Product References
Single-cell RNA-seq analysis reveals dual sensing of HIV-1 in blood Axl+ dendritic cells.
iScience
Brouiller F,Nadalin F,Bonté PE,Ait-Mohamed O,Delaugerre C,Lelièvre JD,Ginhoux F,Ruffin N,Benaroch P
47-9956-42 was used in flow cytometry to demonstrate that HIV-1 induced two main broad and intense transcriptional programs in different Axl+DCs potentially induced by different sensors; an NF-κB-mediated program that led to DC maturation and efficient CD4+ T cell activation, and a program mediated by STAT1/2 that activated type I IFN and ISG responses.
Fri Feb 17 00:00:00 EST 2023
PD-L1 blockade restores CAR T cell activity through IFN-γ-regulation of CD163+ M2 macrophages.
Journal for immunotherapy of cancer
Yamaguchi Y,Gibson J,Ou K,Lopez LS,Ng RH,Leggett N,Jonsson VD,Zarif JC,Lee PP,Wang X,Martinez C,Dorff TB,Forman SJ,Priceman SJ
47-9956-42 was used in Flow cytometry/Cell sorting to reveal an alternative mechanism by which the combination of CAR T cells and immune checkpoint blockade modulates the immune landscape of solid tumors to enhance therapeutic efficacy of CAR T cells.
Wed Jun 01 00:00:00 EDT 2022
GM-CSF-activated human dendritic cells promote type 1 T follicular helper cell polarization in a CD40-dependent manner.
Journal of cell science
Korniotis S,Saichi M,Trichot C,Hoffmann C,Amblard E,Viguier A,Grondin S,Noel F,Mattoo H,Soumelis V
47-9956-42 was used in Flow cytometry/Cell sorting to report that human blood CD1c+ dendritic cells activated by GM-CSF (also known as CSF2) drive the differentiation of naive CD4+ T cells into Tfh1 cells.
Tue Nov 01 00:00:00 EDT 2022
Activated CD4+ T cells and CD14hiCD16+ monocytes correlate with antibody response following influenza virus infection in humans.
Cell reports. Medicine
Wong SS,Oshansky CM,Guo XJ,Ralston J,Wood T,Reynolds GE,Seeds R,Jelley L,Waite B,Jeevan T,Zanin M,Widdowson MA,Huang QS,Thomas PG,Webby RJ
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Tue Apr 20 00:00:00 EDT 2021
The role of irreversible electroporation in promoting M1 macrophage polarization via regulating the HMGB1-RAGE-MAPK axis in pancreatic cancer.
Oncoimmunology
He C,Sun S,Zhang Y,Xie F,Li S
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Thu Mar 11 00:00:00 EST 2021
Transplantation of human amniotic epithelial cells promotes morphological and functional regeneration in a rat uterine scar model.
Stem cell research & therapy
Fan Y,Sun J,Zhang Q,Lai D
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Wed Mar 24 00:00:00 EDT 2021
Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection.
Cell reports. Medicine
Rouers A,Chng MHY,Lee B,Rajapakse MP,Kaur K,Toh YX,Sathiakumar D,Loy T,Thein TL,Lim VWX,Singhal A,Yeo TW,Leo YS,Vora KA,Casimiro D,Lim B,Tucker-Kellogg L,Rivino L,Newell EW,Fink K
47-9956-42 was used in Flow Cytometry to reveal associations between cellular profiles and disease severity, opening opportunities to study immunopathology in dengue disease and the potential predictive value of these parameters.
Tue May 18 00:00:00 EDT 2021
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease.
Cell
Lee JY,Hall JA,Kroehling L,Wu L,Najar T,Nguyen HH,Lin WY,Yeung ST,Silva HM,Li D,Hine A,Loke P,Hudesman D,Martin JC,Kenigsberg E,Merad M,Khanna KM,Littman DR
47-9956 was used in Flow cytometry/Cell sorting to suggest that serum amyloid A proteins direct a pathogenic pro-inflammatory Th17 cell differentiation program and promote Th17-mediated inflammatory diseases.
Thu Jan 09 00:00:00 EST 2020
Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells.
Immunity
Bourdely P,Anselmi G,Vaivode K,Ramos RN,Missolo-Koussou Y,Hidalgo S,Tosselo J,Nuñez N,Richer W,Vincent-Salomon A,Saxena A,Wood K,Lladser A,Piaggio E,Helft J,Guermonprez P
47-9956-42 was used in Flow Cytometry to define DC3s as a lineage of inflammatory DCs endowed with a strong potential to regulate tumor immunity.
Tue Aug 18 00:00:00 EDT 2020
Lung transplantation for patients with severe COVID-19.
Science translational medicine
Bharat A,Querrey M,Markov NS,Kim S,Kurihara C,Garza-Castillon R,Manerikar A,Shilatifard A,Tomic R,Politanska Y,Abdala-Valencia H,Yeldandi AV,Lomasney JW,Misharin AV,Budinger GRS
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research
Kwon M,Kim CG,Lee H,Cho H,Kim Y,Lee EC,Choi SJ,Park J,Seo IH,Bogen B,Song IC,Jo DY,Kim JS,Park SH,Choi I,Choi YS,Shin EC
47-9956 was used in Flow cytometry/Cell sorting to indicate that combined blockade of PD-1 and TGFβ may be useful for the treatment of multiple myeloma.
Wed Apr 01 00:00:00 EDT 2020
Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation.
PLoS pathogens
Oliveira AER,Pereira MCA,Belew AT,Ferreira LRP,Pereira LMN,Neves EGA,Nunes MDCP,Burleigh BA,Dutra WO,El-Sayed NM,Gazzinelli RT,Teixeira SMR
47-9956 was used in Flow cytometry/Cell sorting to analyze changes in the expression of host genes during in vitro infection of HFF cells with the CL Brener and CL-14 strains by analyzing total RNA extracted from cells at 60 and 96 hours post-infection (hpi) with each strain, as well as from uninfected cells.
Sat Aug 01 00:00:00 EDT 2020
Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation.
PLoS pathogens
Oliveira AER,Pereira MCA,Belew AT,Ferreira LRP,Pereira LMN,Neves EGA,Nunes MDCP,Burleigh BA,Dutra WO,El-Sayed NM,Gazzinelli RT,Teixeira SMR
47-9956 was used in Flow cytometry/Cell sorting to analyze changes in the expression of host genes during in vitro infection of HFF cells with the CL Brener and CL-14 strains by analyzing total RNA extracted from cells at 60 and 96 hours post-infection (hpi) with each strain, as well as from uninfected cells.
Sat Aug 01 00:00:00 EDT 2020
PF-127 hydrogel plus sodium ascorbyl phosphate improves Wharton's jelly mesenchymal stem cell-mediated skin wound healing in mice.
Stem cell research & therapy
Deng Q,Huang S,Wen J,Jiao Y,Su X,Shi G,Huang J
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Fri Apr 03 00:00:00 EDT 2020
Characterization of HLA-G Regulation and HLA Expression in Breast Cancer and Malignant Melanoma Cell Lines upon IFN-γ Stimulation and Inhibition of DNA Methylation.
International journal of molecular sciences
Jørgensen N,Sayed A,Jeppesen HB,Persson G,Weisdorf I,Funck T,Hviid TVF
47-9956 was used in Flow cytometry/Cell sorting to explore the expression of human leukocyte antigen-G in breast cancer and malignant melanoma cell lines.
Wed Jun 17 00:00:00 EDT 2020
Characterization of HLA-G Regulation and HLA Expression in Breast Cancer and Malignant Melanoma Cell Lines upon IFN-γ Stimulation and Inhibition of DNA Methylation.
International journal of molecular sciences
Jørgensen N,Sayed A,Jeppesen HB,Persson G,Weisdorf I,Funck T,Hviid TVF
47-9956 was used in Flow cytometry/Cell sorting to explore the expression of human leukocyte antigen-G in breast cancer and malignant melanoma cell lines.
Wed Jun 17 00:00:00 EDT 2020
Connecting METTL3 and intratumoural CD33+ MDSCs in predicting clinical outcome in cervical cancer.
Journal of translational medicine
Ni HH,Zhang L,Huang H,Dai SQ,Li J
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Thu Oct 15 00:00:00 EDT 2020
New GMP manufacturing processes to obtain thermostable HIV-1 gp41 virosomes under solid forms for various mucosal vaccination routes.
NPJ vaccines
Amacker M,Smardon C,Mason L,Sorrell J,Jeffery K,Adler M,Bhoelan F,Belova O,Spengler M,Punnamoottil B,Schwaller M,Bonduelle O,Combadière B,Stegmann T,Naylor A,Johnson R,Wong D,Fleury S
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Fri Dec 17 00:00:00 EST 2021
Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantation.
Nature communications
Esfahani K,Al-Aubodah TA,Thebault P,Lapointe R,Hudson M,Johnson NA,Baran D,Bhulaiga N,Takano T,Cailhier JF,Piccirillo CA,Miller WH
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Thu Oct 17 00:00:00 EDT 2019
Plasmacytoid dendritic cell and myeloid dendritic cell function in ageing: A comparison between elderly and young adult women.
PloS one
Splunter MV,Perdijk O,Fick-Brinkhof H,Floris-Vollenbroek EG,Meijer B,Brugman S,Savelkoul HFJ,van Hoffen E,Joost van Neerven RJ
47-9956 was used in Flow cytometry/Cell sorting to confirm and extend the knowledge about immunosenescence and inflammageing on innate immunity in elderly women.
Wed Mar 25 00:00:00 EDT 2020
Age-Dependent Pre-Vaccination Immunity Affects the Immunogenicity of Varicella Zoster Vaccination in Middle-aged Adults.
Frontiers in immunology
van der Heiden M,de Rond LGH,van Zelm MC,Berbers GAM,Boots AMH,Buisman AM
47-9956 was used in Flow cytometry/Cell sorting to investigate the immune response after vaccination with Zostavax consisting of live-attenuated Varicella zoster virus.
Thu Feb 14 00:00:00 EST 2019
Comprehensive characterization of chorionic villi-derived mesenchymal stromal cells from human placenta.
Stem cell research & therapy
Ventura Ferreira MS,Bienert M,Müller K,Rath B,Goecke T,Opländer C,Braunschweig T,Mela P,Brümmendorf TH,Beier F,Neuss S
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Mon Feb 05 00:00:00 EST 2018
Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity.
Cell reports
Balan S,Arnold-Schrauf C,Abbas A,Couespel N,Savoret J,Imperatore F,Villani AC,Vu Manh TP,Bhardwaj N,Dalod M
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Tue Aug 14 00:00:00 EDT 2018
Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators.
Cell reports
Lagou V,Garcia-Perez JE,Smets I,Van Horebeek L,Vandebergh M,Chen L,Mallants K,Prezzemolo T,Hilven K,Humblet-Baron S,Moisse M,Van Damme P,Boeckxstaens G,Bowness P,Dubois B,Dooley J,Liston A,Goris A
47-9956-42 was used in Flow Cytometry to identify eight genome-wide significant associations explaining 6%-20% of variance in immune system regulation.
Tue Oct 16 00:00:00 EDT 2018
Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway.
Nature communications
Tang-Huau TL,Gueguen P,Goudot C,Durand M,Bohec M,Baulande S,Pasquier B,Amigorena S,Segura E
47-9956 was used in Flow cytometry/Cell sorting to demonstrate that human monocyte-derived cells cross-present exclusively using a vacuolar pathway.
Mon Jul 02 00:00:00 EDT 2018
Bovine Lactoferrin Enhances TLR7-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D.
Frontiers in immunology
van Splunter M,Perdijk O,Fick-Brinkhof H,Feitsma AL,Floris-Vollenbroek EG,Meijer B,Brugman S,Savelkoul HFJ,van Hoffen E,van Neerven RJJ
47-9956 was used in Flow cytometry/Cell sorting to investigate the potential to restore Toll like receptor responsiveness of plasmacytoid dendritic cells and myeloid dendritic cells, and to reduce inflammatory markers in serum.
Wed Oct 02 00:00:00 EDT 2019
Bovine Lactoferrin Modulates Dendritic Cell Differentiation and Function.
Nutrients
Perdijk O,van Neerven RJJ,van den Brink E,Savelkoul HFJ,Brugman S
47-9956 was used in Flow cytometry/Cell sorting to demonstrate that lactoferrin alters dendritic cells differentiation and dampens responsiveness towards TLR ligands.
Fri Jun 29 00:00:00 EDT 2018
Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages.
Immunity
Goudot C,Coillard A,Villani AC,Gueguen P,Cros A,Sarkizova S,Tang-Huau TL,Bohec M,Baulande S,Hacohen N,Amigorena S,Segura E
47-9956 was used in Flow cytometry/Cell sorting to elucidate the role of the aryl hydrocarbon receptor as a molecular switch for monocyte fate specification in response to micro-environmental factors.
Tue Sep 19 00:00:00 EDT 2017
HDAC inhibition potentiates immunotherapy in triple negative breast cancer.
Oncotarget
Terranova-Barberio M,Thomas S,Ali N,Pawlowska N,Park J,Krings G,Rosenblum MD,Budillon A,Munster PN
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Tue Dec 26 00:00:00 EST 2017
Gut-homing Δ42PD1+Vδ2 T cells promote innate mucosal damage via TLR4 during acute HIV type 1 infection.
Nature microbiology
Cheung AKL,Kwok HY,Huang Y,Chen M,Mo Y,Wu X,Lam KS,Kong HK,Lau TCK,Zhou J,Li J,Cheng L,Kiat Lee B,Peng Q,Lu X,An M,Wang H,Shang H,Zhou B,Wu H,Xu A,Yuen KY,Chen Z
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens.
Oncotarget
Pathangey LB,McCurry DB,Gendler SJ,Dominguez AL,Gorman JE,Pathangey G,Mihalik LA,Dang Y,Disis ML,Cohen PA
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Tue Feb 14 00:00:00 EST 2017
Azacytidine prevents experimental xenogeneic graft-versus-host disease without abrogating graft-versus-leukemia effects.
Oncoimmunology
Ehx G,Fransolet G,de Leval L,D'Hondt S,Lucas S,Hannon M,Delens L,Dubois S,Drion P,Beguin Y,Humblet-Baron S,Baron F
47-9956 was used in Flow cytometry/Cell sorting to investigate the impact of 5-azacytidine on xenogeneic graft-vs.-host disease and graft-vs.-leukaemia effects in a humanised murine model of transplantation.
Tue Jan 12 00:00:00 EST 2021
FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas.
Leukemia
Brown PJ,Wong KK,Felce SL,Lyne L,Spearman H,Soilleux EJ,Pedersen LM,Møller MB,Green TM,Gascoyne DM,Banham AH
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors.
Stem cell reports
Sugita S,Iwasaki Y,Makabe K,Kimura T,Futagami T,Suegami S,Takahashi M
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Tue Oct 11 00:00:00 EDT 2016
MIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia.
Stem cell reports
Yao Y,Deng Q,Song W,Zhang H,Li Y,Yang Y,Fan X,Liu M,Shang J,Sun C,Tang Y,Jin X,Liu H,Huang B,Zhou Y
Published figure using HLA-DR monoclonal antibody (Product # 47-9956-42) in Flow Cytometry
Tue Aug 09 00:00:00 EDT 2016
A subset of circulating blood mycobacteria-specific CD4 T cells can predict the time to Mycobacterium tuberculosis sputum culture conversion.
PloS one
Riou C,Gray CM,Lugongolo M,Gwala T,Kiravu A,Deniso P,Stewart-Isherwood L,Omar SV,Grobusch MP,Coetzee G,Conradie F,Ismail N,Kaplan G,Fallows D
47-9956 was used in Flow cytometry/Cell sorting to investigate 18 HIV-negative patients with MDR-TB for M. tuberculosis (Mtb)- and PPD-specific CD4 T cell responses and followed them over 6 months of drug therapy.
Tue Apr 07 00:00:00 EDT 2015
Transcriptional specialization of human dendritic cell subsets in response to microbial vaccines.
Nature communications
Banchereau R,Baldwin N,Cepika AM,Athale S,Xue Y,Yu CI,Metang P,Cheruku A,Berthier I,Gayet I,Wang Y,Ohouo M,Snipes L,Xu H,Obermoser G,Blankenship D,Oh S,Ramilo O,Chaussabel D,Banchereau J,Palucka K,Pascual V
47-9956 was used in Flow cytometry/Cell sorting to describe the transcriptional programs induced in human DCs by pathogens, innate receptor ligands and vaccines.
Wed Oct 22 00:00:00 EDT 2014