Product References
A single-cell transcriptional atlas reveals resident progenitor cell niche functions in TMJ disc development and injury.
Nature communications
Bi R,Yin Q,Li H,Yang X,Wang Y,Li Q,Fang H,Li P,Lyu P,Fan Y,Ying B,Zhu S
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2023
A cis-element at the Rorc locus regulates the development of type 3 innate lymphoid cells.
Frontiers in immunology
Chang D,Zhang H,Ge J,Xing Q,Guo X,Wang X,Dong C
25-0902-82 was used in Flow cytometry/Cell sorting to identify CNS9 as an essential cis-regulatory element controlling the lineage stability and plasticity of ILC3s through modulating expression levels of RORγt protein.
Tue Mar 28 00:00:00 EDT 2023
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition).
European journal of immunology
Cossarizza A,Chang HD,Radbruch A,Abrignani S,Addo R,Akdis M,Andrä I,Andreata F,Annunziato F,Arranz E,Bacher P,Bari S,Barnaba V,Barros-Martins J,Baumjohann D,Beccaria CG,Bernardo D,Boardman DA,Borger J,Böttcher C,Brockmann L,Burns M,Busch DH,Cameron G,Cammarata I,Cassotta A,Chang Y,Chirdo FG,Christakou E,Čičin-Šain L,Cook L,Corbett AJ,Cornelis R,Cosmi L,Davey MS,De Biasi S,De Simone G,Del Zotto G,Delacher M,Di Rosa F,Di Santo J,Diefenbach A,Dong J,Dörner T,Dress RJ,Dutertre CA,Eckle SBG,Eede P,Evrard M,Falk CS,Feuerer M,Fillatreau S,Fiz-Lopez A,Follo M,Foulds GA,Fröbel J,Gagliani N,Galletti G,Gangaev A,Garbi N,Garrote JA,Geginat J,Gherardin NA,Gibellini L,Ginhoux F,Godfrey DI,Gruarin P,Haftmann C,Hansmann L,Harpur CM,Hayday AC,Heine G,Hernández DC,Herrmann M,Hoelsken O,Huang Q,Huber S,Huber JE,Huehn J,Hundemer M,Hwang WYK,Iannacone M,Ivison SM,Jäck HM,Jani PK,Keller B,Kessler N,Ketelaars S,Knop L,Knopf J,Koay HF,Kobow K,Kriegsmann K,Kristyanto H,Krueger A,Kuehne JF,Kunze-Schumacher H,Kvistborg P,Kwok I,Latorre D,Lenz D,Levings MK,Lino AC,Liotta F,Long HM,Lugli E,MacDonald KN,Maggi L,Maini MK,Mair F,Manta C,Manz RA,Mashreghi MF,Mazzoni A,McCluskey J,Mei HE,Melchers F,Melzer S,Mielenz D,Monin L,Moretta L,Multhoff G,Muñoz LE,Muñoz-Ruiz M,Muscate F,Natalini A,Neumann K,Ng LG,Niedobitek A,Niemz J,Almeida LN,Notarbartolo S,Ostendorf L,Pallett LJ,Patel AA,Percin GI,Peruzzi G,Pinti M,Pockley AG,Pracht K,Prinz I,Pujol-Autonell I,Pulvirenti N,Quatrini L,Quinn KM,Radbruch H,Rhys H,Rodrigo MB,Romagnani C,Saggau C,Sakaguchi S,Sallusto F,Sanderink L,Sandrock I,Schauer C,Scheffold A,Scherer HU,Schiemann M,Schildberg FA,Schober K,Schoen J,Schuh W,Schüler T,Schulz AR,Schulz S,Schulze J,Simonetti S,Singh J,Sitnik KM,Stark R,Starossom S,Stehle C,Szelinski F,Tan L,Tarnok A,Tornack J,Tree TIM,van Beek JJP,van de Veen W,van Gisbergen K,Vasco C,Verheyden NA,von Borstel A,Ward-Hartstonge KA,Warnatz K,Waskow C,Wiedemann A,Wilharm A,Wing J,Wirz O,Wittner J,Yang JHM,Yang J
25-0902-82 was used in Flow cytometry/Cell sorting to provide the key aspects to consider when performing flow cytometry experiments.
Wed Dec 01 00:00:00 EST 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
Preservation of vision after CaMKII-mediated protection of retinal ganglion cells.
Cell
Guo X,Zhou J,Starr C,Mohns EJ,Li Y,Chen EP,Yoon Y,Kellner CP,Tanaka K,Wang H,Liu W,Pasquale LR,Demb JB,Crair MC,Chen B
25-0902-82 was used in Flow Cytometry to conclude that CaMKII reactivation protects long-distance RGC axon projections Flow Cytometry and preserves visual function, from the retina to the visual cortex, and visually guided behavior.
Thu Aug 05 00:00:00 EDT 2021
Reprogramming to recover youthful epigenetic information and restore vision.
Nature
Lu Y,Brommer B,Tian X,Krishnan A,Meer M,Wang C,Vera DL,Zeng Q,Yu D,Bonkowski MS,Yang JH,Zhou S,Hoffmann EM,Karg MM,Schultz MB,Kane AE,Davidsohn N,Korobkina E,Chwalek K,Rajman LA,Church GM,Hochedlinger K,Gladyshev VN,Horvath S,Levine ME,Gregory-Ksander MS,Ksander BR,He Z,Sinclair DA
25-0902-82 was used in Flow Cytometry to indicate that mammalian tissues retain a record of youthful epigenetic information-encoded in part by DNA methylation-that can be accessed to improve tissue function and promote regeneration in vivo.
Tue Dec 01 00:00:00 EST 2020
Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues.
Therapeutic advances in chronic disease
Zhang C,Gu X,Zhao G,Wang W,Shao J,Zhu J,Yuan T,Sun J,Nie D,Zhou Y
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Sun Apr 17 00:00:00 EDT 2022
Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis.
JCI insight
Redente EF,Chakraborty S,Sajuthi S,Black BP,Edelman BL,Seibold MA,Riches DW
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Tue Dec 08 00:00:00 EST 2020
Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells.
Cell reports
Morelli AE,Sumpter TL,Rojas-Canales DM,Bandyopadhyay M,Chen Z,Tkacheva O,Shufesky WJ,Wallace CT,Watkins SC,Berger A,Paige CJ,Falo LD,Larregina AT
25-0902 was used in Flow cytometry/Cell sorting to demonstrate an effect of the NK1R in T cells that is relevant for immunotherapies based on pro-inflammatory neuropeptides and its receptors.
Tue Mar 10 00:00:00 EDT 2020
Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells.
Cell reports
Morelli AE,Sumpter TL,Rojas-Canales DM,Bandyopadhyay M,Chen Z,Tkacheva O,Shufesky WJ,Wallace CT,Watkins SC,Berger A,Paige CJ,Falo LD,Larregina AT
25-0902 was used in Flow cytometry/Cell sorting to demonstrate an effect of the NK1R in T cells that is relevant for immunotherapies based on pro-inflammatory neuropeptides and its receptors.
Tue Mar 10 00:00:00 EDT 2020
Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age.
JCI insight
Wu R,Ma F,Tosevska A,Farrell C,Pellegrini M,Deb A
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Thu Dec 17 00:00:00 EST 2020
B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.
Nature communications
Wong JB,Hewitt SL,Heltemes-Harris LM,Mandal M,Johnson K,Rajewsky K,Koralov SB,Clark MR,Farrar MA,Skok JA
25-0902-82 was used in Flow Cytometry to show that in the fetal liver versus bone marrow environment, reduced IL-7R/STAT5 levels promote immunoglobulin kappa gene recombination at the early pro-B cell stage.
Fri Oct 18 00:00:00 EDT 2019
Intranasal delivery of adjuvant-free peptide nanofibers elicits resident CD8+ T cell responses.
Journal of controlled release : official journal of the Controlled Release Society
Si Y,Wen Y,Kelly SH,Chong AS,Collier JH
25-0902 was used in Flow cytometry/Cell sorting to investigate the extent to which self-assembled peptide nanofibers bearing an influenza peptide epitope elicit antigen-specific CD8+ T cell responses when delivered intranasally, and compare these responses with those elicited by subcutaneous immunization.
Sat Jul 28 00:00:00 EDT 2018
Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis.
The Journal of clinical investigation
Zang S,Li J,Yang H,Zeng H,Han W,Zhang J,Lee M,Moczygemba M,Isgandarova S,Yang Y,Zhou Y,Rao A,You MJ,Sun D,Huang Y
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2017
Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others.
Neuron
Norsworthy MW,Bei F,Kawaguchi R,Wang Q,Tran NM,Li Y,Brommer B,Zhang Y,Wang C,Sanes JR,Coppola G,He Z
25-0902 was used in Flow cytometry to demonstrate that Sox11 can reprogram adult retinal ganglion cells to a growth-competent state.
Wed Jun 21 00:00:00 EDT 2017
MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium.
PLoS pathogens
Friedrich C,Mamareli P,Thiemann S,Kruse F,Wang Z,Holzmann B,Strowig T,Sparwasser T,Lochner M
25-0902 was used in Flow cytometry/Cell sorting to suggest that MyD88 signaling in DC and IEC is both essential and sufficient to induce a full spectrum of host responses upon intestinal infection with C. rodentium.
Mon May 01 00:00:00 EDT 2017
Cross-Presentation of Soluble and Cell-Associated Antigen by Murine Hepatocytes Is Enhanced by Collectrin Expression.
Journal of immunology (Baltimore, Md. : 1950)
Dolina JS,Cechova S,Rudy CK,Sung SJ,Tang WW,Lee J,Hahn YS,Le TH
25-0902 was used in Flow cytometry/Cell sorting to identify the functional role of collectrin in the liver.
Wed Mar 15 00:00:00 EDT 2017
Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics.
Cell
Shekhar K,Lapan SW,Whitney IE,Tran NM,Macosko EZ,Kowalczyk M,Adiconis X,Levin JZ,Nemesh J,Goldman M,McCarroll SA,Cepko CL,Regev A,Sanes JR
25-0902 was used in Flow cytometry/Cell sorting to provide a systematic methodology for classifying neuronal types.
Thu Aug 25 00:00:00 EDT 2016
Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.
Annals of surgery
Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B
Thu Dec 01 00:00:00 EST 2016
Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation.
Mucosal immunology
Yang BH,Hagemann S,Mamareli P,Lauer U,Hoffmann U,Beckstette M,Föhse L,Prinz I,Pezoldt J,Suerbaum S,Sparwasser T,Hamann A,Floess S,Huehn J,Lochner M
25-0902 was used in Flow cytometry/Cell sorting to demonstrate that Foxp3(+) T cells expressing retinoic acid-related orphan receptor-γt, represent a stable regulatory T cell lineage with a highly suppressive phenotype in vivo.
Tue Mar 01 00:00:00 EST 2016
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation.
eLife
Pearson C,Thornton EE,McKenzie B,Schaupp AL,Huskens N,Griseri T,West N,Tung S,Seddon BP,Uhlig HH,Powrie F
25-0902 was used in Flow cytometry/Cell sorting to investigate how a small population of innate lymphoid cells (ILCs) has large effects on immune homeostasis, showing that ILC3s produce GM-CSF to orchestrate acute intestinal inflammation.
Mon Jan 18 00:00:00 EST 2016
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Inflammation rapidly reorganizes mouse bone marrow B cells and their environment in conjunction with early IgM responses.
Blood
Moreau JM,Berger A,Nelles ME,Mielnik M,Furlonger C,Cen SY,Besla R,Robbins CS,Paige CJ
25-0902 was used in Flow cytometry/Cell sorting to study the rapidity with which peripheral inflammation modifies the bone marrow compartment, and demonstrate that such modifications regulate acute IgM production within this organ.
Thu Sep 03 00:00:00 EDT 2015
Early virus-host interactions dictate the course of a persistent infection.
PLoS pathogens
Sullivan BM,Teijaro JR,de la Torre JC,Oldstone MB
25-0902 was used in Flow cytometry/Cell sorting to investigate the very early host-virus interactions that determine the establishment of viral persistence.
Thu Jan 01 00:00:00 EST 2015
BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints.
Developmental biology
Agarwal S,Loder SJ,Brownley C,Eboda O,Peterson JR,Hayano S,Wu B,Zhao B,Kaartinen V,Wong VC,Mishina Y,Levi B
25-0902 was used in Flow cytometry/Cell sorting to characterise a novel mouse model of heterotopic ossification.
Wed Apr 15 00:00:00 EDT 2015
Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice.
Nature communications
Singh NK,Kotla S,Dyukova E,Traylor JG,Orr AW,Chernoff J,Marion TN,Rao GN
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Wed Jun 24 00:00:00 EDT 2015
Depletion of STAT5 blocks TEL-SYK-induced APMF-type leukemia with myelofibrosis and myelodysplasia in mice.
Blood cancer journal
Sprissler C,Belenki D,Maurer H,Aumann K,Pfeifer D,Klein C,Müller TA,Kissel S,Hülsdünker J,Alexandrovski J,Brummer T,Jumaa H,Duyster J,Dierks C
25-0902 was used in Flow cytometry/Cell sorting to highlight the role of spleen tyrosine kinase (SYK) in acute myeloid leukaemia and myelofibrosis and prove SYK and STAT5 inhibitors as treatments for those diseases.
Fri Aug 22 00:00:00 EDT 2014
Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed states of human pluripotent stem cells.
Stem cell reports
Hough SR,Thornton M,Mason E,Mar JC,Wells CA,Pera MF
25-0902-82 was used in Flow cytometry/Cell sorting to study whether significant heterogeneity in gene expression is an inherent feature of the pluripotent state in stem cells.
Tue Jun 03 00:00:00 EDT 2014
Bispecificity for myelin and neuronal self-antigens is a common feature of CD4 T cells in C57BL/6 mice.
Journal of immunology (Baltimore, Md. : 1950)
Lucca LE,Desbois S,Ramadan A,Ben-Nun A,Eisenstein M,Carrié N,Guéry JC,Sette A,Nguyen P,Geiger TL,Mars LT,Liblau RS
25-0902 was used in Flow cytometry/Cell sorting to assess whether cross-reactivity is a common feature of the myelin oligodendrocyte glycoprotein epitope 35-55-specific T cell response.
Wed Oct 01 00:00:00 EDT 2014
Protective immunity against recurrent Staphylococcus aureus skin infection requires antibody and interleukin-17A.
Infection and immunity
Montgomery CP,Daniels M,Zhao F,Alegre ML,Chong AS,Daum RS
25-0902 was used in Flow cytometry/Cell sorting to develop an antibody and interlukin-17 combined vaccine which provides protective immunity against Staphylococcus aureus infections.
Thu May 01 00:00:00 EDT 2014
Genome-wide functional analysis reveals factors needed at the transition steps of induced reprogramming.
Cell reports
Yang CS,Chang KY,Rana TM
25-0902 was used in Flow cytometry/Cell sorting to identify the role of certain genes during transition steps during cellular reprogramming.
Thu Jul 24 00:00:00 EDT 2014
Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice.
Journal of immunology (Baltimore, Md. : 1950)
Hams E,Locksley RM,McKenzie AN,Fallon PG
25-0902 was used in Flow cytometry/Cell sorting to investigate the role of IL-25-responsive innate cells in regulating weight and glucose homeostasis.
Sun Dec 01 00:00:00 EST 2013
The RAG2 C-terminus and ATM protect genome integrity by controlling antigen receptor gene cleavage.
Nature communications
Chaumeil J,Micsinai M,Ntziachristos P,Roth DB,Aifantis I,Kluger Y,Deriano L,Skok JA
25-0902 was used in Flow cytometry/Cell sorting to reveal a direct mechanism for generating inter-locus rearrangements of antigen-receptor genes.
Thu Feb 27 00:00:00 EST 2014
Higher-order looping and nuclear organization of Tcra facilitate targeted rag cleavage and regulated rearrangement in recombination centers.
Cell reports
Chaumeil J,Micsinai M,Ntziachristos P,Deriano L,Wang JM,Ji Y,Nora EP,Rodesch MJ,Jeddeloh JA,Aifantis I,Kluger Y,Schatz DG,Skok JA
25-0902 was used in Flow cytometry/Cell sorting to show that higher-order loop formation is a deciding factor of directed RAG targeting and genome stability maintenance.
Thu Feb 21 00:00:00 EST 2013
Blockade of IL-10 signaling during bacillus Calmette-Guérin vaccination enhances and sustains Th1, Th17, and innate lymphoid IFN-γ and IL-17 responses and increases protection to Mycobacterium tuberculosis infection.
Journal of immunology (Baltimore, Md. : 1950)
Pitt JM,Stavropoulos E,Redford PS,Beebe AM,Bancroft GJ,Young DB,O'Garra A
25-0902 was used in Flow cytometry/Cell sorting to demonstrate that antagonists of IL-10 may be of great benefit as adjuvants in preventive vaccination against tuberculosis.
Mon Oct 15 00:00:00 EDT 2012
Partial characterization of the Sox2+ cell population in an adult murine model of digit amputation.
Tissue engineering. Part A
Agrawal V,Siu BF,Chao H,Hirschi KK,Raborn E,Johnson SA,Tottey S,Hurley KB,Medberry CJ,Badylak SF
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2012
Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation.
Immunity
Wuerzberger-Davis SM,Chen Y,Yang DT,Kearns JD,Bates PW,Lynch C,Ladell NC,Yu M,Podd A,Zeng H,Huang TT,Wen R,Hoffmann A,Wang D,Miyamoto S
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Fri Feb 25 00:00:00 EST 2011
Circulating herpes simplex type 1 (HSV-1)-specific CD8+ T cells do not access HSV-1 latently infected trigeminal ganglia.
Herpesviridae
Himmelein S,St Leger AJ,Knickelbein JE,Rowe A,Freeman ML,Hendricks RL
25-0902 was used in Flow cytometry/Cell sorting to evaluate the interactions between circulating Herpes Simplex Virus(HSV)-specific CD8 T memory cells and the latently HSV-infected trigeminal ganglia.
Tue Mar 15 00:00:00 EDT 2011
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
Blood
Schuman J,Chen Y,Podd A,Yu M,Liu HH,Wen R,Chen ZJ,Wang D
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Thu May 07 00:00:00 EDT 2009
Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production.
Blood
Qi Q,Xia M,Hu J,Hicks E,Iyer A,Xiong N,August A
25-0902 was used in Flow cytometry/Cell sorting to investigate the effect of Itk on T cell populations, showing that development of CD4+ gammadelta T cells is enhanced and IgE production is elevated in the absence of Itk.
Thu Jul 16 00:00:00 EDT 2009
Tracking epitope-specific T cells.
Nature protocols
Moon JJ,Chu HH,Hataye J,Pagán AJ,Pepper M,McLachlan JB,Zell T,Jenkins MK
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Tue Jun 30 00:00:00 EDT 2009
Trans-presentation of IL-15 by intestinal epithelial cells drives development of CD8alphaalpha IELs.
Journal of immunology (Baltimore, Md. : 1950)
Ma LJ,Acero LF,Zal T,Schluns KS
25-0902 was used in Flow cytometry/Cell sorting to identify the cell type responsible for the delivery of IL-15 to intraepithelial lymphocytes.
Wed Jul 15 00:00:00 EDT 2009
Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge.
Journal of immunology (Baltimore, Md. : 1950)
Hamada H,Garcia-Hernandez Mde L,Reome JB,Misra SK,Strutt TM,McKinstry KK,Cooper AM,Swain SL,Dutton RW
25-0902 was used in Flow cytometry/Cell sorting to study the role of Tc17 cells in influenza infection, showing that they protect against lethality.
Sun Mar 15 00:00:00 EDT 2009
Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge.
Journal of immunology (Baltimore, Md. : 1950)
Hamada H,Garcia-Hernandez Mde L,Reome JB,Misra SK,Strutt TM,McKinstry KK,Cooper AM,Swain SL,Dutton RW
25-0902 was used in Flow cytometry/Cell sorting to study the role of Tc17 cells in influenza infection, showing that they protect against lethality.
Sun Mar 15 00:00:00 EDT 2009
Manganese superoxide dismutase gene dosage affects chromosomal instability and tumor onset in a mouse model of T cell lymphoma.
Free radical biology & medicine
van de Wetering CI,Coleman MC,Spitz DR,Smith BJ,Knudson CM
Published figure using CD90.2 (Thy-1.2) monoclonal antibody (Product # 25-0902-82) in Flow Cytometry
Tue Apr 15 00:00:00 EDT 2008
