Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MAELQMLLE EEIPGGRRAL FDSYTNLERV ADYCENNYIQ SADKQRALEE TKAYTTQSLA SVAYLINTLA NNVLQMLDIQ ASQLRRMESS INHISQTVDI HKEKVARREI GILTTNKNTS RTHKIIAPAN LERPVRYIRK PIDYTILDDI GHGVKVSTQN MKMGGLPRTT PPTQKPPSPP MSGKGTLGRH SPYRTLEPVR PPVVPNDYVP SPTRNMAPSQ QSPVRTASVN QRNRTYSSSG SSGGSHPSSR SSSRENSGSG SVGVPIAVPT PSPPSV (1-275 aa encoded by B C001439)
ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Abelson interactor 2; Abi-2; abl binding protein 3; Abl interactor 2; Abl-binding protein 3; abl-interacting protein 1 (SH3-containing protein); abl-interactor protein 2b; AblBP3; arg protein tyrosine kinase-binding protein; Arg-binding protein 1; ArgBP1; thyroid hormone responsive protein
Gene Aliases: 8430425M24Rik; ABI-2; ABI2; ABI2B; AblBP3; AI839867; AIP-1; argBP1; ARGBPIA; argBPIB; C130078H13; SSH3BP2
UniProt ID: (Human) Q9NYB9, (Mouse) P62484
Entrez Gene ID: (Human) 10152, (Mouse) 329165, (Rat) 286928
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