Product References
Landscape of mast cell populations across organs in mice and humans.
The Journal of experimental medicine
Tauber M,Basso L,Martin J,Bostan L,Pinto MM,Thierry GR,Houmadi R,Serhan N,Loste A,Blériot C,Kamphuis JBJ,Grujic M,Kjellén L,Pejler G,Paul C,Dong X,Galli SJ,Reber LL,Ginhoux F,Bajenoff M,Gentek R,Gaudenzio N
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 47-1172-82) in Flow Cytometry
Mon Oct 02 00:00:00 EDT 2023
FANCA deficiency promotes leukaemic progression by allowing the emergence of cells carrying oncogenic driver mutations.
Oncogene
Pawlikowska P,Delestré L,Gregoricchio S,Oppezzo A,Esposito M,Diop MB,Rosselli F,Guillouf C
47-1172-82 was used in Flow cytometry/Cell sorting to indicate that loss of the FANC pathway, known to control genetic instability, fosters the expansion of leukaemic cells carrying oncogenic mutations rather than mutation formation.
Fri Sep 01 00:00:00 EDT 2023
The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression.
Cell death & disease
Gentle IE,Moelter I,Badr MT,Döhner K,Lübbert M,Häcker G
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 47-1172-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling.
Cell reports
Agarwal P,Li H,Choi K,Hueneman K,He J,Welner RS,Starczynowski DT,Bhatia R
47-1172-82 was used in Flow Cytometry to find that TNF-α-mediated alterations in CML BM stromal niches enhance support of LSC maintenance and growth via CXCL1-CXCR2 signaling and that CXCR2 inhibition effectively depletes CML LSCs.
Tue Jul 13 00:00:00 EDT 2021
The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function.
Haematologica
Brown A,Schuetz D,Han Y,Daria D,Nattamai KJ,Eiwen K,Sakk V,Pospiech J,Saller T,van Zant G,Wagner W,Geiger H
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 47-1172-82) in Flow Cytometry
Tue Apr 27 00:00:00 EDT 2021
Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.
PLoS biology
Xiao J,Wang C,Yao JC,Alippe Y,Yang T,Kress D,Sun K,Kostecki KL,Monahan JB,Veis DJ,Abu-Amer Y,Link DC,Mbalaviele G
47-1172 was used in Flow cytometry/Cell sorting to test the hypothesis that lethal radiation damages tissues, thereby unleashing signals that indiscriminately activate the inflammasome pathways in host and transplanted cells.
Sat Aug 01 00:00:00 EDT 2020
Development of an inexpensive Raman-compatible substrate for the construction of a microarray screening platform.
The Analyst
Pastrana-Otero I,Majumdar S,Gilchrist AE,Gorman BL,Harley BAC,Kraft ML
47-1172-82 was used in Flow Cytometry to show that the spectra acquired from individual living cells on functionalized PA gels attached to our custom substrates were of sufficient quality to enable accurate identification of cell phenotypes using PLS-DA models of the cell spectra.
Mon Oct 26 00:00:00 EDT 2020
Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche.
Integrative biology : quantitative biosciences from nano to macro
Gilchrist AE,Harley BAC
47-1172-82 was used in Flow Cytometry to investigate the mechanism of how marrow-derived mesenchymal stromal and progenitor cells impacts hematopoietic stem cells fate decisions.
Fri Jul 10 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 47-1172-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.
Frontiers in pharmacology
Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 47-1172-82) in Flow Cytometry
Tue Feb 16 00:00:00 EST 2021
Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics.
eLife
Ricci B,Tycksen E,Celik H,Belle JI,Fontana F,Civitelli R,Faccio R
47-1172 was used in Flow cytometry/Cell sorting to find Osx transcript and Osx protein expression early during hematopoiesis, in subsets of hematopoietic stem cells and multipotent progenitor populations.
Wed Aug 05 00:00:00 EDT 2020
Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity.
Cell
Brown CC,Gudjonson H,Pritykin Y,Deep D,Lavallée VP,Mendoza A,Fromme R,Mazutis L,Ariyan C,Leslie C,Pe'er D,Rudensky AY
47-1172 was used in Flow cytometry/Cell sorting to identify two principal cDC2 lineages defined by distinct developmental pathways and transcriptional regulators, including T-bet and RORγt, two key transcription factors known to define innate and adaptive lymphocyte subsets.
Thu Oct 31 00:00:00 EDT 2019
Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.
Cell stem cell
Agarwal P,Isringhausen S,Li H,Paterson AJ,He J,Gomariz Á,Nagasawa T,Nombela-Arrieta C,Bhatia R
47-1172-82 was used in Flow Cytometry to highlight a critical role of niche-specific effects of Cxcl12 expression in maintaining quiescence of TKI-resistant LSC populations.
Thu May 02 00:00:00 EDT 2019
SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.
The Journal of clinical investigation
Abraham A,Qiu S,Chacko BK,Li H,Paterson A,He J,Agarwal P,Shah M,Welner R,Darley-Usmar VM,Bhatia R
47-1172 was used in Flow cytometry/Cell sorting to demonstrate an important role for SIRT1 in leukemia development.
Mon Jun 10 00:00:00 EDT 2019
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia.
Nature medicine
Zhang B,Nguyen LXT,Li L,Zhao D,Kumar B,Wu H,Lin A,Pellicano F,Hopcroft L,Su YL,Copland M,Holyoake TL,Kuo CJ,Bhatia R,Snyder DS,Ali H,Stein AS,Brewer C,Wang H,McDonald T,Swiderski P,Troadec E,Chen CC,Dorrance A,Pullarkat V,Yuan YC,Perrotti D,Carlesso N,Forman SJ,Kortylewski M,Kuo YH,Marcucci G
47-1172 was used in Flow cytometry/Cell sorting to demonstrate how bone marrow endothelial cells supply miR-126 to leukemia stem cells in chronic myelogenous leukemia which modulates their quiescence and self-renewal.
Tue May 01 00:00:00 EDT 2018
CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine.
Cell stem cell
Hirata Y,Furuhashi K,Ishii H,Li HW,Pinho S,Ding L,Robson SC,Frenette PS,Fujisaki J
47-1172-82 was used in Flow Cytometry to describe a Treg subpopulation that controls hematopoietic stem cell (HSC) quiescence and engraftment.
Thu Mar 01 00:00:00 EST 2018
The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development.
Immunity
Miyazaki M,Miyazaki K,Chen K,Jin Y,Turner J,Moore AJ,Saito R,Yoshida K,Ogawa S,Rodewald HR,Lin YC,Kawamoto H,Murre C
47-1172 was used in Flow cytometry/Cell sorting to propose that the E-Id protein axis specifies innate and adaptive lymphoid cell fate.
Tue May 16 00:00:00 EDT 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 47-1172-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Low Testosterone Alters the Activity of Mouse Prostate Stem Cells.
The Prostate
Zhou Y,Copeland B,Otto-Duessel M,He M,Markel S,Synold TW,Jones JO
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 47-1172-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2017
A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing.
Stem cell reports
Astuti Y,Kramer AC,Blake AL,Blazar BR,Tolar J,Taisto ME,Lund TC
47117282 was used in flow cytometry to report that ergosterol increases hematopoietic cell homing in zebrafish and mice
Tue Jan 10 00:00:00 EST 2017
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
Nature communications
Shirai CL,White BS,Tripathi M,Tapia R,Ley JN,Ndonwi M,Kim S,Shao J,Carver A,Saez B,Fulton RS,Fronick C,O'Laughlin M,Lagisetti C,Webb TR,Graubert TA,Walter MJ
Mon Jan 09 00:00:00 EST 2017
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML.
Cell
Puram RV,Kowalczyk MS,de Boer CG,Schneider RK,Miller PG,McConkey M,Tothova Z,Tejero H,Heckl D,Järås M,Chen MC,Li H,Tamayo A,Cowley GS,Rozenblatt-Rosen O,Al-Shahrour F,Regev A,Ebert BL
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 47-1172-82) in Flow Cytometry
Thu Apr 07 00:00:00 EDT 2016
Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAs.
Nature communications
Lai M,Gonzalez-Martin A,Cooper AB,Oda H,Jin HY,Shepherd J,He L,Zhu J,Nemazee D,Xiao C
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 47-1172-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Identification of a CD133-CD55- population functions as a fetal common skeletal progenitor.
Scientific reports
Weng L,Hu X,Kumar B,Garcia M,Todorov I,Jung X,Marcucci G,Forman SJ,Chen CC
47-1172 was used in Flow cytometry/Cell sorting to identify a CD133-CD55- population in the fetal skeletal element that can generate bone and bone marrow.
Thu Dec 08 00:00:00 EST 2016
Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors.
Development (Cambridge, England)
Karamitros D,Patmanidi AL,Kotantaki P,Potocnik AJ,Bähr-Ivacevic T,Benes V,Lygerou Z,Kioussis D,Taraviras S
47-1172 was used in Flow cytometry/Cell sorting to investigate the role of geminin in hematopoiesis.
Thu Jan 01 00:00:00 EST 2015
Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs.
PLoS pathogens
Ebert S,Becker M,Lemmermann NA,Büttner JK,Michel A,Taube C,Podlech J,Böhm V,Freitag K,Thomas D,Holtappels R,Reddehase MJ,Stassen M
47-1172 was used in Flow cytometry/Cell sorting to explore the role of mast cells in the recruitment of protective CD8 T cells to the lungs during systemic infection.
Tue Apr 01 00:00:00 EDT 2014
TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis.
Journal of immunology (Baltimore, Md. : 1950)
Oh MH,Oh SY,Lu J,Lou H,Myers AC,Zhu Z,Zheng T
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 47-1172-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2013
Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat β-thalassemia.
Molecular therapy : the journal of the American Society of Gene Therapy
Ronen K,Negre O,Roth S,Colomb C,Malani N,Denaro M,Brady T,Fusil F,Gillet-Legrand B,Hehir K,Beuzard Y,Leboulch P,Down JD,Payen E,Bushman FD
47-1172 was used in Flow cytometry/Cell sorting to study integration sites of a lentiviral vector encoding β-globin during treatment of β-thalassemia, showing that integration occurred multiple times and clonal populations with integration near growth-control genes were not enriched.
Fri Jul 01 00:00:00 EDT 2011