Invitrogen

CD34 Monoclonal Antibody (RAM34), eFluor™ 450, eBioscience™

Advanced Verification

This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.

89 Published Figures

111 References

View all (163) CD34 antibodies

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FIGURE: 1 / 91

CD34 Antibody (48-0341-82) in Flow

Staining of C57BL/6 bone marrow cells with Anti-Mouse Hematopoietic Lineage antibodies FITC and 1 µg of Rat IgG2a kappa Isotype Control eFluor® 450 (Product # 48-4321-82) (left) or 1 µg of Anti-Mouse CD34 eFluor® 450 (right). Total viable cells were used for analysis.

CD34 Antibody in Immunocytochemistry (ICC/IF)

CD34 Antibody in Immunocytochemistry, Flow Cytometry (ICC/IF, Flow)

CD34 Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)

CD34 Antibody in Immunohistochemistry (Frozen) (IHC (F))

CD34 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

CD34 Antibody — Figure 3 Inhibition of monocyte to macrophage maturation leads to a decrease in VM macrophages. ( A-D ) Mice with sc matrigel plugs were treated with the c-Fms tyrosine kinase inhibitor Ki20227, a drug that blocks monocyte to macrophage maturation. Seven days post matrigel injection, mice were euthanized, plugs harvested, cells isolated from subcutaneous plugs, immunolabeled with antibodies against F4/80, CD31, CD34 and CD133 and subjected to flow cytometry. ( A ) Ki20227 decreases F4/80 + macrophages by 67%. ( B ) F4/80 + , CD31 + population decreases by 62%. ( C ) F4/80 - , CD31 + population doubled in response to Ki treatment. ( D ) Ki treatment led to a 61% decrease in the F4/80 + , CD34 + , CD133 + population. This figure represents one experiment with an N = 4-5 mice per group, flow data shown for one plug isolate and significance indicated above each bar graph. Experiment was repeated 2 times with similar results. {TM}

Product Details

48-0341-82

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

View 17 publications 17 publications

Immunohistochemistry (Frozen) (IHC (F))

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

View 10 publications 10 publications

Flow Cytometry (Flow)

1 µg/test

View 80 publications 80 publications

Product Specifications

Species Reactivity

Mouse

Published species

Goat, Hamster, Human, Mouse

Host/Isotype

Rat / IgG2a, kappa

Recommended Isotype Control

Rat IgG2a kappa Isotype Control (eBR2a), eFluor™ 450, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

RAM34

Conjugate

eFluor™ 450 eFluor™ 450 eFluor™ 450

Excitation/Emission Max

405/445 nm View spectra

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2043837

Product Specific Information

Description: The RAM34 monoclonal antibody reacts with mouse CD34, also known as mucosialin. It has been reported that the RAM34 antibody can be used to detect CD34+Sca-1+c-Kit+ cells. CD34 is a highly glycosylated (approximately 90-120 kDa) member of the sialomucin family and is expressed by capillary endothelial cells, bone marrow stroma, and a small subpopulation of mouse bone marrow cells. RAM34 has been used to purify mouse hematopoietic stem cells (HSC) to near homogeneity. CD34 expressed on endothelial cells is a ligand for CD62L and plays a role in adhesion. Simultaneous staining of mouse bone marrow cells with a cocktail of antibodies to lineage markers (CD3, CD11b, Ly6G, TER-119 and CD45R/B220) reveals a subset of cells that stain with the RAM34 antibody and express undetectable to low levels of the indicated lineage markers.

Applications Reported: This RAM34 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This RAM34 antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Note: When staining with the RAM34 antibody an incubation time of 90 minutes is recommended to obtain the optimal signal to noise ratio.

For more detailed information on staining with RAM34, please refer to Ema et al., listed under References.

eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome.

Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

CD34 is a highly glycosylated monomeric with a molecular weight range of 111-115 kDa surface protein that is present on many stem cell populations. CD34 is a stem cell marker although its expression on human hematopoietic stem cells is reversible. CD34 may serve as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions. CD34 is possibly an adhesion molecule with a putative role for mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Further, CD34 could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Product References

STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.

International journal of molecular sciences

Li N,Wang Y,Wang A,Zhang J,Jia C,Yu C,Song Z,Wang S,Liu L,Yi J,Bao Y,Huang Y,Sun L

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Feb 03 00:00:00 EST 2023

Hematopoietic Cell Autonomous Disruption of Hematopoiesis in a Germline Loss-of-function Mouse Model of RUNX1-FPD.

HemaSphere

Ernst MPT,Pronk E,van Dijk C,van Strien PMH,van Tienhoven TVD,Wevers MJW,Sanders MA,Bindels EMJ,Speck NA,Raaijmakers MHGP

48-0341-82 was used in Flow cytometry/Cell sorting to study mice harboring a germline hypomorphic mutation of one Runx1 allele with a loss-of-function mutation in the other Runx1 allele (Runx1 L148A/- mice), which display many hematologic characteristics found in human RUNX1-FPD patients.

Wed Feb 01 00:00:00 EST 2023

Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs.

Cell

Tarazi S,Aguilera-Castrejon A,Joubran C,Ghanem N,Ashouokhi S,Roncato F,Wildschutz E,Haddad M,Oldak B,Gomez-Cesar E,Livnat N,Viukov S,Lokshtanov D,Naveh-Tassa S,Rose M,Hanna S,Raanan C,Brenner O,Kedmi M,Keren-Shaul H,Lapidot T,Maza I,Novershtern N,Hanna JH

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2022

Hyaline cartilage differentiation of fibroblasts in regeneration and regenerative medicine.

Development (Cambridge, England)

Yu L,Lin YL,Yan M,Li T,Wu EY,Zimmel K,Qureshi O,Falck A,Sherman KM,Huggins SS,Hurtado DO,Suva LJ,Gaddy D,Cai J,Brunauer R,Dawson LA,Muneoka K

48-0341-82 was used in Flow Cytometry to identify fibroblasts as a novel source for hyaline cartilage regeneration, and BMP9 as a potent inducer of hyaline and articular chondrocyte differentiation.

Sat Jan 15 00:00:00 EST 2022

Multiple benign fibrous histiocytomas of the mandible: A case report and review of the literature.

Experimental and therapeutic medicine

Wang Y,Huang Y,Cai WX,Tao Q

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Thu Sep 01 00:00:00 EDT 2022

Transcriptomic analysis of CFTR-impaired endothelial cells reveals a pro-inflammatory phenotype.

The European respiratory journal

Declercq M,de Zeeuw P,Conchinha NV,Geldhof V,Ramalho AS,García-Caballero M,Brepoels K,Ensinck M,Carlon MS,Bird MJ,Vinckier S,Proesmans M,Vermeulen F,Dupont L,Ghesquière B,Dewerchin M,Carmeliet P,Cassiman D,Treps L,Eelen G,Witters P

48-0341-82 was used in Flow Cytometry to suggest that ECs are no innocent bystanders in CF pathology, but rather may contribute to the exaggerated inflammatory phenotype, raising the question whether normalisation of vascular inflammation might be a novel therapeutic strategy to ameliorate the disease severity of CF.

Thu Apr 01 00:00:00 EDT 2021

Glomerular endothelial cell senescence drives age-related kidney disease through PAI-1.

EMBO molecular medicine

Cohen C,Le Goff O,Soysouvanh F,Vasseur F,Tanou M,Nguyen C,Amrouche L,Le Guen J,Saltel-Fulero O,Meunier T,Nguyen-Khoa T,Rabant M,Nochy D,Legendre C,Friedlander G,Childs BG,Baker DJ,Knebelmann B,Anglicheau D,Milliat F,Terzi F

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunocytochemistry

Mon Nov 08 00:00:00 EST 2021

Induction of osteogenic differentiation of bone marrow stromal cells on 3D polyester-based scaffolds solely by subphysiological fluidic stimulation in a laminar flow bioreactor.

Journal of tissue engineering

Yamada S,Yassin MA,Schwarz T,Hansmann J,Mustafa K

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Jul 16 00:00:00 EDT 2021

Functional damage of endothelial progenitor cells is attenuated by 14-3-3-n through inhibition of mitochondrial injury and oxidative stress.

Cell biology international

Li Y,Sun X,Zhang X,Zhou H,Wang D,Xia Y,Li X

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunocytochemistry

Thu Apr 01 00:00:00 EDT 2021

Functional damage of endothelial progenitor cells is attenuated by 14-3-3-n through inhibition of mitochondrial injury and oxidative stress.

Cell biology international

Li Y,Sun X,Zhang X,Zhou H,Wang D,Xia Y,Li X

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunocytochemistry

Thu Apr 01 00:00:00 EDT 2021

Functional Specificity of the Members of the Sos Family of Ras-GEF Activators: Novel Role of Sos2 in Control of Epidermal Stem Cell Homeostasis.

Cancers

Baltanás FC,Mucientes-Valdivieso C,Lorenzo-Martín LF,Fernández-Parejo N,García-Navas R,Segrelles C,Calzada N,Fuentes-Mateos R,Paramio JM,Bustelo XR,Santos E

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Apr 29 00:00:00 EDT 2021

Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regeneration.

PLoS genetics

Flora P,Li MY,Galbo PM,Astorkia M,Zheng D,Ezhkova E

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Wed Dec 01 00:00:00 EST 2021

Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.

International journal of molecular sciences

Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Feb 04 00:00:00 EST 2021

Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat.

Stem cell research & therapy

Tang H,Zhang P,Zeng L,Zhao Y,Xie L,Chen B

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Jul 16 00:00:00 EDT 2021

Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue.

Nature communications

Ribas-Latre A,Santos RB,Fekry B,Tamim YM,Shivshankar S,Mohamed AMT,Baumgartner C,Kwok C,Gebhardt C,Rivera A,Gao Z,Sun K,Heiker JT,Snyder BE,Kolonin MG,Eckel-Mahan KL

48-0341-82 was used in Flow Cytometry to conclude that the circadian clock and feeding simultaneously impart dynamic, regulatory control of adipocyte progenitor proliferation, which may be a critical determinant of adipose tissue expansion and health over time.

Wed Jun 09 00:00:00 EDT 2021

Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells.

JCI insight

Hinterbrandner M,Rubino V,Stoll C,Forster S,Schnüriger N,Radpour R,Baerlocher GM,Ochsenbein AF,Riether C

48-0341-82 was used in Flow Cytometry to identify Tregs as key regulators of immune escape of leukemia stem cells and tumour necrosis factor receptor 4 as a potential target to reduce the function of Tregs and boost antileukemic immunity in chronic myeloid leukemia.

Wed Dec 08 00:00:00 EST 2021

Transmission of trained immunity and heterologous resistance to infections across generations.

Nature immunology

Katzmarski N,Domínguez-Andrés J,Cirovic B,Renieris G,Ciarlo E,Le Roy D,Lepikhov K,Kattler K,Gasparoni G,Händler K,Theis H,Beyer M,van der Meer JWM,Joosten LAB,Walter J,Schultze JL,Roger T,Giamarellos-Bourboulis EJ,Schlitzer A,Netea MG

48-0341-82 was used in Flow Cytometry to provide evidence for inheritance of trained immunity in mammals, enhancing protection against infections.

Mon Nov 01 00:00:00 EDT 2021

Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate.

Frontiers in cell and developmental biology

Tang W,He J,Huang T,Bai Z,Wang C,Wang H,Yang R,Ni Y,Hou J,Wang J,Zhou J,Yao Y,Gong Y,Hou S,Liu B,Lan Y

48-0341-82 was used in Flow cytometry/Cell sorting to develop an Hlf-tdTomato reporter mouse model and detected Hlf-tdTomato expression exclusively in the hematopoietic cells including part of the immunophenotypic CD45- and CD45+ pre-HSCs in the embryonic day (E) 10.5 AGM region.

Fri Oct 01 00:00:00 EDT 2021

Adipose-derived stem cells therapy effectively attenuates PM_2.5-induced lung injury.

Stem cell research & therapy

Gao J,Yuan J,Liu Q,Wang Y,Wang H,Chen Y,Ding W,Ji G,Lu Z

48-0341-82 was used in Flow Cytometry to suggest that ADSC transplantation may be a potential therapeutic approach for severe air pollution-associated diseases.

Sat Jun 19 00:00:00 EDT 2021

Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia.

The Journal of clinical investigation

Oppezzo A,Bourseguin J,Renaud E,Pawlikowska P,Rosselli F

48-0341 was used in Flow cytometry/Cell sorting to the impact of the constitutive activation of stress signaling pathways on hematopoietic stem cell maintenance and function in Fanconi anemia.

Mon Mar 02 00:00:00 EST 2020

Glutamylation of deubiquitinase BAP1 controls self-renewal of hematopoietic stem cells and hematopoiesis.

The Journal of experimental medicine

Xiong Z,Xia P,Zhu X,Geng J,Wang S,Ye B,Qin X,Qu Y,He L,Fan D,Du Y,Tian Y,Fan Z

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Mon Feb 03 00:00:00 EST 2020

SIRT7 activates quiescent hair follicle stem cells to ensure hair growth in mice.

The EMBO journal

Li G,Tang X,Zhang S,Jin M,Wang M,Deng Z,Liu Z,Qian M,Shi W,Wang Z,Xie H,Li J,Liu B

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Tue Sep 15 00:00:00 EDT 2020

A smooth muscle-derived, Braf-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin.

The Journal of pathology

Kondo J,Huh WJ,Franklin JL,Heinrich MC,Rubin BP,Coffey RJ

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunocytochemistry

Tue Dec 01 00:00:00 EST 2020

Sema3A and HIF1α co-overexpressed iPSC-MSCs/HA scaffold facilitates the repair of calvarial defect in a mouse model.

Journal of cellular physiology

Li J,Wang T,Li C,Wang Z,Wang P,Zheng L

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Allogeneic adipose-derived stem cells promote ischemic muscle repair by inducing M2 macrophage polarization via the HIF-1α/IL-10 pathway.

Stem cells (Dayton, Ohio)

Liu J,Qiu P,Qin J,Wu X,Wang X,Yang X,Li B,Zhang W,Ye K,Peng Z,Lu X

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Explant culture: A relevant tool for the study of telocytes.

Cell biology international

Sanches BDA,Maldarine JDS,Tamarindo GH,Da Silva ADT,Lima MLD,Rahal P,Góes RM,Taboga SR,Carvalho HF

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunocytochemistry

Tue Dec 01 00:00:00 EST 2020

Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.

Nature communications

Wilkes MC,Siva K,Chen J,Varetti G,Youn MY,Chae H,Ek F,Olsson R,Lundbäck T,Dever DP,Nishimura T,Narla A,Glader B,Nakauchi H,Porteus MH,Repellin CE,Gazda HT,Lin S,Serrano M,Flygare J,Sakamoto KM

48-0341 was used in Flow cytometry/Cell sorting to report the identification of Nemo-like kinase (NLK) as a potential target for DBA therapy.

Fri Jul 03 00:00:00 EDT 2020

Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.

Nature communications

Wilkes MC,Siva K,Chen J,Varetti G,Youn MY,Chae H,Ek F,Olsson R,Lundbäck T,Dever DP,Nishimura T,Narla A,Glader B,Nakauchi H,Porteus MH,Repellin CE,Gazda HT,Lin S,Serrano M,Flygare J,Sakamoto KM

48-0341 was used in Flow cytometry/Cell sorting to report the identification of Nemo-like kinase (NLK) as a potential target for DBA therapy.

Fri Jul 03 00:00:00 EDT 2020

Histone H3 K4/9/27 Trimethylation Levels Affect Wound Healing and Stem Cell Dynamics in Adult Skin.

Stem cell reports

Kang S,Long K,Wang S,Sada A,Tumbar T

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Tue Jan 14 00:00:00 EST 2020

Small GTPase RAB6 deficiency promotes alveolar progenitor cell renewal and attenuates PM2.5-induced lung injury and fibrosis.

Cell death & disease

Yang L,Liu G,Li X,Xia Z,Wang Y,Lin W,Zhang W,Zhang W,Li X

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Sun Oct 04 00:00:00 EDT 2020

Defining the role of pulmonary endothelial cell heterogeneity in the response to acute lung injury.

eLife

Niethamer TK,Stabler CT,Leach JP,Zepp JA,Morley MP,Babu A,Zhou S,Morrisey EE

48-0341 was used in Flow cytometry/Cell sorting to identify that different subtypes of endothelial cells exist in capillaries, and that some may be able to perform slightly different jobs during lung recovery.

Mon Feb 24 00:00:00 EST 2020

Novel CD11b⁺Gr-1⁺Sca-1⁺ myeloid cells drive mortality in bacterial infection.

Science advances

Park MY,Kim HS,Lee HY,Zabel BA,Bae YS

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.

Nature

Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Mon Jul 01 00:00:00 EDT 2019

The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids.

Cell stem cell

Seneviratne AK,Xu M,Henao JJA,Fajardo VA,Hao Z,Voisin V,Xu GW,Hurren R,Kim S,MacLean N,Wang X,Gronda M,Jeyaraju D,Jitkova Y,Ketela T,Mullokandov M,Sharon D,Thomas G,Chouinard-Watkins R,Hawley JR,Schafer C,Yau HL,Khuchua Z,Aman A,Al-Awar R,Gross A,Claypool SM,Bazinet RP,Lupien M,Chan S,De Carvalho DD,Minden MD,Bader GD,Stark KD,LeBlanc P,Schimmer AD

48-0341 was used in Flow cytometry/Cell sorting to show that mechanistically, inhibition of TAZ decreased levels of cardiolipin but also altered global levels of intracellular phospholipids, including phosphatidylserine, which controlled AML stemness and differentiation by modulating toll-like receptor (TLR) signaling.

Thu Apr 04 00:00:00 EDT 2019

Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer.

The Journal of clinical investigation

Soukup AA,Zheng Y,Mehta C,Wu J,Liu P,Cao M,Hofmann I,Zhou Y,Zhang J,Johnson KD,Choi K,Keles S,Bresnick EH

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Mar 01 00:00:00 EST 2019

Mesenchymal VEGFA induces aberrant differentiation in heterotopic ossification.

Bone research

Hwang C,Marini S,Huber AK,Stepien DM,Sorkin M,Loder S,Pagani CA,Li J,Visser ND,Vasquez K,Garada MA,Li S,Xu J,Hsu CY,Yu PB,James AW,Mishina Y,Agarwal S,Li J,Levi B

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Sun Oct 17 00:00:00 EDT 2021

Transcriptional Analysis of Sepsis-Induced Activation and Damage of the Adrenal Endothelial Microvascular Cells.

Frontiers in endocrinology

Chen LS,Singh SP,Müller G,Bornstein SR,Kanczkowski W

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunocytochemistry

Fri Feb 14 00:00:00 EST 2020

Transcriptional Analysis of Sepsis-Induced Activation and Damage of the Adrenal Endothelial Microvascular Cells.

Frontiers in endocrinology

Chen LS,Singh SP,Müller G,Bornstein SR,Kanczkowski W

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunocytochemistry

Fri Feb 14 00:00:00 EST 2020

Protumoral bone marrow-derived cells migrate via Gβγ-dependent signaling pathways and exhibit a complex repertoire of RhoGEFs.

Journal of cell communication and signaling

Cervantes-Villagrana RD,Color-Aparicio VM,Reyes-Cruz G,Vázquez-Prado J

48-0341 was used in Flow cytometry/Cell sorting to show that a protumoral population of cultured bone marrow-derived cells containing Tie2+/CD45+/CD11b + cells responded to lung carcinoma cells and reciprocally stimulated them.

Sat Jun 01 00:00:00 EDT 2019

Pharmacological exposures may precipitate craniosynostosis through targeted stem cell depletion.

Stem cell research

Durham E,Howie RN,Larson N,LaRue A,Cray J

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

Pharmacological exposures may precipitate craniosynostosis through targeted stem cell depletion.

Stem cell research

Durham E,Howie RN,Larson N,LaRue A,Cray J

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.

International journal of molecular sciences

Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Tue Mar 05 00:00:00 EST 2019

Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.

International journal of molecular sciences

Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Tue Mar 05 00:00:00 EST 2019

Dietary calories and lipids synergistically shape adipose tissue cellularity during postnatal growth.

Molecular metabolism

Meln I,Wolff G,Gajek T,Koddebusch J,Lerch S,Harbrecht L,Hong W,Bayindir-Buchhalter I,Krunic D,Augustin HG,Vegiopoulos A

48-0341 was used in Flow cytometry/Cell sorting to show that dietary lipids and calories differentially and synergistically drive adipose tissue proliferative growth and the programming of the metabolic syndrome in childhood.

Sat Jun 01 00:00:00 EDT 2019

Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production.

Frontiers in immunology

Kiss MG,Ozsvár-Kozma M,Porsch F,Göderle L,Papac-Miličević N,Bartolini-Gritti B,Tsiantoulas D,Pickering MC,Binder CJ

48-0341-82 was used in Flow Cytometry to indicate that CFH, through its function as a complement repressor, acts as a negative regulator of BCR signaling and limits autoimmunity.

Tue Oct 13 00:00:00 EDT 2020

Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation.

The Journal of experimental medicine

Nagase R,Inoue D,Pastore A,Fujino T,Hou HA,Yamasaki N,Goyama S,Saika M,Kanai A,Sera Y,Horikawa S,Ota Y,Asada S,Hayashi Y,Kawabata KC,Takeda R,Tien HF,Honda H,Abdel-Wahab O,Kitamura T

48-0341 was used in Flow cytometry/Cell sorting to study the effects of physiological expression of a C-terminal truncated AsXenopus laevis1 mutant in vivo.

Mon Jun 04 00:00:00 EDT 2018

p110α of PI3K is necessary and sufficient for quiescence exit in adult muscle satellite cells.

The EMBO journal

Wang G,Zhu H,Situ C,Han L,Yu Y,Cheung TH,Liu K,Wu Z

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunocytochemistry

Fri Apr 13 00:00:00 EDT 2018

Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis.

Journal of cell science

Pala F,Di Girolamo D,Mella S,Yennek S,Chatre L,Ricchetti M,Tajbakhsh S

48-0341 was used in Flow cytometry/Cell sorting to characterise the metabolic pathways that mediate the commitment and differentiation of mouse skeletal muscle stem cells, and how their modulation can influence the cell state.

Fri Jul 27 00:00:00 EDT 2018

Utilizing Confocal Microscopy to Characterize Human and Mouse Adipose Tissue.

Tissue engineering. Part C, Methods

Blackshear CP,Borrelli MR,Shen EZ,Ransom RC,Chung NN,Vistnes SM,Irizarry D,Nazerali R,Momeni A,Longaker MT,Wan DC

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunocytochemistry

Mon Oct 01 00:00:00 EDT 2018

Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43.

Experimental and therapeutic medicine

Li Z,Zhang S,Cao L,Li W,Ye YC,Shi ZX,Wang ZR,Sun LX,Wang JW,Jia LT,Wang W

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells.

Nature communications

Nguyen MB,Cohen I,Kumar V,Xu Z,Bar C,Dauber-Decker KL,Tsai PC,Marangoni P,Klein OD,Hsu YC,Chen T,Mikkola ML,Ezhkova E

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunofluorescence

Wed Jun 13 00:00:00 EDT 2018

JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin.

Nature communications

Singh K,Camera E,Krug L,Basu A,Pandey RK,Munir S,Wlaschek M,Kochanek S,Schorpp-Kistner M,Picardo M,Angel P,Niemann C,Maity P,Scharffetter-Kochanek K

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Aug 24 00:00:00 EDT 2018

JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin.

Nature communications

Singh K,Camera E,Krug L,Basu A,Pandey RK,Munir S,Wlaschek M,Kochanek S,Schorpp-Kistner M,Picardo M,Angel P,Niemann C,Maity P,Scharffetter-Kochanek K

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Aug 24 00:00:00 EDT 2018

Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice.

The Journal of biological chemistry

Zhao J,Tian Z,Kadomatsu T,Xie P,Miyata K,Sugizaki T,Endo M,Zhu S,Fan H,Horiguchi H,Morinaga J,Terada K,Yoshizawa T,Yamagata K,Oike Y

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Fri Feb 02 00:00:00 EST 2018

Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice.

The Journal of biological chemistry

Zhao J,Tian Z,Kadomatsu T,Xie P,Miyata K,Sugizaki T,Endo M,Zhu S,Fan H,Horiguchi H,Morinaga J,Terada K,Yoshizawa T,Yamagata K,Oike Y

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Fri Feb 02 00:00:00 EST 2018

RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism.

Small GTPases

García-Mariscal A,Peyrollier K,Basse A,Pedersen E,Rühl R,van Hengel J,Brakebusch C

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Mon Sep 03 00:00:00 EDT 2018

Proteinase 3 Limits the Number of Hematopoietic Stem and Progenitor Cells in Murine Bone Marrow.

Stem cell reports

Karatepe K,Zhu H,Zhang X,Guo R,Kambara H,Loison F,Liu P,Yu H,Ren Q,Luo X,Manis J,Cheng T,Ma F,Xu Y,Luo HR

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Tue Nov 13 00:00:00 EST 2018

Small-RNA sequencing identifies dynamic microRNA deregulation during skeletal muscle lineage progression.

Scientific reports

Castel D,Baghdadi MB,Mella S,Gayraud-Morel B,Marty V,Cavaillé J,Antoniewski C,Tajbakhsh S

48-0341 was used in Flow cytometry/Cell sorting to uncover a key resource for functional analyses of miRNAs in skeletal myogenesis and in the regulation of stem cell self-renewal and tissue homeostasis.

Fri Mar 09 00:00:00 EST 2018

Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress.

Cell stem cell

Tadokoro Y,Hoshii T,Yamazaki S,Eto K,Ema H,Kobayashi M,Ueno M,Ohta K,Arai Y,Hara E,Harada K,Oshima M,Oshima H,Arai F,Yoshimura A,Nakauchi H,Hirao A

48-0341-82 was used in Flow Cytometry to demonstrate the involvement of diet-induced stress on hematopoietic stem cell self-renewal.

Thu May 03 00:00:00 EDT 2018

Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells.

Nature communications

Tosic M,Allen A,Willmann D,Lepper C,Kim J,Duteil D,Schüle R

48-0341 was used in Flow cytometry/Cell sorting to show that elevated levels of lysine-specific demethylase 1 have a beneficial effect on muscle regeneration and recovery after injury.

Thu Jan 25 00:00:00 EST 2018

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium.

eLife

Schlereth K,Weichenhan D,Bauer T,Heumann T,Giannakouri E,Lipka D,Jaeger S,Schlesner M,Aloy P,Eils R,Plass C,Augustin HG

48-0341 was used in Flow cytometry/Cell sorting to establish the transcriptional and epigenetic landscape of vascular quiescence in the continuous lung endothelium.

Fri May 11 00:00:00 EDT 2018

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.

Nature medicine

Fenouille N,Bassil CF,Ben-Sahra I,Benajiba L,Alexe G,Ramos A,Pikman Y,Conway AS,Burgess MR,Li Q,Luciano F,Auberger P,Galinsky I,DeAngelo DJ,Stone RM,Zhang Y,Perkins AS,Shannon K,Hemann MT,Puissant A,Stegmaier K

48-0341 was used in Flow cytometry/Cell sorting to investigate the effect of MECOM on cellular metabolism.

Wed Mar 01 00:00:00 EST 2017

Inflammatory memory sensitizes skin epithelial stem cells to tissue damage.

Nature

Naik S,Larsen SB,Gomez NC,Alaverdyan K,Sendoel A,Yuan S,Polak L,Kulukian A,Chai S,Fuchs E

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Oct 26 00:00:00 EDT 2017

Lactate dehydrogenase activity drives hair follicle stem cell activation.

Nature cell biology

Flores A,Schell J,Krall AS,Jelinek D,Miranda M,Grigorian M,Braas D,White AC,Zhou JL,Graham NA,Graeber T,Seth P,Evseenko D,Coller HA,Rutter J,Christofk HR,Lowry WE

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Sep 01 00:00:00 EDT 2017

A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice.

Haematologica

Cañete A,Carmona R,Ariza L,Sánchez MJ,Rojas A,Muñoz-Chápuli R

48034182 was used in flow cytometry to utilize a G2-Gata4Cre;R26REYFP mouse line to track the developmental fate of the G2-Gata4 cell lineage

Sat Apr 01 00:00:00 EDT 2017

LCN2 overexpression in bone enhances the hematopoietic compartment via modulation of the bone marrow microenvironment.

Journal of cellular physiology

Costa D,Principi E,Lazzarini E,Descalzi F,Cancedda R,Castagnola P,Tavella S

48034182 was used in flow cytometry to examine the function of lipocalin-2 in bone tissue

Wed Nov 01 00:00:00 EDT 2017

Tissue-engineered sling with adipose-derived stem cells under static mechanical strain.

Experimental and therapeutic medicine

Wang Y,Wang W,Wang X,Wang Y,Wang J,Fu Q,Shi G

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2017

Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.

PloS one

Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Mon Sep 18 00:00:00 EDT 2017

14-3-3ζ loss leads to neonatal lethality by microRNA-126 downregulation-mediated developmental defects in lung vasculature.

Cell & bioscience

Yang J,Joshi S,Wang Q,Li P,Wang H,Xiong Y,Xiao Y,Wang J,Parker-Thornburg J,Behringer RR,Yu D

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Thu Mar 10 00:00:00 EST 2022

Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle.

Cell stem cell

Chiche A,Le Roux I,von Joest M,Sakai H,Aguín SB,Cazin C,Salam R,Fiette L,Alegria O,Flamant P,Tajbakhsh S,Li H

48-0341 was used in Flow cytometry/Cell sorting to study the effects of acute and chronic injury on transcription-factor-mediated reprogramming in skeletal muscle.

Thu Mar 02 00:00:00 EST 2017

Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation.

The Journal of investigative dermatology

Devos M,Gilbert B,Denecker G,Leurs K,Mc Guire C,Lemeire K,Hochepied T,Vuylsteke M,Lambert J,Van Den Broecke C,Libbrecht L,Haigh J,Berx G,Lippens S,Vandenabeele P,Declercq W

48-0341-82 was used in Flow cytometry/Cell sorting to show that increased ΔNp63α protein levels facilitate oncogenic transformation in the epidermis as well as in the bile duct.

Wed Feb 01 00:00:00 EST 2017

lncRNA requirements for mouse acute myeloid leukemia and normal differentiation.

eLife

Delás MJ,Sabin LR,Dolzhenko E,Knott SR,Munera Maravilla E,Jackson BT,Wild SA,Kovacevic T,Stork EM,Zhou M,Erard N,Lee E,Kelley DR,Roth M,Barbosa IA,Zuber J,Rinn JL,Smith AD,Hannon GJ

48-0341 was used in Flow cytometry/Cell sorting to assess lncRNA function via an in vivo RNAi screen in a model of acute myeloid leukemia.

Wed Sep 06 00:00:00 EDT 2017

Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation.

PloS one

Zhao Y,Wu K,Nguyen C,Smbatyan G,Melendez E,Higuchi Y,Chen Y,Kahn M

48-0341 was used in Flow cytometry/Cell sorting to report that the small molecule YH250 stimulates hematopoiesis in lethally or sublethally irradiated mice.

Tue Sep 26 00:00:00 EDT 2017

Stem cell function and stress response are controlled by protein synthesis.

Nature

Blanco S,Bandiera R,Popis M,Hussain S,Lombard P,Aleksic J,Sajini A,Tanna H,Cortés-Garrido R,Gkatza N,Dietmann S,Frye M

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Jun 16 00:00:00 EDT 2016

Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis.

The Journal of clinical investigation

Gu H,Chen C,Hao X,Wang C,Zhang X,Li Z,Shao H,Zeng H,Yu Z,Xie L,Xia F,Zhang F,Liu X,Zhang Y,Jiang H,Zhu J,Wan J,Wang C,Weng W,Xie J,Tao M,Zhang CC,Liu J,Chen GQ,Zheng J

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2016

Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification.

Annals of surgery

Loder S,Agarwal S,Sorkin M,Breuler C,Li J,Peterson J,Gardenier J,Hsieh HH,Wang SC,Mehrara BJ,Levi B

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Dec 01 00:00:00 EST 2016

Serially Transplanted Nonpericytic CD146(-) Adipose Stromal/Stem Cells in Silk Bioscaffolds Regenerate Adipose Tissue In Vivo.

Stem cells (Dayton, Ohio)

Frazier TP,Bowles A,Lee S,Abbott R,Tucker HA,Kaplan D,Wang M,Strong A,Brown Q,He J,Bunnell BA,Gimble JM

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.

Stem cells (Dayton, Ohio)

Agarwal S,Loder SJ,Sorkin M,Li S,Shrestha S,Zhao B,Mishina Y,James AW,Levi B

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Wed Jun 01 00:00:00 EDT 2016

Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification.

Stem cells (Dayton, Ohio)

Agarwal S,Loder SJ,Sorkin M,Li S,Shrestha S,Zhao B,Mishina Y,James AW,Levi B

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Wed Jun 01 00:00:00 EDT 2016

Macrophages form functional vascular mimicry channels in vivo.

Scientific reports

Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M

48-0341 was used in Flow cytometry/Cell sorting to demonstrate that macrophages are capable of forming primitive, non-endothelial vessels in models of tumours and angiogenesis.

Fri Nov 11 00:00:00 EST 2016

Lgr5+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors.

Oncotarget

van de Glind GC,Out-Luiting JJ,Rebel HG,Tensen CP,de Gruijl FR

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunofluorescence

Tue Aug 09 00:00:00 EDT 2016

PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells.

Nature medicine

Gur-Cohen S,Itkin T,Chakrabarty S,Graf C,Kollet O,Ludin A,Golan K,Kalinkovich A,Ledergor G,Wong E,Niemeyer E,Porat Z,Erez A,Sagi I,Esmon CT,Ruf W,Lapidot T

48-0341 was used in Flow cytometry/Cell sorting to study long-term repopulating hematopoietic stem cells, showing that PAR1 signaling regulates the retention and recruitment of EPCR-expressing hematopoietic stem cells.

Sun Nov 01 00:00:00 EDT 2015

Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool.

Nature

Mesa KR,Rompolas P,Zito G,Myung P,Sun TY,Brown S,Gonzalez DG,Blagoev KB,Haberman AM,Greco V

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Jun 04 00:00:00 EDT 2015

Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver.

Nature

Wang B,Zhao L,Fish M,Logan CY,Nusse R

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Aug 13 00:00:00 EDT 2015

Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis.

Nature cell biology

Iglesias-Bartolome R,Torres D,Marone R,Feng X,Martin D,Simaan M,Chen M,Weinstein LS,Taylor SS,Molinolo AA,Gutkind JS

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunofluorescence

Mon Jun 01 00:00:00 EDT 2015

Life-Long Transgene Expression in Skeletal Muscle Without Transduction of Satellite Cells Following Embryonic Myogenic Progenitor Transduction by Lentivirus Administered in Utero.

Stem cells and development

Stitelman DH,Brazelton TR,Endo M,Bora A,Traas J,Zoltick PW,Flake AW

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Sat Aug 15 00:00:00 EDT 2015

Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle.

eLife

Xu Z,Wang W,Jiang K,Yu Z,Huang H,Wang F,Zhou B,Chen T

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunofluorescence

Mon Dec 14 00:00:00 EST 2015

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles.

Nature medicine

Cosgrove BD,Gilbert PM,Porpiglia E,Mourkioti F,Lee SP,Corbel SY,Llewellyn ME,Delp SL,Blau HM

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Sat Mar 01 00:00:00 EST 2014

c-kit+ cells minimally contribute cardiomyocytes to the heart.

Nature

van Berlo JH,Kanisicak O,Maillet M,Vagnozzi RJ,Karch J,Lin SC,Middleton RC,Marbán E,Molkentin JD

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunofluorescence

Thu May 15 00:00:00 EDT 2014

Mesenchymal-endothelial transition contributes to cardiac neovascularization.

Nature

Ubil E,Duan J,Pillai IC,Rosa-Garrido M,Wu Y,Bargiacchi F,Lu Y,Stanbouly S,Huang J,Rojas M,Vondriska TM,Stefani E,Deb A

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Oct 30 00:00:00 EDT 2014

Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium.

The Journal of clinical investigation

Moding EJ,Lee CL,Castle KD,Oh P,Mao L,Zha S,Min HD,Ma Y,Das S,Kirsch DG

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Aug 01 00:00:00 EDT 2014

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.

The Journal of experimental medicine

Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Mon Sep 22 00:00:00 EDT 2014

Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling.

Journal of immunology (Baltimore, Md. : 1950)

Balmer ML,Schürch CM,Saito Y,Geuking MB,Li H,Cuenca M,Kovtonyuk LV,McCoy KD,Hapfelmeier S,Ochsenbein AF,Manz MG,Slack E,Macpherson AJ

48-0341 was used in Flow cytometry/Cell sorting to investigate the cross talk between haematopoiesis and intestinal microbiota.

Sat Nov 15 00:00:00 EST 2014

Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation.

Molecular and cellular biology

Siu KT,Xu Y,Swartz KL,Bhattacharyya M,Gurbuxani S,Hua Y,Minella AC

48-0341 was used in Flow cytometry/Cell sorting to investigate the contribution of individual substrate ubiquitination pathways to hematopoietic stem cell homeostasis, showing that impaired Fbw7-mediated cyclin E regulation leads to chromosome instability.

Mon Sep 01 00:00:00 EDT 2014

Hypoxia-cultured human adipose-derived mesenchymal stem cells are non-oncogenic and have enhanced viability, motility, and tropism to brain cancer.

Cell death & disease

Feng Y,Zhu M,Dangelmajer S,Lee YM,Wijesekera O,Castellanos CX,Denduluri A,Chaichana KL,Li Q,Zhang H,Levchenko A,Guerrero-Cazares H,Quiñones-Hinojosa A

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Dec 11 00:00:00 EST 2014

Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network.

Cell reports

Fang J,Barker B,Bolanos L,Liu X,Jerez A,Makishima H,Christie S,Chen X,Rao DS,Grimes HL,Komurov K,Weirauch MT,Cancelas JA,Maciejewski JP,Starczynowski DT

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Thu Sep 11 00:00:00 EDT 2014

Developmental stage determines efficiency of gene transfer to muscle satellite cells by in utero delivery of adeno-associated virus vector serotype 2/9.

Molecular therapy. Methods & clinical development

Stitelman DH,Brazelton T,Bora A,Traas J,Merianos D,Limberis M,Davey M,Flake AW

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Wed May 27 00:00:00 EDT 2015

State-dependent signaling by Cav1.2 regulates hair follicle stem cell function.

Genes & development

Yucel G,Altindag B,Gomez-Ospina N,Rana A,Panagiotakos G,Lara MF,Dolmetsch R,Oro AE

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunofluorescence

Sat Jun 01 00:00:00 EDT 2013

Sonic hedgehog signals to multiple prostate stromal stem cells that replenish distinct stromal subtypes during regeneration.

Proceedings of the National Academy of Sciences of the United States of America

Peng YC,Levine CM,Zahid S,Wilson EL,Joyner AL

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunofluorescence

Tue Dec 17 00:00:00 EST 2013

Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing Cre recombinase exclusively in eosinophils.

Journal of leukocyte biology

Doyle AD,Jacobsen EA,Ochkur SI,Willetts L,Shim K,Neely J,Kloeber J,Lesuer WE,Pero RS,Lacy P,Moqbel R,Lee NA,Lee JJ

48-0341 was used in Flow cytometry/Cell sorting to develop a novel murine strain to allow a better definition of the role of eosinophils in health and disease.

Mon Jul 01 00:00:00 EDT 2013

A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).

Disease models & mechanisms

Carofino BL,Ayanga B,Justice MJ

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Nov 01 00:00:00 EDT 2013

Microfluidic enrichment of mouse epidermal stem cells and validation of stem cell proliferation in vitro.

Tissue engineering. Part C, Methods

Zhu B,Smith J,Yarmush ML,Nahmias Y,Kirby BJ,Murthy SK

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2013

Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans.

PloS one

Park SO,Wamsley HL,Bae K,Hu Z,Li X,Choe SW,Slayton WB,Oh SP,Wagner KU,Sayeski PP

48-0341 was used in Flow cytometry/Cell sorting to understand the role played by Jak2 at varying stages of prenatal and postnatal life.

Tue Sep 17 00:00:00 EDT 2013

Targeted disruption of heparan sulfate interaction with hepatocyte and vascular endothelial growth factors blocks normal and oncogenic signaling.

Cancer cell

Cecchi F,Pajalunga D,Fowler CA,Uren A,Rabe DC,Peruzzi B,Macdonald NJ,Blackman DK,Stahl SJ,Byrd RA,Bottaro DP

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Tue Aug 14 00:00:00 EDT 2012

Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization.

Cell

Ding BS,Nolan DJ,Guo P,Babazadeh AO,Cao Z,Rosenwaks Z,Crystal RG,Simons M,Sato TN,Worgall S,Shido K,Rabbany SY,Rafii S

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Flow Cytometry

Fri Oct 28 00:00:00 EDT 2011

CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration.

Stem cells (Dayton, Ohio)

Alfaro LA,Dick SA,Siegel AL,Anonuevo AS,McNagny KM,Megeney LA,Cornelison DD,Rossi FM

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Thu Dec 01 00:00:00 EST 2011

CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration.

Stem cells (Dayton, Ohio)

Alfaro LA,Dick SA,Siegel AL,Anonuevo AS,McNagny KM,Megeney LA,Cornelison DD,Rossi FM

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Thu Dec 01 00:00:00 EST 2011

CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration.

Stem cells (Dayton, Ohio)

Alfaro LA,Dick SA,Siegel AL,Anonuevo AS,McNagny KM,Megeney LA,Cornelison DD,Rossi FM

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Thu Dec 01 00:00:00 EST 2011

Improved intratumoral oxygenation through vascular normalization increases glioma sensitivity to ionizing radiation.

International journal of radiation oncology, biology, physics

McGee MC,Hamner JB,Williams RF,Rosati SF,Sims TL,Ng CY,Gaber MW,Calabrese C,Wu J,Nathwani AC,Duntsch C,Merchant TE,Davidoff AM

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunohistochemistry

Thu Apr 01 00:00:00 EDT 2010

Progenitors of skeletal muscle satellite cells express the muscle determination gene, MyoD.

Developmental biology

Kanisicak O,Mendez JJ,Yamamoto S,Yamamoto M,Goldhamer DJ

Published figure using CD34 monoclonal antibody (Product # 48-0341-82) in Immunofluorescence

Sat Aug 01 00:00:00 EDT 2009

Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow.

Stem cells (Dayton, Ohio)

Singh P,Yao Y,Weliver A,Broxmeyer HE,Hong SC,Chang CH

Tue Apr 01 00:00:00 EDT 2008

The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.

The Journal of biological chemistry

Palazuelos J,Davoust N,Julien B,Hatterer E,Aguado T,Mechoulam R,Benito C,Romero J,Silva A,Guzmán M,Nataf S,Galve-Roperh I

Fri May 09 00:00:00 EDT 2008

Integrin-linked kinase is required for epidermal and hair follicle morphogenesis.

The Journal of cell biology

Lorenz K,Grashoff C,Torka R,Sakai T,Langbein L,Bloch W,Aumailley M,Fässler R

Mon May 07 00:00:00 EDT 2007

Hair cycle-dependent changes of alkaline phosphatase activity in the mesenchyme and epithelium in mouse vibrissal follicles.

Development, growth & differentiation

Iida M,Ihara S,Matsuzaki T

Sun Apr 01 00:00:00 EDT 2007

Bioinformatics

Protein Aliases: CD34; cluster designation 34; Hematopoietic progenitor cell antigen CD34; Mucosialin; RP11-328D5.2

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Gene Aliases: AU040960; Cd34

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UniProt ID: (Mouse) Q64314

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Entrez Gene ID: (Mouse) 12490

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Function(s)

transcription factor binding carbohydrate binding sulfate binding cell adhesion molecule

Process(es)

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CD34 Monoclonal Antibody (RAM34), eFluor™ 450, eBioscience™

CD34 Antibody (48-0341-82) in Flow

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48-0341-82

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