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Punctin (ADAMTSL-1) is a secreted molecule, expressed in adult skeletal muscle, resembling members of the ADAMTS family of proteases, containing four thrombospondin type I repeats. Human punctin cleaves aggrecan and is thereby classified as an aggrecanase. Like the ADAMTS proteases, each domain in punctin has an even number of cysteine residues suggesting that each domain may have internal disulfide bonds and that punctin consists of a series of independently folded and disulfide-bonded domains.
5930437A14Rik; 6720426B09Rik; a disintegrin and metalloproteinase; ADAM; ADAMs; ADAMTS like 1; ADAM-TS related protein 1; Adamtsl1; ADAMTSL-1; ADAMTS-like 1; ADAMTS-like protein 1; ADAMTSR1; C9orf94; DKFZp686L03130; FLJ35283; FLJ41032; FLJ46891; metalloendopeptidases; MGC118803; MGC118805; MGC40193; PUNCTIN; Punctin-1; RP11-220B22.2; UNQ528/PRO1071
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