Product References
Dissociation and flow cytometric isolation of murine intestinal epithelial cells for multi-omic profiling.
STAR protocols
Ge Y,Zadeh M,Mohamadzadeh M
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Mar 17 00:00:00 EDT 2023
Major depression-related factor NEGR1 controls salivary secretion in mouse submandibular glands.
iScience
Lee J,Kim S,Lee B,Kim YB,Kim KH,Chung G,Lee SJ,Lee S,Sun W,Park HK,Choi SY
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri May 19 00:00:00 EDT 2023
Generation of liver mesenchyme and ductal cell organoid co-culture using cell self-aggregation and droplet microfluidics.
STAR protocols
Dowbaj AM,Kohler TN,Cordero-Espinoza L,Hollfelder F,Huch M
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2023
Bipotent transitional liver progenitor cells contribute to liver regeneration.
Nature genetics
Pu W,Zhu H,Zhang M,Pikiolek M,Ercan C,Li J,Huang X,Han X,Zhang Z,Lv Z,Li Y,Liu K,He L,Liu X,Heim MH,Terracciano LM,Tchorz JS,Zhou B
17-5791-82 was used in Flow cytometry/Cell sorting to identify a transitional liver progenitor cell (TLPC), which originates from biliary epithelial cells and differentiates into hepatocytes during regeneration from severe liver injury.
Sat Apr 01 00:00:00 EDT 2023
Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas.
Cell discovery
Zhao H,Huang X,Liu Z,Lai L,Sun R,Shen R,Li Y,He L,Pu W,Lv Z,Li Y,Han X,Liu X,Zhou B
17-5791-82 was used in Flow cytometry/Cell sorting to suggest that the lineage transdifferentiation happens between acinar cells and ductal cells in the pancreatic exocrine glands under specific conditions.
Tue Jan 03 00:00:00 EST 2023
Endosialin-positive tumor-derived pericytes promote tumor progression through impeding the infiltration of CD8+ T cells in clear cell renal cell carcinoma.
Cancer immunology, immunotherapy : CII
Lu T,Zhang J,Lu S,Yang F,Gan L,Wu X,Song H,Liu S,Xu C,Han D,Yang B,Wen W,Qin W,Yang L
17-5791-82 was used in Flow cytometry/Cell sorting to analyzed the relationship between endosialin (EN) expression and cytotoxic T-lymphocyte.
Thu Jun 01 00:00:00 EDT 2023
Developmental diversity and unique sensitivity to injury of lung endothelial subtypes during postnatal growth.
iScience
Zanini F,Che X,Knutsen C,Liu M,Suresh NE,Domingo-Gonzalez R,Dou SH,Zhang D,Pryhuber GS,Jones RC,Quake SR,Cornfield DN,Alvira CM
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Mar 17 00:00:00 EDT 2023
Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis.
JCI insight
Cooley JC,Javkhlan N,Wilson JA,Foster DG,Edelman BL,Ortiz LA,Schwartz DA,Riches DW,Redente EF
17-5791-82 was used in Flow cytometry/Cell sorting to demonstrate that antiapoptotic BCL-2 family members are expressed by fibroblasts in both human and murine progressive fibrotic lung disease, that these fibroblasts are highly primed, and that treatment with ABT-263 induced fibroblast apoptosis and reduced fibrosis in 2 preclinical models of PF-ILD.
Wed Feb 08 00:00:00 EST 2023
Enteric viruses replicate in salivary glands and infect through saliva.
Nature
Ghosh S,Kumar M,Santiana M,Mishra A,Zhang M,Labayo H,Chibly AM,Nakamura H,Tanaka T,Henderson W,Lewis E,Voss O,Su Y,Belkaid Y,Chiorini JA,Hoffman MP,Altan-Bonnet N
17-5791-82 was used in Flow cytometry/Cell sorting to uncover a new transmission route for enteric viruses with implications for therapeutics, diagnostics and importantly sanitation measures to prevent spread through saliva.
Fri Jul 01 00:00:00 EDT 2022
Enteric viruses replicate in salivary glands and infect through saliva.
Nature
Ghosh S,Kumar M,Santiana M,Mishra A,Zhang M,Labayo H,Chibly AM,Nakamura H,Tanaka T,Henderson W,Lewis E,Voss O,Su Y,Belkaid Y,Chiorini JA,Hoffman MP,Altan-Bonnet N
17-5791-82 was used in Flow cytometry/Cell sorting to uncover a new transmission route for enteric viruses with implications for therapeutics, diagnostics and importantly sanitation measures to prevent spread through saliva.
Fri Jul 01 00:00:00 EDT 2022
IL-33 induces thymic involution-associated naive T cell aging and impairs host control of severe infection.
Nature communications
Xu L,Wei C,Chen Y,Wu Y,Shou X,Chen W,Lu D,Sun H,Li W,Yu B,Wang X,Zhang X,Yu Y,Lei Z,Tang R,Zhu J,Li Y,Lu L,Zhou H,Zhou S,Su C,Chen X
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Sat Nov 12 00:00:00 EST 2022
A mesenchymal to epithelial switch in Fgf10 expression specifies an evolutionary-conserved population of ionocytes in salivary glands.
Cell reports
Mauduit O,Aure MH,Delcroix V,Basova L,Srivastava A,Umazume T,Mays JW,Bellusci S,Tucker AS,Hajihosseini MK,Hoffman MP,Makarenkova HP
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Tue Apr 12 00:00:00 EDT 2022
Oncolytic vaccinia virus expressing a bispecific T-cell engager enhances immune responses in EpCAM positive solid tumors.
Frontiers in immunology
Wei M,Zuo S,Chen Z,Qian P,Zhang Y,Kong L,Gao H,Wei J,Dong J
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Dec 02 00:00:00 EST 2022
TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability.
Mucosal immunology
Ninnemann J,Winsauer C,Bondareva M,Kühl AA,Lozza L,Durek P,Lissner D,Siegmund B,Kaufmann SHE,Mashreghi MF,Nedospasov SA,Kruglov AA
17-5791-82 was used in Flow cytometry/Cell sorting to show how anti-TNF therapy induces mucosal healing by increasing IL-22 availability and implicates new therapeutic opportunities for IBD.
Fri Apr 01 00:00:00 EDT 2022
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
17-5791-82 was used in Flow Cytometry to demonstrate that Lin28B promotes lung metastasis of breast cancer by building an immune-suppressive pre-metastatic niche.
Wed Feb 16 00:00:00 EST 2022
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Science advances
Kumar B,Adebayo AK,Prasad M,Capitano ML,Wang R,Bhat-Nakshatri P,Anjanappa M,Simpson E,Chen D,Liu Y,Schilder JM,Colter AB,Maguire C,Temm CJ,Sandusky G,Doud EH,Wijeratne AB,Mosley AL,Broxmeyer HE,Nakshatri H
17-5791-82 was used in Flow Cytometry to demonstrate that tumors collected, processed, and propagated at physiologic O2 compared to ambient air display distinct differences in key signaling networks including LGR5/WNT, YAP, and NRF2/KEAP1, nuclear reactive oxygen species, alternative splicing, and sensitivity to targeted therapies.
Fri Jan 14 00:00:00 EST 2022
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Science advances
Kumar B,Adebayo AK,Prasad M,Capitano ML,Wang R,Bhat-Nakshatri P,Anjanappa M,Simpson E,Chen D,Liu Y,Schilder JM,Colter AB,Maguire C,Temm CJ,Sandusky G,Doud EH,Wijeratne AB,Mosley AL,Broxmeyer HE,Nakshatri H
17-5791-82 was used in Flow Cytometry to demonstrate that tumors collected, processed, and propagated at physiologic O2 compared to ambient air display distinct differences in key signaling networks including LGR5/WNT, YAP, and NRF2/KEAP1, nuclear reactive oxygen species, alternative splicing, and sensitivity to targeted therapies.
Fri Jan 14 00:00:00 EST 2022
Airway basal cells show regionally distinct potential to undergo metaplastic differentiation.
eLife
Zhou Y,Yang Y,Guo L,Qian J,Ge J,Sinner D,Ding H,Califano A,Cardoso WV
17-5791-82 was used in Flow cytometry/Cell sorting to provide novel insights into the origin and impact of basal cell heterogeneity on the establishment of regionally distinct responses of the airway epithelium during injury-repair and in disease conditions.
Fri Sep 30 00:00:00 EDT 2022
BMP4 and Wnt signaling interact to promote mouse tracheal mesenchyme morphogenesis.
American journal of physiology. Lung cellular and molecular physiology
Bottasso-Arias N,Leesman L,Burra K,Snowball J,Shah R,Mohanakrishnan M,Xu Y,Sinner D
17-5791-82 was used in Flow cytometry/Cell sorting to test whether BMP signaling, induced by epithelial Wnt ligands, mediates cartilage formation.
Tue Feb 01 00:00:00 EST 2022
PI3K signaling specifies proximal-distal fate by driving a developmental gene regulatory network in SOX9+ mouse lung progenitors.
eLife
Khattar D,Fernandes S,Snowball J,Guo M,Gillen MC,Jain SS,Sinner D,Zacharias W,Swarr DT
17-5791-82 was used in Flow cytometry/Cell sorting to analyze paired gene expression (RNA-Seq) and chromatin accessibility (ATAC-Seq) data from SOX9+ epithelial progenitor cells (EPCs) during embryonic development in Mus musculus.
Wed Aug 17 00:00:00 EDT 2022
Cells of the human intestinal tract mapped across space and time.
Nature
Elmentaite R,Kumasaka N,Roberts K,Fleming A,Dann E,King HW,Kleshchevnikov V,Dabrowska M,Pritchard S,Bolt L,Vieira SF,Mamanova L,Huang N,Perrone F,Goh Kai'En I,Lisgo SN,Katan M,Leonard S,Oliver TRW,Hook CE,Nayak K,Campos LS,Domínguez Conde C,Stephenson E,Engelbert J,Botting RA,Polanski K,van Dongen S,Patel M,Morgan MD,Marioni JC,Bayraktar OA,Meyer KB,He X,Barker RA,Uhlig HH,Mahbubani KT,Saeb-Parsy K,Zilbauer M,Clatworthy MR,Haniffa M,James KR,Teichmann SA
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Wed Sep 01 00:00:00 EDT 2021
Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.
Immunity
Shmuel-Galia L,Humphries F,Lei X,Ceglia S,Wilson R,Jiang Z,Ketelut-Carneiro N,Foley SE,Pechhold S,Houghton J,Muneeruddin K,Shaffer SA,McCormick BA,Reboldi A,Ward D,Marshak-Rothstein A,Fitzgerald KA
17-5791-82 was used in Flow cytometry/Cell sorting to suggest a positive feedback loop wherein dysbiosis foments the accumulation of STING in intestinal myeloid cells, driving intestinal inflammation.
Tue Jun 08 00:00:00 EDT 2021
Loss of Optineurin Drives Cancer Immune Evasion via Palmitoylation-Dependent IFNGR1 Lysosomal Sorting and Degradation.
Cancer discovery
Du W,Hua F,Li X,Zhang J,Li S,Wang W,Zhou J,Wang W,Liao P,Yan Y,Li G,Wei S,Grove S,Vatan L,Zgodziński W,Majewski M,Wallner G,Chen H,Kryczek I,Fang JY,Zou W
17-5791-82 was used in Flow Cytometry to show that optineurin is a shared node between the IFN and MHC pathways and predicts colorectal cancer patient outcome.
Thu Jul 01 00:00:00 EDT 2021
Mesenchymal Plasticity Regulated by Prrx1 Drives Aggressive Pancreatic Cancer Biology.
Gastroenterology
Feldmann K,Maurer C,Peschke K,Teller S,Schuck K,Steiger K,Engleitner T,Öllinger R,Nomura A,Wirges N,Papargyriou A,Jahan Sarker RS,Ranjan RA,Dantes Z,Weichert W,Rustgi AK,Schmid RM,Rad R,Schneider G,Saur D,Reichert M
17-5791 was used in Flow cytometry/Cell sorting to elucidate the role of cancer-associated fibroblasts plasticity and its impact on pancreatic ductal adenocarcinoma biology.
Fri Jan 01 00:00:00 EST 2021
Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation.
Cell stem cell
Cordero-Espinoza L,Dowbaj AM,Kohler TN,Strauss B,Sarlidou O,Belenguer G,Pacini C,Martins NP,Dobie R,Wilson-Kanamori JR,Butler R,Prior N,Serup P,Jug F,Henderson NC,Hollfelder F,Huch M
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Nov 04 00:00:00 EDT 2021
Gut epithelial IL-27 confers intestinal immunity through the induction of intraepithelial lymphocytes.
The Journal of experimental medicine
Lin CH,Chen MC,Lin LL,Christian DA,Min B,Hunter CA,Lu LF
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12.
Molecular therapy : the journal of the American Society of Gene Therapy
Teng Y,Xu F,Zhang X,Mu J,Sayed M,Hu X,Lei C,Sriwastva M,Kumar A,Sundaram K,Zhang L,Park JW,Chen SY,Zhang S,Yan J,Merchant ML,Zhang X,McClain CJ,Wolfe JK,Adcock RS,Chung D,Palmer KE,Zhang HG
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Wed Aug 04 00:00:00 EDT 2021
Progastrin production transitions from Bmi1+/Prox1+ to Lgr5high cells during early intestinal tumorigenesis.
Translational oncology
Giraud J,Foroutan M,Boubaker-Vitre J,Grillet F,Homayed Z,Jadhav U,Crespy P,Breuker C,Bourgaux JF,Hazerbroucq J,Pignodel C,Brulin B,Shivdasani RA,Jay P,Hollande F,Pannequin J
17-5791 was used in Flow cytometry/Cell sorting to demonstrate that progastrin is produced within intestinal crypts by a subset of Bmi1+/Prox1+/LGR5low endocrine cells, previously shown to act as replacement stem cells in case of mucosal injury.
Mon Feb 01 00:00:00 EST 2021
Progastrin production transitions from Bmi1+/Prox1+ to Lgr5high cells during early intestinal tumorigenesis.
Translational oncology
Giraud J,Foroutan M,Boubaker-Vitre J,Grillet F,Homayed Z,Jadhav U,Crespy P,Breuker C,Bourgaux JF,Hazerbroucq J,Pignodel C,Brulin B,Shivdasani RA,Jay P,Hollande F,Pannequin J
17-5791 was used in Flow cytometry/Cell sorting to demonstrate that progastrin is produced within intestinal crypts by a subset of Bmi1+/Prox1+/LGR5low endocrine cells, previously shown to act as replacement stem cells in case of mucosal injury.
Mon Feb 01 00:00:00 EST 2021
miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine.
Nature communications
Goga A,Yagabasan B,Herrmanns K,Godbersen S,Silva PN,Denzler R,Zünd M,Furter M,Schwank G,Sunagawa S,Hardt WD,Stoffel M
17-5791-82 was used in Flow Cytometry to demonstrate that the microRNA, miR-802, has a pivotal role in the function of the intestinal epithelium.
Mon Jun 07 00:00:00 EDT 2021
miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine.
Nature communications
Goga A,Yagabasan B,Herrmanns K,Godbersen S,Silva PN,Denzler R,Zünd M,Furter M,Schwank G,Sunagawa S,Hardt WD,Stoffel M
17-5791-82 was used in Flow Cytometry to demonstrate that the microRNA, miR-802, has a pivotal role in the function of the intestinal epithelium.
Mon Jun 07 00:00:00 EDT 2021
Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity.
eLife
Shani O,Raz Y,Monteran L,Scharff Y,Levi-Galibov O,Megides O,Shacham H,Cohen N,Silverbush D,Avivi C,Sharan R,Madi A,Scherz-Shouval R,Barshack I,Tsarfaty I,Erez N
17-5791-82 was used in Flow Cytometry to identify Myc as a central regulator of fibroblast rewiring and found that stromal upregulation of Myc transcriptional networks is associated with disease progression in human breast cancer.
Fri Jun 25 00:00:00 EDT 2021
Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity.
eLife
Shani O,Raz Y,Monteran L,Scharff Y,Levi-Galibov O,Megides O,Shacham H,Cohen N,Silverbush D,Avivi C,Sharan R,Madi A,Scherz-Shouval R,Barshack I,Tsarfaty I,Erez N
17-5791-82 was used in Flow Cytometry to identify Myc as a central regulator of fibroblast rewiring and found that stromal upregulation of Myc transcriptional networks is associated with disease progression in human breast cancer.
Fri Jun 25 00:00:00 EDT 2021
Generation and functional characterization of murine mammary organoids.
STAR protocols
Yip HYK,Papa A
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Immunocytochemistry
Fri Sep 17 00:00:00 EDT 2021
Isolation and culture of mouse alveolar type II cells to study type II to type I cell differentiation.
STAR protocols
Chen Q,Liu Y
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Mar 19 00:00:00 EDT 2021
High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity.
Cell reports
Mana MD,Hussey AM,Tzouanas CN,Imada S,Barrera Millan Y,Bahceci D,Saiz DR,Webb AT,Lewis CA,Carmeliet P,Mihaylova MM,Shalek AK,Yilmaz ÖH
17-5791-82 was used in Flow cytometry/Cell sorting to study how inhibition of a high-fat diet (HFD)-activated fatty acid oxidation (FAO) program creates a therapeutic opportunity to counter the effects of a HFD on intestinal stem cells (ISCs) and intestinal tumorigenesis.
Tue Jun 08 00:00:00 EDT 2021
Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition.
Cell reports
Stephens WZ,Kubinak JL,Ghazaryan A,Bauer KM,Bell R,Buhrke K,Chiaro TR,Weis AM,Tang WW,Monts JK,Soto R,Ekiz HA,O'Connell RM,Round JL
17-5791-82 was used in Flow cytometry/Cell sorting to demonstrate a role for IEC-derived MHC class II in constraining microbiota composition and inducing tolerogenic responses against it.
Tue Nov 02 00:00:00 EDT 2021
Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Science advances
Heino S,Fang S,Lähde M,Högström J,Nassiri S,Campbell A,Flanagan D,Raven A,Hodder M,Nasreddin N,Xue HH,Delorenzi M,Leedham S,Petrova TV,Sansom O,Alitalo K
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Nov 19 00:00:00 EST 2021
The HSP-RTK-Akt axis mediates acquired resistance to Ganetespib in HER2-positive breast cancer.
Cell death & disease
Eyermann CE,Haley JD,Alexandrova EM
17-5791 was used in Flow cytometry/Cell sorting to establish Akt as a unifying actionable node downstream of the broadly upregulated HSP/p-RTK resistance program and suggests that Akt co-targeting with Ganetespib may be a superior therapeutic strategy in the clinic.
Tue Jan 26 00:00:00 EST 2021
Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors.
Cell
Wang D,Wang J,Bai L,Pan H,Feng H,Clevers H,Zeng YA
17-5791-82 was used in Flow Cytometry to demonstrate that the adult mouse pancreatic islet contains a population of Procr+ endocrine progenitors.
Thu Mar 19 00:00:00 EDT 2020
Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level.
Cell research
Wang X,Yang L,Wang YC,Xu ZR,Feng Y,Zhang J,Wang Y,Xu CR
17-5791 was used in Flow cytometry/Cell sorting to study cell lineage differentiation during hepatogenesis using single-cell RNA sequencing of whole human and mouse fetal livers throughout development.
Tue Dec 01 00:00:00 EST 2020
Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level.
Cell research
Wang X,Yang L,Wang YC,Xu ZR,Feng Y,Zhang J,Wang Y,Xu CR
17-5791 was used in Flow cytometry/Cell sorting to study cell lineage differentiation during hepatogenesis using single-cell RNA sequencing of whole human and mouse fetal livers throughout development.
Tue Dec 01 00:00:00 EST 2020
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver.
Immunity
Remmerie A,Martens L,Thoné T,Castoldi A,Seurinck R,Pavie B,Roels J,Vanneste B,De Prijck S,Vanhockerhout M,Binte Abdul Latib M,Devisscher L,Hoorens A,Bonnardel J,Vandamme N,Kremer A,Borghgraef P,Van Vlierberghe H,Lippens S,Pearce E,Saeys Y,Scott CL
17-5791 was used in Flow cytometry/Cell sorting to highlight considerable heterogeneity within the macrophage pool and suggest a need for more specific macrophage targeting strategies in metabolic-associated fatty liver disease (MAFLD).
Tue Sep 15 00:00:00 EDT 2020
The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching.
Immunity
Xu J,Zanvit P,Hu L,Tseng PY,Liu N,Wang F,Liu O,Zhang D,Jin W,Guo N,Han Y,Yin J,Cain A,Hoon MA,Wang S,Chen W
17-5791 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying itching associated with cutaneous wound healing, focusing on the contribution of soluble factors released during healing.
Tue Aug 18 00:00:00 EDT 2020
LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.
Gastroenterology
Gao Y,Yan Y,Tripathi S,Pentinmikko N,Amaral A,Päivinen P,Domènech-Moreno E,Andersson S,Wong IPL,Clevers H,Katajisto P,Mäkelä TP
17-5791 was used in Flow cytometry/Cell sorting to provide a connection between metabolism and the fate determination of ISCs.
Wed Apr 01 00:00:00 EDT 2020
Genetic Fate Mapping of Transient Cell Fate Reveals N-Cadherin Activity and Function in Tumor Metastasis.
Developmental cell
Li Y,Lv Z,Zhang S,Wang Z,He L,Tang M,Pu W,Zhao H,Zhang Z,Shi Q,Cai D,Wu M,Hu G,Lui KO,Feng J,Nieto MA,Zhou B
17-5791-82 was used in microwell chip assay to generate a genetic fate-mapping system for temporally seamless tracing of transient cell fate.
Mon Sep 14 00:00:00 EDT 2020
A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes.
Proceedings of the National Academy of Sciences of the United States of America
Wang L,Smith BA,Balanis NG,Tsai BL,Nguyen K,Cheng MW,Obusan MB,Esedebe FN,Patel SJ,Zhang H,Clark PM,Sisk AE,Said JW,Huang J,Graeber TG,Witte ON,Chin AI,Park JW
17-5791 was used in Flow cytometry/Cell sorting to reveal distinct molecular features of small cell carcinoma of the bladder and provide a transcriptional dataset and a preclinical model for further investigating SCCB biology.
Tue Jan 07 00:00:00 EST 2020
Transfer of metastatic traits via miR-200c in extracellular vesicles derived from colorectal cancer stem cells is inhibited by atractylenolide I.
Clinical and translational medicine
Tang D,Xu X,Ying J,Xie T,Cao G
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.
Development (Cambridge, England)
Sayols S,Klassek J,Werner C,Möckel S,Ritz S,Mendez-Lago M,Soshnikova N
17-5791 was used in Flow cytometry/Cell sorting to assess whether Axin2- and Lgr5-expressing cells are gastric progenitors in the developing mouse stomach.
Tue Sep 15 00:00:00 EDT 2020
Impact of a high‑fat diet on intestinal stem cells and epithelial barrier function in middle‑aged female mice.
Molecular medicine reports
Xie Y,Ding F,Di W,Lv Y,Xia F,Sheng Y,Yu J,Ding G
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
Smarcad1 mediates microbiota-induced inflammation in mouse and coordinates gene expression in the intestinal epithelium.
Genome biology
Kazakevych J,Denizot J,Liebert A,Portovedo M,Mosavie M,Jain P,Stellato C,Fraser C,Corrêa RO,Célestine M,Mattiuz R,Okkenhaug H,Miller JR,Vinolo MAR,Veldhoen M,Varga-Weisz P
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Wed Mar 11 00:00:00 EDT 2020
Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells.
Frontiers in immunology
Ko HJ,Hong SW,Verma R,Jung J,Lee M,Kim N,Kim D,Surh CD,Kim KS,Rudra D,Im SH
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Mon Apr 19 00:00:00 EDT 2021
Polyisocyanide Hydrogels as a Tunable Platform for Mammary Gland Organoid Formation.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Tang C,Span PN,Rowan AE,Aalders TW,Schalken JA,Adema GJ,Kouwer PHJ,Zegers MMP,Ansems M
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2020
Integrated Single-Cell Transcriptomics and Chromatin Accessibility Analysis Reveals Regulators of Mammary Epithelial Cell Identity.
Cell reports
Pervolarakis N,Nguyen QH,Williams J,Gong Y,Gutierrez G,Sun P,Jhutty D,Zheng GXY,Nemec CM,Dai X,Watanabe K,Kessenbrock K
17-5791-82 was used in Flow Cytometry to provide a resource to reveal cis/trans-regulatory elements associated with MEC identity and differentiation that will serve as a reference to determine how the chromatin accessibility landscape changes during breast cancer.
Tue Oct 20 00:00:00 EDT 2020
Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis.
JCI insight
Redente EF,Chakraborty S,Sajuthi S,Black BP,Edelman BL,Seibold MA,Riches DW
17-5791 was used in Flow cytometry/Cell sorting to test the hypothesis that the development of resistance to Fas-induced apoptosis by lung fibroblasts and myofibroblasts contibributes to their accumulation in the distal lung tissues of IPF patients.
Tue Dec 08 00:00:00 EST 2020
Bone metastasis is associated with acquisition of mesenchymal phenotype and immune suppression in a model of spontaneous breast cancer metastasis.
Scientific reports
Monteran L,Ershaid N,Sabah I,Fahoum I,Zait Y,Shani O,Cohen N,Eldar-Boock A,Satchi-Fainaro R,Erez N
17-5791 was used in Flow cytometry/Cell sorting to characterise the intrinsic changes in breast cancer cells that facilitate bone-tropism and found that they acquire mesenchymal and osteomimetic features.
Fri Aug 14 00:00:00 EDT 2020
TH17 cells require ongoing classic IL-6 receptor signaling to retain transcriptional and functional identity.
Science immunology
Harbour SN,DiToro DF,Witte SJ,Zindl CL,Gao M,Schoeb TR,Jones GW,Jones SA,Hatton RD,Weaver CT
17-5791-82 was used in Immunohistochemistry to find that IL-6 signaling is required for both induction and maintenance of mouse TH17 cells; IL-6Rα-deficient TH17 cells rapidly lost their TH17 phenotype and did not cause disease in two models of colitis.
Fri Jul 17 00:00:00 EDT 2020
Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs.
Cell stem cell
Velychko S,Adachi K,Kim KP,Hou Y,MacCarthy CM,Wu G,Schöler HR
17-5791 was used in Flow cytometry/Cell sorting to study the combinations fo reprogramming factors that can reprogram mouse somatic cells into induced pluripotent stem cells.
Thu Dec 05 00:00:00 EST 2019
Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs.
Cell stem cell
Velychko S,Adachi K,Kim KP,Hou Y,MacCarthy CM,Wu G,Schöler HR
17-5791 was used in Flow cytometry/Cell sorting to study the combinations fo reprogramming factors that can reprogram mouse somatic cells into induced pluripotent stem cells.
Thu Dec 05 00:00:00 EST 2019
PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism.
Cell stem cell
Stine RR,Sakers AP,TeSlaa T,Kissig M,Stine ZE,Kwon CW,Cheng L,Lim HW,Kaestner KH,Rabinowitz JD,Seale P
17-5791 was used in Flow cytometry/Cell sorting to identify how PRDM16 regulates intestinal metabolism and epithelial renewal in a region-specific way.
Thu Dec 05 00:00:00 EST 2019
Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells.
The Journal of experimental medicine
Chen HJ,Poran A,Unni AM,Huang SX,Elemento O,Snoeck HW,Varmus H
17-5791-82 was used in Flow Cytometry to demonstrate that inhibition of NOTCH signaling induces up to 10% of lung progenitor cells to form pulmonary neuroendocrine cells (PNECs), putative precursors to small cell lung cancers (SCLCs), and PNECs can be increased by reducing levels of retinoblastoma (RB) proteins with inhibitory RNA.
Mon Mar 04 00:00:00 EST 2019
The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor.
Disease models & mechanisms
Pfefferle AD,Darr DB,Calhoun BC,Mott KR,Rosen JM,Perou CM
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Jul 05 00:00:00 EDT 2019
Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury.
Cellular and molecular gastroenterology and hepatology
Jones JC,Brindley CD,Elder NH,Myers MG,Rajala MW,Dekaney CM,McNamee EN,Frey MR,Shroyer NF,Dempsey PJ
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Tue Jun 04 00:00:00 EDT 2019
Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium.
Nature communications
Wang J,Wang D,Chu K,Li W,Zeng YA
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Oct 31 00:00:00 EDT 2019
Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer.
Cancers
Erlangga Z,Wolff K,Poth T,Peltzer A,Nahnsen S,Spielberg S,Timrott K,Woller N,Kühnel F,Manns MP,Saborowski A,Vogel A,Saborowski M
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Nov 29 00:00:00 EST 2019
Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer In Vivo and In Vitro.
Hepatology communications
Saborowski A,Wolff K,Spielberg S,Beer B,Hartleben B,Erlangga Z,Becker D,Dow LE,Marhenke S,Woller N,Unger K,Schirmacher P,Manns MP,Marquardt JU,Vogel A,Saborowski M
17-5791 was used in Flow cytometry/Cell sorting to investigate cholangiocarcinoma pathophysiology and facilitate rapid functional annotation of putative cholangiocarcinoma driver and tumour maintenance genes.
Fri Mar 01 00:00:00 EST 2019
Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer In Vivo and In Vitro.
Hepatology communications
Saborowski A,Wolff K,Spielberg S,Beer B,Hartleben B,Erlangga Z,Becker D,Dow LE,Marhenke S,Woller N,Unger K,Schirmacher P,Manns MP,Marquardt JU,Vogel A,Saborowski M
17-5791 was used in Flow cytometry/Cell sorting to investigate cholangiocarcinoma pathophysiology and facilitate rapid functional annotation of putative cholangiocarcinoma driver and tumour maintenance genes.
Fri Mar 01 00:00:00 EST 2019
Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1.
eLife
Jen HI,Hill MC,Tao L,Sheng K,Cao W,Zhang H,Yu HV,Llamas J,Zong C,Martin JF,Segil N,Groves AK
17-5791-82 was used in Immunohistochemistry to offer a possible explanation for regenerative differences between sensory organs of the inner ear.
Mon Apr 29 00:00:00 EDT 2019
NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis.
Nature communications
Ershaid N,Sharon Y,Doron H,Raz Y,Shani O,Cohen N,Monteran L,Leider-Trejo L,Ben-Shmuel A,Yassin M,Gerlic M,Ben-Baruch A,Pasmanik-Chor M,Apte R,Erez N
17-5791-82 was used in Flow Cytometry to find that fibroblasts sense damage-associated molecular patterns (DAMPs), and in response activate the NLRP3 inflammasome pathway, resulting in instigation of pro-inflammatory signalling and secretion of IL-1β.
Thu Sep 26 00:00:00 EDT 2019
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor.
Nature
Zacharias WJ,Frank DB,Zepp JA,Morley MP,Alkhaleel FA,Kong J,Zhou S,Cantu E,Morrisey EE
17-5791 was used in Flow cytometry/Cell sorting to identify the AEP lineage as an evolutionarily conserved alveolar progenitor that represents a new target for human lung regeneration strategies.
Thu Mar 08 00:00:00 EST 2018
Lung epithelial cell-derived IL-25 negatively regulates LPS-induced exosome release from macrophages.
Military Medical Research
Li ZG,Scott MJ,Brzóska T,Sundd P,Li YH,Billiar TR,Wilson MA,Wang P,Fan J
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Mon Jul 30 00:00:00 EDT 2018
YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration.
Cell stem cell
Yui S,Azzolin L,Maimets M,Pedersen MT,Fordham RP,Hansen SL,Larsen HL,Guiu J,Alves MRP,Rundsten CF,Johansen JV,Li Y,Madsen CD,Nakamura T,Watanabe M,Nielsen OH,Schweiger PJ,Piccolo S,Jensen KB
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Jan 04 00:00:00 EST 2018
Integrin-Rac signalling for mammary epithelial stem cell self-renewal.
Breast cancer research : BCR
Olabi S,Ucar A,Brennan K,Streuli CH
17-5791 was used in Flow cytometry/Cell sorting to demonstrate that integrins are essential for the maintenance and self-renewal of mammary epithelial stem cells.
Mon Oct 22 00:00:00 EDT 2018
Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth.
Breast cancer research : BCR
Mao SPH,Park M,Cabrera RM,Christin JR,Karagiannis GS,Oktay MH,Zaiss DMW,Abrams SI,Guo W,Condeelis JS,Kenny PA,Segall JE
17-5791 was used in Flow cytometry/Cell sorting to study the association between amphiregulin expression and invasive papillary breast cancer development.
Fri Oct 26 00:00:00 EDT 2018
Zfat expression in ZsGreen reporter gene knock‑in mice: Implications for a novel function of Zfat in definitive erythropoiesis.
International journal of molecular medicine
Tsunoda T,Doi K,Ishikura S,Luo H,Nishi K,Matsuzaki H,Koyanagi M,Tanaka Y,Okamura T,Shirasawa S
17-5791-82 was used in Flow Cytometry to identify the expression and function of Zfat using ZsGreen signalling in the ZfatZsG/+ reporter mouse model.
Thu Nov 01 00:00:00 EDT 2018
Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells.
Nature communications
Lopes N,Charaix J,Cédile O,Sergé A,Irla M
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Molecular Characterization of Gastric Epithelial Cells Using Flow Cytometry.
International journal of molecular sciences
Bockerstett KA,Wong CF,Koehm S,Ford EL,DiPaolo RJ
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Apr 06 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases.
Frontiers in immunology
Glal D,Sudhakar JN,Lu HH,Liu MC,Chiang HY,Liu YC,Cheng CF,Shui JW
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Sep 26 00:00:00 EDT 2019
CD38 is methylated in prostate cancer and regulates extracellular NAD.
Cancer & metabolism
Mottahedeh J,Haffner MC,Grogan TR,Hashimoto T,Crowell PD,Beltran H,Sboner A,Bareja R,Esopi D,Isaacs WB,Yegnasubramanian S,Rettig MB,Elashoff DA,Platz EA,De Marzo AM,Teitell MA,Goldstein AS
17-5791 was used in Flow cytometry/Cell sorting to identify, in prostate cancer tissues, CD38 expression is epigenetically regulated through methylation and this controls the levels of extracellular NAD.
Mon Mar 21 00:00:00 EDT 2022
Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing.
Nature communications
Bartoschek M,Oskolkov N,Bocci M,Lövrot J,Larsson C,Sommarin M,Madsen CD,Lindgren D,Pekar G,Karlsson G,Ringnér M,Bergh J,Björklund Å,Pietras K
17-5791-82 was used in Immunohistochemistry to characterise three distinct subpopulations of cancer-associated fibroblasts in a mouse model of breast cancer.
Tue Dec 04 00:00:00 EST 2018
DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs.
Nature
Yamaji M,Jishage M,Meyer C,Suryawanshi H,Der E,Yamaji M,Garzia A,Morozov P,Manickavel S,McFarland HL,Roeder RG,Hafner M,Tuschl T
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Mar 23 00:00:00 EDT 2017
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.
Nature
Tammela T,Sanchez-Rivera FJ,Cetinbas NM,Wu K,Joshi NS,Helenius K,Park Y,Azimi R,Kerper NR,Wesselhoeft RA,Gu X,Schmidt L,Cornwall-Brady M,Yilmaz ÖH,Xue W,Katajisto P,Bhutkar A,Jacks T
17-5791 was used in Immunohistochemistry on frozen tissues to elucidate the presence of two distinct subpopulations of lung adenocarcinoma cells which drive proliferation and progression through Wnt signalling.
Thu May 18 00:00:00 EDT 2017
Epithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic.
Cell host & microbe
Entwistle LJ,Pelly VS,Coomes SM,Kannan Y,Perez-Lloret J,Czieso S,Silva Dos Santos M,MacRae JI,Collinson L,Sesay A,Nikolov N,Metidji A,Helmby H,Hui DY,Wilson MS
17-5791 was used in Flow cytometry/Cell sorting to uncover epithelial-cell-derived Pla2g1b as an essential mediator of helminth killing.
Wed Oct 11 00:00:00 EDT 2017
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer.
The Journal of experimental medicine
Öhlund D,Handly-Santana A,Biffi G,Elyada E,Almeida AS,Ponz-Sarvise M,Corbo V,Oni TE,Hearn SA,Lee EJ,Chio II,Hwang CI,Tiriac H,Baker LA,Engle DD,Feig C,Kultti A,Egeblad M,Fearon DT,Crawford JM,Clevers H,Park Y,Tuveson DA
17-5791 was used in Flow cytometry/Cell sorting to provide direct evidence for cancer-associated fibroblast heterogeneity in pancreatic cancer tumour biology, with implications for disease etiology and therapeutic development.
Mon Mar 06 00:00:00 EST 2017
The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis.
Genes & development
Herriges MJ,Tischfield DJ,Cui Z,Morley MP,Han Y,Babu A,Li S,Lu M,Cendan I,Garcia BA,Anderson SA,Morrisey EE
17-5791 was used in Chromatin immunoprecipitation to identify a feedback loop within the NANCI-Nkx2.1 gene duplex that is essential for buffering Nkx2.1 expression, lung epithelial cell identity, and tissue homeostasis.
Mon May 01 00:00:00 EDT 2017
Effects of Orally Ingested Arsenic on Respiratory Epithelial Permeability to Bacteria and Small Molecules in Mice.
Environmental health perspectives
Henderson MW,Madenspacher JH,Whitehead GS,Thomas SY,Aloor JJ,Gowdy KM,Fessler MB
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Sep 28 00:00:00 EDT 2017
FXYD5 Is an Essential Mediator of the Inflammatory Response during Lung Injury.
Frontiers in immunology
Brazee PL,Soni PN,Tokhtaeva E,Magnani N,Yemelyanov A,Perlman HR,Ridge KM,Sznajder JI,Vagin O,Dada LA
17-5791 was used in Flow cytometry/Cell sorting to confirm that FXYD5 induces a range of pro-inflammatory effects.
Fri Mar 18 00:00:00 EDT 2022
An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance.
Development (Cambridge, England)
Mohapatra B,Zutshi N,An W,Goetz B,Arya P,Bielecki TA,Mushtaq I,Storck MD,Meza JL,Band V,Band H
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Wed Mar 15 00:00:00 EDT 2017
ABCG1 regulates pulmonary surfactant metabolism in mice and men.
Journal of lipid research
de Aguiar Vallim TQ,Lee E,Merriott DJ,Goulbourne CN,Cheng J,Cheng A,Gonen A,Allen RM,Palladino END,Ford DA,Wang T,Baldán Á,Tarling EJ
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2017
The C-terminus domain of the hepatitis B virus x protein stimulates the proliferation of mouse foetal hepatic progenitor cells, although it is not required for the formation of spheroids.
International journal of molecular medicine
Yu L,Chen S,Luo N,He S
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Manipulation of Panx1 Activity Increases the Engraftment of Transplanted Lacrimal Gland Epithelial Progenitor Cells.
Investigative ophthalmology & visual science
Basova LV,Tang X,Umasume T,Gromova A,Zyrianova T,Shmushkovich T,Wolfson A,Hawley D,Zoukhri D,Shestopalov VI,Makarenkova HP
17-5791 was used in Flow cytometry/Cell sorting to show that blocking Panx1 and/or Casp4 activities is a beneficial strategy to enhance donor cell engraftment and lacrimal gland regeneration through the reduction of inflammation.
Wed Nov 01 00:00:00 EDT 2017
Reconstructing Lineage Hierarchies of Mouse Uterus Epithelial Development Using Single-Cell Analysis.
Stem cell reports
Wu B,An C,Li Y,Yin Z,Gong L,Li Z,Liu Y,Heng BC,Zhang D,Ouyang H,Zou X
17-5791 was used in Flow cytometry/Cell sorting to analyze the molecular and cellular mechanisms of uterine epithelial development by single-cell analysis.
Tue Jul 11 00:00:00 EDT 2017
Reconstructing Lineage Hierarchies of Mouse Uterus Epithelial Development Using Single-Cell Analysis.
Stem cell reports
Wu B,An C,Li Y,Yin Z,Gong L,Li Z,Liu Y,Heng BC,Zhang D,Ouyang H,Zou X
17-5791 was used in Flow cytometry/Cell sorting to analyze the molecular and cellular mechanisms of uterine epithelial development by single-cell analysis.
Tue Jul 11 00:00:00 EDT 2017
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Nature
Beyaz S,Mana MD,Roper J,Kedrin D,Saadatpour A,Hong SJ,Bauer-Rowe KE,Xifaras ME,Akkad A,Arias E,Pinello L,Katz Y,Shinagare S,Abu-Remaileh M,Mihaylova MM,Lamming DW,Dogum R,Guo G,Bell GW,Selig M,Nielsen GP,Gupta N,Ferrone CR,Deshpande V,Yuan GC,Orkin SH,Sabatini DM,Yilmaz ÖH
17-5791 was used in Flow cytometry/Cell sorting to demonstrate that a high-fat diet augments the numbers and proliferation of intestinal stem-cells.
Thu Mar 03 00:00:00 EST 2016
Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo.
Immunity
Lee CS,Penberthy KK,Wheeler KM,Juncadella IJ,Vandenabeele P,Lysiak JJ,Ravichandran KS
17-5791 was used in Immunohistochemistry to demonstrate that apoptotic cell clearance could be boosted in vivo, with potential to regulate tissue inflammation in specific contexts.
Tue Apr 19 00:00:00 EDT 2016
Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression.
Gut
Loyer X,Paradis V,Hénique C,Vion AC,Colnot N,Guerin CL,Devue C,On S,Scetbun J,Romain M,Paul JL,Rothenberg ME,Marcellin P,Durand F,Bedossa P,Prip-Buus C,Baugé E,Staels B,Boulanger CM,Tedgui A,Rautou PE
17579182 was used in flow cytometry to delineate the role of microRNA-21 in non-alcoholic steatohepatitis
Tue Nov 01 00:00:00 EDT 2016
Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria.
Mucosal immunology
Rios D,Wood MB,Li J,Chassaing B,Gewirtz AT,Williams IR
17-5791 was used in Immunofluorescence to demonstrate that M-cell-mediated sampling of commensal bacteria is a required initial step for efficient induction of intestinal SIgA.
Fri Jul 01 00:00:00 EDT 2016
Circulating tumor cell detection in hepatocellular carcinoma based on karyoplasmic ratios using imaging flow cytometry.
Scientific reports
Liu Z,Guo W,Zhang D,Pang Y,Shi J,Wan S,Cheng K,Wang J,Cheng S
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Dec 23 00:00:00 EST 2016
Regulation of Prostate Development and Benign Prostatic Hyperplasia by Autocrine Cholinergic Signaling via Maintaining the Epithelial Progenitor Cells in Proliferating Status.
Stem cell reports
Wang N,Dong BJ,Quan Y,Chen Q,Chu M,Xu J,Xue W,Huang YR,Yang R,Gao WQ
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Tue May 10 00:00:00 EDT 2016
Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals.
Stem cell reports
Maimets M,Rocchi C,Bron R,Pringle S,Kuipers J,Giepmans BN,Vries RG,Clevers H,de Haan G,van Os R,Coppes RP
17-5791 was used in Flow cytometry/Cell sorting to identify Wnt signalling as a key driver of self-renewal in adult SGSCs that allows extensive in vitro expansion and rescue of SG function in irradiated mice upon transplantation.
Tue Jan 12 00:00:00 EST 2016
LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration.
Nature communications
Shi Y,Wu W,Chai Q,Li Q,Hou Y,Xia H,Ren B,Xu H,Guo X,Jin C,Lv M,Wang Z,Fu YX,Zhu M
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2016
Telomere dysfunction in alveolar epithelial cells causes lung remodeling and fibrosis.
JCI insight
Naikawadi RP,Disayabutr S,Mallavia B,Donne ML,Green G,La JL,Rock JR,Looney MR,Wolters PJ
17-5791 was used in Flow cytometry/Cell sorting to investigate whether telomere dysfunction in type II alveolar epithelial cells, mediated by deletion of TRF1, leads to pulmonary fibrosis in mice.
Thu Sep 08 00:00:00 EDT 2016
Isolation of Highly Pure Primary Mouse Alveolar Epithelial Type II Cells by Flow Cytometric Cell Sorting.
Bio-protocol
Sinha M,Lowell CA
17-5791 was used in Flow cytometry/Cell sorting to describe an improved method for isolating highly pure and viable primary ATII cells from the lungs of naive mice.
Sun Nov 20 00:00:00 EST 2016
Parent stem cells can serve as niches for their daughter cells.
Nature
Pardo-Saganta A,Tata PR,Law BM,Saez B,Chow RD,Prabhu M,Gridley T,Rajagopal J
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Jul 30 00:00:00 EDT 2015
HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage-Associated Tumorigenesis.
Molecular cancer research : MCR
Janeckova L,Pospichalova V,Fafilek B,Vojtechova M,Tureckova J,Dobes J,Dubuissez M,Leprince D,Baloghova N,Horazna M,Hlavata A,Stancikova J,Sloncova E,Galuskova K,Strnad H,Korinek V
17-5791 was used in Flow cytometry/Cell sorting to show that the tumor-suppressive function of Hic1 in colon is related to its inhibitory action on proproliferative signaling mediated by the Tlr2 receptor present on tumor cells.
Wed Jul 01 00:00:00 EDT 2015
Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease.
Disease models & mechanisms
Williams BB,Tebbutt NC,Buchert M,Putoczki TL,Doggett K,Bao S,Johnstone CN,Masson F,Hollande F,Burgess AW,Scott AM,Ernst M,Heath JK
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2015
CARMA3 Is Critical for the Initiation of Allergic Airway Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Causton B,Ramadas RA,Cho JL,Jones K,Pardo-Saganta A,Rajagopal J,Xavier RJ,Medoff BD
17-5791 was used in Flow cytometry/Cell sorting to show that CARMA3 is a critical signalling molecule bridging the innate and adaptive immune responses in the lung.
Wed Jul 15 00:00:00 EDT 2015
Live fibroblast harvest reveals surface marker shift in vitro.
Tissue engineering. Part C, Methods
Walmsley GG,Rinkevich Y,Hu MS,Montoro DT,Lo DD,McArdle A,Maan ZN,Morrison SD,Duscher D,Whittam AJ,Wong VW,Weissman IL,Gurtner GC,Longaker MT
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Helicobacter pylori cag pathogenicity island's role in B7-H1 induction and immune evasion.
PloS one
Lina TT,Alzahrani S,House J,Yamaoka Y,Sharpe AH,Rampy BA,Pinchuk IV,Reyes VE
17-5791 was used in Flow cytometry/Cell sorting to investigate the underlying mechanisms and functional relevance of B7-H1 induction by Helicobacter pylori infection to chronic infection.
Thu Mar 03 00:00:00 EST 2016
Simplified protocol for flow cytometry analysis of fluorescently labeled exosomes and microvesicles using dedicated flow cytometer.
Journal of extracellular vesicles
Pospichalova V,Svoboda J,Dave Z,Kotrbova A,Kaiser K,Klemova D,Ilkovics L,Hampl A,Crha I,Jandakova E,Minar L,Weinberger V,Bryja V
17-5791 was used in Functional assays to demonstrate a novel approach for the quantification and characterisation of exosomes and microvesicles using a flow cytometer designed for small particles.
Thu Apr 02 00:00:00 EDT 2015
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Nature medicine
Clatworthy MR,Aronin CE,Mathews RJ,Morgan NY,Smith KG,Germain RN
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Nature medicine
Clatworthy MR,Aronin CE,Mathews RJ,Morgan NY,Smith KG,Germain RN
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Nature medicine
Clatworthy MR,Aronin CE,Mathews RJ,Morgan NY,Smith KG,Germain RN
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Mon Dec 01 00:00:00 EST 2014
Age-dependent enterocyte invasion and microcolony formation by Salmonella.
PLoS pathogens
Zhang K,Dupont A,Torow N,Gohde F,Leschner S,Lienenklaus S,Weiss S,Brinkmann MM,Kühnel M,Hensel M,Fulde M,Hornef MW
17-5791 was used in Flow cytometry/Cell sorting to provide important insight in the early steps of Salmonella infection in vivo.
Mon Sep 01 00:00:00 EDT 2014
An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells.
Journal of immunology (Baltimore, Md. : 1950)
White AJ,Jenkinson WE,Cowan JE,Parnell SM,Bacon A,Jones ND,Jenkinson EJ,Anderson G
17-5791 was used in Flow cytometry/Cell sorting to investigate whether thymus microenvironments are required in iNKT cell development, showing that medullary thymic epithelial cells are essential for intrathymic development of iNKT cells.
Sat Mar 15 00:00:00 EDT 2014
Dedifferentiation of committed epithelial cells into stem cells in vivo.
Nature
Tata PR,Mou H,Pardo-Saganta A,Zhao R,Prabhu M,Law BM,Vinarsky V,Cho JL,Breton S,Sahay A,Medoff BD,Rajagopal J
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Nov 14 00:00:00 EST 2013
Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.
Nature
Alenghat T,Osborne LC,Saenz SA,Kobuley D,Ziegler CG,Mullican SE,Choi I,Grunberg S,Sinha R,Wynosky-Dolfi M,Snyder A,Giacomin PR,Joyce KL,Hoang TB,Bewtra M,Brodsky IE,Sonnenberg GF,Bushman FD,Won KJ,Lazar MA,Artis D
17-5791 was used in Flow cytometry/Cell sorting to indicate that HDAC3 is critical in establishing normal host-commensal relationships and maintaining intestinal homeostasis.
Thu Dec 05 00:00:00 EST 2013
Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100.
Blood
Leonhardt F,Grundmann S,Behe M,Bluhm F,Dumont RA,Braun F,Fani M,Riesner K,Prinz G,Hechinger AK,Gerlach UV,Dierbach H,Penack O,Schmitt-Gräff A,Finke J,Weber WA,Zeiser R
17-5791-82 was used in Flow Cytometry to identify negative regulation of GvHD-related neovascularization by miR-100.
Thu Apr 25 00:00:00 EDT 2013
KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.
Cell stem cell
Goldman O,Han S,Sourisseau M,Dziedzic N,Hamou W,Corneo B,D'Souza S,Sato T,Kotton DN,Bissig KD,Kalir T,Jacobs A,Evans T,Evans MJ,Gouon-Evans V
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Jun 06 00:00:00 EDT 2013
Isolation, culture and genetic manipulation of mouse pancreatic ductal cells.
Nature protocols
Reichert M,Takano S,Heeg S,Bakir B,Botta GP,Rustgi AK
17-5791 was used in Flow cytometry/Cell sorting to describe a protocol for isolating mouse pancreatic ductal epithelial cells and ductlike cells, directly in vivo.
Tue Jan 14 00:00:00 EST 2014
Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors.
European journal of immunology
Baik S,Jenkinson EJ,Lane PJ,Anderson G,Jenkinson WE
17-5791 was used in Flow cytometry/Cell sorting to reveal an unexpected overlap in the phenotypic properties of bipotent TECs with their lineage-restricted counterparts.
Fri Mar 01 00:00:00 EST 2013
CagA-dependent downregulation of B7-H2 expression on gastric mucosa and inhibition of Th17 responses during Helicobacter pylori infection.
Journal of immunology (Baltimore, Md. : 1950)
Lina TT,Pinchuk IV,House J,Yamaoka Y,Graham DY,Beswick EJ,Reyes VE
17-5791 was used in Flow cytometry/Cell sorting to investigate the impact of H.pylori CagA on the modulation of the expression of the T cell costimulator B7-H2 by gastric epithelial cells.
Tue Oct 01 00:00:00 EDT 2013
A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology
Magness ST,Puthoff BJ,Crissey MA,Dunn J,Henning SJ,Houchen C,Kaddis JS,Kuo CJ,Li L,Lynch J,Martin MG,May R,Niland JC,Olack B,Qian D,Stelzner M,Swain JR,Wang F,Wang J,Wang X,Yan K,Yu J,Wong MH
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Tue Oct 15 00:00:00 EDT 2013
Culture of mouse amniotic fluid-derived cells on irradiated STO feeders results in the generation of primitive endoderm cell lines capable of self-renewal in vitro.
Cells, tissues, organs
Babic AM,Jang S,Nicolov E,Voicu H,Luckey CJ
17-5791 was used in Flow cytometry/Cell sorting to determine whether culture conditions that support self-renewal promote the generation of stable cell lines from amniotic fluid derived cells.
Tue Jun 24 00:00:00 EDT 2014
Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.
PloS one
El-Zaatari M,Kao JY,Tessier A,Bai L,Hayes MM,Fontaine C,Eaton KA,Merchant JL
17-5791 was used in Flow cytometry/Cell sorting to investigate the contribution of hedgehog signalling in gastric transformation, showing that Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets can be prevented by the deletion of Gli1.
Tue Sep 10 00:00:00 EDT 2013
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Nature
Yilmaz ÖH,Katajisto P,Lamming DW,Gültekin Y,Bauer-Rowe KE,Sengupta S,Birsoy K,Dursun A,Yilmaz VO,Selig M,Nielsen GP,Mino-Kenudson M,Zukerberg LR,Bhan AK,Deshpande V,Sabatini DM
17-5791 was used in Flow cytometry/Cell sorting to explore how Paneth cells augment stem-cell function in response to calorie restriction.
Thu Jun 28 00:00:00 EDT 2012
Fusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis.
Scientific reports
de Jong JH,Rodermond HM,Zimberlin CD,Lascano V,De Sousa E Melo F,Richel DJ,Medema JP,Vermeulen L
17-5791-82 was used in Flow cytometry/Cell sorting to demonstrate that intestinal epithelial homeostasis and regeneration is not dependent on cell fusion involving BMDCs.
Fri Apr 12 00:00:00 EDT 2013
Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.
Blood
Cook BD,Liu S,Evans T
Published figure using CD326 (EpCAM) monoclonal antibody (Product # 17-5791-82) in Flow Cytometry
Thu Jun 16 00:00:00 EDT 2011
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.jpg?time=20240507?time=20240507 "CD326 (EpCAM) Antibody (17-5791-82) in Flow")
.jpg?time=20240507?time=20240507 "CD326 (EpCAM) Antibody (17-5791-82) in Flow")
.jpg?time=20240507?time=20240507 "CD326 (EpCAM) Antibody (17-5791-82) in Flow")
