Product References
NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis.
Frontiers in immunology
Guo X,Xu X,Li T,Yu Q,Wang J,Chen Y,Ding S,Zhu L,Zou G,Zhang X
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Tue Jan 18 00:00:00 EST 2022
SNAP23 is essential for platelet and mast cell development and required in connective tissue mast cells for anaphylaxis.
The Journal of biological chemistry
Cardenas RA,Gonzalez R,Sanchez E,Ramos MA,Cardenas EI,Rodarte AI,Alcazar-Felix RJ,Isaza A,Burns AR,Heidelberger R,Adachi R
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
Secreted Phospholipase A2 Group X Acts as an Adjuvant for Type 2 Inflammation, Leading to an Allergen-Specific Immune Response in the Lung.
Journal of immunology (Baltimore, Md. : 1950)
Ogden HL,Lai Y,Nolin JD,An D,Frevert CW,Gelb MH,Altemeier WA,Hallstrand TS
14-5898-82 was used in Flow Cytometry to demonstrate that exogenous and endogenous sPLA2s play an important role in peripheral sensitization, resulting in airway responses to inhaled Ags.
Mon Jun 15 00:00:00 EDT 2020
Mutant Huntingtin affects toll-like receptor 4 intracellular trafficking and cytokine production in mast cells.
Journal of neuroinflammation
Pérez-Rodríguez MJ,Ibarra-Sánchez A,Román-Figueroa A,Pérez-Severiano F,González-Espinosa C
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Fri Mar 27 00:00:00 EDT 2020
Tespa1 plays a role in the modulation of airway hyperreactivity through the IL-4/STAT6 pathway.
Journal of translational medicine
Yang R,Wang G,Li L,He H,Zheng M,Lu L,Wu S
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Mon Nov 23 00:00:00 EST 2020
Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.
STAR protocols
Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Fri Jun 19 00:00:00 EDT 2020
A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils.
Immunity
Janela B,Patel AA,Lau MC,Goh CC,Msallam R,Kong WT,Fehlings M,Hubert S,Lum J,Simoni Y,Malleret B,Zolezzi F,Chen J,Poidinger M,Satpathy AT,Briseno C,Wohn C,Malissen B,Murphy KM,Maini AA,Vanhoutte L,Guilliams M,Vial E,Hennequin L,Newell E,Ng LG,Musette P,Yona S,Hacini-Rachinel F,Ginhoux F
14-5898 was used in Flow cytometry/Cell sorting to show that skin cDC1s are essential regulators of the innate response in cutaneous immunity and have roles beyond classical antigen presentation.
Tue Apr 16 00:00:00 EDT 2019
Type I interferon limits mast cell-mediated anaphylaxis by controlling secretory granule homeostasis.
PLoS biology
Kobayashi T,Shimabukuro-Demoto S,Tsutsui H,Toyama-Sorimachi N
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2019
GATA2 and PU.1 Collaborate To Activate the Expression of the Mouse Ms4a2 Gene, Encoding FcεRIβ, through Distinct Mechanisms.
Molecular and cellular biology
Ohmori S,Ishijima Y,Numata S,Takahashi M,Sekita M,Sato T,Chugun K,Yamamoto M,Ohneda K
14-5898 was used in Flow cytometry/Cell sorting to show the formation of active chromatin structure and the expression of the mouse Ms4a2 relies on ETS factor PU.1 and chromatin looping factor LDB1.
Fri Nov 15 00:00:00 EST 2019
Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis.
Nature communications
Liu CL,Zhang X,Liu J,Wang Y,Sukhova GK,Wojtkiewicz GR,Liu T,Tang R,Achilefu S,Nahrendorf M,Libby P,Guo J,Zhang JY,Shi GP
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Western Blot
Wed Sep 04 00:00:00 EDT 2019
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.
Nature
Garaycoechea JI,Crossan GP,Langevin F,Mulderrig L,Louzada S,Yang F,Guilbaud G,Park N,Roerink S,Nik-Zainal S,Stratton MR,Patel KJ
14-5898 was used in Flow cytometry/Cell sorting to identify how the choice of DNA-repair pathway and a stringent p53 response limit the transmission of aldehyde-induced mutations in stem cells.
Thu Jan 11 00:00:00 EST 2018
Peripheral PDGFRα+gp38+ mesenchymal cells support the differentiation of fetal liver-derived ILC2.
The Journal of experimental medicine
Koga S,Hozumi K,Hirano KI,Yazawa M,Terooatea T,Minoda A,Nagasawa T,Koyasu S,Moro K
14-5898 was used in Flow cytometry/Cell sorting to suggest that early differentiation of ILC2 occurs in the fetal liver via IL-7 and Notch signaling, whereas final differentiation occurs in the periphery with the aid of PDGFRα+gp38+ cells.
Mon Jun 04 00:00:00 EDT 2018
Glucagon-like peptide 1 receptor signaling attenuates respiratory syncytial virus-induced type 2 responses and immunopathology.
The Journal of allergy and clinical immunology
Bloodworth MH,Rusznak M,Pfister CC,Zhang J,Bastarache L,Calvillo SA,Chappell JD,Boyd KL,Toki S,Newcomb DC,Stier MT,Zhou W,Goleniewska K,Moore ML,Hartert TV,Niswender KD,Peebles RS
14-5898 was used in Flow cytometry/Cell sorting to investigate the effect of activating the GLP-1R signalling pathway on mice mimicking severe respiratory infection.
Wed Aug 01 00:00:00 EDT 2018
Lineage-Specific Analysis of Syk Function in Autoantibody-Induced Arthritis.
Frontiers in immunology
Németh T,Futosi K,Szilveszter K,Vilinovszki O,Kiss-Pápai L,Mócsai A
14-5898 was used in Flow cytometry/Cell sorting to define the lineage(s) in which Syk expression is required for autoantibody-induced arthritis.
Tue May 28 00:00:00 EDT 2019
Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-Mediated Mast Cell Activation, Independent of the Transmembrane Adaptor PAG/CSK-Binding Protein.
Frontiers in immunology
Potuckova L,Draberova L,Halova I,Paulenda T,Draber P
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Mon Oct 07 00:00:00 EDT 2019
Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-Mediated Mast Cell Activation, Independent of the Transmembrane Adaptor PAG/CSK-Binding Protein.
Frontiers in immunology
Potuckova L,Draberova L,Halova I,Paulenda T,Draber P
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Mon Oct 07 00:00:00 EDT 2019
Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-Mediated Mast Cell Activation, Independent of the Transmembrane Adaptor PAG/CSK-Binding Protein.
Frontiers in immunology
Potuckova L,Draberova L,Halova I,Paulenda T,Draber P
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Mon Oct 07 00:00:00 EDT 2019
CCL7 Is a Negative Regulator of Cutaneous Inflammation Following Leishmania major Infection.
Frontiers in immunology
Ford J,Hughson A,Lim K,Bardina SV,Lu W,Charo IF,Lim JK,Fowell DJ
14-5898 was used in Flow cytometry/Cell sorting to determine the role of CCL7 in Leishmania major infection.
Mon Oct 21 00:00:00 EDT 2019
Functional characterization of oxazolone-induced colitis and survival improvement by vagus nerve stimulation.
PloS one
Meroni E,Stakenborg N,Gomez-Pinilla PJ,De Hertogh G,Goverse G,Matteoli G,Verheijden S,Boeckxstaens GE
14-5898 was used in Flow cytometry/Cell sorting to characterise the immune response in oxazolone-induced colitis and study the therapeutic effect of vagus nerve stimulation.
Tue Nov 27 00:00:00 EST 2018
Mast cells acquire MHCII from dendritic cells during skin inflammation.
The Journal of experimental medicine
Dudeck J,Medyukhina A,Fröbel J,Svensson CM,Kotrba J,Gerlach M,Gradtke AC,Schröder B,Speier S,Figge MT,Dudeck A
14-5898 was used in Flow cytometry/Cell sorting to identify an innate intercellular communication arming resident mast cells with key dendritic cell(DC) functions that might contribute to the acute defence potential during critical periods of migration-based DC absence.
Mon Dec 04 00:00:00 EST 2017
Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone.
The Journal of allergy and clinical immunology
Ramirez-Carrozzi V,Sambandam A,Zhou M,Yan D,Kang J,Wu X,Suto E,Baca M,Austin C,Xu M,Lee W,Pappu R
14589882 was used in flow cytometry to study the effect of IL-13 and IL-33 pathways in dysregulated type 2 inflammation.
Wed Feb 01 00:00:00 EST 2017
A mechanism for the induction of type 2 immune responses by a protease allergen in the genital tract.
Proceedings of the National Academy of Sciences of the United States of America
Oh JE,Oh DS,Jung HE,Lee HK
14589882 was used in blocking or activating experiment and flow cytometry to propose that type 2 immunity is induced by a unique mechanism in the genital tract
Tue Feb 14 00:00:00 EST 2017
Treatment with anti-FcεRIα antibody exacerbates EAE and T-cell immunity against myelin.
Neurology(R) neuroimmunology & neuroinflammation
Musio S,Costanza M,Poliani PL,Fontana E,Cominelli M,Abolafio G,Steinman L,Pedotti R
14-5898 was used in functional assays to investigate the effects of targeting the high-affinity receptor for immunoglobulin E that plays a central role in allergic responses.
Mon May 01 00:00:00 EDT 2017
Regulation of plasma histamine levels by the mast cell clock and its modulation by stress.
Scientific reports
Nakamura Y,Ishimaru K,Shibata S,Nakao A
14589882 was used in flow cytometry to report how steady-state plasma histamine levels are regulated and affected by environmental factors
Wed Jan 11 00:00:00 EST 2017
Selective depletion of basophils ameliorates immunoglobulin E-mediated anaphylaxis.
Biochemistry and biophysics reports
Nakamura T,Fukaya T,Uto T,Takagi H,Arimura K,Tono T,Sato K
14-5898 was used in Flow cytometry/Cell sorting to suggest that CD200R3A is reliable cell surface marker for basophils in vivo, and targeting this unique molecule with mAb for the elimination of basophils may serve as a novel therapeutic strategy in ameliorating the allergic diseases.
Wed Mar 01 00:00:00 EST 2017
Inhibition of airway inflammation in a cockroach allergen model of asthma by agonists of miRNA-33b.
Scientific reports
Niu R,Xiao X,Liu B,Li Y,Zhong Y,Ma L
14-5898 was used in Flow cytometry/Cell sorting to study the role of miR-33b in asthma and mast cell biology and identifies novel mechanisms that may contribute to mast cell-related pathological conditions in airway inflammation.
Mon Aug 07 00:00:00 EDT 2017
Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.
The Journal of clinical investigation
Marichal T,Gaudenzio N,El Abbas S,Sibilano R,Zurek O,Starkl P,Reber LL,Pirottin D,Kim J,Chambon P,Roers A,Antoine N,Kawakami Y,Kawakami T,Bureau F,Tam SY,Tsai M,Galli SJ
14589882 was used in flow cytometry to show that deletion of the gene encoding RAB guanine nucleotide exchange factor 1 in keratinocytes severely impairs epidermal barrier function in mice
Thu Dec 01 00:00:00 EST 2016
Carbonic anhydrase enzymes regulate mast cell-mediated inflammation.
The Journal of experimental medicine
Henry EK,Sy CB,Inclan-Rico JM,Espinosa V,Ghanny SS,Dwyer DF,Soteropoulos P,Rivera A,Siracusa MC
14589882 was used in flow cytometry to find a role for Car enzymes in regulating mast cell lineage commitment
Mon Aug 22 00:00:00 EDT 2016
Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa.
Proceedings of the National Academy of Sciences of the United States of America
Oh JE,Kim BC,Chang DH,Kwon M,Lee SY,Kang D,Kim JY,Hwang I,Yu JW,Nakae S,Lee HK
14-5898 was used in Flow cytometry/Cell sorting to provide insight into the mechanisms of homeostasis maintained by commensal bacteria, and reveal a deleterious consequence of dysbiosis in antiviral immune defense.
Tue Feb 09 00:00:00 EST 2016
Mast cell-derived neurotrophin 4 mediates allergen-induced airway hyperinnervation in early life.
Mucosal immunology
Patel KR,Aven L,Shao F,Krishnamoorthy N,Duvall MG,Levy BD,Ai X
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2016
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.
Molecular and cellular biology
Bambouskova M,Polakovicova I,Halova I,Goel G,Draberova L,Bugajev V,Doan A,Utekal P,Gardet A,Xavier RJ,Draber P
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.
Molecular and cellular biology
Bambouskova M,Polakovicova I,Halova I,Goel G,Draberova L,Bugajev V,Doan A,Utekal P,Gardet A,Xavier RJ,Draber P
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
Isolation of Mature (Peritoneum-Derived) Mast Cells and Immature (Bone Marrow-Derived) Mast Cell Precursors from Mice.
PloS one
Meurer SK,Neß M,Weiskirchen S,Kim P,Tag CG,Kauffmann M,Huber M,Weiskirchen R
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Mon Jul 24 00:00:00 EDT 2017
Retinoic Acid Differentially Regulates the Migration of Innate Lymphoid Cell Subsets to the Gut.
Immunity
Kim MH,Taparowsky EJ,Kim CH
14589882 was used in flow cytometry to discuss tissue tropisms of innate lymphoid cells
Tue Jul 21 00:00:00 EDT 2015
Differential use of autophagy by primary dendritic cells specialized in cross-presentation.
Autophagy
Mintern JD,Macri C,Chin WJ,Panozza SE,Segura E,Patterson NL,Zeller P,Bourges D,Bedoui S,McMillan PJ,Idris A,Nowell CJ,Brown A,Radford KJ,Johnston AP,Villadangos JA
14-5898 was used in Flow cytometry/Cell sorting to highlight the differential use of autophagy and its machinery by primary cells equipped with specific immune function.
Fri Apr 22 00:00:00 EDT 2016
Deficiency of FcϵR1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice.
Endocrinology
Lee YJ,Liu C,Liao M,Sukhova GK,Shirakawa J,Abdennour M,Iamarene K,Andre S,Inouye K,Clement K,Kulkarni RN,Banks AS,Libby P,Shi GP
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Western Blot
Sun Nov 01 00:00:00 EDT 2015
A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.
Nature medicine
Schönhuber N,Seidler B,Schuck K,Veltkamp C,Schachtler C,Zukowska M,Eser S,Feyerabend TB,Paul MC,Eser P,Klein S,Lowy AM,Banerjee R,Yang F,Lee CL,Moding EJ,Kirsch DG,Scheideler A,Alessi DR,Varela I,Bradley A,Kind A,Schnieke AE,Rodewald HR,Rad R,Schmid RM,Schneider G,Saur D
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Immunofluorescence
Sat Nov 01 00:00:00 EDT 2014
Therapeutic effect of IVIG on inflammatory arthritis in mice is dependent on the Fc portion and independent of sialylation or basophils.
Journal of immunology (Baltimore, Md. : 1950)
Campbell IK,Miescher S,Branch DR,Mott PJ,Lazarus AH,Han D,Maraskovsky E,Zuercher AW,Neschadim A,Leontyev D,McKenzie BS,Käsermann F
14-5898 was used in Neutralization experiments to investigate the mechanism of action of high-dose i.v. Ig in treating autoimmune and inflammatory diseases.
Sun Jun 01 00:00:00 EDT 2014
Murine mast cells secrete and respond to interleukin-33.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Tung HY,Plunkett B,Huang SK,Zhou Y
14-5898 was used in Flow cytometry/Cell sorting to elucidate the cellular source and regulatory mechanisms of IL-33.
Sat Mar 01 00:00:00 EST 2014
A systems biology approach to the analysis of subset-specific responses to lipopolysaccharide in dendritic cells.
PloS one
Hancock DG,Shklovskaya E,Guy TV,Falsafi R,Fjell CD,Ritchie W,Hancock RE,Fazekas de St Groth B
14-5898 was used in Flow cytometry/Cell sorting to propose a model in which signalling through common pathways are 'fine-tuned' by transcriptional control of subset-specific modulators, causing distinct outcomes.
Tue Oct 13 00:00:00 EDT 2015
Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E.
Immunity
Cheng LE,Hartmann K,Roers A,Krummel MF,Locksley RM
14-5898 was used in Flow cytometry/Cell sorting to investigate the mechanism by which perivascular mast cells acquire IgE from the blood.
Thu Jan 24 00:00:00 EST 2013
T cell factor 1 is required for group 2 innate lymphoid cell generation.
Immunity
Yang Q,Monticelli LA,Saenz SA,Chi AW,Sonnenberg GF,Tang J,De Obaldia ME,Bailis W,Bryson JL,Toscano K,Huang J,Haczku A,Pear WS,Artis D,Bhandoola A
14-5898 was used in Flow cytometry/Cell sorting to study group 2 innate lymphoid cell development.
Thu Apr 18 00:00:00 EDT 2013
Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.
Nature immunology
Roediger B,Kyle R,Yip KH,Sumaria N,Guy TV,Kim BS,Mitchell AJ,Tay SS,Jain R,Forbes-Blom E,Chen X,Tong PL,Bolton HA,Artis D,Paul WE,Fazekas de St Groth B,Grimbaldeston MA,Le Gros G,Weninger W
14-5898 was used in Flow cytometry/Cell sorting to report the identification in normal mouse dermis of an abundant, phenotypically unique group 2 innate lymphoid cell subset that depended on interleukin 7 and constitutively produced IL-13.
Sat Jun 01 00:00:00 EDT 2013
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.
Nature immunology
Taketomi Y,Ueno N,Kojima T,Sato H,Murase R,Yamamoto K,Tanaka S,Sakanaka M,Nakamura M,Nishito Y,Kawana M,Kambe N,Ikeda K,Taguchi R,Nakamizo S,Kabashima K,Gelb MH,Arita M,Yokomizo T,Nakamura M,Watanabe K,Hirai H,Nakamura M,Okayama Y,Ra C,Aritake K,Urade Y,Morimoto K,Sugimoto Y,Shimizu T,Narumiya S,Hara S,Murakami M
14-5898 was used in Flow cytometry/Cell sorting to report that PLA2G3, a mammalian homolog of anaphylactic bee venom phospholipase A2, regulates mast cell maturation via a lipid mediator circuit.
Sat Jun 01 00:00:00 EDT 2013
Protease activity enhances production of thymic stromal lymphopoietin and basophil accumulation in flaky tail mice.
The American journal of pathology
Moniaga CS,Jeong SK,Egawa G,Nakajima S,Hara-Chikuma M,Jeon JE,Lee SH,Hibino T,Miyachi Y,Kabashima K
14-5898 was used in Flow cytometry/Cell sorting to study the interplay between cellular protease activity and filaggrin deficiency in epidermal barrier abnormality as a predisposing factor in atopic dermatitis.
Fri Mar 01 00:00:00 EST 2013
IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Kamijo S,Takeda H,Tokura T,Suzuki M,Inui K,Hara M,Matsuda H,Matsuda A,Oboki K,Ohno T,Saito H,Nakae S,Sudo K,Suto H,Ichikawa S,Ogawa H,Okumura K,Takai T
14-5898 was used in Flow cytometry/Cell sorting to examine the role of protease allergens in the induction of Ab production and airway inflammation.
Wed May 01 00:00:00 EDT 2013
Generation of mast cells from mouse fetus: analysis of differentiation and functionality, and transcriptome profiling using next generation sequencer.
PloS one
Fukuishi N,Igawa Y,Kunimi T,Hamano H,Toyota M,Takahashi H,Kenmoku H,Yagi Y,Matsui N,Akagi M
14-5898 was used in Flow cytometry/Cell sorting to compare the fundamental functions of fetal liver-derived mouse mast cells with those of bone marrow-derived mouse mast cells.
Tue Oct 22 00:00:00 EDT 2013
Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade.
Nature communications
Leyva-Castillo JM,Hener P,Michea P,Karasuyama H,Chan S,Soumelis V,Li M
14-5898 was used in Neutralization experiments to investigate the mechanisms by which thymic stromal lymphopoietin leads to Th2 initiation, showing that it occurs through an orchestrated immune cascade.
Tue Oct 07 00:00:00 EDT 2014
Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation.
Nature medicine
Hill DA,Siracusa MC,Abt MC,Kim BS,Kobuley D,Kubo M,Kambayashi T,Larosa DF,Renner ED,Orange JS,Bushman FD,Artis D
14-5898 was used in Functional assays to identify a pathway through which commensal-derived signals influence basophil haematopoiesis, and susceptibility to Th2 cytokine-dependent inflammation and allergic disease.
Sun Mar 25 00:00:00 EDT 2012
The E3 ubiquitin ligase adaptor Ndfip1 regulates Th17 differentiation by limiting the production of proinflammatory cytokines.
Journal of immunology (Baltimore, Md. : 1950)
Ramon HE,Beal AM,Liu Y,Worthen GS,Oliver PM
14-5898 was used in Flow cytometry/Cell sorting to investigate the role of the E3 ubiquitin ligase adaptor Ndfip1 on Th17 differentiation in mice.
Sun Apr 15 00:00:00 EDT 2012
Thymic stromal lymphopoietin-dependent basophils promote Th2 cytokine responses following intestinal helminth infection.
Journal of immunology (Baltimore, Md. : 1950)
Giacomin PR,Siracusa MC,Walsh KP,Grencis RK,Kubo M,Comeau MR,Artis D
14-5898 was used in Flow cytometry/Cell sorting to suggest that the TSLP-basophil pathway may be a therapeutic target to promote or limit Th2 cytokine-dependent immunity and inflammation.
Thu Nov 01 00:00:00 EDT 2012
Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway.
Nature
Anthony RM,Kobayashi T,Wermeling F,Ravetch JV
14-5898 was used in Flow cytometry/Cell sorting to study the human DC-SIGN lectin in the context of intravenous immunoglobulin anti-inflammatory activity using humanised DC-SIGN mice.
Sun Jun 19 00:00:00 EDT 2011
Identification of semaphorin 4B as a negative regulator of basophil-mediated immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Nakagawa Y,Takamatsu H,Okuno T,Kang S,Nojima S,Kimura T,Kataoka TR,Ikawa M,Toyofuku T,Katayama I,Kumanogoh A
14-5898 was used in Flow cytometry/Cell sorting to screen semaphorins for immune involvement, identifying Sema4B as a suppressor of basophil-mediated Th2-skewing.
Tue Mar 01 00:00:00 EST 2011
Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant.
Blood
Freire T,Zhang X,Dériaud E,Ganneau C,Vichier-Guerre S,Azria E,Launay O,Lo-Man R,Bay S,Leclerc C
14-5898 was used in Flow cytometry/Cell sorting to study dendritic cell antigen uptake and presentation by targeting the antigen receptor, macrophage galactose-type lectin (MGL), with tumor-associated Tn antigens.
Thu Nov 04 00:00:00 EDT 2010
Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks.
The Journal of clinical investigation
Wada T,Ishiwata K,Koseki H,Ishikura T,Ugajin T,Ohnuma N,Obata K,Ishikawa R,Yoshikawa S,Mukai K,Kawano Y,Minegishi Y,Yokozeki H,Watanabe N,Karasuyama H
14-5898 was used in Functional assays to investigate the cellular and molecular mechanisms underlying acquired resistance to Haemaphysalis longicornis ticks in mice.
Sun Aug 01 00:00:00 EDT 2010
Lyn kinase controls basophil GATA-3 transcription factor expression and induction of Th2 cell differentiation.
Immunity
Charles N,Watford WT,Ramos HL,Hellman L,Oettgen HC,Gomez G,Ryan JJ,O'Shea JJ,Rivera J
14-5898 was used in Flow cytometry/Cell sorting to demonstrate that basophil-expressed Lyn kinase exerts regulatory control on Th2 cell differentiation and function.
Fri Apr 17 00:00:00 EDT 2009
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.
Nature immunology
Perrigoue JG,Saenz SA,Siracusa MC,Allenspach EJ,Taylor BC,Giacomin PR,Nair MG,Du Y,Zaph C,van Rooijen N,Comeau MR,Pearce EJ,Laufer TM,Artis D
Wed Jul 01 00:00:00 EDT 2009
IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice.
The Journal of clinical investigation
Jin H,Oyoshi MK,Le Y,Bianchi T,Koduru S,Mathias CB,Kumar L,Le Bras S,Young D,Collins M,Grusby MJ,Wenzel J,Bieber T,Boes M,Silberstein LE,Oettgen HC,Geha RS
Published figure using FceR1 alpha monoclonal antibody (Product # 14-5898-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2009
STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection.
Journal of immunology (Baltimore, Md. : 1950)
Moore ML,Newcomb DC,Parekh VV,Van Kaer L,Collins RD,Zhou W,Goleniewska K,Chi MH,Mitchell D,Boyce JA,Durbin JE,Sturkie C,Peebles RS
14-5898 was used in in vivo experiments to show for the first time that a respiratory virus (RSV) induced basophil accumulation in vivo.
Sat Aug 01 00:00:00 EDT 2009
Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia.
The Journal of experimental medicine
Grayson MH,Cheung D,Rohlfing MM,Kitchens R,Spiegel DE,Tucker J,Battaile JT,Alevy Y,Yan L,Agapov E,Kim EY,Holtzman MJ
14-5898 was used in Immunoprecipitation to define a new pathway for mucous cell metaplasia after transient viral infection.
Mon Oct 29 00:00:00 EDT 2007
A model system using tape stripping for characterization of Langerhans cell-precursors in vivo.
The Journal of investigative dermatology
Holzmann S,Tripp CH,Schmuth M,Janke K,Koch F,Saeland S,Stoitzner P,Romani N
14-5898 was used in Immunohistochemistry to demonstrate an experimental system for the further characterisation of Langerhans cells (LC)-precursors and the conditions necessary for LC-immigration into the epidermis.
Sat May 01 00:00:00 EDT 2004
