Product References
Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells.
Cancer immunology, immunotherapy : CII
Symonds ALJ,Miao T,Busharat Z,Li S,Wang P
48-9985-82 was used in Flow cytometry/Cell sorting to conclude that Egr2 and 3 are important for maintaining anti-tumour responses of exhausted CD8 + TILs.
Mon May 01 00:00:00 EDT 2023
CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury.
The Journal of clinical investigation
Sato Y,Oguchi A,Fukushima Y,Masuda K,Toriu N,Taniguchi K,Yoshikawa T,Cui X,Kondo M,Hosoi T,Komidori S,Shimizu Y,Fujita H,Jiang L,Kong Y,Yamanashi T,Seita J,Yamamoto T,Toyokuni S,Hamazaki Y,Hattori M,Yoshikai Y,Boor P,Floege J,Kawamoto H,Murakawa Y,Minato N,Yanagita M
48-9985-82 was used in Flow Cytometry to reveal a previously unappreciated function of CD153/CD30 signaling in TLT formation and propose targeting the CD153/CD30 signaling pathway as a therapeutic target for slowing kidney disease progression.
Tue Jan 18 00:00:00 EST 2022
CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury.
The Journal of clinical investigation
Sato Y,Oguchi A,Fukushima Y,Masuda K,Toriu N,Taniguchi K,Yoshikawa T,Cui X,Kondo M,Hosoi T,Komidori S,Shimizu Y,Fujita H,Jiang L,Kong Y,Yamanashi T,Seita J,Yamamoto T,Toyokuni S,Hamazaki Y,Hattori M,Yoshikai Y,Boor P,Floege J,Kawamoto H,Murakawa Y,Minato N,Yanagita M
48-9985-82 was used in Flow Cytometry to reveal a previously unappreciated function of CD153/CD30 signaling in TLT formation and propose targeting the CD153/CD30 signaling pathway as a therapeutic target for slowing kidney disease progression.
Tue Jan 18 00:00:00 EST 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Ultrasound combined with nanobubbles promotes systemic anticancer immunity and augments anti-PD1 efficacy.
Journal for immunotherapy of cancer
Hu J,He J,Wang Y,Zhao Y,Fang K,Dong Y,Chen Y,Zhang Y,Zhang C,Wang H,Tan J,Wang J,Zi R,Liu C,Liang H,Guo Y,Ou J
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2022
PRDM1/BLIMP1 induces cancer immune evasion by modulating the USP22-SPI1-PD-L1 axis in hepatocellular carcinoma cells.
Nature communications
Li Q,Zhang L,You W,Xu J,Dai J,Hua D,Zhang R,Yao F,Zhou S,Huang W,Dai Y,Zhang Y,Baheti T,Qian X,Pu L,Xu J,Xia Y,Zhang C,Tang J,Wang X
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Mon Dec 12 00:00:00 EST 2022
Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy.
Cell reports
Wang W,Wu S,Cen Z,Zhang Y,Chen Y,Huang Y,Cillo AR,Prokopec JS,Quarato G,Vignali DAA,Stewart-Ornstein J,Li S,Lu B,Gong YN
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
Nature immunology
Gu M,Zhou X,Sohn JH,Zhu L,Jie Z,Yang JY,Zheng X,Xie X,Yang J,Shi Y,Brightbill HD,Kim JB,Wang J,Cheng X,Sun SC
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation.
eLife
Wilfahrt D,Philips RL,Lama J,Kizerwetter M,Shapiro MJ,McCue SA,Kennedy MM,Rajcula MJ,Zeng H,Shapiro VS
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Thu Dec 02 00:00:00 EST 2021
Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.
JCI insight
Ferrere G,Tidjani Alou M,Liu P,Goubet AG,Fidelle M,Kepp O,Durand S,Iebba V,Fluckiger A,Daillère R,Thelemaque C,Grajeda-Iglesias C,Alves Costa Silva C,Aprahamian F,Lefevre D,Zhao L,Ryffel B,Colomba E,Arnedos M,Drubay D,Rauber C,Raoult D,Asnicar F,Spector T,Segata N,Derosa L,Kroemer G,Zitvogel L
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Mon Jan 25 00:00:00 EST 2021
PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer.
Nature communications
Sun Y,Lu D,Yin Y,Song J,Liu Y,Hao W,Qi F,Zhang G,Zhang X,Liu L,Lin Z,Liang H,Zhao X,Jin Y,Yin Y
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Thu Aug 26 00:00:00 EDT 2021
Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity.
Cell reports
Zhou X,Zhu X,Li C,Li Y,Ye Z,Shapiro VS,Copland JA,Hitosugi T,Bernlohr DA,Sun J,Zeng H
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Jan 05 00:00:00 EST 2021
Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.
Frontiers in immunology
Kalim KW,Yang JQ,Modur V,Nguyen P,Li Y,Zheng Y,Guo F
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Jan 11 00:00:00 EST 2022
Knockout of immunotherapy prognostic marker genes eliminates the effect of the anti-PD-1 treatment.
NPJ precision oncology
Yang N,Ji F,Cheng L,Lu J,Sun X,Lin X,Lan X
48-9985 was used in Flow cytometry/Cell sorting to show that knockout of MALT1 can eliminate the antitumor effect of anti-PD-1 treatment completely by impairing the activation of CD8+ T cells.
Fri May 07 00:00:00 EDT 2021
Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses.
Wellcome open research
Wu G,Murugesan G,Nagala M,McCraw A,Haslam SM,Dell A,Crocker PR
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2022
Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection.
The Journal of experimental medicine
Fumagalli V,Di Lucia P,Venzin V,Bono EB,Jordan R,Frey CR,Delaney W,Chisari FV,Guidotti LG,Iannacone M
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Mon Nov 02 00:00:00 EST 2020
B cells are sufficient to prime the dominant CD4+ Tfh response to Plasmodium infection.
The Journal of experimental medicine
Arroyo EN,Pepper M
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Mon Feb 03 00:00:00 EST 2020
Excessive Costimulation Leads to Dysfunction of Adoptively Transferred T Cells.
Cancer immunology research
Wijewarnasuriya D,Bebernitz C,Lopez AV,Rafiq S,Brentjens RJ
48-9985 was used in Flow cytometry/Cell sorting to show excessive CD28 and 4-1BB co-stimulation can drive chimeric antigen receptor T-cell dysfunction.
Mon Jun 01 00:00:00 EDT 2020
Inhibition of the Wnt/β-catenin pathway enhances antitumor immunity in ovarian cancer.
Therapeutic advances in medical oncology
Doo DW,Meza-Perez S,Londoño AI,Goldsberry WN,Katre AA,Boone JD,Moore DJ,Hudson CT,Betella I,McCaw TR,Gangrade A,Bao R,Luke JJ,Yang ES,Birrer MJ,Starenki D,Cooper SJ,Buchsbaum DJ,Norian LA,Randall TD,Arend RC
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2022
Gene silencing of indoleamine 2,3-dioxygenase 1 inhibits lung cancer growth by suppressing T-cell exhaustion.
Oncology letters
Shang K,Wang Z,Hu Y,Huang Y,Yuan K,Yu Y
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease.
Cell reports
Nguyen HD,Ticer T,Bastian D,Kuril S,Li H,Du H,Yan C,Yu XZ
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Oct 27 00:00:00 EDT 2020
5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma.
Frontiers in immunology
Ebelt ND,Zuniga E,Johnson BL,Diamond DJ,Manuel ER
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma.
Frontiers in immunology
Ebelt ND,Zuniga E,Johnson BL,Diamond DJ,Manuel ER
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
The Selenoprotein MsrB1 Instructs Dendritic Cells to Induce T-Helper 1 Immune Responses.
Antioxidants (Basel, Switzerland)
Lee HJ,Park JS,Yoo HJ,Lee HM,Lee BC,Kim JH
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Oct 20 00:00:00 EDT 2020
Endogenous retroviral proteins provide an immunodominant but not requisite antigen in a murine immunotherapy tumor model.
Oncoimmunology
Ye X,Waite JC,Dhanik A,Gupta N,Zhong M,Adler C,Malahias E,Ni M,Wei Y,Gurer C,Zhang W,Macdonald LE,Murphy AJ,Sleeman MA,Skokos D
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Wed May 13 00:00:00 EDT 2020
The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival.
PLoS pathogens
Tuladhar S,Kochanowsky JA,Bhaskara A,Ghotmi Y,Chandrasekaran S,Koshy AA
48-9985-82 was used in Flow Cytometry to show ROP16III in type III strain Toxoplasma gondii can influence the subacute CNS immune response and mediate parasitic survival and persistence.
Tue Oct 01 00:00:00 EDT 2019
Combination PD-1 and PD-L1 Blockade Promotes Durable Neoantigen-Specific T Cell-Mediated Immunity in Pancreatic Ductal Adenocarcinoma.
Cell reports
Burrack AL,Spartz EJ,Raynor JF,Wang I,Olson M,Stromnes IM
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Aug 20 00:00:00 EDT 2019
Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
Cell
Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Thu Jan 25 00:00:00 EST 2018
Role of TFH Cells in Promoting T Helper 17-Induced Neuroinflammation.
Frontiers in immunology
Quinn JL,Kumar G,Agasing A,Ko RM,Axtell RC
48-9985 was used in Flow cytometry/Cell sorting to study how T and B cells cooperate in the pathogenesis of multiple sclerosis.
Mon Apr 08 00:00:00 EDT 2019
PD-1 Blockade Overcomes Adaptive Immune Resistance in Treatment with Anchored-GM-CSF Bladder Cancer Cells Vaccine.
Journal of Cancer
Zhang X,Shi X,Li J,Mo L,Hu Z,Gao J,Wu S,Long Z
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Immunohistochemistry
Thu Oct 01 00:00:00 EDT 2020
PD-1 Blockade Overcomes Adaptive Immune Resistance in Treatment with Anchored-GM-CSF Bladder Cancer Cells Vaccine.
Journal of Cancer
Zhang X,Shi X,Li J,Mo L,Hu Z,Gao J,Wu S,Long Z
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Immunohistochemistry
Thu Oct 01 00:00:00 EDT 2020
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Cancer research
Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Sat Jul 15 00:00:00 EDT 2017
Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.
Oncotarget
Peer S,Baier G,Gruber T
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Jun 27 00:00:00 EDT 2017
Therapeutic efficacy of combined vaccination against tumor pericyte-associated antigens DLK1 and DLK2 in mice.
Oncoimmunology
Fabian KP,Chi-Sabins N,Taylor JL,Fecek R,Weinstein A,Storkus WJ
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression.
Oncoimmunology
Chen L,Yi X,Goswami S,Ahn YH,Roybal JD,Yang Y,Diao L,Peng D,Peng D,Fradette JJ,Wang J,Byers LA,Kurie JM,Ullrich SE,Qin FX,Gibbons DL
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.
Oncoimmunology
Sonner JK,Deumelandt K,Ott M,Thomé CM,Rauschenbach KJ,Schulz S,Munteanu B,Mohapatra S,Adam I,Hofer AC,Feuerer M,Opitz CA,Hopf C,Wick W,Platten M
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.
Nature communications
Chen L,Gibbons DL,Goswami S,Cortez MA,Ahn YH,Byers LA,Zhang X,Yi X,Dwyer D,Lin W,Diao L,Wang J,Roybal J,Patel M,Ungewiss C,Peng D,Antonia S,Mediavilla-Varela M,Robertson G,Suraokar M,Welsh JW,Erez B,Wistuba II,Chen L,Peng D,Wang S,Ullrich SE,Heymach JV,Kurie JM,Qin FX
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Flow Cytometry
Tue Oct 28 00:00:00 EDT 2014
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.
The Journal of experimental medicine
Ansari MJ,Salama AD,Chitnis T,Smith RN,Yagita H,Akiba H,Yamazaki T,Azuma M,Iwai H,Khoury SJ,Auchincloss H,Sayegh MH
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Immunohistochemistry
Mon Jul 07 00:00:00 EDT 2003
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.
The Journal of experimental medicine
Ansari MJ,Salama AD,Chitnis T,Smith RN,Yagita H,Akiba H,Yamazaki T,Azuma M,Iwai H,Khoury SJ,Auchincloss H,Sayegh MH
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Immunohistochemistry
Mon Jul 07 00:00:00 EDT 2003
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.
The Journal of experimental medicine
Ansari MJ,Salama AD,Chitnis T,Smith RN,Yagita H,Akiba H,Yamazaki T,Azuma M,Iwai H,Khoury SJ,Auchincloss H,Sayegh MH
Published figure using CD279 (PD-1) monoclonal antibody (Product # 48-9985-82) in Immunohistochemistry
Mon Jul 07 00:00:00 EDT 2003