Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: SLVIQDYWWS VDRLATCSAS CGNRGVQQPR LRCLLNSTEV NPAHCAGKVR PAVQPIACNR RDCPSRWMVT SWSACTRSCG GGVQTRRVTC QKLKASGIST PVSNDMCTQV AKRPVDTQAC NQQLCVEWAF SSWGQCNGPC IGPHLAVQHR QVFCQTRDGI TLPSEQCSAL PRPVSTQNCW SEACSVHWRV SLWTLCTATC GNYGFQSRRV ECVHARTNKA VPEHLCSWGP RPANWQRCNI TPCENMECRD TTRYCEKVKQ LKLCQLSQFK SRCCGTCGKA; Positive Samples: U-87MG, A-375, HeLa, Mouse heart, Mouse spleen, Rat heart; Cellular Location: extracellular matrix, extracellular space
Punctin (ADAMTSL-1) is a secreted molecule, expressed in adult skeletal muscle, resembling members of the ADAMTS family of proteases, containing four thrombospondin type I repeats. Human punctin cleaves aggrecan and is thereby classified as an aggrecanase. Like the ADAMTS proteases, each domain in punctin has an even number of cysteine residues suggesting that each domain may have internal disulfide bonds and that punctin consists of a series of independently folded and disulfide-bonded domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a disintegrin and metalloproteinase; ADAM; ADAM-TS related protein 1; ADAMs; ADAMTS-like 1; ADAMTS-like protein 1; ADAMTSL-1; DKFZp686L03130; FLJ35283; FLJ41032; FLJ46891; metalloendopeptidases; MGC118803; MGC118805; MGC40193; Punctin-1; RP11-220B22.2
Gene Aliases: 5930437A14Rik; 6720426B09Rik; ADAMTSL-1; ADAMTSL1; ADAMTSR1; C9orf94; PUNCTIN; UNQ528/PRO1071
UniProt ID: (Human) Q8N6G6, (Mouse) Q8BLI0
Entrez Gene ID: (Human) 92949, (Mouse) 77739, (Rat) 362539
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