Product References
Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity.
PloS one
Deshycka R,Sudaryo V,Huang NJ,Xie Y,Smeding LY,Choi MK,Ploegh HL,Lodish HF,Pishesha N
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Fri Dec 24 00:00:00 EST 2021
GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization.
JCI insight
Kashgari G,Venkatesh S,Refuerzo S,Pham B,Bayat A,Klein RH,Ramos R,Ta AP,Plikus MV,Wang PH,Andersen B
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Wed Sep 08 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
SnRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.
Life science alliance
Valkov N,Das A,Tucker NR,Li G,Salvador AM,Chaffin MD,Pereira De Oliveira Junior G,Kur I,Gokulnath P,Ziegler O,Yeri A,Lu S,Khamesra A,Xiao C,Rodosthenous R,Srinivasan S,Toxavidis V,Tigges J,Laurent LC,Momma S,Kitchen R,Ellinor P,Ghiran I,Das S
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
SnRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.
Life science alliance
Valkov N,Das A,Tucker NR,Li G,Salvador AM,Chaffin MD,Pereira De Oliveira Junior G,Kur I,Gokulnath P,Ziegler O,Yeri A,Lu S,Khamesra A,Xiao C,Rodosthenous R,Srinivasan S,Toxavidis V,Tigges J,Laurent LC,Momma S,Kitchen R,Ellinor P,Ghiran I,Das S
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Cell reports. Medicine
Kosti P,Opzoomer JW,Larios-Martinez KI,Henley-Smith R,Scudamore CL,Okesola M,Taher MYM,Davies DM,Muliaditan T,Larcombe-Young D,Woodman N,Gillett CE,Thavaraj S,Maher J,Arnold JN
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Tue Apr 20 00:00:00 EDT 2021
Sex Matters: Physiological Abundance of Immuno-Regulatory CD71+ Erythroid Cells Impair Immunity in Females.
Frontiers in immunology
Mashhouri S,Koleva P,Huynh M,Okoye I,Shahbaz S,Elahi S
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Mon Dec 20 00:00:00 EST 2021
Inhibition of TGFβ improves hematopoietic stem cell niche and ameliorates cancer-related anemia.
Stem cell research & therapy
Wang B,Wang Y,Chen H,Yao S,Lai X,Qiu Y,Cai J,Huang Y,Wei X,Guan Y,Wang T,Wang J,Xiang AP
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Mon Jan 18 00:00:00 EST 2021
Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Science advances
Heino S,Fang S,Lähde M,Högström J,Nassiri S,Campbell A,Flanagan D,Raven A,Hodder M,Nasreddin N,Xue HH,Delorenzi M,Leedham S,Petrova TV,Sansom O,Alitalo K
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Fri Nov 19 00:00:00 EST 2021
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Cancer cell
Di Genua C,Valletta S,Buono M,Stoilova B,Sweeney C,Rodriguez-Meira A,Grover A,Drissen R,Meng Y,Beveridge R,Aboukhalil Z,Karamitros D,Belderbos ME,Bystrykh L,Thongjuea S,Vyas P,Nerlov C
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Mon May 11 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Methylation of a CGATA element inhibits binding and regulation by GATA-1.
Nature communications
Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Fri May 22 00:00:00 EDT 2020
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Nature communications
Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Fri May 08 00:00:00 EDT 2020
TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration.
Cell stem cell
Yamashita M,Passegué E
16-5921 was used in Flow cytometry/Cell sorting to reveal several TNF-α-mediated pro-survival mechanisms unique to HSCs, highlight an important role for necroptosis in HSC killing, and establish TNF-α as a major pro-survival and pro-regeneration factor for HSCs.
Thu Sep 05 00:00:00 EDT 2019
Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
PLoS genetics
Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
The Journal of clinical investigation
Chennupati V,Veiga DF,Maslowski KM,Andina N,Tardivel A,Yu EC,Stilinovic M,Simillion C,Duchosal MA,Quadroni M,Roberts I,Sankaran VG,MacDonald HR,Fasel N,Angelillo-Scherrer A,Schneider P,Hoang T,Allam R
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Immunohistochemistry
Mon Apr 02 00:00:00 EDT 2018
Transient loss of venous integrity during developmental vascular remodeling leads to red blood cell extravasation and clearance by lymphatic vessels.
Development (Cambridge, England)
Zhang Y,Daubel N,Stritt S,Mäkinen T
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Immunofluorescence
Thu Feb 08 00:00:00 EST 2018
CCDC134 serves a crucial role in embryonic development.
International journal of molecular medicine
Yu B,Zhang T,Xia P,Gong X,Qiu X,Huang J
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Immunohistochemistry
Mon Jan 01 00:00:00 EST 2018
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.
Human molecular genetics
Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
A protocol for generating induced T cells by reprogramming B cells in vivo.
Cell regeneration (London, England)
Weng Q,Hu F,Zhang M,Dong Y,Lv C,Wang Y,Liu X,Wang J
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Mon Aug 07 00:00:00 EDT 2017
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America
Pishesha N,Bilate AM,Wibowo MC,Huang NJ,Li Z,Deshycka R,Bousbaine D,Li H,Patterson HC,Dougan SK,Maruyama T,Lodish HF,Ploegh HL
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Tue Mar 21 00:00:00 EDT 2017
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.
Breast cancer research : BCR
Chamberlin T,D'Amato JV,Arendt LM
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Wed Nov 29 00:00:00 EST 2017
Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown.
JCI insight
Ogura S,Kurata K,Hattori Y,Takase H,Ishiguro-Oonuma T,Hwang Y,Ahn S,Park I,Ikeda W,Kusuhara S,Fukushima Y,Nara H,Sakai H,Fujiwara T,Matsushita J,Ema M,Hirashima M,Minami T,Shibuya M,Takakura N,Kim P,Miyata T,Ogura Y,Uemura A
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Immunohistochemistry
Thu Feb 09 00:00:00 EST 2017
Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program.
Cell reports
Mehta C,Johnson KD,Gao X,Ong IM,Katsumura KR,McIver SC,Ranheim EA,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Tue Sep 19 00:00:00 EDT 2017
Fibroblastic reticular cells of the lymphoid tissues modulate T cell activation threshold during homeostasis via hyperactive cyclooxygenase-2/prostaglandin E2 axis.
Scientific reports
Yu M,Guo G,Zhang X,Li L,Yang W,Bollag R,Cui Y
16-5921 was used in Flow cytometry/Cell sorting to identify an intrinsic mechanism of fibroblastic reticular cells shared between mice and humans for suppressing T cell sensitivity to activation via PGE2.
Tue Jun 13 00:00:00 EDT 2017
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Thu Apr 21 00:00:00 EDT 2016
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.
Nature cell biology
Pietras EM,Mirantes-Barbeito C,Fong S,Loeffler D,Kovtonyuk LV,Zhang S,Lakshminarasimhan R,Chin CP,Techner JM,Will B,Nerlov C,Steidl U,Manz MG,Schroeder T,Passegué E
16-5921 was used in Flow cytometry/Cell sorting to identify a critical regulatory circuit that tailors HSC responses to acute needs, and is likely to underlie deregulated blood homeostasis in chronic inflammation conditions.
Wed Jun 01 00:00:00 EDT 2016
The LMO2 oncogene regulates DNA replication in hematopoietic cells.
Proceedings of the National Academy of Sciences of the United States of America
Sincennes MC,Humbert M,Grondin B,Lisi V,Veiga DF,Haman A,Cazaux C,Mashtalir N,Affar el B,Verreault A,Hoang T
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Tue Feb 02 00:00:00 EST 2016
Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice.
Biochemical and biophysical research communications
Qu X,Li J,Baldwin HS
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Immunofluorescence
Fri Feb 12 00:00:00 EST 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2016
PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal.
Nature
Lee HY,Gao X,Barrasa MI,Li H,Elmes RR,Peters LL,Lodish HF
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Thu Jun 25 00:00:00 EDT 2015
An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development.
The Journal of experimental medicine
Hao B,Naik AK,Watanabe A,Tanaka H,Chen L,Richards HW,Kondo M,Taniuchi I,Kohwi Y,Kohwi-Shigematsu T,Krangel MS
16-5921 was used in Flow cytometry/Cell sorting to provide a novel framework for understanding ASE function for gene expression in double-positive thymocytes.
Mon May 04 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis.
American journal of hematology
Ludwig LS,Cho H,Wakabayashi A,Eng JC,Ulirsch JC,Fleming MD,Lodish HF,Sankaran VG
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Fri May 01 00:00:00 EDT 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality.
Nature communications
Alvarez S,Díaz M,Flach J,Rodriguez-Acebes S,López-Contreras AJ,Martínez D,Cañamero M,Fernández-Capetillo O,Isern J,Passegué E,Méndez J
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Immunohistochemistry
Mon Oct 12 00:00:00 EDT 2015
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.
Cell
Haldar M,Kohyama M,So AY,Kc W,Wu X,Briseño CG,Satpathy AT,Kretzer NM,Arase H,Rajasekaran NS,Wang L,Egawa T,Igarashi K,Baltimore D,Murphy TL,Murphy KM
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.
Nature medicine
Lucas D,Scheiermann C,Chow A,Kunisaki Y,Bruns I,Barrick C,Tessarollo L,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2013
Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros.
Nature immunology
Schjerven H,McLaughlin J,Arenzana TL,Frietze S,Cheng D,Wadsworth SE,Lawson GW,Bensinger SJ,Farnham PJ,Witte ON,Smale ST
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Immunofluorescence
Fri Feb 01 00:00:00 EST 2013
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Thu May 10 00:00:00 EDT 2012
Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling.
Developmental cell
Chhabra A,Lechner AJ,Ueno M,Acharya A,Van Handel B,Wang Y,Iruela-Arispe ML,Tallquist MD,Mikkola HK
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Immunohistochemistry
Tue Mar 13 00:00:00 EDT 2012
The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS.
Blood
Lane SW,Sykes SM,Al-Shahrour F,Shterental S,Paktinat M,Lo Celso C,Jesneck JL,Ebert BL,Williams DA,Gilliland DG
16-5921 was used in Flow cytometry/Cell sorting to reveal that Wnt activation through haploinsufficiency of Apc causes insidious loss of HSC function.
Thu Apr 29 00:00:00 EDT 2010
Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin.
The EMBO journal
Vassen L,Fiolka K,Möröy T
Published figure using TER-119 monoclonal antibody (Product # 16-5921-85) in Flow Cytometry
Wed Jun 07 00:00:00 EDT 2006