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The antibody detects endogenous levels of total ADAMTSL1 protein.
Punctin (ADAMTSL-1) is a secreted molecule, expressed in adult skeletal muscle, resembling members of the ADAMTS family of proteases, containing four thrombospondin type I repeats. Human punctin cleaves aggrecan and is thereby classified as an aggrecanase. Like the ADAMTS proteases, each domain in punctin has an even number of cysteine residues suggesting that each domain may have internal disulfide bonds and that punctin consists of a series of independently folded and disulfide-bonded domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a disintegrin and metalloproteinase; ADAM; ADAM-TS related protein 1; ADAMs; ADAMTS-like 1; ADAMTS-like protein 1; ADAMTSL-1; DKFZp686L03130; FLJ35283; FLJ41032; FLJ46891; metalloendopeptidases; MGC118803; MGC118805; MGC40193; Punctin-1; RP11-220B22.2
Gene Aliases: ADAMTSL-1; ADAMTSL1; ADAMTSR1; C9orf94; PUNCTIN; UNQ528/PRO1071
UniProt ID: (Human) Q8N6G6
Entrez Gene ID: (Human) 92949
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