Product References
Identification of fibroblast progenitors in the developing mouse thymus.
Development (Cambridge, England)
Ferreirinha P,Pinheiro RGR,Landry JJM,Alves NL
17-5921-82 was used in Flow cytometry/Cell sorting to identify CD140αβ+GP38+SCA-1- as a source of fibroblast progenitors and define SCA-1 as a marker for developmental stages of thymic fibroblast differentiation.
Sun May 15 00:00:00 EDT 2022
Hydrophilic Realgar Nanocrystals Prolong the Survival of Refractory Acute Myeloid Leukemia Mice Through Inducing Multi-Lineage Differentiation and Apoptosis.
International journal of nanomedicine
Wang T,Zhang X,Jia M,Yang A,Liu J,Wen T,Meng J,Xu H
17-5921-82 was used in Flow Cytometry to conclude that ee-As4S4 induced effective and multiple-lineage differentiation and apoptosis of AML cells in the refractory AML mouse model and cell line, suggesting that it holds promising potential as a novel inductive agent in differentiation therapy of AML.
Tue May 24 00:00:00 EDT 2022
Dormant Nfatc1 reporter-marked basal stem/progenitor cells contribute to mammary lobuloalveoli formation.
iScience
Liu R,Hu H,McNeil M,Xu J,Bi X,Lou P,Guerrero-Juarez CF,Dai X,Plikus MV,Shuai J,Yu Z,Lv C
17-5921-82 was used in Flow cytometry/Cell sorting to show that Nfatc1 expression marks a rare population of mammary epithelial cells with the majority being basal epithelial cells.
Fri Mar 18 00:00:00 EDT 2022
Image-seq: spatially resolved single-cell sequencing guided by in situ and in vivo imaging.
Nature methods
Haase C,Gustafsson K,Mei S,Yeh SC,Richter D,Milosevic J,Turcotte R,Kharchenko PV,Sykes DB,Scadden DT,Lin CP
17-5921-82 was used in Flow cytometry/Cell sorting to present Image-seq, a technology that provides single-cell transcriptional data on cells that are isolated from specific spatial locations under image guidance, thus preserving the spatial information of the target cells.
Thu Dec 01 00:00:00 EST 2022
Growth arrest-specific protein 2 (GAS2) interacts with CXCR4 to promote T-cell leukemogenesis partially via c-MYC.
Molecular oncology
Ma W,Wan Y,Zhang J,Yao J,Wang Y,Lu J,Liu H,Huang X,Zhang X,Zhou H,He Y,Wu D,Wang J,Zhao Y
17-5921-82 was used in Flow cytometry/Cell sorting to suggest that targeting the GAS2/CXCR4 axis is a potential therapeutic strategy for T-ALL.
Sat Oct 01 00:00:00 EDT 2022
Single-cell transcriptomics of LepR-positive skeletal cells reveals heterogeneous stress-dependent stem and progenitor pools.
The EMBO journal
Mo C,Guo J,Qin J,Zhang X,Sun Y,Wei H,Cao D,Zhang Y,Zhao C,Xiong Y,Zhang Y,Sun Y,Shen L,Yue R
17-5921-82 was used in Flow cytometry/Cell sorting to map the transcriptomic landscape of adult LepR+ stem and progenitor cells and uncovered cellular and molecular mechanisms underlying their maintenance and lineage specification.
Tue Feb 15 00:00:00 EST 2022
TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity.
Cell stem cell
Muto T,Guillamot M,Yeung J,Fang J,Bennett J,Nadorp B,Lasry A,Redondo LZ,Choi K,Gong Y,Walker CS,Hueneman K,Bolanos LC,Barreyro L,Lee LH,Greis KD,Vasyliev N,Khodadadi-Jamayran A,Nudler E,Lujambio A,Lowe SW,Aifantis I,Starczynowski DT
17-5921-82 was used in Flow cytometry/Cell sorting to identify signaling states that cooperate with pre-leukemic cells and, notably, the study aimed to uncover the role of the ubiquitin ligase TRAF6 in preventing the transition from a pre-leukemic stage to overt myeloid leukemia by regulating MYC through ubiquitination and acetylation mechanisms.
Thu Feb 03 00:00:00 EST 2022
Hormone-Responsive BMP Signaling Expands Myoepithelial Cell Lineages and Prevents Alveolar Precocity in Mammary Gland.
Frontiers in cell and developmental biology
Shao C,Lou P,Liu R,Bi X,Li G,Yang X,Sheng X,Xu J,Lv C,Yu Z
17-5921-82 was used in Flow Cytometry to identify a novel role of BMP signaling in maintaining the identity of myoepithelial cells and suppressing precocious alveolar formation.
Tue Aug 03 00:00:00 EDT 2021
Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity.
PloS one
Deshycka R,Sudaryo V,Huang NJ,Xie Y,Smeding LY,Choi MK,Ploegh HL,Lodish HF,Pishesha N
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Fri Dec 24 00:00:00 EST 2021
GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization.
JCI insight
Kashgari G,Venkatesh S,Refuerzo S,Pham B,Bayat A,Klein RH,Ramos R,Ta AP,Plikus MV,Wang PH,Andersen B
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Wed Sep 08 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
SnRNA sequencing defines signaling by RBC-derived extracellular vesicles in the murine heart.
Life science alliance
Valkov N,Das A,Tucker NR,Li G,Salvador AM,Chaffin MD,Pereira De Oliveira Junior G,Kur I,Gokulnath P,Ziegler O,Yeri A,Lu S,Khamesra A,Xiao C,Rodosthenous R,Srinivasan S,Toxavidis V,Tigges J,Laurent LC,Momma S,Kitchen R,Ellinor P,Ghiran I,Das S
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Cell reports. Medicine
Kosti P,Opzoomer JW,Larios-Martinez KI,Henley-Smith R,Scudamore CL,Okesola M,Taher MYM,Davies DM,Muliaditan T,Larcombe-Young D,Woodman N,Gillett CE,Thavaraj S,Maher J,Arnold JN
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Tue Apr 20 00:00:00 EDT 2021
Heterogeneity of murine periosteum progenitors involved in fracture healing.
eLife
Matthews BG,Novak S,Sbrana FV,Funnell JL,Cao Y,Buckels EJ,Grcevic D,Kalajzic I
17-5921-82 was used in Flow Cytometry to demonstrate that the periosteum is highly enriched with skeletal progenitor cells, and there is heterogeneity in the populations of cells that contribute to mature lineages during periosteal fracture healing.
Tue Feb 09 00:00:00 EST 2021
Sex Matters: Physiological Abundance of Immuno-Regulatory CD71+ Erythroid Cells Impair Immunity in Females.
Frontiers in immunology
Mashhouri S,Koleva P,Huynh M,Okoye I,Shahbaz S,Elahi S
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Mon Dec 20 00:00:00 EST 2021
Inhibition of TGFβ improves hematopoietic stem cell niche and ameliorates cancer-related anemia.
Stem cell research & therapy
Wang B,Wang Y,Chen H,Yao S,Lai X,Qiu Y,Cai J,Huang Y,Wei X,Guan Y,Wang T,Wang J,Xiang AP
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Mon Jan 18 00:00:00 EST 2021
Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Science advances
Heino S,Fang S,Lähde M,Högström J,Nassiri S,Campbell A,Flanagan D,Raven A,Hodder M,Nasreddin N,Xue HH,Delorenzi M,Leedham S,Petrova TV,Sansom O,Alitalo K
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Fri Nov 19 00:00:00 EST 2021
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Cancer cell
Di Genua C,Valletta S,Buono M,Stoilova B,Sweeney C,Rodriguez-Meira A,Grover A,Drissen R,Meng Y,Beveridge R,Aboukhalil Z,Karamitros D,Belderbos ME,Bystrykh L,Thongjuea S,Vyas P,Nerlov C
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Mon May 11 00:00:00 EDT 2020
Emergence of a High-Plasticity Cell State during Lung Cancer Evolution.
Cancer cell
Marjanovic ND,Hofree M,Chan JE,Canner D,Wu K,Trakala M,Hartmann GG,Smith OC,Kim JY,Evans KV,Hudson A,Ashenberg O,Porter CBM,Bejnood A,Subramanian A,Pitter K,Yan Y,Delorey T,Phillips DR,Shah N,Chaudhary O,Tsankov A,Hollmann T,Rekhtman N,Massion PP,Poirier JT,Mazutis L,Li R,Lee JH,Amon A,Rudin CM,Jacks T,Regev A,Tammela T
17-5921-82 was used in Flow Cytometry to profile cellular transcriptomes of lung tumours at different stages.
Mon Aug 10 00:00:00 EDT 2020
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia.
Cell stem cell
Shen C,Sheng Y,Zhu AC,Robinson S,Jiang X,Dong L,Chen H,Su R,Yin Z,Li W,Deng X,Chen Y,Hu YC,Weng H,Huang H,Prince E,Cogle CR,Sun M,Zhang B,Chen CW,Marcucci G,He C,Qian Z,Chen J
17-5921-82 was used in Flow Cytometry to reveal crucial functions of ALKBH5 in leukemogenesis and LSC/LIC self-renewal/maintenance and highlight the therapeutic potential of targeting the ALKBH5/m6A axis.
Thu Jul 02 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
Evaluation of two methods to isolate Schwann cells from murine sciatic nerve.
Journal of neuroscience methods
Tomlinson JE,Golshadi M,Donahue CJ,Dong L,Cheetham J
17-5921 was used in Flow cytometry/Cell sorting to present two techniques to enrich schwann cells (SC) from other cell populations at the site of peripheral nerve injury.
Sat Feb 01 00:00:00 EST 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Resolving Cell Cycle Speed in One Snapshot with a Live-Cell Fluorescent Reporter.
Cell reports
Eastman AE,Chen X,Hu X,Hartman AA,Pearlman Morales AM,Yang C,Lu J,Kueh HY,Guo S
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Tue Jun 23 00:00:00 EDT 2020
Methylation of a CGATA element inhibits binding and regulation by GATA-1.
Nature communications
Yang L,Chen Z,Stout ES,Delerue F,Ittner LM,Wilkins MR,Quinlan KGR,Crossley M
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Fri May 22 00:00:00 EDT 2020
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.
Nature communications
Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Fri May 08 00:00:00 EDT 2020
Stage Specific Expression Pattern of Alpha-Hemoglobin-Stabilizing-Protein (AHSP) Portrayed in Erythroblast Chronology.
Methods and protocols
Walczak J,Camargo Johnson MD,Muthumalaiappan K
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Tue Jun 30 00:00:00 EDT 2020
A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration.
Nature communications
Matsushita Y,Nagata M,Kozloff KM,Welch JD,Mizuhashi K,Tokavanich N,Hallett SA,Link DC,Nagasawa T,Ono W,Ono N
17-5921-82 was used in Flow cytometry/Cell sorting to further understand how bone marrow stromal cells are activated during regeneration and facilitate osteogenesis.
Thu Jan 16 00:00:00 EST 2020
Bisphosphoglycerate Mutase Deficiency Protects against Cerebral Malaria and Severe Malaria-Induced Anemia.
Cell reports
Xu G,van Bruggen R,Gualtieri CO,Moradin N,Fois A,Vallerand D,De Sa Tavares Russo M,Bassenden A,Lu W,Tam M,Lesage S,Girouard H,Avizonis DZ,Deblois G,Prchal JT,Stevenson M,Berghuis A,Muir T,Rabinowitz J,Vidal SM,Fodil N,Gros P
17-5921 was used in Flow cytometry/Cell sorting to highlight the importance of BPGM as a regulator of hemoglobin/oxyhemoglobin in malaria pathogenesis and suggest a new potential malaria therapeutic target.
Tue Sep 22 00:00:00 EDT 2020
Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target.
Cell reports
Wei H,Xu Y,Wang Y,Xu L,Mo C,Li L,Shen B,Sun Y,Cheng P,Yang L,Pang Y,Qin A,Cao Y,Morrison SJ,Yue R
17-5921 was used in Flow cytometry/Cell sorting to show that fibroblast activation protein(Fap) is an osteogenic suppressor.
Tue Oct 13 00:00:00 EDT 2020
Cycling Stem Cells Are Radioresistant and Regenerate the Intestine.
Cell reports
Sheng X,Lin Z,Lv C,Shao C,Bi X,Deng M,Xu J,Guerrero-Juarez CF,Li M,Wu X,Zhao R,Yang X,Li G,Liu X,Wang Q,Nie Q,Cui W,Gao S,Zhang H,Liu Z,Cong Y,Plikus MV,Lengner CJ,Andersen B,Ren F,Yu Z
17-5921 was used in Flow cytometry/Cell sorting to demonstrate that the DNA damage-resistant Msi1+ cells are cycling ISCs that maintain and regenerate the intestinal epithelium.
Tue Jul 28 00:00:00 EDT 2020
Nestin-GFP transgene labels skeletal progenitors in the periosteum.
Bone
Tournaire G,Stegen S,Giacomini G,Stockmans I,Moermans K,Carmeliet G,van Gastel N
17-5921-82 was used in Flow Cytometry to show that in adult mice, Nes-GFP cells are present in the periosteum and localize closely to blood vessels, but periosteal Nes-GFP cells express SSC and progenitor markers differently compared to Nes-GFP cells in the bone marrow.
Wed Apr 01 00:00:00 EDT 2020
The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment.
Frontiers in immunology
Einwächter H,Heiseke A,Schlitzer A,Gasteiger G,Adler H,Voehringer D,Manz MG,Ruzsics Z,Dölken L,Koszinowski UH,Sparwasser T,Reindl W,Jordan S
17-5921-82 was used in Flow Cytometry to investigate the molecular and cellular mechanisms of inflammation-induced dendritic cell generation.
Mon Apr 19 00:00:00 EDT 2021
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.
Nature medicine
Yousef H,Czupalla CJ,Lee D,Chen MB,Burke AN,Zera KA,Zandstra J,Berber E,Lehallier B,Mathur V,Nair RV,Bonanno LN,Yang AC,Peterson T,Hadeiba H,Merkel T,Körbelin J,Schwaninger M,Buckwalter MS,Quake SR,Butcher EC,Wyss-Coray T
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Sat Jun 01 00:00:00 EDT 2019
Oral ferroportin inhibitor ameliorates ineffective erythropoiesis in a model of β-thalassemia.
The Journal of clinical investigation
Manolova V,Nyffenegger N,Flace A,Altermatt P,Varol A,Doucerain C,Sundstrom H,Dürrenberger F
17-5921-82 was used in Flow Cytometry to identified oral ferroportin inhibitors by screening a library of small molecular weight compounds for modulators of ferroportin internalization.
Mon Dec 09 00:00:00 EST 2019
Muscarinic acetylcholine receptor regulates self-renewal of early erythroid progenitors.
Science translational medicine
Trivedi G,Inoue D,Chen C,Bitner L,Chung YR,Taylor J,Gönen M,Wess J,Abdel-Wahab O,Zhang L
17-5921-82 was used in Flow Cytometry to study how the muscarinic acetylcholine receptor, cholinergic receptor, muscarinic 4 (CHRM4), pathway regulates BFU-E self-renewal and that pharmacological inhibition of CHRM4 corrects anemias of myelodysplastic syndrome (MDS), aging, and hemolysis.
Wed Sep 25 00:00:00 EDT 2019
Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.
Haematologica
Di Genua C,Norfo R,Rodriguez-Meira A,Wen WX,Drissen R,Booth CAG,Povinelli B,Repapi E,Gray N,Carrelha J,Kettyle LM,Jamieson L,Neo WH,Thongjuea S,Nerlov C,Mead AJ
17-5921 was used in Flow cytometry/Cell sorting to study the mechanism behind absence of KRAS signalling mutations in pre-malignant hematopoietic stem cell compartments.
Fri Nov 01 00:00:00 EDT 2019
Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
PLoS genetics
Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.
eLife
Nandakumar SK,McFarland SK,Mateyka LM,Lareau CA,Ulirsch JC,Ludwig LS,Agarwal G,Engreitz JM,Przychodzen B,McConkey M,Cowley GS,Doench JG,Maciejewski JP,Ebert BL,Root DE,Sankaran VG
17-5921-82 was used in Flow Cytometry to identify 77 genes at 38 GWAS loci, with most loci harboring 1-2 candidate genes.
Thu May 09 00:00:00 EDT 2019
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity.
BMC cancer
Wang N,Fan Y,Yuan CM,Song J,Yao Y,Liu W,Gajendran B,Zacksenhaus E,Li Y,Liu J,Hao XJ,Ben-David Y
17-5921-82 was used in Flow Cytometry to isolate three compounds, structurally related to limonoids, from the Melia azedarach leaves.
Fri Aug 02 00:00:00 EDT 2019
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment.
Cell stem cell
Yamamoto R,Wilkinson AC,Ooehara J,Lan X,Lai CY,Nakauchi Y,Pritchard JK,Nakauchi H
17-5921 was used in Flow cytometry/Cell sorting to determine the age-related functional changes to the haematopoietic stem cell compartment.
Thu Apr 05 00:00:00 EDT 2018
Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms.
The Journal of clinical investigation
Zhao B,Mei Y,Cao L,Zhang J,Sumagin R,Yang J,Gao J,Schipma MJ,Wang Y,Thorsheim C,Zhao L,Stalker T,Stein B,Wen QJ,Crispino JD,Abrams CS,Ji P
17-5921 was used in Flow cytometry/Cell sorting to identify pleckstrin-2 as an effector of the JAK2/STAT5 pathway and a key factor in the pathogenesis of JAK2V617F-induced myeloproliferative neoplasms.
Tue Jan 02 00:00:00 EST 2018
MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice.
Human molecular genetics
Gallot YS,Straughn AR,Bohnert KR,Xiong G,Hindi SM,Kumar A
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes.
EBioMedicine
Chen Y,Qin X,An Q,Yi J,Feng F,Yin D,An N,Liu Z,Weng L,Chen S,Hu X,Yin W
17-5921 was used in Flow cytometry/Cell sorting to demonstrate that canonical NLRP3 and non-canonical caspase-11 inflammasomes were activated in bone-associated mesenchymal stromal cells to promote the inflammatory response.
Fri Jun 01 00:00:00 EDT 2018
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
17-5921 was used in Flow cytometry/Cell sorting to identify a regulatory subpopulation of innate lymphoid cells that exists in the gut, and harbour a unique gene identity.
Thu Sep 21 00:00:00 EDT 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
The Journal of clinical investigation
Li H,Liu P,Xu S,Li Y,Dekker JD,Li B,Fan Y,Zhang Z,Hong Y,Yang G,Tang T,Ren Y,Tucker HO,Yao Z,Guo X
17-5921 was used in Flow cytometry/Cell sorting to investigate ageing of MSCs, showing that FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
Mon Apr 03 00:00:00 EDT 2017
ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.
The Journal of experimental medicine
Schwartz C,Khan AR,Floudas A,Saunders SP,Hams E,Rodewald HR,McKenzie ANJ,Fallon PG
17-5921 was used in Flow cytometry/Cell sorting to study how group 2 innate lymphoid cells regulate adaptive Th2 cell functions.
Mon Sep 04 00:00:00 EDT 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
17-5921 was used in Flow cytometry/Cell sorting to propose that Samd14-Enh and an ensemble of anemia-responsive enhancers are essential for erythrocyte regeneration in stress erythropoiesis.
Mon Aug 07 00:00:00 EDT 2017
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America
Pishesha N,Bilate AM,Wibowo MC,Huang NJ,Li Z,Deshycka R,Bousbaine D,Li H,Patterson HC,Dougan SK,Maruyama T,Lodish HF,Ploegh HL
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Tue Mar 21 00:00:00 EDT 2017
Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity.
Breast cancer research : BCR
Chamberlin T,D'Amato JV,Arendt LM
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Wed Nov 29 00:00:00 EST 2017
MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium.
PLoS pathogens
Friedrich C,Mamareli P,Thiemann S,Kruse F,Wang Z,Holzmann B,Strowig T,Sparwasser T,Lochner M
Mon May 01 00:00:00 EDT 2017
Mesenchymal stromal cells can be applied to red blood cells storage as a kind of cellular additive.
Bioscience reports
Chen Y,Zhang J,Gu S,Yin D,An Q,An N,Weng L,Yi J,Xu J,Yin W,Hu X
17-5921 was used in Flow cytometry/Cell sorting to study whether mesenchymal stromal cells are helpful to red blood cells in storage duration at high altitudes.
Tue Oct 31 00:00:00 EDT 2017
The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts.
Science advances
Shi X,Tasdogan A,Huang F,Hu Z,Morrison SJ,DeBerardinis RJ
17-5921 was used in Flow cytometry/Cell sorting to show metabolite profiling can uncover targetable epigenetic requirements for the metastasis of human melanoma cells.
Wed Nov 01 00:00:00 EDT 2017
Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin.
Nature communications
Huang NJ,Pishesha N,Mukherjee J,Zhang S,Deshycka R,Sudaryo V,Dong M,Shoemaker CB,Lodish HF
17-5921 was used in Flow cytometry/Cell sorting to engineer mouse and human red blood cells expressing surface single-domain antibodies against botulinum neurotoxin A, conferring long lasting protection.
Mon Sep 04 00:00:00 EDT 2017
Age-dependent modulation of vascular niches for haematopoietic stem cells.
Nature
Kusumbe AP,Ramasamy SK,Itkin T,Mäe MA,Langen UH,Betsholtz C,Lapidot T,Adams RH
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Thu Apr 21 00:00:00 EDT 2016
CD8+ T cells drive autoimmune hematopoietic stem cell dysfunction and bone marrow failure.
Journal of autoimmunity
Gravano DM,Al-Kuhlani M,Davini D,Sanders PD,Manilay JO,Hoyer KK
17-5921 was used in Flow cytometry/Cell sorting to investigate whether CD8+ T cells play a non-redundant role in driving bone marrow failure.
Thu Dec 01 00:00:00 EST 2016
Salmonella Infection Enhances Erythropoietin Production by the Kidney and Liver, Which Correlates with Elevated Bacterial Burdens.
Infection and immunity
Li LX,Benoun JM,Weiskopf K,Garcia KC,McSorley SJ
17-5921 was used in Flow cytometry/Cell sorting to examine the impact of Salmonella infection on erythroid development.
Sat Oct 01 00:00:00 EDT 2016
Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice.
Biochemical and biophysical research communications
Qu X,Li J,Baldwin HS
17-5921 was used in Immunohistochemistry on frozen tissues to assess the postnatal developmental requirement of Ndrg4 for smooth muscle tissues, macrophages of the spleen and neutrons in mice.
Fri Feb 12 00:00:00 EST 2016
A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis.
Nature communications
Jeric I,Maurer G,Cavallo AL,Raguz J,Desideri E,Tarkowski B,Parrini M,Fischer I,Zatloukal K,Baccarini M
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2016
Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.
Cell reports
Barrett NA,Malouf C,Kapeni C,Bacon WA,Giotopoulos G,Jacobsen SEW,Huntly BJ,Ottersbach K
17-5921 was used in Flow cytometry/Cell sorting to elucidate the contribution of MII-AF4 in B cell acute lymphoblastic leukaemia early development in the mouse embryo.
Tue Jul 26 00:00:00 EDT 2016
Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton.
eLife
Yue R,Shen B,Morrison SJ
17-5921 was used in Flow cytometry/Cell sorting to study how Clec11a/Osteolectin maintains the adult skeleton by promoting the differentiation of mesenchymal progenitors into mature osteoblasts.
Tue Dec 13 00:00:00 EST 2016
Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors.
Nature communications
Cheng H,Ang HY,A El Farran C,Li P,Fang HT,Liu TM,Kong SL,Chin ML,Ling WY,Lim EK,Li H,Huber T,Loh KM,Loh YH,Lim B
17-5921 was used in Flow cytometry/Cell sorting to demonstrate how it is possible to reprogram mouse embryonic fibroblasts into engraftable blood progenitors.
Mon Nov 21 00:00:00 EST 2016
PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal.
Nature
Lee HY,Gao X,Barrasa MI,Li H,Elmes RR,Peters LL,Lodish HF
Thu Jun 25 00:00:00 EDT 2015
Oxidative stress inhibits distant metastasis by human melanoma cells.
Nature
Piskounova E,Agathocleous M,Murphy MM,Hu Z,Huddlestun SE,Zhao Z,Leitch AM,Johnson TM,DeBerardinis RJ,Morrison SJ
17-5921 was used in Flow cytometry/Cell sorting to demonstrate that successful metastasis of melanomas relies on reversible metabolic changes during metastasis that increased their capacity to withstand oxidative stress.
Thu Nov 12 00:00:00 EST 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis.
American journal of hematology
Ludwig LS,Cho H,Wakabayashi A,Eng JC,Ulirsch JC,Fleming MD,Lodish HF,Sankaran VG
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Nitric Oxide-cGMP-PKG Pathway Acts on Orai1 to Inhibit the Hypertrophy of Human Embryonic Stem Cell-Derived Cardiomyocytes.
Stem cells (Dayton, Ohio)
Wang Y,Li ZC,Zhang P,Poon E,Kong CW,Boheler KR,Huang Y,Li RA,Yao X
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2015
Ascorbic acid abrogates microparticle generation and vascular injuries associated with high-pressure exposure.
Journal of applied physiology (Bethesda, Md. : 1985)
Yang M,Bhopale VM,Thom SR
17-5921 was used in Immunofluorescence to reveal that microparticle production occurring with exposures to elevated gas pressure is likely an oxidative stress response.
Wed Jul 01 00:00:00 EDT 2015
Infection with Salmonella enterica Serovar Typhimurium Leads to Increased Proportions of F4/80+ Red Pulp Macrophages and Decreased Proportions of B and T Lymphocytes in the Spleen.
PloS one
Rosche KL,Aljasham AT,Kipfer JN,Piatkowski BT,Konjufca V
17-5921 was used in Flow cytometry/Cell sorting to investigate the cause of Salmonella-induced splenomegaly, showing that significantly increased proportions of F4/80+ red pulp macrophages likely play a major role.
Thu Apr 21 00:00:00 EDT 2016
EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.
PloS one
Charmsaz S,Beckett K,Smith FM,Bruedigam C,Moore AS,Al-Ejeh F,Lane SW,Boyd AW
17-5921 was used in Flow cytometry/Cell sorting to explore the role of EphA2 in haematopoiesis and leukaemogenesis.
Tue May 03 00:00:00 EDT 2016
Standard sub-thermoneutral caging temperature influences radiosensitivity of hematopoietic stem and progenitor cells.
PloS one
Povinelli BJ,Kokolus KM,Eng JW,Dougher CW,Curtin L,Capitano ML,Sailsbury-Ruf CT,Repasky EA,Nemeth MJ
17-5921 was used in Flow cytometry/Cell sorting to demonstrate that chronic stress of laboratory mice increases the resistance of hematopoietic stem and progenitor cells to irradiation-induced apoptosis.
Tue Feb 09 00:00:00 EST 2016
CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections.
European journal of immunology
Bakocevic N,Claser C,Yoshikawa S,Jones LA,Chew S,Goh CC,Malleret B,Larbi A,Ginhoux F,de Lafaille MC,Karasuyama H,Renia L,Ng LG
17-5921 was used in Flow cytometry/Cell sorting to study the CD41 expression within basophils from the blood during both steady state and malarial inections within mice.
Sun Jun 01 00:00:00 EDT 2014
Epigenetic silencing of Bim transcription by Spi-1/PU.1 promotes apoptosis resistance in leukaemia.
Cell death and differentiation
Ridinger-Saison M,Evanno E,Gallais I,Rimmelé P,Selimoglu-Buet D,Sapharikas E,Moreau-Gachelin F,Guillouf C
17-5921 was used in Flow cytometry/Cell sorting to demonstrate that transcription factor Spi-1 inhibits mitochondrial apoptosis through transcriptional repression of Bim.
Sun Sep 01 00:00:00 EDT 2013
CD8(+) T cell activation by murine erythroblasts infected with malaria parasites.
Scientific reports
Imai T,Ishida H,Suzue K,Hirai M,Taniguchi T,Okada H,Suzuki T,Shimokawa C,Hisaeda H
17-5921 was used in Flow cytometry/Cell sorting to examine the parasitism of erythroblasts by P. falciparum and P. vivax and the immune response towards them.
Mon Sep 16 00:00:00 EDT 2013
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
Published figure using TER-119 monoclonal antibody (Product # 17-5921-82) in Flow Cytometry
Thu May 10 00:00:00 EDT 2012
IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.
Blood
Balkhi MY,Willette-Brown J,Zhu F,Chen Z,Liu S,Guttridge DC,Karin M,Hu Y
17-5921-82 was used in Flow Cytometry to demonstrate that IKKα regulates B-lineage commitment via combined canonical and noncanonical NF-κB transcriptional activities to target Pax5 expression during hematopoiesis.
Thu Jun 07 00:00:00 EDT 2012
ZBTB1 is a determinant of lymphoid development.
The Journal of experimental medicine
Siggs OM,Li X,Xia Y,Beutler B
17-5921 was used in Flow cytometry/Cell sorting to identify a mutation causative of complete and cell-intrinsic T cell deficiency.
Mon Jan 16 00:00:00 EST 2012
Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance.
The EMBO journal
Kasler HG,Lim HW,Mottet D,Collins AM,Lee IS,Verdin E
17-5921 was used in Flow cytometry/Cell sorting to examine the effect of blocking TCR-dependent nuclear export of HDAC7 during thymic selection, showing that HDAC7 is required for immune self-tolerance.
Wed Nov 28 00:00:00 EST 2012
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.
Genes & development
Sankaran VG,Ludwig LS,Sicinska E,Xu J,Bauer DE,Eng JC,Patterson HC,Metcalf RA,Natkunam Y,Orkin SH,Sicinski P,Lander ES,Lodish HF
17-5921 was used in Flow cytometry/Cell sorting to illustrate how cell type-specific specialisation can occur for general cell cycle components.
Sat Sep 15 00:00:00 EDT 2012
Angiopoietin-1 promotes endothelial differentiation from embryonic stem cells and induced pluripotent stem cells.
Blood
Joo HJ,Kim H,Park SW,Cho HJ,Kim HS,Lim DS,Chung HM,Kim I,Han YM,Koh GY
17-5921 was used in Flow cytometry/Cell sorting to study the role of Ang1/Tie2 signalling in ESC differentiation.
Thu Aug 25 00:00:00 EDT 2011
Stromal vascular fraction from adipose tissue forms profound vascular network through the dynamic reassembly of blood endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology
Koh YJ,Koh BI,Kim H,Joo HJ,Jin HK,Jeon J,Choi C,Lee DH,Chung JH,Cho CH,Park WS,Ryu JK,Suh JK,Koh GY
17-5921 was used in Flow cytometry/Cell sorting to demonstrate that direct implantation of stromal vascular fraction from donor adipose tissue can produce a vascular network through blood endothelial cells at the site of implantation.
Sun May 01 00:00:00 EDT 2011
Efficient tumour formation by single human melanoma cells.
Nature
Quintana E,Shackleton M,Sabel MS,Fullen DR,Johnson TM,Morrison SJ
17-5921 was used in Flow cytometry/Cell sorting to investigate the extent to which NOD/SCID mice underestimate the frequency of tumourigenic human cancer cells, showing efficient tumour formation by single human melanoma cells.
Thu Dec 04 00:00:00 EST 2008
The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis.
Blood
Tober J,Koniski A,McGrath KE,Vemishetti R,Emerson R,de Mesy-Bentley KK,Waugh R,Palis J
17-5921 was used in Flow cytometry/Cell sorting to elucidate and better define the developmental origins of the megakaryocyte cell lineage.
Thu Feb 15 00:00:00 EST 2007
