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Product Details
H00010152-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ABI2 (NP_005750.4, 1 a.a. approximately 475 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAELQMLLEE EIPGGRRALF DSYTNLERVA DYCENNYIQS ADKQRALEET KAYTTQSLAS VAYLINTLAN NVLQMLDIQA SQLRRMESSI NHISQTVDIH KEKVARREIG ILTTNKNTSR THKIIAPANL ERPVRYIRKP IDYTILDDIG HGVKVSTQNM KMGGLPRTTP PTQKPPSPPM SGKGTLGRHS PYRTLEPVRP PVVPNDYVPS PTRNMAPSQQ SPVRTASVNQ RNRTYSSSGS SGGSHPSSRS SSRENSGSGS VGVPIAVPTP SPPSVFPGHP VQFYSMNRPA SRHTPPTIGG SLPYRRPPSI TSQTSLQNQM NGGPFYSQNP VSLAPPPPSI LQVTPQLPLM GFVARVQENI SDTPPPPPPV EEPVFDESPP PPPPPEDYEE EEAAVVEYSD PYAEEDPPWA PRSYLEKVVA IYDYTKDKED ELSFQEGAII YVIKKNDDGW YEGVMNGVTG LFPGNYVESI MHYSE
Target Information
ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Abelson interactor 2; Abi-2; abl binding protein 3; Abl interactor 2; Abl-binding protein 3; abl-interacting protein 1 (SH3-containing protein); abl-interactor protein 2b; AblBP3; arg protein tyrosine kinase-binding protein; Arg-binding protein 1; ArgBP1
Gene Aliases: ABI-2; ABI2; ABI2B; AblBP3; AIP-1; argBP1; ARGBPIA; argBPIB; SSH3BP2
UniProt ID: (Human) Q9NYB9
Entrez Gene ID: (Human) 10152
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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