Product References
Calcineurin Aα Contributes to IgE-Dependent Mast-Cell Mediator Secretion in Allergic Inflammation.
Journal of innate immunity
Leong E,Pang Z,Stadnyk AW,Lin TJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Jul 07 00:00:00 EDT 2022
Gastruloids as in vitro models of embryonic blood development with spatial and temporal resolution.
Scientific reports
Rossi G,Giger S,Hübscher T,Lutolf MP
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Aug 04 00:00:00 EDT 2022
Specific overexpression of SIRT1 in mesenchymal stem cells rescues hematopoiesis niche in BMI1 knockout mice through promoting CXCL12 expression.
International journal of biological sciences
Li J,Li X,Sun W,Zhang J,Yan Q,Wu J,Jin J,Lu R,Miao D
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Apr 15 00:00:00 EDT 2022
Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis.
Nature communications
Zhao M,Shao F,Yu D,Zhang J,Liu Z,Ma J,Xia P,Wang S
25-1171-82 was used in Flow cytometry/Cell sorting to show that ILC2s undergo translocation via the lung-gut axis upon IL-33 treatment.
Fri Dec 09 00:00:00 EST 2022
Preventive Effects of a Human Hematopoietic Mesenchymal Stem Cell (hHMSC) Therapy in Ovalbumin-Induced Food Allergy.
Biomedicines
Lee DG,Lee YJ,Park SH,Park HR,Kang H,Kim JE
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon Feb 21 00:00:00 EST 2022
Inaccessible LCG Promoters Act as Safeguards to Restrict T Cell Development to Appropriate Notch Signaling Environments.
Stem cell reports
Furuyama S,Wu QV,Varnum-Finney B,Sandstrom R,Meuleman W,Stamatoyannopoulos JA,Bernstein ID
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Tue Apr 13 00:00:00 EDT 2021
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
25-1171-82 was used in Flow Cytometry to show that IL-22, a cytokine produced by RORγt+ lymphocytes inhibits IL-13-induced tuft cell differentiation in vitro, and suppresses the tuft cell-type 2 immune circuit and small intestine lengthening in vivo, highlighting its key role in gut tissue remodeling.
Thu Jul 22 00:00:00 EDT 2021
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
25-1171-82 was used in Flow Cytometry to show that IL-22, a cytokine produced by RORγt+ lymphocytes inhibits IL-13-induced tuft cell differentiation in vitro, and suppresses the tuft cell-type 2 immune circuit and small intestine lengthening in vivo, highlighting its key role in gut tissue remodeling.
Thu Jul 22 00:00:00 EDT 2021
SNAP23 is essential for platelet and mast cell development and required in connective tissue mast cells for anaphylaxis.
The Journal of biological chemistry
Cardenas RA,Gonzalez R,Sanchez E,Ramos MA,Cardenas EI,Rodarte AI,Alcazar-Felix RJ,Isaza A,Burns AR,Heidelberger R,Adachi R
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon Aug 02 00:00:00 EDT 2021
mMCP7, a Mouse Ortholog of δ Tryptase, Mediates Pelvic Tactile Allodynia in a Model of Chronic Pelvic Pain.
Frontiers in pain research (Lausanne, Switzerland)
Pattabiraman G,Liu Z,Paul M,Schaeffer AJ,Thumbikat P
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Oct 20 00:00:00 EDT 2023
Analysis of Radiation-Induced Changes in Cell Cycle and DNA Damage of Murine Hematopoietic Stem Cells by Multi-Color Flow Cytometry.
Current protocols
Majumdar D,Pietras EM,Pawar SA
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
The essential roles of Mps1 in spermatogenesis and fertility in mice.
Cell death & disease
Fang Q,Chen XL,Zhang L,Li YB,Sun TZ,Yang CX,Chang JF,Yang XM,Sun F
25-1171-82 was used in Immunocytochemistry to elucidate the role of monopolar spindle 1 in spermatogenesis using mice models.
Mon May 24 00:00:00 EDT 2021
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia.
Cell stem cell
Shen C,Sheng Y,Zhu AC,Robinson S,Jiang X,Dong L,Chen H,Su R,Yin Z,Li W,Deng X,Chen Y,Hu YC,Weng H,Huang H,Prince E,Cogle CR,Sun M,Zhang B,Chen CW,Marcucci G,He C,Qian Z,Chen J
25-1171-82 was used in Flow Cytometry to reveal crucial functions of ALKBH5 in leukemogenesis and LSC/LIC self-renewal/maintenance and highlight the therapeutic potential of targeting the ALKBH5/m6A axis.
Thu Jul 02 00:00:00 EDT 2020
Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development.
Developmental cell
Dege C,Fegan KH,Creamer JP,Berrien-Elliott MM,Luff SA,Kim D,Wagner JA,Kingsley PD,McGrath KE,Fehniger TA,Palis J,Sturgeon CM
25-1171 was used in Flow cytometry/Cell sorting to identify an extra-embryonic origin of potently cytotoxic NK cells, suggesting that ontogenic origin is a relevant factor in designing hPSC-derived adoptive immunotherapies.
Mon Apr 20 00:00:00 EDT 2020
The aging skin microenvironment dictates stem cell behavior.
Proceedings of the National Academy of Sciences of the United States of America
Ge Y,Miao Y,Gur-Cohen S,Gomez N,Yang H,Nikolova M,Polak L,Hu Y,Verma A,Elemento O,Krueger JG,Fuchs E
25-1171 was used in Flow cytometry/Cell sorting to highlight the importance of SC:niche interactions and favor a model where youthfulness of the niche microenvironment plays a dominant role in dictating the properties of its SCs and tissue health and fitness.
Tue Mar 10 00:00:00 EDT 2020
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
Cell communication and signaling : CCS
Zheng Y,Wang N,Wang S,Yang B,Situ H,Zhong L,Lin Y,Wang Z
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Mar 26 00:00:00 EDT 2020
USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells.
Cell reports
van den Berk P,Lancini C,Company C,Serresi M,Sanchez-Bailon MP,Hulsman D,Pritchard C,Song JY,Schmitt MJ,Tanger E,Popp O,Mertins P,Huijbers IJ,Jacobs H,van Lohuizen M,Gargiulo G,Citterio E
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Tue Dec 29 00:00:00 EST 2020
Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System.
Biomedicines
Hong Y,Singh N,Bamopoulos S,Gjerga E,Schmalbrock LK,Balabanian K,Schick M,Keller U,Wirth M
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Wed Dec 09 00:00:00 EST 2020
TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing.
Nature communications
Schöpp T,Zoch A,Berrens RV,Auchynnikava T,Kabayama Y,Vasiliauskaitė L,Rappsilber J,Allshire RC,O'Carroll D
25-1171-82 was used in Flow Cytometry to show that TEX15 is an essential executor of mammalian PIWI-interacting RNA-directed DNA methylation.
Mon Jul 27 00:00:00 EDT 2020
Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS.
Journal of neuroinflammation
Hohsfield LA,Najafi AR,Ghorbanian Y,Soni N,Hingco EE,Kim SJ,Jue AD,Swarup V,Inlay MA,Green KN
25-1171 was used in Flow Cytometry to characterize the role and complexity of myeloid cells in the regulation of CNS cells and functional outcomes in the brain.
Sun Sep 20 00:00:00 EDT 2020
Type I Interferon α/β Receptor-Mediated Signaling Negatively Regulates Antiviral Cytokine Responses in Murine Bone-Marrow-Derived Mast Cells and Protects the Cells from Virus-Induced Cell Death.
International journal of molecular sciences
Darzianiazizi M,Mehrani Y,Chan L,Mould RC,Kulkarni RR,Sharif S,Bridle BW,Karimi K
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Nov 27 00:00:00 EST 2020
Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis.
Nature communications
Morales Torres C,Wu MY,Hobor S,Wainwright EN,Martin MJ,Patel H,Grey W,Grönroos E,Howell S,Carvalho J,Snijders AP,Bustin M,Bonnet D,Smith PD,Swanton C,Howell M,Scaffidi P
25-1171-82 was used in Flow Cytometry to investigate histone H1.0's role in mediating Quisinostat's antitumor activity.
Tue Apr 14 00:00:00 EDT 2020
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.
Cancer cell
Baccelli I,Gareau Y,Lehnertz B,Gingras S,Spinella JF,Corneau S,Mayotte N,Girard S,Frechette M,Blouin-Chagnon V,Leveillé K,Boivin I,MacRae T,Krosl J,Thiollier C,Lavallée VP,Kanshin E,Bertomeu T,Coulombe-Huntington J,St-Denis C,Bordeleau ME,Boucher G,Roux PP,Lemieux S,Tyers M,Thibault P,Hébert J,Marinier A,Sauvageau G
25-1171 was used in Flow cytometry/Cell sorting to identify an ETC complex I inhibitor and reveals the genetic landscape of OXPHOS dependency in AML.
Mon Jul 08 00:00:00 EDT 2019
Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging.
Cell stem cell
Ho YH,Del Toro R,Rivera-Torres J,Rak J,Korn C,García-García A,Macías D,González-Gómez C,Del Monte A,Wittner M,Waller AK,Foster HR,López-Otín C,Johnson RS,Nerlov C,Ghevaert C,Vainchenker W,Louache F,Andrés V,Méndez-Ferrer S
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Sep 05 00:00:00 EDT 2019
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment.
Cell stem cell
Yamamoto R,Wilkinson AC,Ooehara J,Lan X,Lai CY,Nakauchi Y,Pritchard JK,Nakauchi H
25-1171 was used in Flow cytometry/Cell sorting to determine the age-related functional changes to the haematopoietic stem cell compartment.
Thu Apr 05 00:00:00 EDT 2018
Defective germline reprogramming rewires the spermatogonial transcriptome.
Nature structural & molecular biology
Vasiliauskaitė L,Berrens RV,Ivanova I,Carrieri C,Reik W,Enright AJ,O'Carroll D
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias.
Genes & development
Kim SK,Knight DA,Jones LR,Vervoort S,Ng AP,Seymour JF,Bradner JE,Waibel M,Kats L,Johnstone RW
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling.
Nature communications
Lam J,van den Bosch M,Wegrzyn J,Parker J,Ibrahim R,Slowski K,Chang L,Martinez-Høyer S,Condorelli G,Boldin M,Deng Y,Umlandt P,Fuller M,Karsan A
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Wed Jun 20 00:00:00 EDT 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Tue Nov 20 00:00:00 EST 2018
The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.
eLife
Schmidt K,Zhang Q,Tasdogan A,Petzold A,Dahl A,Arneth BM,Slany R,Fehling HJ,Kranz A,Stewart AF,Anastassiadis K
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation.
Stem cell reports
Hamanaka S,Umino A,Sato H,Hayama T,Yanagida A,Mizuno N,Kobayashi T,Kasai M,Suchy FP,Yamazaki S,Masaki H,Yamaguchi T,Nakauchi H
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Tue Oct 09 00:00:00 EDT 2018
Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis.
eLife
Bergiers I,Andrews T,Vargel Bölükbaşı Ö,Buness A,Janosz E,Lopez-Anguita N,Ganter K,Kosim K,Celen C,Itır Perçin G,Collier P,Baying B,Benes V,Hemberg M,Lancrin C
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Tue Mar 20 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-Mediated Mast Cell Activation, Independent of the Transmembrane Adaptor PAG/CSK-Binding Protein.
Frontiers in immunology
Potuckova L,Draberova L,Halova I,Paulenda T,Draber P
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon Oct 07 00:00:00 EDT 2019
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
25-1171 was used in Flow cytometry/Cell sorting to characterise the expression signature that distinguishes arterial endothelial cells from sinusoidal endothelial cells.
Fri Jun 22 00:00:00 EDT 2018
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Nature
Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Apr 06 00:00:00 EDT 2017
Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation.
Cell
Wang S,Xia P,Chen Y,Qu Y,Xiong Z,Ye B,Du Y,Tian Y,Yin Z,Xu Z,Fan Z
25-1171 was used in Flow cytometry/Cell sorting to identify a regulatory subpopulation of innate lymphoid cells that exists in the gut, and harbour a unique gene identity.
Thu Sep 21 00:00:00 EDT 2017
Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.
Cell
Ge Y,Gomez NC,Adam RC,Nikolova M,Yang H,Verma A,Lu CP,Polak L,Yuan S,Elemento O,Fuchs E
25-1171 was used in Flow cytometry/Cell sorting to investigate the homeostatic mechanisms of tissue regeneration and wound repair by tissue stem cells in the skin, that can be hijacked by cancer cells.
Thu May 04 00:00:00 EDT 2017
Differential cytokine contributions of perivascular haematopoietic stem cell niches.
Nature cell biology
Asada N,Kunisaki Y,Pierce H,Wang Z,Fernandez NF,Birbrair A,Ma'ayan A,Frenette PS
25-1171 was used in Flow cytometry/Cell sorting to demonstrate that the effects of cytokines regulating haematopoietic stem cell functions are dependent on the producing cell sources.
Wed Mar 01 00:00:00 EST 2017
AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis.
Circulation research
Abdel Malik R,Zippel N,Frömel T,Heidler J,Zukunft S,Walzog B,Ansari N,Pampaloni F,Wingert S,Rieger MA,Wittig I,Fisslthaler B,Fleming I
25-1171 was used in Flow cytometry/Cell sorting to elucidate the role of the AMPKa2 catalytic subunit in vascular repair following ischemia.
Fri Jan 06 00:00:00 EST 2017
A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming.
Nature structural & molecular biology
Vasiliauskaitė L,Vitsios D,Berrens RV,Carrieri C,Reik W,Enright AJ,O'Carroll D
25-1171 was used in Flow cytometry/Cell sorting to demonstrate a PIWI-interacting RNA biogenesis pathway that sustains partial MIWI2 function and reprogramming activity in the absence of MILI.
Sat Jul 01 00:00:00 EDT 2017
Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.
The EMBO journal
Kawasaki T,Ito K,Miyata H,Akira S,Kawai T
25-1171 was used in Flow cytometry/Cell sorting to examine the role of a phosphoinositide kinase PIKfyve in alveolar macrophage development and function.
Wed Jun 14 00:00:00 EDT 2017
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Developmental cell
Hewitt KJ,Katsumura KR,Matson DR,Devadas P,Tanimura N,Hebert AS,Coon JJ,Kim JS,Dewey CN,Keles S,Hao S,Paulson RF,Bresnick EH
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon Aug 07 00:00:00 EDT 2017
Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model.
Scientific reports
Alzubi J,Pallant C,Mussolino C,Howe SJ,Thrasher AJ,Cathomen T
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Sep 29 00:00:00 EDT 2017
Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome.
Nature communications
Douam F,Hrebikova G,Albrecht YE,Sellau J,Sharon Y,Ding Q,Ploss A
25-1171 was used in Flow cytometry/Cell sorting to demonstrate the tracking of and sense viral RNA at single-cell resolution within complex subsets of the human and murine immune system in different mouse models.
Tue Mar 14 00:00:00 EDT 2017
Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.
Stem cell reports
Redgrave RE,Tual-Chalot S,Davison BJ,Singh E,Hall D,Amirrasouli MM,Gilchrist D,Medvinsky A,Arthur HM
25-1171 was used in Flow cytometry/Cell sorting to demonstrate that the pro-angiogenic properties of the cardiosphere-derived-cell secretome are endoglin dependent.
Tue May 09 00:00:00 EDT 2017
Mouse Label-Retaining Cells Are Molecularly and Functionally Distinct From Reserve Intestinal Stem Cells.
Gastroenterology
Li N,Nakauka-Ddamba A,Tobias J,Jensen ST,Lengner CJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2016
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.
Nature cell biology
Pietras EM,Mirantes-Barbeito C,Fong S,Loeffler D,Kovtonyuk LV,Zhang S,Lakshminarasimhan R,Chin CP,Techner JM,Will B,Nerlov C,Steidl U,Manz MG,Schroeder T,Passegué E
25-1171 was used in Flow cytometry/Cell sorting to identify a critical regulatory circuit that tailors HSC responses to acute needs, and is likely to underlie deregulated blood homeostasis in chronic inflammation conditions.
Wed Jun 01 00:00:00 EDT 2016
Strand-specific in vivo screen of cancer-associated miRNAs unveils a role for miR-21(∗) in SCC progression.
Nature cell biology
Ge Y,Zhang L,Nikolova M,Reva B,Fuchs E
25-1171 was used in Flow cytometry/Cell sorting to identify which of the microRNAs abundantly expressed in squamous cell carcinoma are key drivers in malignant progression.
Fri Jan 01 00:00:00 EST 2016
Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis.
The Journal of clinical investigation
Gu H,Chen C,Hao X,Wang C,Zhang X,Li Z,Shao H,Zeng H,Yu Z,Xie L,Xia F,Zhang F,Liu X,Zhang Y,Jiang H,Zhu J,Wan J,Wang C,Weng W,Xie J,Tao M,Zhang CC,Liu J,Chen GQ,Zheng J
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Physiological and hypoxic oxygen concentration differentially regulates human c-Kit+ cardiac stem cell proliferation and migration.
American journal of physiology. Heart and circulatory physiology
Bellio MA,Rodrigues CO,Landin AM,Hatzistergos KE,Kuznetsov J,Florea V,Valasaki K,Khan A,Hare JM,Schulman IH
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2016
Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr.
Molecular and cellular biology
Thoms JA,Knezevic K,Liu JJ,Glaros EN,Thai T,Qiao Q,Campbell H,Packham D,Huang Y,Papathanasiou P,Tunningley R,Whittle B,Yeung AW,Chandrakanthan V,Hesson L,Chen V,Wong JW,Purton LE,Ward RL,Thomas SR,Pimanda JE
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2016
New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.
Molecular and cellular biology
Bambouskova M,Polakovicova I,Halova I,Goel G,Draberova L,Bugajev V,Doan A,Utekal P,Gardet A,Xavier RJ,Draber P
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2016
The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1.
Leukemia research
Mian YA,Zeleznik-Le NJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Heterogeneity in readouts of canonical wnt pathway activity within intestinal crypts.
Developmental dynamics : an official publication of the American Association of Anatomists
Li N,Yousefi M,Nakauka-Ddamba A,Tobias JW,Jensen ST,Morrisey EE,Lengner CJ
25-1171 was used in Flow cytometry/Cell sorting to describe a novel Axin2-CreERT2-tdTomato allele that efficiently marks both Wnt(High) crypt base columnar stem cells and radioresistant reserve intestinal stem cells.
Mon Aug 01 00:00:00 EDT 2016
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Sun May 15 00:00:00 EDT 2016
BMP and Hedgehog Regulate Distinct AGM Hematopoietic Stem Cells Ex Vivo.
Stem cell reports
Crisan M,Solaimani Kartalaei P,Neagu A,Karkanpouna S,Yamada-Inagawa T,Purini C,Vink CS,van der Linden R,van Ijcken W,Chuva de Sousa Lopes SM,Monteiro R,Mummery C,Dzierzak E
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Tue Mar 08 00:00:00 EST 2016
LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration.
Nature communications
Shi Y,Wu W,Chai Q,Li Q,Hou Y,Xia H,Ren B,Xu H,Guo X,Jin C,Lv M,Wang Z,Fu YX,Zhu M
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Aug 05 00:00:00 EDT 2016
Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity.
PloS one
Jonas BA,Johnson C,Gratzinger D,Majeti R
25-1171 was used in Flow cytometry/Cell sorting to report several new t-AML/MDS mouse models that could potentially be used to further define disease pathogenesis and test novel therapeutics.
Wed Jul 26 00:00:00 EDT 2017
Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal.
Nature
Acar M,Kocherlakota KS,Murphy MM,Peyer JG,Oguro H,Inra CN,Jaiyeola C,Zhao Z,Luby-Phelps K,Morrison SJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2015
Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.
Nature immunology
Grajales-Reyes GE,Iwata A,Albring J,Wu X,Tussiwand R,Kc W,Kretzer NM,Briseño CG,Durai V,Bagadia P,Haldar M,Schönheit J,Rosenbauer F,Murphy TL,Murphy KM
25-1171 was used in Flow cytometry/Cell sorting to investigate the role of the transcription factors Batf3 and IRF8 in the development of CD8α(+) conventional dendritic cells (cDCs)..
Wed Jul 01 00:00:00 EDT 2015
Mast cells mediate malignant pleural effusion formation.
The Journal of clinical investigation
Giannou AD,Marazioti A,Spella M,Kanellakis NI,Apostolopoulou H,Psallidas I,Prijovich ZM,Vreka M,Zazara DE,Lilis I,Papaleonidopoulos V,Kairi CA,Patmanidi AL,Giopanou I,Spiropoulou N,Harokopos V,Aidinis V,Spyratos D,Teliousi S,Papadaki H,Taraviras S,Snyder LA,Eickelberg O,Kardamakis D,Iwakura Y,Feyerabend TB,Rodewald HR,Kalomenidis I,Blackwell TS,Agalioti T,Stathopoulos GT
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Inhibition of the CXCL12/CXCR4 chemokine axis with AMD3100, a CXCR4 small molecule inhibitor, worsens murine hepatic injury.
Hepatology research : the official journal of the Japan Society of Hepatology
Saiman Y,Jiao J,Fiel MI,Friedman SL,Aloman C,Bansal MB
25-1171 was used in Flow cytometry/Cell sorting to suggest that inhibition of the CXCR4/CXCL12 chemokine axis is injurious through modulation of the hepatic inflammatory response.
Wed Jul 01 00:00:00 EDT 2015
Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation.
PloS one
Zoch A,Mayerl S,Schulz A,Greither T,Frappart L,Rübsam J,Heuer H,Giovannini M,Morrison H
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon May 23 00:00:00 EDT 2016
Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.
Nature communications
Balasubramani A,Larjo A,Bassein JA,Chang X,Hastie RB,Togher SM,Lähdesmäki H,Rao A
25-1171 was used in Flow cytometry/Cell sorting to demonstrate that ASXL1 truncations confer enhanced activity on the ASXL1-BAP1 complex.
Mon Jun 22 00:00:00 EDT 2015
Mast Cells Participate in Corneal Development in Mice.
Scientific reports
Liu J,Fu T,Song F,Xue Y,Xia C,Liu P,Wang H,Zhong J,Li Q,Chen J,Li Y,Cai D,Li Z
25-1171 was used in Flow cytometry/Cell sorting to examine the distribution of mast cells in the mouse cornea and the mechanisms that control their migration.
Wed Dec 02 00:00:00 EST 2015
Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.
Nature medicine
Bruns I,Lucas D,Pinho S,Ahmed J,Lambert MP,Kunisaki Y,Scheiermann C,Schiff L,Poncz M,Bergman A,Frenette PS
25-1171 was used in Flow cytometry/Cell sorting to indicate that a terminally differentiated cell type derived from HSCs contributes to the HSC niche, directly regulating HSC behavior.
Sat Nov 01 00:00:00 EDT 2014
The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.
Nature immunology
Agudo J,Ruzo A,Tung N,Salmon H,Leboeuf M,Hashimoto D,Becker C,Garrett-Sinha LA,Baccarini A,Merad M,Brown BD
25-1171 was used in Flow cytometry/Cell sorting to identify the miR-126-VEGFR2 axis as an important regulator of the innate response that operates through multiscale control of pDCs.
Wed Jan 01 00:00:00 EST 2014
Abi3bp regulates cardiac progenitor cell proliferation and differentiation.
Circulation research
Hodgkinson CP,Gomez JA,Payne AJ,Zhang L,Wang X,Dal-Pra S,Pratt RE,Dzau VJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Dec 05 00:00:00 EST 2014
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
Smurf2 regulates hematopoietic stem cell self-renewal and aging.
Aging cell
Ramkumar C,Kong Y,Trabucco SE,Gerstein RM,Zhang H
25-1171 was used in Flow cytometry/Cell sorting to suggest that Smurf2 plays an important role in regulating HSC self-renewal and ageing.
Sun Jun 01 00:00:00 EDT 2014
Pharmacological mobilization of endogenous stem cells significantly promotes skin regeneration after full-thickness excision: the synergistic activity of AMD3100 and tacrolimus.
The Journal of investigative dermatology
Lin Q,Wesson RN,Maeda H,Wang Y,Cui Z,Liu JO,Cameron AM,Gao B,Montgomery RA,Williams GM,Sun Z
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon Sep 01 00:00:00 EDT 2014
A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.
Development (Cambridge, England)
Gilmour J,Assi SA,Jaegle U,Kulu D,van de Werken H,Clarke D,Westhead DR,Philipsen S,Bonifer C
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Sun Jun 01 00:00:00 EDT 2014
CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections.
European journal of immunology
Bakocevic N,Claser C,Yoshikawa S,Jones LA,Chew S,Goh CC,Malleret B,Larbi A,Ginhoux F,de Lafaille MC,Karasuyama H,Renia L,Ng LG
25-1171 was used in Flow cytometry/Cell sorting to study the CD41 expression within basophils from the blood during both steady state and malarial inections within mice.
Sun Jun 01 00:00:00 EDT 2014
Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Jiao J,Dragomir AC,Kocabayoglu P,Rahman AH,Chow A,Hashimoto D,Leboeuf M,Kraus T,Moran T,Carrasco-Avino G,Friedman SL,Merad M,Aloman C
25-1171 was used in Flow cytometry/Cell sorting to investigate the role of dendritic cells in neutrophil homeostasis, showing a central role in regulation of bone marrow release and survival of neutrophils.
Tue Apr 01 00:00:00 EDT 2014
Identification of hematopoietic-specific regulatory elements from the CD45 gene and use for lentiviral tracking of transplanted cells.
Experimental hematology
Duong KL,Das S,Yu S,Barr JY,Jena S,Kim E,Zavazava N,Colgan JD,Xue HH,Levasseur DN
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon Sep 01 00:00:00 EDT 2014
F-box protein FBXL16 binds PP2A-B55α and regulates differentiation of embryonic stem cells along the FLK1+ lineage.
Molecular & cellular proteomics : MCP
Honarpour N,Rose CM,Brumbaugh J,Anderson J,Graham RL,Sweredoski MJ,Hess S,Coon JJ,Deshaies RJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Sat Mar 01 00:00:00 EST 2014
Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.
The Journal of biological chemistry
Ito K,Yamazaki S,Yamamoto R,Tajima Y,Yanagida A,Kobayashi T,Kato-Itoh M,Kakuta S,Iwakura Y,Nakauchi H,Kamiya A
25-1171 was used in Flow cytometry/Cell sorting to investigate the precise role and expression pattern of brain-expressed X-linked genes in endocrine and tissue stem/progenitor cells in mice.
Fri Oct 24 00:00:00 EDT 2014
Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.
Nature medicine
Lucas D,Scheiermann C,Chow A,Kunisaki Y,Bruns I,Barrick C,Tessarollo L,Frenette PS
25-1171 was used in Flow cytometry/Cell sorting to demonstrate the potential benefit of adrenergic nerve protection for shielding hematopoietic niches from injury.
Sat Jun 01 00:00:00 EDT 2013
Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration.
Nature medicine
Lucas D,Scheiermann C,Chow A,Kunisaki Y,Bruns I,Barrick C,Tessarollo L,Frenette PS
25-1171 was used in Flow cytometry/Cell sorting to demonstrate the potential benefit of adrenergic nerve protection for shielding hematopoietic niches from injury.
Sat Jun 01 00:00:00 EDT 2013
Arteriolar niches maintain haematopoietic stem cell quiescence.
Nature
Kunisaki Y,Bruns I,Scheiermann C,Ahmed J,Pinho S,Zhang D,Mizoguchi T,Wei Q,Lucas D,Ito K,Mar JC,Bergman A,Frenette PS
25-1171 was used in Flow cytometry/Cell sorting to investigate the spatial localisation of quiescent haematopoietic stem cells in bone marrow, showing that arteriolar niches maintain quiescence.
Thu Oct 31 00:00:00 EDT 2013
miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.
Nature cell biology
Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Mar 01 00:00:00 EST 2013
CCX-CKR deficiency alters thymic stroma impairing thymocyte development and promoting autoimmunity.
Blood
Bunting MD,Comerford I,Seach N,Hammett MV,Asquith DL,Körner H,Boyd RL,Nibbs RJ,McColl SR
25-1171 was used in Flow cytometry/Cell sorting to identify a novel role for CCX-CKR in regulating cTEC biology.
Thu Jan 03 00:00:00 EST 2013
CX(3)CR1(+) macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium.
Mucosal immunology
Manta C,Heupel E,Radulovic K,Rossini V,Garbi N,Riedel CU,Niess JH
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo.
PloS one
Wu X,Satpathy AT,Kc W,Liu P,Murphy TL,Murphy KM
25-1171 was used in Flow cytometry/Cell sorting to investigate the role of Bcl11a in the development of dendritic cells, showing that it controls Flt3 expression in early hematopoietic progenitors and is required for pDC development.
Fri Jan 10 00:00:00 EST 2014
Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation.
Nature communications
Kabata H,Moro K,Fukunaga K,Suzuki Y,Miyata J,Masaki K,Betsuyaku T,Koyasu S,Asano K
25-1171 was used in Flow cytometry/Cell sorting to investigate the role of the IL-33/NH-cell axis in corticosteroid resistance.
Thu Jun 12 00:00:00 EDT 2014
IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.
Blood
Balkhi MY,Willette-Brown J,Zhu F,Chen Z,Liu S,Guttridge DC,Karin M,Hu Y
25-1171-82 was used in Flow Cytometry to demonstrate that IKKα regulates B-lineage commitment via combined canonical and noncanonical NF-κB transcriptional activities to target Pax5 expression during hematopoiesis.
Thu Jun 07 00:00:00 EDT 2012
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion.
The EMBO journal
Gu P,Min JN,Wang Y,Huang C,Peng T,Chai W,Chang S
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Wed May 16 00:00:00 EDT 2012
Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses.
Proceedings of the National Academy of Sciences of the United States of America
Purtha WE,Swiecki M,Colonna M,Diamond MS,Bhattacharya D
25-1171 was used in Flow cytometry/Cell sorting to study the functional role of interferon regulatory factor-5 in human autoimmune disease pathogenesis.
Tue Apr 10 00:00:00 EDT 2012
Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression.
Stem cells (Dayton, Ohio)
Koyano-Nakagawa N,Kweon J,Iacovino M,Shi X,Rasmussen TL,Borges L,Zirbes KM,Li T,Perlingeiro RC,Kyba M,Garry DJ
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2012
CD11c+ cells are required for antigen-induced increase of mast cells in the lung.
Journal of immunology (Baltimore, Md. : 1950)
Dahlin JS,Feinstein R,Cui Y,Heyman B,Hallgren J
25-1171 was used in Flow cytometry/Cell sorting to determine the contribution of Ag-stimulated CD11c(+) cells to the allergic response in asthmatics.
Mon Oct 15 00:00:00 EDT 2012
Partial characterization of the Sox2+ cell population in an adult murine model of digit amputation.
Tissue engineering. Part A
Agrawal V,Siu BF,Chao H,Hirschi KK,Raborn E,Johnson SA,Tottey S,Hurley KB,Medberry CJ,Badylak SF
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Sun Jul 01 00:00:00 EDT 2012
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Nature
Zuber J,Shi J,Wang E,Rappaport AR,Herrmann H,Sison EA,Magoon D,Qi J,Blatt K,Wunderlich M,Taylor MJ,Johns C,Chicas A,Mulloy JC,Kogan SC,Brown P,Valent P,Bradner JE,Lowe SW,Vakoc CR
25-1171 was used in Flow cytometry/Cell sorting to establish small-molecule inhibition of Brd4 as a promising therapeutic strategy in acute myeloid leukaemia.
Wed Aug 03 00:00:00 EDT 2011
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Nature
Zuber J,Shi J,Wang E,Rappaport AR,Herrmann H,Sison EA,Magoon D,Qi J,Blatt K,Wunderlich M,Taylor MJ,Johns C,Chicas A,Mulloy JC,Kogan SC,Brown P,Valent P,Bradner JE,Lowe SW,Vakoc CR
25-1171 was used in Flow cytometry/Cell sorting to establish small-molecule inhibition of Brd4 as a promising therapeutic strategy in acute myeloid leukaemia.
Wed Aug 03 00:00:00 EDT 2011
Essential roles for Pot1b in HSC self-renewal and survival.
Blood
Wang Y,Shen MF,Chang S
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.
Blood
Cook BD,Liu S,Evans T
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Jun 16 00:00:00 EDT 2011
Exacerbated experimental autoimmune encephalomyelitis in mast-cell-deficient Kit W-sh/W-sh mice.
Laboratory investigation; a journal of technical methods and pathology
Piconese S,Costanza M,Musio S,Tripodo C,Poliani PL,Gri G,Burocchi A,Pittoni P,Gorzanelli A,Colombo MP,Pedotti R
25-1171 was used in Flow cytometry/Cell sorting to investigate the potential detrimental role of mast cells in experimental autoimmune encephalomyelitis.
Fri Apr 01 00:00:00 EDT 2011
Intramuscular VEGF activates an SDF1-dependent progenitor cell cascade and an SDF1-independent muscle paracrine cascade for cardiac repair.
American journal of physiology. Heart and circulatory physiology
Zisa D,Shabbir A,Mastri M,Taylor T,Aleksic I,McDaniel M,Suzuki G,Lee T
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
Sox3 functions in a cell-autonomous manner to regulate spermatogonial differentiation in mice.
Endocrinology
Laronda MM,Jameson JL
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Apr 01 00:00:00 EDT 2011
Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche.
Experimental hematology
Jung Y,Shiozawa Y,Wang J,Patel LR,Havens AM,Song J,Krebsbach PH,Roodman GD,Taichman RS
25-1171 was used in Magnetic cell separation to investigate the role that annexin-2 plays in presenting stromal cell-derived factor-1 to hematopoietic stem cells.
Tue Feb 01 00:00:00 EST 2011
A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors.
Lipids
Varney ME,Buchanan JT,Dementieva Y,Hardman WE,Sollars VE
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2011
Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway.
PloS one
Heinonen KM,Vanegas JR,Lew D,Krosl J,Perreault C
25-1171 was used in Flow cytometry/Cell sorting to establish a functional role for non-canonical Wnt signalling in hematopoiesis through a pathway involving Wnt4, Fz6, Rac1 and Jnk kinases.
Tue Apr 26 00:00:00 EDT 2011
Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment.
The Journal of experimental medicine
Morita Y,Ema H,Nakauchi H
25-1171 was used in Immunofluorescence to highlight the complexity and hierarchy of reconstitution capability among HSCs in mice.
Mon Jun 07 00:00:00 EDT 2010
Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells.
The Journal of experimental medicine
Edelson BT,KC W,Juang R,Kohyama M,Benoit LA,Klekotka PA,Moon C,Albring JC,Ise W,Michael DG,Bhattacharya D,Stappenbeck TS,Holtzman MJ,Sung SS,Murphy TL,Hildner K,Murphy KM
25-1171 was used in Flow cytometry/Cell sorting to study the relationship between nonlymphoid CD103-expressing dendritic cells (DCs) and other DC subsets.
Mon Apr 12 00:00:00 EDT 2010
Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential.
Cell stem cell
Benveniste P,Frelin C,Janmohamed S,Barbara M,Herrington R,Hyam D,Iscove NN
25-1171 was used in Flow cytometry/Cell sorting to investigate the presence of "intermediate-term" multipotent hematopoietic stem cells, revealing that these cells are able to sustain clones of differentiating cells for only 4-6 weeks.
Fri Jan 08 00:00:00 EST 2010
Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimen.
American journal of physiology. Heart and circulatory physiology
Shabbir A,Zisa D,Suzuki G,Lee T
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2009
Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow.
Stem cells (Dayton, Ohio)
Singh P,Yao Y,Weliver A,Broxmeyer HE,Hong SC,Chang CH
25-1171 was used in Flow cytometry/Cell sorting to show that in vivo VV infection results in the expansion of c-Kit(hi)Sca-1+Lin- (KSL) haematopoietic stem cells.
Tue Apr 01 00:00:00 EDT 2008
Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis.
Molecular and cellular biology
Wen R,Chen Y,Bai L,Fu G,Schuman J,Dai X,Zeng H,Yang C,Stephan RP,Cleveland JL,Wang D
Published figure using CD117 (c-Kit) monoclonal antibody (Product # 25-1171-82) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2006