Invitrogen

F4/80 Monoclonal Antibody (BM8), Super Bright™ 702, eBioscience™

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Antibody Testing Data (1)
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F4/80 Antibody (67-4801-82) in Flow

Staining of mouse resident peritoneal exudate cells with CD11b Monoclonal Antibody, PE (Product # 12-0112-82) and 0.5 µg of Rat IgG2a K Isotype Control, Super Bright 702 (Product # 67-4321-82) (left) or 0.5 µg of F4/80 Monoclonal Antibody, Super Bright 702 (right). Cells in the large scatter population were used for analysis.

F4/80 Antibody in Immunocytochemistry (ICC/IF)

F4/80 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

F4/80 Antibody in Immunohistochemistry (Frozen) (IHC (F))

F4/80 Antibody in Immunohistochemistry, Immunohistochemistry (Frozen) (IHC, IHC (F))

F4/80 Antibody in Immunohistochemistry (IHC)

F4/80 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

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Product Details

67-4801-82

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

View 48 publications 48 publications

Immunohistochemistry (Paraffin) (IHC (P))

View 3 publications 3 publications

Immunohistochemistry (PFA fixed) (IHC (PFA))

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

View 18 publications 18 publications

Flow Cytometry (Flow)

1.0 µg/test

View 68 publications 68 publications

Product Specifications

Species Reactivity

Mouse

Published species

Not Applicable

Host/Isotype

Rat / IgG2a, kappa

Recommended Isotype Control

Rat IgG2a kappa Isotype Control (eBR2a), Super Bright™ 702, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

BM8

Conjugate

Super Bright™ 702 Super Bright™ 702 Super Bright™ 702

Excitation/Emission Max

413/702 nm View spectra

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with BSA

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2717171

Product Specific Information

Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximately 160 kDa surface receptor. It belongs to the EGF-TM7 family of proteins. As such it contains seven EGF-like domains on its extracellular N-terminus, seven transmembrane spanning sequences, and an intracellular C-terminal domain showing homology to other TM7 superfamily members. The F4/80 antigen is expressed by a majority of mature macrophages and is one of the best markers for this population of cells. However, other cell types, such as peritoneal eosinophils, Langerhans cells, and some other dendritic cell subtypes, have been reported to express this antigen as well. Expression of F4/80 commences during early myeloid development in vivo and can be upregulated on BM cells stimulated in vitro with M-CSF. Some populations of macrophages, especially in the lymphoid microenvironment, may be devoid of F4/80.

Applications Reported: This BM8 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This BM8 antibody has been tested by flow cytometric analysis of mouse resident peritoneal exudate cells. This can be used at less than or equal to 1.0 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Super Bright 702 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 702 nm. We recommend using a 710/50 bandpass filter. Please make sure that your instrument is capable of detecting this fluorochrome.

When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (Product # SB-4401) to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information.

Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light.

Fixation: Samples can be stored in IC Fixation Buffer (Product # 00-8222) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product # 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.

Excitation: 405 nm; Emission: 702 nm; Laser: Violet Laser

Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company.

Target Information

F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

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eLife

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Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Fri Mar 24 00:00:00 EDT 2023

Role of low-intensity pulsed ultrasound in regulating macrophage polarization to accelerate tendon-bone interface repair.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Xu Z,Li S,Wan L,Hu J,Lu H,Zhang T

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2023

SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization.

Journal of advanced research

Lee JH,Lee SH,Lee EH,Cho JY,Song DK,Lee YJ,Kwon TK,Oh BC,Cho KW,Osborne TF,Jeon TI,Im SS

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

GPR84 regulates pulmonary inflammation by modulating neutrophil functions.

Acta pharmacologica Sinica

Wang SW,Zhang Q,Lu D,Fang YC,Yan XC,Chen J,Xia ZK,Yuan QT,Chen LH,Zhang YM,Nan FJ,Xie X

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2023

Overexpression of lipocalin 2 in PBX1-deficient decidual NK cells promotes inflammation at the maternal-fetal interface.

American journal of reproductive immunology (New York, N.Y. : 1989)

An X,Qin J,Hu X,Zhou Y,Fu B,Wei H

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2023

Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy.

Materials today. Bio

Huang J,Leng X,Jiang T,Xu L,Zheng J,Fang M,Wang J,Wang Z,Zhang L

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Sat Apr 01 00:00:00 EDT 2023

Low-intensity pulsed ultrasound promotes skeletal muscle regeneration via modulating the inflammatory immune microenvironment.

International journal of biological sciences

Qin H,Luo Z,Sun Y,He Z,Qi B,Chen Y,Wang J,Li C,Lin W,Han Z,Zhu Y

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Mar 20 00:00:00 EDT 2023

CD146 Associates with Gp130 to Control a Macrophage Pro-inflammatory Program That Regulates the Metabolic Response to Obesity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Duan H,Jing L,Xiang J,Ju C,Wu Z,Liu J,Ma X,Chen X,Liu Z,Feng J,Yan X

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2022

Streptococcus agalactiae cadD alleviates metal stress and promotes intracellular survival in macrophages and ascending infection during pregnancy.

Nature communications

Korir ML,Doster RS,Lu J,Guevara MA,Spicer SK,Moore RE,Francis JD,Rogers LM,Haley KP,Blackman A,Noble KN,Eastman AJ,Williams JA,Damo SM,Boyd KL,Townsend SD,Henrique Serezani C,Aronoff DM,Manning SD,Gaddy JA

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Wed Sep 14 00:00:00 EDT 2022

Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice.

Nature communications

Weber AA,Yang X,Mennillo E,Ding J,Watrous JD,Jain M,Chen S,Karin M,Tukey RH

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Wed Jul 27 00:00:00 EDT 2022

Role of circular RNA cdr1as in modulation of macrophage phenotype.

Life sciences

Gonzalez C,Cimini M,Cheng Z,Benedict C,Wang C,Trungcao M,Mallaredy V,Rajan S,Garikipati VNS,Kishore R

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Nov 15 00:00:00 EST 2022

Wound healing in aged skin exhibits systems-level alterations in cellular composition and cell-cell communication.

Cell reports

Vu R,Jin S,Sun P,Haensel D,Nguyen QH,Dragan M,Kessenbrock K,Nie Q,Dai X

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Aug 02 00:00:00 EDT 2022

PDGF-D activation by macrophage-derived uPA promotes AngII-induced cardiac remodeling in obese mice.

The Journal of experimental medicine

Cheng YW,Zhang ZB,Lan BD,Lin JR,Chen XH,Kong LR,Xu L,Ruan CC,Gao PJ

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Sep 06 00:00:00 EDT 2021

A bilirubin-derived nanomedicine attenuates the pathological cascade of pulmonary fibrosis.

Biomaterials

Keum H,Kim D,Kim J,Kim TW,Whang CH,Jung W,Jon S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Sun Aug 01 00:00:00 EDT 2021

Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling.

The EMBO journal

Wieghofer P,Hagemeyer N,Sankowski R,Schlecht A,Staszewski O,Amann L,Gruber M,Koch J,Hausmann A,Zhang P,Boneva S,Masuda T,Hilgendorf I,Goldmann T,Böttcher C,Priller J,Rossi FM,Lange C,Prinz M

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Mar 15 00:00:00 EDT 2021

Tumor- and osteoclast-derived NRP2 in prostate cancer bone metastases.

Bone research

Polavaram NS,Dutta S,Islam R,Bag AK,Roy S,Poitz D,Karnes J,Hofbauer LC,Kohli M,Costello BA,Jimenez R,Batra SK,Teply BA,Muders MH,Datta K

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Fri May 14 00:00:00 EDT 2021

Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects.

Basic research in cardiology

Frenis K,Helmstädter J,Ruan Y,Schramm E,Kalinovic S,Kröller-Schön S,Bayo Jimenez MT,Hahad O,Oelze M,Jiang S,Wenzel P,Sommer CJ,Frauenknecht KBM,Waisman A,Gericke A,Daiber A,Münzel T,Steven S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Fri Apr 30 00:00:00 EDT 2021

Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice.

Cell death and differentiation

Jiang Y,Tang Y,Hoover C,Kondo Y,Huang D,Restagno D,Shao B,Gao L,Michael McDaniel J,Zhou M,Silasi-Mansat R,McGee S,Jiang M,Bai X,Lupu F,Ruan C,Marth JD,Wu D,Han Y,Xia L

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Mon Nov 01 00:00:00 EDT 2021

Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice.

Cell death and differentiation

Jiang Y,Tang Y,Hoover C,Kondo Y,Huang D,Restagno D,Shao B,Gao L,Michael McDaniel J,Zhou M,Silasi-Mansat R,McGee S,Jiang M,Bai X,Lupu F,Ruan C,Marth JD,Wu D,Han Y,Xia L

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Mon Nov 01 00:00:00 EDT 2021

Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation.

Diabetes

Jin Y,Ji Y,Song Y,Choe SS,Jeon YG,Na H,Nam TW,Kim HJ,Nahmgoong H,Kim SM,Kim JW,Nam KT,Seong JK,Hwang D,Park CB,Lee IH,Kim JB,Lee HW

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2021

Interleukin 6 regulates the expression of programmed cell death ligand 1 in thyroid cancer.

Cancer science

Zhang GQ,Jiao Q,Shen CT,Song HJ,Zhang HZ,Qiu ZL,Luo QY

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Mar 01 00:00:00 EST 2021

Potential functions of embryonic cardiac macrophages in angiogenesis, lymphangiogenesis and extracellular matrix remodeling.

Histochemistry and cell biology

Gula G,Rumiński S,Niderla-Bielińska J,Jasińska A,Kiernozek E,Jankowska-Steifer E,Flaht-Zabost A,Ratajska A

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Fri Jan 01 00:00:00 EST 2021

Assessment of ¹⁸F-PBR-111 in the Cuprizone Mouse Model of Multiple Sclerosis.

Diagnostics (Basel, Switzerland)

Jewells VL,Yuan H,Merrill JR,Frank JE,Patel A,Cohen SM,Giglio B,Feinberg NN,Matsushima GK,Li Z

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Tue Apr 27 00:00:00 EDT 2021

Assessment of ¹⁸F-PBR-111 in the Cuprizone Mouse Model of Multiple Sclerosis.

Diagnostics (Basel, Switzerland)

Jewells VL,Yuan H,Merrill JR,Frank JE,Patel A,Cohen SM,Giglio B,Feinberg NN,Matsushima GK,Li Z

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Tue Apr 27 00:00:00 EDT 2021

IL-19 Contributes to the Development of Nonalcoholic Steatohepatitis by Altering Lipid Metabolism.

Cells

Azuma YT,Fujita T,Izawa T,Hirota K,Nishiyama K,Ikegami A,Aoyama T,Ike M,Ushikai Y,Kuwamura M,Fujii H,Tsuneyama K

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Mon Dec 13 00:00:00 EST 2021

Decreased ferroportin in hepatocytes promotes macrophages polarize towards an M2-like phenotype and liver fibrosis.

Scientific reports

Cai C,Zeng D,Gao Q,Ma L,Zeng B,Zhou Y,Wang H

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Mon Jun 28 00:00:00 EDT 2021

Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.

Biology

Hridi SU,Barbour M,Wilson C,Franssen AJ,Harte T,Bushell TJ,Jiang HR

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry (Frozen)

Thu May 27 00:00:00 EDT 2021

Complement-5 Inhibition Deters Progression of Fulminant Hepatitis to Acute Liver Failure in Murine Models.

Cellular and molecular gastroenterology and hepatology

Kusakabe J,Hata K,Miyauchi H,Tajima T,Wang Y,Tamaki I,Kawasoe J,Okamura Y,Zhao X,Okamoto T,Tsuruyama T,Uemoto S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Tue Mar 08 00:00:00 EST 2022

Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment.

eLife

Shan Z,Li L,Atkins CL,Wang M,Wen Y,Jeong J,Moreno NF,Feng D,Gui X,Zhang N,Lee CG,Elias JA,Lee WM,Gao B,Lam FW,An Z,Ju C

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Thu Jun 10 00:00:00 EDT 2021

Thymopentin treatment of murine premature ovarian failure via attenuation of immune cell activity and promotion of the BMP4/Smad9 signalling pathway.

International journal of medical sciences

Zhu X,Liu J,Pan H,Geng Z,Huang W,Liu T,Zhang B

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Tue Mar 15 00:00:00 EDT 2022

Treatment with the Probiotic Product Aviguard^® Alleviates Inflammatory Responses during Campylobacter jejuni-Induced Acute Enterocolitis in Mice.

International journal of molecular sciences

Heimesaat MM,Weschka D,Mousavi S,Bereswill S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Tue Jun 22 00:00:00 EDT 2021

Peroral Clove Essential Oil Treatment Ameliorates Acute Campylobacteriosis-Results from a Preclinical Murine Intervention Study.

Microorganisms

Bereswill S,Mousavi S,Weschka D,Buczkowski A,Schmidt S,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Wed Mar 31 00:00:00 EDT 2021

Nonalcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet.

Cellular and molecular gastroenterology and hepatology

Ganguly S,Muench GA,Shang L,Rosenthal SB,Rahman G,Wang R,Wang Y,Kwon HC,Diomino AM,Kisseleva T,Soorosh P,Hosseini M,Knight R,Schnabl B,Brenner DA,Dhar D

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Tue Mar 22 00:00:00 EDT 2022

Disease-Alleviating Effects of Peroral Activated Charcoal Treatment in Acute Murine Campylobacteriosis.

Microorganisms

Bereswill S,Mousavi S,Weschka D,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Wed Jun 30 00:00:00 EDT 2021

Evidence of a Myenteric Plexus Barrier and Its Macrophage-Dependent Degradation During Murine Colitis: Implications in Enteric Neuroinflammation.

Cellular and molecular gastroenterology and hepatology

Dora D,Ferenczi S,Stavely R,Toth VE,Varga ZV,Kovacs T,Bodi I,Hotta R,Kovacs KJ,Goldstein AM,Nagy N

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Mon Mar 28 00:00:00 EDT 2022

Evidence of a Myenteric Plexus Barrier and Its Macrophage-Dependent Degradation During Murine Colitis: Implications in Enteric Neuroinflammation.

Cellular and molecular gastroenterology and hepatology

Dora D,Ferenczi S,Stavely R,Toth VE,Varga ZV,Kovacs T,Bodi I,Hotta R,Kovacs KJ,Goldstein AM,Nagy N

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Mon Mar 28 00:00:00 EDT 2022

Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.

Frontiers in immunology

Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Feb 10 00:00:00 EST 2022

Characterisation of Macrophage Polarisation in Mice Infected with Ninoa Strain of Trypanosoma cruzi.

Pathogens (Basel, Switzerland)

Medina-Buelvas DM,Rodríguez-Sosa M,Vega L

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Sat Nov 06 00:00:00 EDT 2021

Topical arginase inhibition decreases growth of cutaneous squamous cell carcinoma.

Scientific reports

Mittal A,Wang M,Vidyarthi A,Yanez D,Pizzurro G,Thakral D,Tracy E,Colegio OR

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon May 24 00:00:00 EDT 2021

Comprehensive analysis of liver macrophage composition by flow cytometry and immunofluorescence in murine NASH.

STAR protocols

Daemen S,Chan MM,Schilling JD

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Fri Jun 18 00:00:00 EDT 2021

Generation and utilization of a HEK-293T murine GM-CSF expressing cell line.

PloS one

Robinson EK,Covarrubias S,Zhou S,Carpenter S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Wed Sep 15 00:00:00 EDT 2021

Acute Inflammatory Response in Osteoporotic Fracture Healing Augmented with Mechanical Stimulation is Regulated In Vivo through the p38-MAPK Pathway.

International journal of molecular sciences

Chow SKH,Cui C,Cheng KYK,Chim YN,Wang J,Wong CHW,Ng KW,Wong RMY,Cheung WH

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Fri Aug 13 00:00:00 EDT 2021

Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.

Journal of neuroinflammation

Oladiran O,Shi XQ,Yang M,Fournier S,Zhang J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Mar 22 00:00:00 EDT 2021

STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.

Cellular and molecular gastroenterology and hepatology

Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Jan 24 00:00:00 EST 2022

CX3CR1 But Not CCR2 Expression Is Required for the Development of Autoimmune Peripheral Neuropathy in Mice.

Frontiers in immunology

Oladiran O,Shi XQ,Fournier S,Zhang J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Dec 21 00:00:00 EST 2021

Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.

Nano-micro letters

Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Sat Nov 21 00:00:00 EST 2020

Chronic mTOR activation induces a degradative smooth muscle cell phenotype.

The Journal of clinical investigation

Li G,Wang M,Caulk AW,Cilfone NA,Gujja S,Qin L,Chen PY,Chen Z,Yousef S,Jiao Y,He C,Jiang B,Korneva A,Bersi MR,Wang G,Liu X,Mehta S,Geirsson A,Gulcher JR,Chittenden TW,Simons M,Humphrey JD,Tellides G

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Mon Mar 02 00:00:00 EST 2020

Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage-myofibroblast transition.

Proceedings of the National Academy of Sciences of the United States of America

Tang PM,Zhang YY,Xiao J,Tang PC,Chung JY,Li J,Xue VW,Huang XR,Chong CC,Ng CF,Lee TL,To KF,Nikolic-Paterson DJ,Lan HY

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Tue Aug 25 00:00:00 EDT 2020

Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage-myofibroblast transition.

Proceedings of the National Academy of Sciences of the United States of America

Tang PM,Zhang YY,Xiao J,Tang PC,Chung JY,Li J,Xue VW,Huang XR,Chong CC,Ng CF,Lee TL,To KF,Nikolic-Paterson DJ,Lan HY

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Tue Aug 25 00:00:00 EDT 2020

Absence of Bsep/Abcb11 attenuates MCD diet-induced hepatic steatosis but aggravates inflammation in mice.

Liver international : official journal of the International Association for the Study of the Liver

Fuchs CD,Krivanec S,Steinacher D,Mlitz V,Wahlström A,Stahlman M,Claudel T,Scharnagl H,Stojakovic T,Marschall HU,Trauner M

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Mon Jun 01 00:00:00 EDT 2020

Spatial proteomics revealed a CX₃CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder.

Mucosal immunology

Bottek J,Soun C,Lill JK,Dixit A,Thiebes S,Beerlage AL,Horstmann M,Urbanek A,Heuer H,Uszkoreit J,Eisenacher M,Bracht T,Sitek B,Hoffmann F,Vijitha N,von Eggeling F,Engel DR

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry (Frozen)

Wed Jul 01 00:00:00 EDT 2020

Spatial proteomics revealed a CX₃CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder.

Mucosal immunology

Bottek J,Soun C,Lill JK,Dixit A,Thiebes S,Beerlage AL,Horstmann M,Urbanek A,Heuer H,Uszkoreit J,Eisenacher M,Bracht T,Sitek B,Hoffmann F,Vijitha N,von Eggeling F,Engel DR

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry (Frozen)

Wed Jul 01 00:00:00 EDT 2020

Macrophage GIT1 Contributes to Bone Regeneration by Regulating Inflammatory Responses in an ERK/NRF2-Dependent Way.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Zhao SJ,Liu H,Chen J,Qian DF,Kong FQ,Jie J,Yin GY,Li QQ,Fan J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Neonatal Heart Responds to Pressure Overload With Differential Alterations in Various Cardiomyocyte Maturation Programs That Accommodate Simultaneous Hypertrophy and Hyperplasia.

Frontiers in cell and developmental biology

Ding X,Wang S,Wang Y,Yang J,Bao N,Liu J,Zhang Z

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Fri Dec 18 00:00:00 EST 2020

Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K/AKT/GSK3β/β-catenin pathway.

Theranostics

Zhao SJ,Kong FQ,Jie J,Li Q,Liu H,Xu AD,Yang YQ,Jiang B,Wang DD,Zhou ZQ,Tang PY,Chen J,Wang Q,Zhou Z,Chen Q,Yin GY,Zhang HW,Fan J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry (PFA fixed)

Fri Apr 02 00:00:00 EDT 2021

Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K/AKT/GSK3β/β-catenin pathway.

Theranostics

Zhao SJ,Kong FQ,Jie J,Li Q,Liu H,Xu AD,Yang YQ,Jiang B,Wang DD,Zhou ZQ,Tang PY,Chen J,Wang Q,Zhou Z,Chen Q,Yin GY,Zhang HW,Fan J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry (PFA fixed)

Fri Apr 02 00:00:00 EDT 2021

Orf Virus IL-10 and VEGF-E Act Synergistically to Enhance Healing of Cutaneous Wounds in Mice.

Journal of clinical medicine

Wise LM,Stuart GS,Jones NC,Fleming SB,Mercer AA

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Sat Apr 11 00:00:00 EDT 2020

Nanochannel-Based Poration Drives Benign and Effective Nonviral Gene Delivery to Peripheral Nerve Tissue.

Advanced biosystems

Moore JT,Wier CG,Lemmerman LR,Ortega-Pineda L,Dodd DJ,Lawrence WR,Duarte-Sanmiguel S,Dathathreya K,Diaz-Starokozheva L,Harris HN,Sen CK,Valerio IL,Higuita-Castro N,Arnold WD,Kolb SJ,Gallego-Perez D

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Sun Nov 01 00:00:00 EDT 2020

Preclinical Evaluation of Oral Urolithin-A for the Treatment of Acute Campylobacteriosis in Campylobacter jejuni Infected Microbiota-Depleted IL-10^-/- Mice.

Pathogens (Basel, Switzerland)

Mousavi S,Weschka D,Bereswill S,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Wed Dec 23 00:00:00 EST 2020

Immune-modulatory Properties of the Octapeptide NAP in Campylobacter jejuni Infected Mice Suffering from Acute Enterocolitis.

Microorganisms

Heimesaat MM,Mousavi S,Kløve S,Genger C,Weschka D,Giladi E,Bereswill S,Gozes I

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Tue May 26 00:00:00 EDT 2020

Inhibition of Yes-Associated Protein by Verteporfin Ameliorates Unilateral Ureteral Obstruction-Induced Renal Tubulointerstitial Inflammation and Fibrosis.

International journal of molecular sciences

Jin J,Wang T,Park W,Li W,Kim W,Park SK,Kang KP

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Sat Oct 31 00:00:00 EDT 2020

Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury.

Journal of neuroinflammation

Kong FQ,Zhao SJ,Sun P,Liu H,Jie J,Xu T,Xu AD,Yang YQ,Zhu Y,Chen J,Zhou Z,Qian DF,Gu CJ,Chen Q,Yin GY,Zhang HW,Fan J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Mon Feb 17 00:00:00 EST 2020

Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury.

Journal of neuroinflammation

Kong FQ,Zhao SJ,Sun P,Liu H,Jie J,Xu T,Xu AD,Yang YQ,Zhu Y,Chen J,Zhou Z,Qian DF,Gu CJ,Chen Q,Yin GY,Zhang HW,Fan J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Mon Feb 17 00:00:00 EST 2020

Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1.

Nature metabolism

Brett JO,Arjona M,Ikeda M,Quarta M,de Morrée A,Egner IM,Perandini LA,Ishak HD,Goshayeshi A,Benjamin DI,Both P,Rodríguez-Mateo C,Betley MJ,Wyss-Coray T,Rando TA

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Wed Apr 01 00:00:00 EDT 2020

Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype.

International journal of molecular sciences

Pavlović N,Kopsida M,Gerwins P,Heindryckx F

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Sat Oct 31 00:00:00 EDT 2020

Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses.

Cell reports

Blagih J,Zani F,Chakravarty P,Hennequart M,Pilley S,Hobor S,Hock AK,Walton JB,Morton JP,Gronroos E,Mason S,Yang M,McNeish I,Swanton C,Blyth K,Vousden KH

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Tue Jan 14 00:00:00 EST 2020

Modulated Electro-Hyperthermia-Induced Tumor Damage Mechanisms Revealed in Cancer Models.

International journal of molecular sciences

Krenacs T,Meggyeshazi N,Forika G,Kiss E,Hamar P,Szekely T,Vancsik T

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Sat Aug 29 00:00:00 EDT 2020

Prodrug-Loaded Zirconium Carbide Nanosheets as a Novel Biophotonic Nanoplatform for Effective Treatment of Cancer.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Liu Q,Xie Z,Qiu M,Shim I,Yang Y,Xie S,Yang Q,Wang D,Chen S,Fan T,Ding B,Guo Z,Adah D,Yao X,Zhang Y,Wu H,Wu Z,Wei C,Wang H,Kim HS,Zou Q,Yan Q,Cai Z,Kim JS,Liu LP,Zhang H,Cao Y

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Tue Dec 01 00:00:00 EST 2020

CTNNB1/β-catenin dysfunction contributes to adiposity by regulating the cross-talk of mature adipocytes and preadipocytes.

Science advances

Chen M,Lu P,Ma Q,Cao Y,Chen N,Li W,Zhao S,Chen B,Shi J,Sun Y,Shen H,Sun L,Shen J,Liao Q,Zhang Y,Hong J,Gu W,Liu R,Ning G,Wang W,Wang J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

Differential Activation of Macrophages Based on Their Environment in Advanced Age.

Chonnam medical journal

Lee DY,Lim JS,Cho KA

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model.

Scientific reports

Bonfanti AP,Barreto N,Munhoz J,Caballero M,Cordeiro G,Rocha-E-Silva T,Sutti R,Moura F,Brunetto S,Ramos CD,Thomé R,Verinaud L,Rapôso C

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Fri Apr 03 00:00:00 EDT 2020

High-salt diet decreases mechanical thresholds in mice that is mediated by a CCR2-dependent mechanism.

Journal of neuroinflammation

Fan A,Oladiran O,Shi XQ,Zhang J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Jun 09 00:00:00 EDT 2020

Analysis of Myeloid Cells in Mouse Tissues with Flow Cytometry.

STAR protocols

Liu Z,Gu Y,Shin A,Zhang S,Ginhoux F

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Fri Jun 19 00:00:00 EDT 2020

Macrophage-Associated Lipin-1 Promotes β-Oxidation in Response to Proresolving Stimuli.

ImmunoHorizons

Schilke RM,Blackburn CMR,Rao S,Krzywanski DM,Finck BN,Woolard MD

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Oct 19 00:00:00 EDT 2020

Host deficiency in ephrin-A1 inhibits breast cancer metastasis.

F1000Research

Shiuan E,Inala A,Wang S,Song W,Youngblood V,Chen J,Brantley-Sieders DM

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2021

MFG-E8 accelerates wound healing in diabetes by regulating "NLRP3 inflammasome-neutrophil extracellular traps" axis.

Cell death discovery

Huang W,Jiao J,Liu J,Huang M,Hu Y,Ran W,Yan L,Xiong Y,Li M,Quan Z,Rao Y,Chen J,Huang Y,Zhang D

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Sep 26 00:00:00 EDT 2023

Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer.

Journal of hematology & oncology

Lu CS,Shiau AL,Su BH,Hsu TS,Wang CT,Su YC,Tsai MS,Feng YH,Tseng YL,Yen YT,Wu CL,Shieh GS

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2020

Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells.

JCI insight

Hadas R,Gershon E,Cohen A,Atrakchi O,Lazar S,Golani O,Dassa B,Elbaz M,Cohen G,Eilam R,Dekel N,Neeman M

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Nov 19 00:00:00 EST 2020

Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.

eLife

Kim EH,Woodruff MC,Grigoryan L,Maier B,Lee SH,Mandal P,Cortese M,Natrajan MS,Ravindran R,Ma H,Merad M,Gitlin AD,Mocarski ES,Jacob J,Pulendran B

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Jun 09 00:00:00 EDT 2020

Inhibition of Fatty Acid-Binding Protein 4 Attenuated Kidney Fibrosis by Mediating Macrophage-to-Myofibroblast Transition.

Frontiers in immunology

Feng Y,Guo F,Xia Z,Liu J,Mai H,Liang Y,Zhu G,Li Y,Bai L,Li L,Huang R,Shi M,Ma L,Fu P

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Jun 03 00:00:00 EDT 2021

Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.

Cells

Nuti E,Rossello A,Cuffaro D,Camodeca C,Van Bael J,van der Maat D,Martens E,Fiten P,Pereira RVS,Ugarte-Berzal E,Gouwy M,Opdenakker G,Vandooren J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Jul 07 00:00:00 EDT 2020

Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression.

Nature communications

Yu L,Zhang B,Deochand D,Sacta MA,Coppo M,Shang Y,Guo Z,Zeng X,Rollins DA,Tharmalingam B,Li R,Chinenov Y,Rogatsky I,Hu X

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Fri May 08 00:00:00 EDT 2020

Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.

Cell & bioscience

Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Apr 14 00:00:00 EDT 2022

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.

Nature

Escolano A,Gristick HB,Abernathy ME,Merkenschlager J,Gautam R,Oliveira TY,Pai J,West AP,Barnes CO,Cohen AA,Wang H,Golijanin J,Yost D,Keeffe JR,Wang Z,Zhao P,Yao KH,Bauer J,Nogueira L,Gao H,Voll AV,Montefiori DC,Seaman MS,Gazumyan A,Silva M,McGuire AT,Stamatatos L,Irvine DJ,Wells L,Martin MA,Bjorkman PJ,Nussenzweig MC

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Sat Jun 01 00:00:00 EDT 2019

NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD.

Hepatology (Baltimore, Md.)

Ohashi K,Wang Z,Yang YM,Billet S,Tu W,Pimienta M,Cassel SL,Pandol SJ,Lu SC,Sutterwala FS,Bhowmick N,Seki E

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Fri Nov 01 00:00:00 EDT 2019

Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.

Anti-cancer drugs

Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

Murine Fecal Microbiota Transplantation Alleviates Intestinal and Systemic Immune Responses in Campylobacter jejuni Infected Mice Harboring a Human Gut Microbiota.

Frontiers in immunology

Heimesaat MM,Mrazek K,Bereswill S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Mon Oct 26 00:00:00 EDT 2020

Murine Fecal Microbiota Transplantation Alleviates Intestinal and Systemic Immune Responses in Campylobacter jejuni Infected Mice Harboring a Human Gut Microbiota.

Frontiers in immunology

Heimesaat MM,Mrazek K,Bereswill S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Mon Oct 26 00:00:00 EDT 2020

Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes.

EBioMedicine

Bai J,Gao Y,Chen L,Yin Q,Lou F,Wang Z,Xu Z,Zhou H,Li Q,Cai W,Sun Y,Niu L,Wang H,Wei Z,Lu S,Zhou A,Zhang J,Wang H

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Tue Jan 01 00:00:00 EST 2019

A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma.

Journal of clinical medicine

Kurelac I,Abarrategi A,Ragazzi M,Iommarini L,Umesh Ganesh N,Snoeks T,Bonnet D,Porcelli AM,Malanchi I,Gasparre G

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Wed Dec 11 00:00:00 EST 2019

Depletion of RIPK1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis.

Cell death & disease

Farooq M,Filliol A,Simoes Eugénio M,Piquet-Pellorce C,Dion S,Raguenes-Nicol C,Jan A,Dimanche-Boitrel MT,Le Seyec J,Samson M

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Tue Jan 08 00:00:00 EST 2019

Therapeutic ultrasound attenuates DSS-induced colitis through the cholinergic anti-inflammatory pathway.

EBioMedicine

Nunes NS,Chandran P,Sundby M,Visioli F,da Costa Gonçalves F,Burks SR,Paz AH,Frank JA

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Jul 01 00:00:00 EDT 2019

Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth.

Nature communications

Kusano T,Ehirchiou D,Matsumura T,Chobaz V,Nasi S,Castelblanco M,So A,Lavanchy C,Acha-Orbea H,Nishino T,Okamoto K,Busso N

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Oct 28 00:00:00 EDT 2019

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.

Nature

Morioka S,Perry JSA,Raymond MH,Medina CB,Zhu Y,Zhao L,Serbulea V,Onengut-Gumuscu S,Leitinger N,Kucenas S,Rathmell JC,Makowski L,Ravichandran KS

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Nov 01 00:00:00 EDT 2018

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.

Cell

Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Jun 28 00:00:00 EDT 2018

The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis.

Cell host & microbe

Truax AD,Chen L,Tam JW,Cheng N,Guo H,Koblansky AA,Chou WC,Wilson JE,Brickey WJ,Petrucelli A,Liu R,Cooper DE,Koenigsknecht MJ,Young VB,Netea MG,Stienstra R,Sartor RB,Montgomery SA,Coleman RA,Ting JP

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Wed Sep 12 00:00:00 EDT 2018

Myeloid p38α signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis.

EMBO molecular medicine

Youssif C,Cubillos-Rojas M,Comalada M,Llonch E,Perna C,Djouder N,Nebreda AR

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Sun Jul 01 00:00:00 EDT 2018

Myeloid p38α signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis.

EMBO molecular medicine

Youssif C,Cubillos-Rojas M,Comalada M,Llonch E,Perna C,Djouder N,Nebreda AR

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Sun Jul 01 00:00:00 EDT 2018

Frontline Science: Macrophage-derived exosomes promote neutrophil necroptosis following hemorrhagic shock.

Journal of leukocyte biology

Jiao Y,Li Z,Loughran PA,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Shi X,Fan J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

Sustained Delivery of Doxorubicin via Acetalated Dextran Scaffold Prevents Glioblastoma Recurrence after Surgical Resection.

Molecular pharmaceutics

Graham-Gurysh E,Moore KM,Satterlee AB,Sheets KT,Lin FC,Bachelder EM,Miller CR,Hingtgen SD,Ainslie KM

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Mon Mar 05 00:00:00 EST 2018

Evaluation of renal metabolic response to partial ureteral obstruction with hyperpolarized ¹³ C MRI.

NMR in biomedicine

Niles DJ,Gordon JW,Huang G,Reese S,Adamson EB,Djamali A,Fain SB

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry (Paraffin)

Mon Jan 01 00:00:00 EST 2018

Yap/Taz mediates mTORC2-stimulated fibroblast activation and kidney fibrosis.

The Journal of biological chemistry

Gui Y,Li J,Lu Q,Feng Y,Wang M,He W,Yang J,Dai C

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry (Frozen)

Fri Oct 19 00:00:00 EDT 2018

Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice.

Theranostics

Li X,Jia L,Chen X,Dong Y,Ren X,Dong Y,Chen Y,Xie L,Liu M,Shiota C,Gittes GK,Rui L,Chen Z

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Thu Sep 05 00:00:00 EDT 2019

Differentiated macrophages acquire a pro-inflammatory and cell death-resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1.

The Journal of biological chemistry

Rijal D,Ariana A,Wight A,Kim K,Alturki NA,Aamir Z,Ametepe ES,Korneluk RG,Tiedje C,Menon MB,Gaestel M,McComb S,Sad S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Fri Jul 27 00:00:00 EDT 2018

BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells.

Oncotarget

Romano E,Rufo N,Korf H,Mathieu C,Garg AD,Agostinis P

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Apr 03 00:00:00 EDT 2018

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity.

The Journal of experimental medicine

Thomas DC,Clare S,Sowerby JM,Pardo M,Juss JK,Goulding DA,van der Weyden L,Storisteanu D,Prakash A,Espéli M,Flint S,Lee JC,Hoenderdos K,Kane L,Harcourt K,Mukhopadhyay S,Umrania Y,Antrobus R,Nathan JA,Adams DJ,Bateman A,Choudhary JS,Lyons PA,Condliffe AM,Chilvers ER,Dougan G,Smith KG

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Apr 03 00:00:00 EDT 2017

(Pro)renin Receptor Is an Amplifier of Wnt/β-Catenin Signaling in Kidney Injury and Fibrosis.

Journal of the American Society of Nephrology : JASN

Li Z,Zhou L,Wang Y,Miao J,Hong X,Hou FF,Liu Y

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Tue Aug 01 00:00:00 EDT 2017

RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.

EMBO molecular medicine

Zhu H,Lou F,Yin Q,Gao Y,Sun Y,Bai J,Xu Z,Liu Z,Cai W,Ke F,Zhang L,Zhou H,Wang H,Wang G,Chen X,Zhang H,Wang Z,Ginhoux F,Lu C,Su B,Wang H

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

Rictor/mammalian target of rapamycin complex 2 promotes macrophage activation and kidney fibrosis.

The Journal of pathology

Ren J,Li J,Feng Y,Shu B,Gui Y,Wei W,He W,Yang J,Dai C

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Tue Aug 01 00:00:00 EDT 2017

1,25-Dihydroxyvitamin D Inhibits LPS-Induced High-Mobility Group Box 1 (HMGB1) Secretion via Targeting the NF-E2-Related Factor 2-Hemeoxygenase-1-HMGB1 Pathway in Macrophages.

Frontiers in immunology

Rao Z,Zhang N,Xu N,Pan Y,Xiao M,Wu J,Zhou H,Yang S,Chen Y

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Wed Nov 20 00:00:00 EST 2019

The Second-Generation PGI2 Analogue Treprostinil Fails to Chemoprevent Tumors in a Murine Lung Adenocarcinoma Model.

Cancer prevention research (Philadelphia, Pa.)

Dwyer-Nield L,Hickey GA,Friedman M,Choo K,McArthur DG,Tennis MA,New ML,Geraci M,Keith RL

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Wed Nov 01 00:00:00 EDT 2017

Phenotypic switch in lung interstitial macrophage polarization in an ovalbumin-induced mouse model of asthma.

Experimental and therapeutic medicine

Nie H,Wang A,He Q,Yang Q,Liu L,Zhang G,Huang Y,Ding X,Yu H,Hu S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Aug 01 00:00:00 EDT 2017

PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy.

Scientific reports

Gao S,Li C,Zhu Y,Wang Y,Sui A,Zhong Y,Xie B,Shen X

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Fri Feb 17 00:00:00 EST 2017

Omega-3 Polyunsaturated Fatty Acids Attenuate Fibroblast Activation and Kidney Fibrosis Involving MTORC2 Signaling Suppression.

Scientific reports

Zeng Z,Yang H,Wang Y,Ren J,Dai Y,Dai C

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Mon Apr 10 00:00:00 EDT 2017

Inhibitory effect of silymarin on CCl₄-induced liver fibrosis by reducing Ly6C^hi monocytes infiltration.

International journal of clinical and experimental pathology

Zhao XA,Chen GM,Liu Y,Chen YX,Wu HY,Chen J,Xiong YL,Tian C,Wang GY,Jia B,Xia J,Wang J,Yan XM,Zhang ZP,Huang R,Wu C

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Sun Jan 26 00:00:00 EST 2020

One Year Follow-Up Risk Assessment in SKH-1 Mice and Wounds Treated with an Argon Plasma Jet.

International journal of molecular sciences

Schmidt A,Woedtke TV,Stenzel J,Lindner T,Polei S,Vollmar B,Bekeschus S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Wed Apr 19 00:00:00 EDT 2017

The role of human cytochrome P450 2E1 in liver inflammation and fibrosis.

Hepatology communications

Xu J,Ma HY,Liang S,Sun M,Karin G,Koyama Y,Hu R,Quehenberger O,Davidson NO,Dennis EA,Kisseleva T,Brenner DA

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Fri Dec 01 00:00:00 EST 2017

Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.

PloS one

Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Mon Sep 18 00:00:00 EDT 2017

Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.

Immunology

Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Sat Oct 01 00:00:00 EDT 2016

Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD.

Journal of lipid research

Chattopadhyay A,Navab M,Hough G,Grijalva V,Mukherjee P,Fogelman HR,Hwang LH,Faull KF,Lusis AJ,Reddy ST,Fogelman AM

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes.

Journal of leukocyte biology

Lagassé HA,Anidi IU,Craig JM,Limjunyawong N,Poupore AK,Mitzner W,Scott AL

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Periostin (POSTN) Regulates Tumor Resistance to Antiangiogenic Therapy in Glioma Models.

Molecular cancer therapeutics

Park SY,Piao Y,Jeong KJ,Dong J,de Groot JF

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Thu Sep 01 00:00:00 EDT 2016

Low intensity vibration mitigates tumor progression and protects bone quantity and quality in a murine model of myeloma.

Bone

Pagnotti GM,Chan ME,Adler BJ,Shroyer KR,Rubin J,Bain SD,Rubin CT

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Temporal and spatial distribution of macrophage phenotype markers in the foreign body response to glutaraldehyde-crosslinked gelatin hydrogels.

Journal of biomaterials science. Polymer edition

Yu T,Wang W,Nassiri S,Kwan T,Dang C,Liu W,Spiller KL

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Thu Dec 29 00:00:00 EST 2016

NADPH Oxidases Are Essential for Macrophage Differentiation.

The Journal of biological chemistry

Xu Q,Choksi S,Qu J,Jang J,Choe M,Banfi B,Engelhardt JF,Liu ZG

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Fri Sep 16 00:00:00 EDT 2016

NADPH Oxidases Are Essential for Macrophage Differentiation.

The Journal of biological chemistry

Xu Q,Choksi S,Qu J,Jang J,Choe M,Banfi B,Engelhardt JF,Liu ZG

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Fri Sep 16 00:00:00 EDT 2016

PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice.

Cell death & disease

Wang T,Wang Z,Yang P,Xia L,Zhou M,Wang S,Du J,Zhang J

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Apr 07 00:00:00 EDT 2016

EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta.

Scientific reports

Chen II,Caprioli A,Ohnuki H,Kwak H,Porcher C,Tosato G

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Jun 02 00:00:00 EDT 2016

SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL.

Autophagy

Choi SH,Gonen A,Diehl CJ,Kim J,Almazan F,Witztum JL,Miller YI

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Feb 23 00:00:00 EST 2016

Hedgehog signaling indirectly affects tubular cell survival after obstructive kidney injury.

American journal of physiology. Renal physiology

Rauhauser AA,Ren C,Lu D,Li B,Zhu J,McEnery K,Vadnagara K,Zepeda-Orozco D,Zhou XJ,Lin F,Jetten AM,Attanasio M

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Sun Nov 01 00:00:00 EDT 2015

Chemokine receptor Cxcr4 contributes to kidney fibrosis via multiple effectors.

American journal of physiology. Renal physiology

Yuan A,Lee Y,Choi U,Moeckel G,Karihaloo A

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2015

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.

Nature

Colegio OR,Chu NQ,Szabo AL,Chu T,Rhebergen AM,Jairam V,Cyrus N,Brokowski CE,Eisenbarth SC,Phillips GM,Cline GW,Phillips AJ,Medzhitov R

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Sep 25 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Thu May 01 00:00:00 EDT 2014

The impact of Toll-like-receptor-9 on intestinal microbiota composition and extra-intestinal sequelae in experimental Toxoplasma gondii induced ileitis.

Gut pathogens

Bereswill S,Kühl AA,Alutis M,Fischer A,Möhle L,Struck D,Liesenfeld O,Göbel UB,Dunay IR,Heimesaat MM

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Mon Jun 16 00:00:00 EDT 2014

VEGFR-1 blockade disrupts peri-implantation decidual angiogenesis and macrophage recruitment.

Vascular cell

Douglas NC,Zimmermann RC,Tan QK,Sullivan-Pyke CS,Sauer MV,Kitajewski JK,Shawber CJ

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Thu Aug 07 00:00:00 EDT 2014

VEGFR-1 blockade disrupts peri-implantation decidual angiogenesis and macrophage recruitment.

Vascular cell

Douglas NC,Zimmermann RC,Tan QK,Sullivan-Pyke CS,Sauer MV,Kitajewski JK,Shawber CJ

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunocytochemistry

Thu Aug 07 00:00:00 EDT 2014

Genetic ablation of epidermal EGFR reveals the dynamic origin of adverse effects of anti-EGFR therapy.

Science translational medicine

Mascia F,Lam G,Keith C,Garber C,Steinberg SM,Kohn E,Yuspa SH

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Wed Aug 21 00:00:00 EDT 2013

Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis.

PloS one

Harmel-Laws E,Mann EA,Cohen MB,Steinbrecher KA

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Mon Aug 18 00:00:00 EDT 2014

Survey of extra-intestinal immune responses in asymptomatic long-term Campylobacter jejuni-infected mice.

European journal of microbiology & immunology

Heimesaat MM,Haag LM,Fischer A,Otto B,Kühl AA,Göbel UB,Bereswill S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Sun Sep 01 00:00:00 EDT 2013

Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms.

The American journal of pathology

Ninković J,Roy S

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Thu Mar 01 00:00:00 EST 2012

DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity.

Journal of immunology (Baltimore, Md. : 1950)

Guerriero JL,Ditsworth D,Catanzaro JM,Sabino G,Furie MB,Kew RR,Crawford HC,Zong WX

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Flow Cytometry

Tue Mar 15 00:00:00 EDT 2011

Selective gelatinase blockage ameliorates acute DSS colitis.

European journal of microbiology & immunology

Heimesaat MM,Dunay IR,Fuchs D,Trautmann D,Fischer A,Kühl AA,Loddenkemper C,Batra A,Siegmund B,Krell HW,Bereswill S,Liesenfeld O

Published figure using F4/80 monoclonal antibody (Product # 67-4801-82) in Immunohistochemistry

Thu Sep 01 00:00:00 EDT 2011

Bioinformatics

Protein Aliases: Adhesion G protein-coupled receptor E1; Cell surface glycoprotein F4/80; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; lymphocyte antigen 71

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Gene Aliases: Adgre1; DD7A5-7; EGF-TM7; Emr1; F4/80; Gpf480; Ly71; TM7LN3

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UniProt ID: (Mouse) Q61549

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Entrez Gene ID: (Mouse) 13733

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Function(s)

signal transducer activity transmembrane signaling receptor activity G-protein coupled receptor activity calcium ion binding G-protein coupled receptor

Process(es)

signal transduction cell surface receptor signaling pathway G-protein coupled receptor signaling pathway

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F4/80 Monoclonal Antibody (BM8), Super Bright™ 702, eBioscience™

F4/80 Antibody (67-4801-82) in Flow

Product Details

67-4801-82

Immunohistochemistry (IHC)

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