri V,Feyen K,Tawney J,Hanahan D,Michael IP,Bergers G
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Jun 05 00:00:00 EDT 2017
A type 2 cytokine axis for thymus emigration.
The Journal of experimental medicine
White AJ,Baik S,Parnell SM,Holland AM,Brombacher F,Jenkinson WE,Anderson G
13-0081 was used in Flow cytometry/Cell sorting to show the thymic microenvironment expresses the type 2 IL-4R complex and is functionally responsive to its known ligands, IL-4 and IL-13.
Mon Aug 07 00:00:00 EDT 2017
Pre/pro-B cells generate macrophage populations during homeostasis and inflammation.
Proceedings of the National Academy of Sciences of the United States of America
Audzevich T,Bashford-Rogers R,Mabbott NA,Frampton D,Freeman TC,Potocnik A,Kellam P,Gilroy DW
13-0081 was used in Flow cytometry/Cell sorting to study the developmental plasticity of immature B cells and their role as the source of tissue resident macrophages.
Tue May 16 00:00:00 EDT 2017
A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells.
Frontiers in immunology
Yu Q,Wang X,Fan X
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Diet-induced obesity causes visceral, but not subcutaneous, lymph node hyperplasia via increases in specific immune cell populations.
Cell proliferation
Magnuson AM,Regan DP,Fouts JK,Booth AD,Dow SW,Foster MT
13-0081 was used in Flow cytometry/Cell sorting to investigate whether secondary lymphatics within visceral adiposity contribute to disease risk.
Sun Oct 01 00:00:00 EDT 2017
Eosinophils are required to suppress Th2 responses in Peyer's patches during intestinal infection by nematodes.
Mucosal immunology
Strandmark J,Steinfelder S,Berek C,Kühl AA,Rausch S,Hartmann S
13-0081 was used in Flow cytometry/Cell sorting to study whether eosinophils affect the local T-cell and antibody response in the gut-associated lymphoid tissue during enteric infections.
Mon May 01 00:00:00 EDT 2017
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis.
Chinese medical journal
Cui N,Wang H,Su LX,Zhang JH,Long Y,Liu DW
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Sat May 20 00:00:00 EDT 2017
Immunological phenotype of the murine Lrba knockout.
Immunology and cell biology
Gámez-Díaz L,Neumann J,Jäger F,Proietti M,Felber F,Soulas-Sprauel P,Perruzza L,Grassi F,Kögl T,Aichele P,Kilimann M,Grimbacher B,Jung S
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
The inflammatory phase of fracture healing is influenced by oestrogen status in mice.
European journal of medical research
Haffner-Luntzer M,Fischer V,Prystaz K,Liedert A,Ignatius A
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunofluorescence
Thu Jul 06 00:00:00 EDT 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu May 04 00:00:00 EDT 2017
IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.
Frontiers in neurology
Gao W,Li F,Zhou Z,Xu X,Wu Y,Zhou S,Yin D,Sun D,Xiong J,Jiang R,Zhang J
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Calreticulin is an effective immunologic adjuvant to tumor-associated antigens.
Experimental and therapeutic medicine
Wang J,Gao ZP,Qin S,Liu CB,Zou LL
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Transient Treg depletion enhances therapeutic anti-cancer vaccination.
Immunity, inflammation and disease
Fisher SA,Aston WJ,Chee J,Khong A,Cleaver AL,Solin JN,Ma S,Lesterhuis WJ,Dick I,Holt RA,Creaney J,Boon L,Robinson B,Lake RA
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment.
Nature communications
Kim KD,Bae S,Capece T,Nedelkovska H,de Rubio RG,Smrcka AV,Jun CD,Jung W,Park B,Kim TI,Kim M
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon May 15 00:00:00 EDT 2017
Location of tumor affects local and distant immune cell type and number.
Immunity, inflammation and disease
Hensel JA,Khattar V,Ashton R,Lee C,Siegal GP,Ponnazhagan S
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting.
Scientific reports
Atkin-Smith GK,Paone S,Zanker DJ,Duan M,Phan TK,Chen W,Hulett MD,Poon IK
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Jan 06 00:00:00 EST 2017
Adeno-associated virus serotype rh.10 displays strong muscle tropism following intraperitoneal delivery.
Scientific reports
Ai J,Li J,Gessler DJ,Su Q,Wei Q,Li H,Gao G
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunofluorescence
Mon Jan 09 00:00:00 EST 2017
Identification of inhibitors of myeloid-derived suppressor cells activity through phenotypic chemical screening.
Oncoimmunology
Schröder M,Loos S,Naumann SK,Bachran C,Krötschel M,Umansky V,Helming L,Swee LK
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis.
International journal of medical sciences
Wang H,Li J,Han Q,Yang F,Xiao Y,Xiao M,Xu Y,Su L,Cui N,Liu D
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon May 21 00:00:00 EDT 2018
Tristetraprolin inhibits macrophage IL-27-induced activation of antitumour cytotoxic T cell responses.
Nature communications
Wang Q,Ning H,Peng H,Wei L,Hou R,Hoft DF,Liu J
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Oct 11 00:00:00 EDT 2017
IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion.
JCI insight
Le Saout C,Luckey MA,Villarino AV,Smith M,Hasley RB,Myers TG,Imamichi H,Park JH,O'Shea JJ,Lane HC,Catalfamo M
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Nov 16 00:00:00 EST 2017
Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nature communications
Rossey I,Gilman MS,Kabeche SC,Sedeyn K,Wrapp D,Kanekiyo M,Chen M,Mas V,Spitaels J,Melero JA,Graham BS,Schepens B,McLellan JS,Saelens X
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation.
EBioMedicine
Ma J,Teng X,Wang X,Fan X,Wu Y,Tian M,Zhou Z,Li L
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Progressive Changes in CXCR4 Expression That Define Thymocyte Positive Selection Are Dispensable For Both Innate and Conventional αβT-cell Development.
Scientific reports
Lucas B,White AJ,Parnell SM,Henley PM,Jenkinson WE,Anderson G
Tue Jul 11 00:00:00 EDT 2017
Metabolic maintenance of cell asymmetry following division in activated T lymphocytes.
Nature
Verbist KC,Guy CS,Milasta S,Liedmann S,Kamiński MM,Wang R,Green DR
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Apr 21 00:00:00 EDT 2016
Metabolic maintenance of cell asymmetry following division in activated T lymphocytes.
Nature
Verbist KC,Guy CS,Milasta S,Liedmann S,Kamiński MM,Wang R,Green DR
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Apr 21 00:00:00 EDT 2016
Single-cell analysis of mixed-lineage states leading to a binary cell fate choice.
Nature
Olsson A,Venkatasubramanian M,Chaudhri VK,Aronow BJ,Salomonis N,Singh H,Grimes HL
13-0081 was used in Flow cytometry/Cell sorting to propose that mixed-lineage states are obligatory during cell-fate specification, manifest differing frequencies because of their dynamic instability and are dictated by counteracting gene-regulatory networks.
Thu Sep 29 00:00:00 EDT 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
13-0081 was used in Flow cytometry/Cell sorting to study how OTULIN may be critical in restraining life-threatening spontaneous inflammation and maintaining immune homeostasis.
Thu Aug 25 00:00:00 EDT 2016
Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission.
Immunity
Tian Y,Kuo CF,Akbari O,Ou JH
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue May 17 00:00:00 EDT 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.
Nature cell biology
Buono M,Facchini R,Matsuoka S,Thongjuea S,Waithe D,Luis TC,Giustacchini A,Besmer P,Mead AJ,Jacobsen SE,Nerlov C
13-0081 was used in Magnetic cell separation to investigate the cellular environments supporting initial stages of T cell development within the thymic cortex.
Mon Feb 01 00:00:00 EST 2016
CD8+ T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure.
Journal of autoimmunity
Gravano DM,Al-Kuhlani M,Davini D,Sanders PD,Manilay JO,Hoyer KK
13-0081 was used in Flow cytometry/Cell sorting to investigate whether CD8+ T cells play a non-redundant role in driving bone marrow failure.
Thu Dec 01 00:00:00 EST 2016
Neutrophil Extracellular Traps Enhance Early Inflammatory Response in Sendai Virus-Induced Asthma Phenotype.
Frontiers in immunology
Akk A,Springer LE,Pham CT
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Sep 12 00:00:00 EDT 2016
Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.
Stem cells translational medicine
Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Sun May 15 00:00:00 EDT 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Jun 08 00:00:00 EDT 2016
Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice.
BMC complementary and alternative medicine
Zhang S,Liu X,Mei L,Wang H,Fang F
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Aug 31 00:00:00 EDT 2016
Discovery of a Metastatic Immune Escape Mechanism Initiated by the Loss of Expression of the Tumour Biomarker Interleukin-33.
Scientific reports
Saranchova I,Han J,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer C,Welch I,Wyatt AW,Fazli L,Gleave ME,Jefferies WA
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Sep 13 00:00:00 EDT 2016
Discovery of a Metastatic Immune Escape Mechanism Initiated by the Loss of Expression of the Tumour Biomarker Interleukin-33.
Scientific reports
Saranchova I,Han J,Huang H,Fenninger F,Choi KB,Munro L,Pfeifer C,Welch I,Wyatt AW,Fazli L,Gleave ME,Jefferies WA
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Sep 13 00:00:00 EDT 2016
MHC-I and PirB Upregulation in the Central and Peripheral Nervous System following Sciatic Nerve Injury.
PloS one
Bombeiro AL,Thomé R,Oliveira Nunes SL,Monteiro Moreira B,Verinaud L,Oliveira AL
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunofluorescence
Wed Jul 26 00:00:00 EDT 2017
Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination.
Scientific reports
Stifter K,Schuster C,Schlosser M,Boehm BO,Schirmbeck R
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Jul 11 00:00:00 EDT 2016
Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy.
Nature communications
Chen Q,Xu L,Liang C,Wang C,Peng R,Liu Z
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Oct 21 00:00:00 EDT 2016
Restrained Th17 response and myeloid cell infiltration into the central nervous system by human decidua-derived mesenchymal stem cells during experimental autoimmune encephalomyelitis.
Stem cell research & therapy
Bravo B,Gallego MI,Flores AI,Bornstein R,Puente-Bedia A,Hernández J,de la Torre P,García-Zaragoza E,Perez-Tavarez R,Grande J,Ballester A,Ballester S
13-0081 was used in Flow cytometry/Cell sorting to explore the therapeutic potential of DMSCs for treatment of autoimmune disorders.
Thu Mar 17 00:00:00 EDT 2016
Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells.
eLife
Allison KA,Sajti E,Collier JG,Gosselin D,Troutman TD,Stone EL,Hedrick SM,Glass CK
13-0081 was used in Magnetic cell separation to investigate relationship between the strength of antigenic stimulation and the response of mouse CD4+ T cells.
Mon Jul 04 00:00:00 EDT 2016
Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation.
Scientific reports
Hu HT,Umemori H,Hsueh YP
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunoprecipitation
Thu Sep 15 00:00:00 EDT 2016
p38 MAPK Inhibitor Insufficiently Attenuates HSC Senescence Administered Long-Term after 6 Gy Total Body Irradiation in Mice.
International journal of molecular sciences
Lu L,Wang YY,Zhang JL,Li DG,Meng AM
13-0081 was used in Flow cytometry/Cell sorting to investigate the effects of SB203580 on long-term TBI-induced myelosuppression.
Wed Jun 08 00:00:00 EDT 2016
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Circulation research
Ye YX,Calcagno C,Binderup T,Courties G,Keliher EJ,Wojtkiewicz GR,Iwamoto Y,Tang J,Pérez-Medina C,Mani V,Ishino S,Johnbeck CB,Knigge U,Fayad ZA,Libby P,Weissleder R,Tawakol A,Dubey S,Belanger AP,Di Carli MF,Swirski FK,Kjaer A,Mulder WJ,Nahrendorf M
13-0081 was used in Flow cytometry/Cell sorting to perform (18)F-FLT positron emission tomography-computed tomography was performed in mice, rabbits, and humans with atherosclerosis.
Fri Oct 23 00:00:00 EDT 2015
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.
The Journal of clinical investigation
Wang L,Liu Y,Han R,Beier UH,Bhatti TR,Akimova T,Greene MI,Hiebert SW,Hancock WW
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2015
Distinct germinal center selection at local sites shapes memory B cell response to viral escape.
The Journal of experimental medicine
Adachi Y,Onodera T,Yamada Y,Daio R,Tsuiji M,Inoue T,Kobayashi K,Kurosaki T,Ato M,Takahashi Y
13-0081 was used in Magnetic cell separation to investigate the cellular events dictating the cross-reactive memory B cell responses, showing that distinct germinal center selection at local sites shapes response to viral escape.
Mon Sep 21 00:00:00 EDT 2015
Depletion of B cells induces remission of autoimmune hepatitis in mice through reduced antigen presentation and help to T cells.
Hepatology (Baltimore, Md.)
Béland K,Marceau G,Labardy A,Bourbonnais S,Alvarez F
13-0081 was used in Flow cytometry/Cell sorting to study the immunological changes underlying the autoimmune hepatitis remission caused by B-cell depletion in an experimental model of AIH.
Sun Nov 01 00:00:00 EDT 2015
Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice.
Cardiovascular research
Wan W,Liu Q,Lionakis MS,Marino AP,Anderson SA,Swamydas M,Murphy PM
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
CD31 signals confer immune privilege to the vascular endothelium.
Proceedings of the National Academy of Sciences of the United States of America
Cheung K,Ma L,Wang G,Coe D,Ferro R,Falasca M,Buckley CD,Mauro C,Marelli-Berg FM
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2015
CD31 signals confer immune privilege to the vascular endothelium.
Proceedings of the National Academy of Sciences of the United States of America
Cheung K,Ma L,Wang G,Coe D,Ferro R,Falasca M,Buckley CD,Mauro C,Marelli-Berg FM
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2015
Imaging Tolerance Induction in the Classic Medawar Neonatal Mouse Model: Active Roles of Multiple F1-Donor Cell Types.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Bascom RA,Tao KS,Tollenaar SL,West LJ
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunocytochemistry
Tue Sep 01 00:00:00 EDT 2015
Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells.
Frontiers in immunology
Vogel AJ,Brown DM
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Jul 10 00:00:00 EDT 2015
Premature thymic involution is independent of structural plasticity of the thymic stroma.
European journal of immunology
Franckaert D,Schlenner SM,Heirman N,Gill J,Skogberg G,Ekwall O,Put K,Linterman MA,Dooley J,Liston A
13-0081 was used in Flow cytometry/Cell sorting to investigate thymic involution in FVB/N mice, showing that disruption of the epithelial-endothelial relationship and a progressive loss of pro-T cells precedes involution, and loss of pro-T cells is sufficient to drive premature involution, suggesting that pro-T cells are the main driver of involution.
Fri May 01 00:00:00 EDT 2015
T-bet Is Required for the Rapid Clearance of Attenuated Rabies Virus from Central Nervous System Tissue.
Journal of immunology (Baltimore, Md. : 1950)
Lebrun A,Portocarrero C,Kean RB,Barkhouse DA,Faber M,Hooper DC
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunofluorescence
Sun Nov 01 00:00:00 EDT 2015
A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells.
Cancer biology & therapy
Kawahara M,Takaku H
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon Sep 12 00:00:00 EDT 2016
Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses.
Human vaccines & immunotherapeutics
Rose AH,Hoffmann FW,Hara JH,Urschitz J,Moisyadi S,Hoffmann PR,Bertino P
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Mon May 16 00:00:00 EDT 2016
Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine.
Human vaccines & immunotherapeutics
Teng X,Tian M,Li J,Tan S,Yuan X,Yu Q,Jing Y,Zhang Z,Yue T,Zhou L,Fan X
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Mar 11 00:00:00 EST 2016
MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation.
Stem cell reports
Tan Y,AlKhamees B,Jia D,Li L,Couture JF,Figeys D,Jinushi M,Wang L
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunofluorescence
Tue Nov 10 00:00:00 EST 2015
MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation.
Stem cell reports
Tan Y,AlKhamees B,Jia D,Li L,Couture JF,Figeys D,Jinushi M,Wang L
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunofluorescence
Tue Nov 10 00:00:00 EST 2015
Use of tilapia piscidin 3 (TP3) to protect against MRSA infection in mice with skin injuries.
Oncotarget
Huang HN,Chan YL,Hui CF,Wu JL,Wu CJ,Chen JY
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunohistochemistry
Sat May 30 00:00:00 EDT 2015
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
PloS one
Tähtinen S,Kaikkonen S,Merisalo-Soikkeli M,Grönberg-Vähä-Koskela S,Kanerva A,Parviainen S,Vähä-Koskela M,Hemminki A
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Apr 28 00:00:00 EDT 2016
Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation.
eLife
He L,Zhang Y,Ma G,Tan P,Li Z,Zang S,Wu X,Jing J,Fang S,Zhou L,Wang Y,Huang Y,Hogan PG,Han G,Zhou Y
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Dec 08 00:00:00 EST 2015
Disease severity and mortality can be independently regulated in a mouse model of experimental graft versus host disease.
PloS one
Galvani RG,Lemos R,Areal RB,Salvador PA,Zamboni DS,Wanderley JL,Bonomo A
13-0081 was used in Magnetic cell separation to investigate the exact cause of death in graft versus host disease, showing that disease severity and mortality can be independently regulated.
Mon Oct 19 00:00:00 EDT 2015
Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
The Journal of clinical investigation
Kong G,Wunderlich M,Yang D,Ranheim EA,Young KH,Wang J,Chang YI,Du J,Liu Y,Tey SR,Zhang X,Juckett M,Mattison R,Damnernsawad A,Zhang J,Mulloy JC,Zhang J
13-0081 was used in Flow cytometry/Cell sorting to investigate the effect of combined targeting of MEK/ERK and JAK/STAT signalling on the murine myeloproliferative neoplasm.
Sun Jun 01 00:00:00 EDT 2014
Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes.
Journal of immunology (Baltimore, Md. : 1950)
Geem D,Medina-Contreras O,McBride M,Newberry RD,Koni PA,Denning TL
13-0081 was used in Magnetic cell separation to investigate whether GALT and/or mesenteric lymph nodes are required for intestinal Th17 differentiation, showing that specific microbiota-induced intestinal Th17 differentiation requires MHC class II.
Tue Jul 01 00:00:00 EDT 2014
A new animal model of spontaneous autoimmune peripheral polyneuropathy: implications for Guillain-Barré syndrome.
Acta neuropathologica communications
Yang M,Rainone A,Shi XQ,Fournier S,Zhang J
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Jan 08 00:00:00 EST 2014
Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.
The Journal of biological chemistry
Ito K,Yamazaki S,Yamamoto R,Tajima Y,Yanagida A,Kobayashi T,Kato-Itoh M,Kakuta S,Iwakura Y,Nakauchi H,Kamiya A
13-0081 was used in Flow cytometry/Cell sorting to investigate the precise role and expression pattern of brain-expressed X-linked genes in endocrine and tissue stem/progenitor cells in mice.
Fri Oct 24 00:00:00 EDT 2014
Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis.
The Journal of biological chemistry
Bhattacharya A,Parillon X,Zeng S,Han S,Eissa NT
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Sep 19 00:00:00 EDT 2014
Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells.
Cell
Yamamoto R,Morita Y,Ooehara J,Hamanaka S,Onodera M,Rudolph KL,Ema H,Nakauchi H
13-0081 was used in Flow cytometry/Cell sorting to identify multipotent progenitors of myeloid cells and study differentiation pathways giving rise to common myeloid cells.
Thu Aug 29 00:00:00 EDT 2013
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity.
Nature immunology
Reis BS,Rogoz A,Costa-Pinto FA,Taniuchi I,Mucida D
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Dose-dense chemotherapy improves mechanisms of antitumor immune response.
Cancer research
Chang CL,Hsu YT,Wu CC,Lai YZ,Wang C,Yang YC,Wu TC,Hung CF
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice.
Cardiovascular research
Wan W,Lionakis MS,Liu Q,Roffê E,Murphy PM
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche.
Journal of immunology (Baltimore, Md. : 1950)
Zook EC,Zhang S,Gerstein RM,Witte PL,Le PT
13-0081 was used in Flow cytometry/Cell sorting to report that Foxn1 is expressed in wild-type BM and overexpressed in Foxn1Tg.
Sun Dec 01 00:00:00 EST 2013
Tumor necrosis factor receptor 2-dependent homeostasis of regulatory T cells as a player in TNF-induced experimental metastasis.
Carcinogenesis
Chopra M,Riedel SS,Biehl M,Krieger S,von Krosigk V,Bäuerlein CA,Brede C,Jordan Garrote AL,Kraus S,Schäfer V,Ritz M,Mattenheimer K,Degla A,Mottok A,Einsele H,Wajant H,Beilhack A
13-0081 was used in Flow cytometry/Cell sorting to reveal a novel role for TNF and its receptor, TNFR2, in the progression of metastasis in a melanoma mouse model of lung metastasis.
Sat Jun 01 00:00:00 EDT 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
In vivo CD8+ T cell dynamics in the liver of Plasmodium yoelii immunized and infected mice.
PloS one
Cabrera M,Pewe LL,Harty JT,Frevert U
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Mar 18 00:00:00 EDT 2014
In vivo CD8+ T cell dynamics in the liver of Plasmodium yoelii immunized and infected mice.
PloS one
Cabrera M,Pewe LL,Harty JT,Frevert U
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Mar 18 00:00:00 EDT 2014
A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific manner.
PloS one
Schuster C,Brosi H,Stifter K,Boehm BO,Schirmbeck R
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunofluorescence
Tue Apr 08 00:00:00 EDT 2014
A missing PD-L1/PD-1 coinhibition regulates diabetes induction by preproinsulin-specific CD8 T-cells in an epitope-specific manner.
PloS one
Schuster C,Brosi H,Stifter K,Boehm BO,Schirmbeck R
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Immunofluorescence
Tue Apr 08 00:00:00 EDT 2014
TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.
PLoS genetics
Gómez-Herreros F,Romero-Granados R,Zeng Z,Alvarez-Quilón A,Quintero C,Ju L,Umans L,Vermeire L,Huylebroeck D,Caldecott KW,Cortés-Ledesma F
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Jun 13 00:00:00 EDT 2013
Tumor necrosis factor induces tumor promoting and anti-tumoral effects on pancreatic cancer via TNFR1.
PloS one
Chopra M,Lang I,Salzmann S,Pachel C,Kraus S,Bäuerlein CA,Brede C,Garrote AL,Mattenheimer K,Ritz M,Schwinn S,Graf C,Schäfer V,Frantz S,Einsele H,Wajant H,Beilhack A
13-0081 was used in Flow cytometry/Cell sorting to assess the mechanisms underlying the contribution of tumour necrosis factor to carcinogenesis.
Mon May 12 00:00:00 EDT 2014
Lack of endogenous IL-10 enhances production of proinflammatory cytokines and leads to Brucella abortus clearance in mice.
PloS one
Corsetti PP,de Almeida LA,Carvalho NB,Azevedo V,Silva TM,Teixeira HC,Faria AC,Oliveira SC
13-0081 was used in Flow cytometry/Cell sorting to evaluate the contribution of IL-10 in host immune response and pathology during B. abortus infection.
Sun Jun 15 00:00:00 EDT 2014
Thymus-autonomous T cell development in the absence of progenitor import.
The Journal of experimental medicine
Martins VC,Ruggiero E,Schlenner SM,Madan V,Schmidt M,Fink PJ,von Kalle C,Rodewald HR
13-0081 was used in Flow cytometry/Cell sorting to characterise the previously unrecognised capacity of the thymus to sustain T cell development during bone marrow progenitor deprivation.
Mon Jul 30 00:00:00 EDT 2012
Cell type-specific targeting dissociates the therapeutic from the adverse effects of protein kinase inhibition in allergic skin disease.
Proceedings of the National Academy of Sciences of the United States of America
Ritprajak P,Hayakawa M,Sano Y,Otsu K,Park JM
13-0081 was used in Magnetic cell separation to show that the effect of interfering with p38α signalling can be either therapeutic or adverse depending on the targeted cell type.
Tue Jun 05 00:00:00 EDT 2012
Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.
Oncogene
Darlington Y,Nguyen TA,Moon SH,Herron A,Rao P,Zhu C,Lu X,Donehower LA
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Mar 01 00:00:00 EST 2012
Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model.
Vaccine
Goicochea MA,Zapata JC,Bryant J,Davis H,Salvato MS,Lukashevich IS
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2012
Global transcriptional analysis of primitive thymocytes reveals accelerated dynamics of T cell specification in fetal stages.
Immunogenetics
Belyaev NN,Biró J,Athanasakis D,Fernandez-Reyes D,Potocnik AJ
13-0081 was used in Magnetic cell separation to compare the development of T cells in foetal and adult stages, showing that adult and foetal T cell progenitors.
Wed Aug 01 00:00:00 EDT 2012
Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1.
Genesis (New York, N.Y. : 2000)
Berquam-Vrieze KE,Swing DA,Tessarollo L,Dupuy AJ
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2012
Origins and properties of dental, thymic, and bone marrow mesenchymal cells and their stem cells.
PloS one
Komada Y,Yamane T,Kadota D,Isono K,Takakura N,Hayashi S,Yamazaki H
13-0081 was used in Flow cytometry/Cell sorting to investigate whether mesechymal cells arise from neural crest or mesoderm, revealing the origins and properties of dental, thymic, and bone marrow mesenchymal cells.
Tue May 14 00:00:00 EDT 2013
RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in γδ T cells.
Immunity
Powolny-Budnicka I,Riemann M,Tänzer S,Schmid RM,Hehlgans T,Weih F
13-0081 was used in Flow cytometry/Cell sorting to investigate the contribution of NF-κB to IL-17 production by T cells, showing that RelA and RelB in distinct thymocyte populations control lymphotoxin-dependent IL-17 production.
Fri Mar 25 00:00:00 EDT 2011
Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis.
Blood
Libregts SF,Gutiérrez L,de Bruin AM,Wensveen FM,Papadopoulos P,van Ijcken W,Ozgür Z,Philipsen S,Nolte MA
13-0081 was used in Flow cytometry/Cell sorting to reveal a molecular mechanism by which chronic exposure to IFN-γ induces expression of IRF-1 and ultimately induces anaemia.
Thu Sep 01 00:00:00 EDT 2011
Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice.
EMBO molecular medicine
Ermakova O,Piszczek L,Luciani L,Cavalli FM,Ferreira T,Farley D,Rizzo S,Paolicelli RC,Al-Banchaabouchi M,Nerlov C,Moriggl R,Luscombe NM,Gross C
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2011
T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950)
Wang R,Xie H,Huang Z,Ma J,Fang X,Ding Y,Sun Z
Published figure using CD8a monoclonal antibody (Product # 13-0081-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Hepatic stellate cells function as regulatory bystanders.
Journal of immunology (Baltimore, Md. : 1950)
Ichikawa S,Mucida D,Tyznik AJ,Kronenberg M,Cheroutre H
13-0081 was used in Magnetic cell separation to suggest that HSC can function as regulatory bystanders, and therefore, by promoting Tregs and suppressing Th17 differentiation, they might represent key players in the mechanism that drives liver-induced tolerance.
Sun May 15 00:00:00 EDT 2011
Chronic helminth infection promotes immune regulation in vivo through dominance of CD11cloCD103- dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Smith KA,Hochweller K,Hämmerling GJ,Boon L,MacDonald AS,Maizels RM
13-0081 was used in Flow cytometry/Cell sorting to identify that the preferential expansion of a novel population of CD11c(lo) non-plasmacytoid DCs is associated with the pro-regulatory environment of chronic intestinal helminth infection.
Wed Jun 15 00:00:00 EDT 2011
IL-1β and TNFα-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis.
International immunology
Mori T,Miyamoto T,Yoshida H,Asakawa M,Kawasumi M,Kobayashi T,Morioka H,Chiba K,Toyama Y,Yoshimura A
13-0081 was used in Functional assays to elucidate the role of cytokines in chronic inflammation and joint destruction in rheumatoid arthritis.
Tue Nov 01 00:00:00 EDT 2011
Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway.
PloS one
Heinonen KM,Vanegas JR,Lew D,Krosl J,Perreault C
13-0081 was used in Flow cytometry/Cell sorting to establish a functional role for non-canonical Wnt signalling in hematopoiesis through a pathway involving Wnt4, Fz6, Rac1 and Jnk kinases.
Tue Apr 26 00:00:00 EDT 2011
The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis.
Blood
Kimura A,Rieger MA,Simone JM,Chen W,Wickre MC,Zhu BM,Hoppe PS,O'Shea JJ,Schroeder T,Hennighausen L
13-0081 was used in Flow cytometry/Cell sorting to assess the contribution of the downstream mediating transcription factors STAT5A/B to the development of granulocytes.
Thu Nov 19 00:00:00 EST 2009
c-Myb is required for pro-B cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Fahl SP,Crittenden RB,Allman D,Bender TP
13-0081 was used in Flow cytometry/Cell sorting to demonstrate that c-Myb is absolutely required for the survival and differentiation of CD19(+) B-lineage cells.
Sun Nov 01 00:00:00 EDT 2009
Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2.
Investigative ophthalmology & visual science
Mochimaru H,Usui T,Yaguchi T,Nagahama Y,Hasegawa G,Usui Y,Shimmura S,Tsubota K,Amano S,Kawakami Y,Ishida S
Thu May 01 00:00:00 EDT 2008
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling.
Proceedings of the National Academy of Sciences of the United States of America
Tsuji M,Shinkura R,Kuroda K,Yabe D,Honjo T
13-0081-82 was used in Flow Cytometry to o investigate where and how Notch regulates early T cell differentiation by using specific up-regulation of Notch signaling by Mint knockout.
Tue Jan 30 00:00:00 EST 2007
Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes.
Circulation
Yang Z,Day YJ,Toufektsian MC,Xu Y,Ramos SI,Marshall MA,French BA,Linden J
Tue Nov 07 00:00:00 EST 2006
Roles of OX40 in the development of murine experimental allergic conjunctivitis: exacerbation and attenuation by stimulation and blocking of OX40.
Investigative ophthalmology & visual science
Fukushima A,Yamaguchi T,Ishida W,Fukata K,Yagita H,Ueno H
13-0081 was used in Flow cytometry/Cell sorting to investigate the roles of interaction between OX40 and OX40 ligand in the development of experimental allergic conjunctivitis.
Wed Feb 01 00:00:00 EST 2006
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.jpg?time=20240507?time=20240507 "CD8a Antibody (13-0081-82) in ICC/IF")
.jpg?time=20240507?time=20240507 "CD8a Antibody (13-0081-82) in ICC/IF")
