Invitrogen

CD11b Monoclonal Antibody (M1/70), PE-Cyanine5, eBioscience™

FIGURE: 1 / 99

CD11b Antibody (15-0112-82) in Flow

Staining of mouse bone marrow cells with 0.06 µg of Rat IgG2b K Isotype Control PE-Cyanine5 (Product # 15-4031-82) (blue histogram) or 0.06 µg of Anti-Mouse CD11b PE-Cyanine5 (purple histogram).Cells in the large scatter population were used for analysis.

Product Image Gallery

Product Details

15-0112-82

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

0.125 µg/test

View 287 publications 287 publications

Product Specifications

Species Reactivity

Mouse

Published species

Fish, Human, Mouse

Host/Isotype

Rat / IgG2b, kappa

Recommended Isotype Control

Rat IgG2b kappa Isotype Control (eB149/10H5), PE-Cyanine5, eBioscience™

Class

Monoclonal

Type

Antibody

Clone

M1/70

Conjugate

PE-Cyanine5 PE-Cyanine5 PE-Cyanine5

Excitation/Emission Max

568/666 nm View spectra

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_468714

Product Specific Information

Description: The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaM-beta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.

Applications Reported: The M1/70 antibody has been reported for use in flow cytometric analysis.

Applications Tested: The M1/70 antibody has been tested by flow cytometric analysis of mouse splenocytes and bone marrow cells. This can be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Light sensitivity: This tandem dye is sensitive photo-induced oxidation. Please protect this vial and stained samples from light.

Fixation: Samples can be stored in IC Fixation Buffer (Product # 00-822-49) (100 µL cell sample + 100 µL IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product # 00-5333-54) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.

Excitation: 488-561 nm; Emission: 667 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

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Cell death & disease

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Cell death & disease

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Experimental & molecular medicine

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Nature communications

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Nature communications

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British journal of pharmacology

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Nature communications

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STAR protocols

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Sun Aug 01 00:00:00 EDT 2021

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Nature communications

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Cells

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Frontiers in pharmacology

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Sat Apr 02 00:00:00 EDT 2022

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Cellular and molecular gastroenterology and hepatology

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Physiological reports

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Sat May 01 00:00:00 EDT 2021

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Nature communications

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Cell reports

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PloS one

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Frontiers in immunology

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Theranostics

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Protocol for single-cell ATAC sequencing using combinatorial indexing in mouse lung adenocarcinoma.

STAR protocols

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15-0112-82 was used in Flow Cytometry to show that sciATAC-seq is a cost-effective, extensible strategy that permits flexibility in the experimental scale via multiplexed barcoding across samples or perturbations.

Fri Jun 18 00:00:00 EDT 2021

Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.

Journal of neuroinflammation

Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Feb 18 00:00:00 EST 2021

Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).

PloS one

Lin CK,Huang TH,Yang CT,Shi CS

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Oct 12 00:00:00 EDT 2021

Systemic administration of β-glucan induces immune training in microglia.

Journal of neuroinflammation

Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Feb 22 00:00:00 EST 2021

Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.

Nano-micro letters

Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sat Nov 21 00:00:00 EST 2020

IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.

Arteriosclerosis, thrombosis, and vascular biology

Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2020

Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.

British journal of pharmacology

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Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sat Feb 01 00:00:00 EST 2020

Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.

Mucosal immunology

Wang C,Li Q,Lv J,Sun X,Cao Y,Yu K,Miao C,Zhang ZS,Yao Z,Wang Q

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model.

Glia

Boeck M,Thien A,Wolf J,Hagemeyer N,Laich Y,Yusuf D,Backofen R,Zhang P,Boneva S,Stahl A,Hilgendorf I,Agostini H,Prinz M,Wieghofer P,Schlunck G,Schlecht A,Lange C

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2020

Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection.

Journal of leukocyte biology

Zhao Y,Li Z,Su L,Ballesteros-Tato A,Katz J,Michalek SM,Feng X,Zhang P

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

Mouse bone marrow mesenchymal stem cells with distinct p53 statuses display differential characteristics.

Molecular medicine reports

Wang B,Wang L,Mao J,Wen H,Xu L,Ren Y,Du H,Yang H

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri May 01 00:00:00 EDT 2020

Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.

BioMed research international

Jiang JK,Hong LJ,Lu YQ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Dec 16 00:00:00 EST 2020

Irradiation induces cancer lung metastasis through activation of the cGAS-STING-CCL5 pathway in mesenchymal stromal cells.

Cell death & disease

Zheng Z,Jia S,Shao C,Shi Y

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu May 07 00:00:00 EDT 2020

Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure.

Frontiers in immunology

Hsu CY,Lin YC,Chang LY,Huang SK,Huang CH,Yang CK,Huang CT,Lin CY

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jun 15 00:00:00 EDT 2021

Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.

Journal of clinical & cellular immunology

Alkhateeb T,Bah I,Kumbhare A,Youssef D,Yao ZQ,McCall CE,Gazzar ME

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sat Aug 13 00:00:00 EDT 2022

The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.

Nature communications

Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Sep 17 00:00:00 EDT 2020

Exploring the Role of Osteosarcoma-Derived Extracellular Vesicles in Pre-Metastatic Niche Formation and Metastasis in the 143-B Xenograft Mouse Osteosarcoma Model.

Cancers

Mazumdar A,Urdinez J,Boro A,Arlt MJE,Egli FE,Niederöst B,Jaeger PK,Moschini G,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Nov 20 00:00:00 EST 2020

Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization.

Frontiers in immunology

Chandran S,Schilke RM,Blackburn CMR,Yurochko A,Mirza R,Scott RS,Finck BN,Woolard MD

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Mar 29 00:00:00 EDT 2021

Ly6c^Lo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.

Scientific reports

Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Apr 28 00:00:00 EDT 2020

Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.

Cancers

Kuziel G,Thompson V,D'Amato JV,Arendt LM

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jul 28 00:00:00 EDT 2020

The immune response after noise damage in the cochlea is characterized by a heterogeneous mix of adaptive and innate immune cells.

Scientific reports

Rai V,Wood MB,Feng H,Schabla NM,Tu S,Zuo J

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Sep 16 00:00:00 EDT 2020

Macrophage-Associated Lipin-1 Promotes β-Oxidation in Response to Proresolving Stimuli.

ImmunoHorizons

Schilke RM,Blackburn CMR,Rao S,Krzywanski DM,Finck BN,Woolard MD

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Oct 19 00:00:00 EDT 2020

TNFAIP3 Plays a Role in Aging of the Hematopoietic System.

Frontiers in immunology

Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Apr 28 00:00:00 EDT 2021

TNFAIP3 Plays a Role in Aging of the Hematopoietic System.

Frontiers in immunology

Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Apr 28 00:00:00 EDT 2021

Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.

eLife

Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Dec 02 00:00:00 EST 2020

CD103⁺ cDC1 and endogenous CD8⁺ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.

Nature communications

Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Dec 02 00:00:00 EST 2020

Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System.

Biomedicines

Hong Y,Singh N,Bamopoulos S,Gjerga E,Schmalbrock LK,Balabanian K,Schick M,Keller U,Wirth M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Dec 09 00:00:00 EST 2020

The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing.

Cell death & disease

Hu HJ,Liang X,Li HL,Du CM,Hao JL,Wang HY,Gu JF,Ni AM,Sun LY,Xiao J,Hu JQ,Yuan H,Dai YS,Jin XT,Zhang KJ,Liu XY

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Nov 30 00:00:00 EST 2020

L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men.

Cells

Drescher HK,Schippers A,Rosenhain S,Gremse F,Bongiovanni L,Bruin A,Eswaran S,Gallage SU,Pfister D,Szydlowska M,Heikenwalder M,Weiskirchen S,Wagner N,Trautwein C,Weiskirchen R,Kroy DC

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Apr 29 00:00:00 EDT 2020

Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.

JCI insight

Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Aug 20 00:00:00 EDT 2020

Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.

Frontiers in immunology

Hering L,Katkeviciute E,Schwarzfischer M,Busenhart P,Gottier C,Mrdjen D,Komuczki J,Wawrzyniak M,Lang S,Atrott K,Becher B,Rogler G,Scharl M,Spalinger MR

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Apr 12 00:00:00 EDT 2021

Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.

Nature communications

Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Aug 27 00:00:00 EDT 2020

Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells.

JCI insight

Hadas R,Gershon E,Cohen A,Atrakchi O,Lazar S,Golani O,Dassa B,Elbaz M,Cohen G,Eilam R,Dekel N,Neeman M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Nov 19 00:00:00 EST 2020

Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b⁺Ly6G^- myeloid cells.

Aging

Fang Y,Gu Y,Li L,Zhu L,Qian J,Zhao C,Xu L,Wei W,Du Y,Yuan N,Zhang S,Yuan Y,Xu Y,Jiang C,Wang J

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Nov 24 00:00:00 EST 2020

Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.

Cells

Nuti E,Rossello A,Cuffaro D,Camodeca C,Van Bael J,van der Maat D,Martens E,Fiten P,Pereira RVS,Ugarte-Berzal E,Gouwy M,Opdenakker G,Vandooren J

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jul 07 00:00:00 EDT 2020

Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.

Stem cell research & therapy

Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Nov 27 00:00:00 EST 2020

GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.

Cells

Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Jan 03 00:00:00 EST 2020

Differential Activation of Macrophages Based on Their Environment in Advanced Age.

Chonnam medical journal

Lee DY,Lim JS,Cho KA

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

G protein-coupled receptor 68 increases the number of B lymphocytes.

American journal of blood research

He X,Feng S,Hawkins C,Lawley L,Fan W,Xu Y,Zha XM,Fang J

15-0112 was used in Flow cytometry/Cell sorting to indicate that Gpr68 expression is upregulated in hematopoietic cells upon aging and during hematopoietic regeneration that ends up with increased number of B lymphocytes.

Mon Sep 28 00:00:00 EDT 2020

Methamphetamine induces cardiomyopathy by Sigmar1 inhibition-dependent impairment of mitochondrial dynamics and function.

Communications biology

Abdullah CS,Aishwarya R,Alam S,Morshed M,Remex NS,Nitu S,Kolluru GK,Traylor J,Miriyala S,Panchatcharam M,Hartman B,King J,Bhuiyan MAN,Chandran S,Woolard MD,Yu X,Goeders NE,Dominic P,Arnold CL,Stokes K,Kevil CG,Orr AW,Bhuiyan MS

15-0112-82 was used in Flow Cytometry to show that Sigmar1 is a therapeutic target for methamphetamine-associated cardiomyopathy.

Tue Nov 17 00:00:00 EST 2020

Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.

Frontiers in pharmacology

Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Feb 16 00:00:00 EST 2021

Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice.

Nature immunology

Piliponsky AM,Shubin NJ,Lahiri AK,Truong P,Clauson M,Niino K,Tsuha AL,Nedospasov SA,Karasuyama H,Reber LL,Tsai M,Mukai K,Galli SJ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Feb 01 00:00:00 EST 2019

Central nervous system regeneration is driven by microglia necroptosis and repopulation.

Nature neuroscience

Lloyd AF,Davies CL,Holloway RK,Labrak Y,Ireland G,Carradori D,Dillenburg A,Borger E,Soong D,Richardson JC,Kuhlmann T,Williams A,Pollard JW,des Rieux A,Priller J,Miron VE

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Jul 01 00:00:00 EDT 2019

Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages.

British journal of pharmacology

Feng L,Sun Y,Song P,Xu L,Wu X,Wu X,Shen Y,Sun Y,Kong L,Wu X,Xu Q

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jan 01 00:00:00 EST 2019

Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models.

Breast cancer research : BCR

Sabol RA,Bowles AC,Côté A,Wise R,O'Donnell B,Matossian MD,Hossain FM,Burks HE,Del Valle L,Miele L,Collins-Burow BM,Burow ME,Bunnell BA

15-0112 was used in Flow cytometry/Cell sorting to study the mechanisms by which obesity promotes tumour progression.

Wed May 22 00:00:00 EDT 2019

Distinct Tie2 tyrosine phosphorylation sites dictate phenotypic switching in endothelial progenitor cells.

Journal of cellular physiology

Siavashi V,Nassiri SM,Rahbarghazi R,Mohseni Z,Sharifi AM

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed May 01 00:00:00 EDT 2019

Antiallodynic Effects of Cannabinoid Receptor 2 (CB₂R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.

Pain research & management

Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Dec 16 00:00:00 EST 2019

Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.

Anti-cancer drugs

Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice.

Cell reports

Zeng J,Wang Y,Luo Z,Chang LC,Yoo JS,Yan H,Choi Y,Xie X,Deverman BE,Gradinaru V,Gupton SL,Zlokovic BV,Zhao Z,Jung JU

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Apr 09 00:00:00 EDT 2019

Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis.

Nature communications

Zhang X,Zhang H,Xu C,Li X,Li M,Wu X,Pu W,Zhou B,Wang H,Li D,Ding Q,Ying H,Wang H,Zhang H

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Sep 13 00:00:00 EDT 2019

Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine.

Scientific reports

Kimura H,Imura YK,Tomiyasu H,Mihara T,Kaji N,Ohno K,Unno T,Tanahashi Y,Jan TR,Tsubone H,Ozaki H,Hori M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Apr 10 00:00:00 EDT 2019

MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.

Journal for immunotherapy of cancer

Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Nov 28 00:00:00 EST 2019

Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.

Cellular and molecular gastroenterology and hepatology

Cipriani G,Terhaar ML,Eisenman ST,Ji S,Linden DR,Wright AM,Sha L,Ordog T,Szurszewski JH,Gibbons SJ,Farrugia G

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jun 04 00:00:00 EDT 2019

Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.

Frontiers in immunology

Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Oct 14 00:00:00 EDT 2020

Exposure to Cigarette Smoke Augments Post-ischemic Brain Injury and Inflammation via Mobilization of Neutrophils and Monocytes.

Frontiers in immunology

Li H,Li X,Gao S,Wang D,Gao X,Li Y,Wang X,Cui Z,Ma H,Liu Q,Li M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Sep 28 00:00:00 EDT 2020

Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity.

Nature metabolism

Seo JB,Riopel M,Cabrales P,Huh JY,Bandyopadhyay GK,Andreyev AY,Murphy AN,Beeman SC,Smith GI,Klein S,Lee YS,Olefsky JM

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jan 01 00:00:00 EST 2019

Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.

Nature communications

Kurelac I,Iommarini L,Vatrinet R,Amato LB,De Luise M,Leone G,Girolimetti G,Umesh Ganesh N,Bridgeman VL,Ombrato L,Columbaro M,Ragazzi M,Gibellini L,Sollazzo M,Feichtinger RG,Vidali S,Baldassarre M,Foriel S,Vidone M,Cossarizza A,Grifoni D,Kofler B,Malanchi I,Porcelli AM,Gasparre G

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Feb 22 00:00:00 EST 2019

Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche.

Cell reports

Balzano M,De Grandis M,Vu Manh TP,Chasson L,Bardin F,Farina A,Sergé A,Bidaut G,Charbord P,Hérault L,Bailly AL,Cartier-Michaud A,Boned A,Dalod M,Duprez E,Genever P,Coles M,Bajenoff M,Xerri L,Aurrand-Lions M,Schiff C,Mancini SJC

15-0112 was used in Flow cytometry/Cell sorting to study pro-B cells in their support of stroll cells and their interaction network allowing their retention.

Tue Mar 19 00:00:00 EDT 2019

N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells.

Cell reports

Zhao M,Tao F,Venkatraman A,Li Z,Smith SE,Unruh J,Chen S,Ward C,Qian P,Perry JM,Marshall H,Wang J,He XC,Li L

15-0112 was used in Flow cytometry/Cell sorting to report that N-cad+ cells were functional bone and marrow stromal progenitor cells, giving rise to osteoblasts, adipocytes, and chondrocytes both in vitro and in vivo.

Tue Jan 15 00:00:00 EST 2019

Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR.

Nature communications

Zhu H,Bhatt B,Sivaprakasam S,Cai Y,Liu S,Kodeboyina SK,Patel N,Savage NM,Sharma A,Kaufman RJ,Li H,Singh N

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Mar 06 00:00:00 EST 2019

The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response.

Scientific reports

Tellez Freitas CM,Burrell HR,Valdoz JC,Hamblin GJ,Raymond CM,Cox TD,Johnson DK,Andersen JL,Weber KS,Bridgewater LC

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Jan 30 00:00:00 EST 2019

Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.

Nature communications

Galle-Treger L,Sankaranarayanan I,Hurrell BP,Howard E,Lo R,Maazi H,Lewis G,Banie H,Epstein AL,Hu P,Rehan VK,Gilliland FD,Allayee H,Soroosh P,Sharpe AH,Akbari O

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Feb 12 00:00:00 EST 2019

Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells.

Cellular and molecular gastroenterology and hepatology

Kiyohara H,Sujino T,Teratani T,Miyamoto K,Arai MM,Nomura E,Harada Y,Aoki R,Koda Y,Mikami Y,Mizuno S,Naganuma M,Hisamatsu T,Kanai T

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Apr 29 00:00:00 EDT 2019

Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.

Nature communications

Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Nov 28 00:00:00 EST 2019

Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells.

Nature

Kim HS,Tan Y,Ma W,Merkurjev D,Destici E,Ma Q,Suter T,Ohgi K,Friedman M,Skowronska-Krawczyk D,Rosenfeld MG

15-0112 was used in Immunocytochemistry-Immunofluorescence to examine the hierarchical and obligate premarking of cell-type-restricted enhancers in embryonic stem cells.

Sun Apr 01 00:00:00 EDT 2018

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.

Nature

Morioka S,Perry JSA,Raymond MH,Medina CB,Zhu Y,Zhao L,Serbulea V,Onengut-Gumuscu S,Leitinger N,Kucenas S,Rathmell JC,Makowski L,Ravichandran KS

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Nov 01 00:00:00 EDT 2018

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

Nature

Meisel M,Hinterleitner R,Pacis A,Chen L,Earley ZM,Mayassi T,Pierre JF,Ernest JD,Galipeau HJ,Thuille N,Bouziat R,Buscarlet M,Ringus DL,Wang Y,Li Y,Dinh V,Kim SM,McDonald BD,Zurenski MA,Musch MW,Furtado GC,Lira SA,Baier G,Chang EB,Eren AM,Weber CR,Busque L,Godley LA,Verdú EF,Barreiro LB,Jabri B

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue May 01 00:00:00 EDT 2018

LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.

Nature

Peltzer N,Darding M,Montinaro A,Draber P,Draberova H,Kupka S,Rieser E,Fisher A,Hutchinson C,Taraborrelli L,Hartwig T,Lafont E,Haas TL,Shimizu Y,Böiers C,Sarr A,Rickard J,Alvarez-Diaz S,Ashworth MT,Beal A,Enver T,Bertin J,Kaiser W,Strasser A,Silke J,Bouillet P,Walczak H

15-0112-82 was used in Flow cytometry/Cell sorting to demonstrate that both linear ubiquitin chain assembly complex components HOIP and HOIL-1, are required for embryogenesis by preventing cell death.

Tue May 01 00:00:00 EDT 2018

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.

Cell

Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Jan 25 00:00:00 EST 2018

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.

Cell

Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Jun 28 00:00:00 EDT 2018

Chanzyme TRPM7 Mediates the Ca²⁺ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.

Immunity

Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jan 16 00:00:00 EST 2018

E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.

Immunity

Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Feb 20 00:00:00 EST 2018

Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.

Immunity

Hirota K,Hashimoto M,Ito Y,Matsuura M,Ito H,Tanaka M,Watanabe H,Kondoh G,Tanaka A,Yasuda K,Kopf M,Potocnik AJ,Stockinger B,Sakaguchi N,Sakaguchi S

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jun 19 00:00:00 EDT 2018

Insulin resistance causes inflammation in adipose tissue.

The Journal of clinical investigation

Shimobayashi M,Albert V,Woelnerhanssen B,Frei IC,Weissenberger D,Meyer-Gerspach AC,Clement N,Moes S,Colombi M,Meier JA,Swierczynska MM,Jenö P,Beglinger C,Peterli R,Hall MN

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Apr 02 00:00:00 EDT 2018

Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease.

The Journal of clinical investigation

Tsantikos E,Lau M,Castelino CM,Maxwell MJ,Passey SL,Hansen MJ,McGregor NE,Sims NA,Steinfort DP,Irving LB,Anderson GP,Hibbs ML

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Jun 01 00:00:00 EDT 2018

Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney.

Journal of the American Society of Nephrology : JASN

Micanovic R,Khan S,Janosevic D,Lee ME,Hato T,Srour EF,Winfree S,Ghosh J,Tong Y,Rice SE,Dagher PC,Wu XR,El-Achkar TM

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Mar 01 00:00:00 EST 2018

11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.

Journal of autoimmunity

Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Aug 01 00:00:00 EDT 2018

MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.

Proceedings of the National Academy of Sciences of the United States of America

Suarez-Lopez L,Sriram G,Kong YW,Morandell S,Merrick KA,Hernandez Y,Haigis KM,Yaffe MB

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue May 01 00:00:00 EDT 2018

Long Non-Coding RNA HOXA Transcript Antisense RNA Myeloid-Specific 1-HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer.

Frontiers in immunology

Tian X,Ma J,Wang T,Tian J,Zhang Y,Mao L,Xu H,Wang S

15-0112 was used in Flow cytometry/Cell sorting to conclude that HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) downregulates the immunosuppressive function of myeloid-derived suppressor cells by targeting HOXA1, providing a potential therapeutic target in lung cancer.

Mon Jun 24 00:00:00 EDT 2019

VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.

Glia

Borggrewe M,Grit C,Den Dunnen WFA,Burm SM,Bajramovic JJ,Noelle RJ,Eggen BJL,Laman JD

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sat Dec 01 00:00:00 EST 2018

Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes.

Journal of cellular physiology

Liron T,Raphael B,Hiram-Bab S,Bab IA,Gabet Y

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Jan 01 00:00:00 EST 2018

Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sun Apr 01 00:00:00 EDT 2018

Frontline Science: Macrophage-derived exosomes promote neutrophil necroptosis following hemorrhagic shock.

Journal of leukocyte biology

Jiao Y,Li Z,Loughran PA,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Shi X,Fan J

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

The Outcome of the Cryptococcus neoformans-Macrophage Interaction Depends on Phagolysosomal Membrane Integrity.

Journal of immunology (Baltimore, Md. : 1950)

De Leon-Rodriguez CM,Rossi DCP,Fu MS,Dragotakes Q,Coelho C,Guerrero Ros I,Caballero B,Nolan SJ,Casadevall A

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sun Jul 15 00:00:00 EDT 2018

Dysregulation of Kupffer Cells/Macrophages and Natural Killer T Cells in Steatohepatitis in LXRα Knockout Male Mice.

Endocrinology

Endo-Umeda K,Nakashima H,Umeda N,Seki S,Makishima M

Thu Mar 01 00:00:00 EST 2018

Primary cilia disruption differentially affects the infiltrating and resident macrophage compartment in the liver.

American journal of physiology. Gastrointestinal and liver physiology

Zimmerman KA,Song CJ,Gonzalez-Mize N,Li Z,Yoder BK

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Jun 01 00:00:00 EDT 2018

Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice.

Molecular medicine reports

Wang X,Zhang Y,Wang Z,Liu X,Zhu G,Han G,Chen G,Hou C,Wang T,Shen B,Li Y,Xiao H,Ma N,Wang R

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Jan 01 00:00:00 EST 2018

A novel method to isolate mesenchymal stem cells from mouse umbilical cord.

Molecular medicine reports

Zhang B,Zhang J,Shi H,Mao F,Wang J,Yan Y,Zhang X,Qian H,Xu W

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Jan 01 00:00:00 EST 2018

Simultaneous isolation of mesenchymal stem cells and endothelial progenitor cells derived from murine bone marrow.

Experimental and therapeutic medicine

Wang X,Zhao Z,Zhang H,Hou J,Feng W,Zhang M,Guo J,Xia J,Ge Q,Chen X,Wu X

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sat Dec 01 00:00:00 EST 2018

Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis.

Cell stem cell

Qian P,De Kumar B,He XC,Nolte C,Gogol M,Ahn Y,Chen S,Li Z,Xu H,Perry JM,Hu D,Tao F,Zhao M,Han Y,Hall K,Peak A,Paulson A,Zhao C,Venkatraman A,Box A,Perera A,Haug JS,Parmely T,Li H,Krumlauf R,Li L

15-0112 was used in Flow cytometry/Cell sorting to demonstrate roles for retinoid signaling and the DERARE in maintaining HSCs and preventing leukemogenesis by coordinate regulation of Hoxb genes.

Thu May 03 00:00:00 EDT 2018

iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.

JCI insight

Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Feb 08 00:00:00 EST 2018

Targeting the gut microbiome to treat the osteoarthritis of obesity.

JCI insight

Schott EM,Farnsworth CW,Grier A,Lillis JA,Soniwala S,Dadourian GH,Bell RD,Doolittle ML,Villani DA,Awad H,Ketz JP,Kamal F,Ackert-Bicknell C,Ashton JM,Gill SR,Mooney RA,Zuscik MJ

15-0112 was used in Flow cytometry/Cell sorting to show that reducing Tnf-associated inflammation in obesity is profoundly protective against osteoarthritis in mice.

Thu Apr 19 00:00:00 EDT 2018

A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.

Nature communications

Wang T,Wang D,Yu H,Feng B,Zhou F,Zhang H,Zhou L,Jiao S,Li Y

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Apr 18 00:00:00 EDT 2018

Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.

Frontiers in immunology

Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Sep 25 00:00:00 EDT 2019

Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.

Journal of neuroinflammation

Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Sep 21 00:00:00 EDT 2018

Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.

Oncotarget

Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Apr 24 00:00:00 EDT 2018

BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells.

Oncotarget

Romano E,Rufo N,Korf H,Mathieu C,Garg AD,Agostinis P

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Apr 03 00:00:00 EDT 2018

An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages.

Scientific reports

Beneke V,Küster F,Neehus AL,Hesse C,Lopez-Rodriguez E,Haake K,Rafiei Hashtchin A,Schott JW,Walter D,Braun A,Wolkers WF,Ackermann M,Lachmann N

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Nov 02 00:00:00 EDT 2018

Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.

Frontiers in physiology

Lim D,Kim W,Lee C,Bae H,Kim J

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Sep 30 00:00:00 EDT 2020

RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.

The Journal of biological chemistry

Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Jun 15 00:00:00 EDT 2018

JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression.

Nature medicine

Zhao X,Guo Y,Jiang C,Chang Q,Zhang S,Luo T,Zhang B,Jia X,Hung MC,Dong C,Lin X

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.

Nature

Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Apr 06 00:00:00 EDT 2017

A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.

Nature

Tammela T,Sanchez-Rivera FJ,Cetinbas NM,Wu K,Joshi NS,Helenius K,Park Y,Azimi R,Kerper NR,Wesselhoeft RA,Gu X,Schmidt L,Cornwall-Brady M,Yilmaz ÖH,Xue W,Katajisto P,Bhutkar A,Jacks T

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu May 18 00:00:00 EDT 2017

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia.

Cancer cell

Reyna DE,Garner TP,Lopez A,Kopp F,Choudhary GS,Sridharan A,Narayanagari SR,Mitchell K,Dong B,Bartholdy BA,Walensky LD,Verma A,Steidl U,Gavathiotis E

15-0112 was used in Flow cytometry/Cell sorting to identify BTSA1, a pharmacologically optimised BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.

Mon Oct 09 00:00:00 EDT 2017

Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria.

Cell host & microbe

Jiang TT,Shao TY,Ang WXG,Kinder JM,Turner LH,Pham G,Whitt J,Alenghat T,Way SS

15-0112-82 was used in Flow Cytometry to show that commensal fungi can functionally replace intestinal bacteria by conferring protection against injury to mucosal tissues and positively calibrating the responsiveness of circulating immune cells.

Wed Dec 13 00:00:00 EST 2017

Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.

Nature immunology

Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2017

Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.

Nature immunology

Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2017

A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.

The Journal of clinical investigation

Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.

The EMBO journal

Kawasaki T,Ito K,Miyata H,Akira S,Kawai T

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Jun 14 00:00:00 EDT 2017

Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.

Proceedings of the National Academy of Sciences of the United States of America

Bao Y,Wu X,Chen J,Hu X,Zeng F,Cheng J,Jin H,Lin X,Chen LF

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue May 16 00:00:00 EDT 2017

CCR2^- and CCR2⁺ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.

Mucosal immunology

Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Sep 01 00:00:00 EDT 2017

Depletion of microglia exacerbates postischemic inflammation and brain injury.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo.

Journal of virology

Ding Q,von Schaewen M,Hrebikova G,Heller B,Sandmann L,Plaas M,Ploss A

15-0112 was used in Flow cytometry/Cell sorting to demonstrate that minimally humanized mice develop normally, express the modified genes at physiological levels, and support Hepatitis C virus uptake.

Wed Feb 15 00:00:00 EST 2017

Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Wang W,Wang H,Zhou X,Li X,Sun W,Dellinger M,Boyce BF,Xing L

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

Lung Epithelial Cell-Derived Microvesicles Regulate Macrophage Migration via MicroRNA-17/221-Induced Integrin β₁ Recycling.

Journal of immunology (Baltimore, Md. : 1950)

Lee H,Zhang D,Wu J,Otterbein LE,Jin Y

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Aug 15 00:00:00 EDT 2017

Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.

International journal of molecular medicine

Zhang B,Wang B,Cao S,Wang Y,Wu D

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.

RNA biology

Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu May 04 00:00:00 EDT 2017

β3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche.

Journal of cellular biochemistry

Vafaei R,Nassiri SM,Siavashi V

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Dec 01 00:00:00 EST 2017

Growth inhibition of formed corneal neovascularization following Fosaprepitant treatment.

Acta ophthalmologica

Bignami F,Lorusso A,Rama P,Ferrari G

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Nov 01 00:00:00 EDT 2017

Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron-Like SH-SY5Y and Microglia-Like BV2.

Alcoholism, clinical and experimental research

Lawrimore CJ,Crews FT

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer.

Oncotarget

Zamanian-Daryoush M,Lindner DJ,DiDonato JA,Wagner M,Buffa J,Rayman P,Parks JS,Westerterp M,Tall AR,Hazen SL

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Sep 22 00:00:00 EDT 2017

Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment.

Scientific reports

Yeku OO,Purdon TJ,Koneru M,Spriggs D,Brentjens RJ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Sep 05 00:00:00 EDT 2017

MiR-125a Is a critical modulator for neutrophil development.

PLoS genetics

Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sun Oct 01 00:00:00 EDT 2017

Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury.

Stem cell research & therapy

Zhu D,Tan J,Maleken AS,Muljadi R,Chan ST,Lau SN,Elgass K,Leaw B,Mockler J,Chambers D,Leeman KT,Kim CF,Wallace EM,Lim R

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Nov 10 00:00:00 EST 2017

Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.

Oncotarget

Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Dec 12 00:00:00 EST 2017

Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.

Cell death & disease

Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity.

NPJ vaccines

Stephen J,Scales HE,Benson RA,Erben D,Garside P,Brewer JM

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Apr 08 00:00:00 EDT 2022

In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.

Particle and fibre toxicology

Jatana S,Palmer BC,Phelan SJ,Gelein R,DeLouise LA

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Apr 14 00:00:00 EDT 2017

Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.

JCI insight

Kienhöfer D,Hahn J,Stoof J,Csepregi JZ,Reinwald C,Urbonaviciute V,Johnsson C,Maueröder C,Podolska MJ,Biermann MH,Leppkes M,Harrer T,Hultqvist M,Olofsson P,Munoz LE,Mocsai A,Herrmann M,Schett G,Holmdahl R,Hoffmann MH

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu May 18 00:00:00 EDT 2017

Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation.

Nature communications

Xu Y,Wang Y,Yan S,Yang Q,Zhou Y,Zeng X,Liu Z,An X,Toque HA,Dong Z,Jiang X,Fulton DJ,Weintraub NL,Li Q,Bagi Z,Hong M,Boison D,Wu C,Huo Y

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Oct 16 00:00:00 EDT 2017

CIITA-driven MHC class II expressing tumor cells can efficiently prime naive CD4⁺ TH cells in vivo and vaccinate the host against parental MHC-II-negative tumor cells.

Oncoimmunology

Bou Nasser Eddine F,Forlani G,Lombardo L,Tedeschi A,Tosi G,Accolla RS

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2021

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.

JCI insight

Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Sep 21 00:00:00 EDT 2017

Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.

Cell

Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Oct 06 00:00:00 EDT 2016

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.

Cell

Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Aug 25 00:00:00 EDT 2016

Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.

Nature immunology

Esterházy D,Loschko J,London M,Jove V,Oliveira TY,Mucida D

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Oligodendrocyte death results in immune-mediated CNS demyelination.

Nature neuroscience

Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Jan 01 00:00:00 EST 2016

The breast tumor microenvironment alters the phenotype and function of natural killer cells.

Cellular & molecular immunology

Krneta T,Gillgrass A,Chew M,Ashkar AA

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Alternatively activated macrophages determine repair of the infarcted adult murine heart.

The Journal of clinical investigation

Shiraishi M,Shintani Y,Shintani Y,Ishida H,Saba R,Yamaguchi A,Adachi H,Yashiro K,Suzuki K

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Jun 01 00:00:00 EDT 2016

ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages.

Frontiers in immunology

Zha QB,Wei HX,Li CG,Liang YD,Xu LH,Bai WJ,Pan H,He XH,Ouyang DY

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Nov 20 00:00:00 EST 2019

Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.

Stem cells translational medicine

Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.

Immunology

Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sat Oct 01 00:00:00 EDT 2016

Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype.

Journal of ginseng research

Ren K,Jin C,Ma P,Ren Q,Jia Z,Zhu D

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.

Disease models & mechanisms

Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Regenerative Potential of Mesenchymal Stromal Cells: Age-Related Changes.

Stem cells international

Bruna F,Contador D,Conget P,Erranz B,Sossa CL,Arango-Rodríguez ML

15-0112 was used in Flow cytometry/Cell sorting to suggest, the treatment with adult''s BM-MSCs or their acd-MSCs in cutaneous wound promotes a better tissue repair/regeneration.

Wed Jun 01 00:00:00 EDT 2016

ECM-Dependence of Endothelial Progenitor Cell Features.

Journal of cellular biochemistry

Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Aug 01 00:00:00 EDT 2016

Tlr2 on Bone Marrow and Non-Bone Marrow Derived Cells Regulates Inflammation and Organ Injury in Cooperation with Tlr4 During Resuscitated Hemorrhagic Shock.

Shock (Augusta, Ga.)

Korff S,Loughran P,Cai C,Fan J,Elson G,Shang L,Pires SS,Lee YS,Guardado J,Scott M,Billiar TR

15-0112 was used in Flow cytometry/Cell sorting to conclude that TLR2 and TLR4 act together as important receptors in the host immune response to hemorrhagic shock and resuscitation.

Tue Nov 01 00:00:00 EDT 2016

Sertoli cell condition medium can induce germ like cells from bone marrow derived mesenchymal stem cells.

Iranian journal of basic medical sciences

Monfared MH,Minaee B,Rastegar T,Khrazinejad E,Barbarestani M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Nov 01 00:00:00 EDT 2016

Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.

Stem cell reports

Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Aug 09 00:00:00 EDT 2016

Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.

Cell death & disease

Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Jul 28 00:00:00 EDT 2016

Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.

Oncoimmunology

Vila-Leahey A,Oldford SA,Marignani PA,Wang J,Haidl ID,Marshall JS

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Jul 01 00:00:00 EDT 2016

CpG-oligodeoxynucleotides exert remarkable antitumor activity against diffuse malignant peritoneal mesothelioma orthotopic xenografts.

Journal of translational medicine

De Cesare M,Sfondrini L,Pennati M,De Marco C,Motta V,Tagliabue E,Deraco M,Balsari A,Zaffaroni N

15-0112 was used in Flow cytometry/Cell sorting to indicate that locally administered CpG-ODN1826 is able to markedly affect the growth of both early- and late-stage DMPM orthotopic xenografts in the absence of severe side effects.

Mon Jan 25 00:00:00 EST 2016

Interleukin 6 regulates psoriasiform inflammation-associated thrombosis.

JCI insight

Wang Y,Golden JB,Fritz Y,Zhang X,Diaconu D,Camhi MI,Gao H,Dawes SM,Xing X,Ganesh SK,Gudjonsson JE,Simon DI,McCormick TS,Ward NL

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Dec 08 00:00:00 EST 2016

Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity.

PloS one

Jonas BA,Johnson C,Gratzinger D,Majeti R

15-0112 was used in Flow cytometry/Cell sorting to report several new t-AML/MDS mouse models that could potentially be used to further define disease pathogenesis and test novel therapeutics.

Wed Jul 26 00:00:00 EDT 2017

Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.

Aging

McCullough LD,Mirza MA,Xu Y,Bentivegna K,Steffens EB,Ritzel R,Liu F

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Jul 01 00:00:00 EDT 2016

NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.

Nature communications

Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Sep 07 00:00:00 EDT 2016

The impact of ranitidine on monocyte responses in the context of solid tumors.

Oncotarget

Vila-Leahey A,Rogers D,Marshall JS

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Mar 08 00:00:00 EST 2016

Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice.

Scientific reports

Watari K,Shibata T,Nabeshima H,Shinoda A,Fukunaga Y,Kawahara A,Karasuyama K,Fukushi J,Iwamoto Y,Kuwano M,Ono M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Jan 18 00:00:00 EST 2016

Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.

Oncoimmunology

Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2016

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.

Scientific reports

Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Jun 15 00:00:00 EDT 2016

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.

Nature medicine

Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2015

Host microbiota constantly control maturation and function of microglia in the CNS.

Nature neuroscience

Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

Blood

Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Nov 19 00:00:00 EST 2015

Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1.

The Journal of clinical investigation

Fond AM,Lee CS,Schulman IG,Kiss RS,Ravichandran KS

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.

The Journal of clinical investigation

Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Nov 02 00:00:00 EST 2015

Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.

The Journal of clinical investigation

Henry CJ,Casás-Selves M,Kim J,Zaberezhnyy V,Aghili L,Daniel AE,Jimenez L,Azam T,McNamee EN,Clambey ET,Klawitter J,Serkova NJ,Tan AC,Dinarello CA,DeGregori J

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Dec 01 00:00:00 EST 2015

STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.

The Journal of clinical investigation

Li W,Xiao J,Zhou X,Xu M,Hu C,Xu X,Lu Y,Liu C,Xue S,Nie L,Zhang H,Li Z,Zhang Y,Ji F,Hui L,Tao W,Wei B,Wang H

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Nov 02 00:00:00 EST 2015

Hepatic DNA deposition drives drug-induced liver injury and inflammation in mice.

Hepatology (Baltimore, Md.)

Marques PE,Oliveira AG,Pereira RV,David BA,Gomides LF,Saraiva AM,Pires DA,Novaes JT,Patricio DO,Cisalpino D,Menezes-Garcia Z,Leevy WM,Chapman SE,Mahecha G,Marques RE,Guabiraba R,Martins VP,Souza DG,Mansur DS,Teixeira MM,Leite MF,Menezes GB

15-0112 was used in Flow cytometry/Cell sorting to examine whether DNA released from damaged hepatocytes accumulates into necrotic liver, and study the impact of its recognition by the immune system.

Thu Jan 01 00:00:00 EST 2015

Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.

Brain : a journal of neurology

Natrajan MS,de la Fuente AG,Crawford AH,Linehan E,Nuñez V,Johnson KR,Wu T,Fitzgerald DC,Ricote M,Bielekova B,Franklin RJ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Dec 01 00:00:00 EST 2015

Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.

Journal of the American Society of Nephrology : JASN

Micanovic R,Chitteti BR,Dagher PC,Srour EF,Khan S,Hato T,Lyle A,Tong Y,Wu XR,El-Achkar TM

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Cis-regulatory mechanisms governing stem and progenitor cell transitions.

Science advances

Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency.

Glia

Verheijden S,Beckers L,Casazza A,Butovsky O,Mazzone M,Baes M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Aging-like changes in the transcriptome of irradiated microglia.

Glia

Li MD,Burns TC,Kumar S,Morgan AA,Sloan SA,Palmer TD

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri May 01 00:00:00 EDT 2015

Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.

PLoS pathogens

Wiesner DL,Specht CA,Lee CK,Smith KD,Mukaremera L,Lee ST,Lee CG,Elias JA,Nielsen JN,Boulware DR,Bohjanen PR,Jenkins MK,Levitz SM,Nielsen K

15-0112 was used in Flow cytometry/Cell sorting to investigate Th2 cell responses to pulmonary fungal infection, showing that chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.

Sun Mar 01 00:00:00 EST 2015

Yersinia pestis targets neutrophils via complement receptor 3.

Cellular microbiology

Merritt PM,Nero T,Bohman L,Felek S,Krukonis ES,Marketon MM

15-0112 was used in Flow cytometry/Cell sorting to identify the factors involved in the targeting of murine splenocytes by Yersinia pestis.

Fri May 01 00:00:00 EDT 2015

Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.

Tissue engineering. Part A

Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Apr 01 00:00:00 EDT 2015

Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.

Molecular medicine reports

Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.

BioMed research international

Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Aug 01 00:00:00 EDT 2016

Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.

The Journal of biological chemistry

Pamir N,Liu NC,Irwin A,Becker L,Peng Y,Ronsein GE,Bornfeldt KE,Duffield JS,Heinecke JW

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Jun 05 00:00:00 EDT 2015

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.

Nature communications

Koh HS,Chang CY,Jeon SB,Yoon HJ,Ahn YH,Kim HS,Kim IH,Jeon SH,Johnson RS,Park EJ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Mar 20 00:00:00 EDT 2015

Mouse CD11b+Kupffer Cells Recruited from Bone Marrow Accelerate Liver Regeneration after Partial Hepatectomy.

PloS one

Nishiyama K,Nakashima H,Ikarashi M,Kinoshita M,Nakashima M,Aosasa S,Seki S,Yamamoto J

15-0112 was used in Flow cytometry/Cell sorting to investigate the role of Kupffer cells in liver regeneration after partial hepatectomy in mice.

Mon May 23 00:00:00 EDT 2016

Sleep disruption impairs haematopoietic stem cell transplantation in mice.

Nature communications

Rolls A,Pang WW,Ibarra I,Colas D,Bonnavion P,Korin B,Heller HC,Weissman IL,de Lecea L

15-0112 was used in Flow cytometry/Cell sorting to provide insights into cellular and molecular mechanisms underlying the effects of sleep deprivation on HSCs.

Wed Oct 14 00:00:00 EDT 2015

Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.

Nature communications

Balasubramani A,Larjo A,Bassein JA,Chang X,Hastie RB,Togher SM,Lähdesmäki H,Rao A

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Jun 22 00:00:00 EDT 2015

Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.

PloS one

Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2016

dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.

Nature communications

Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Sep 15 00:00:00 EDT 2015

Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.

Stem cell reports

Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Oct 13 00:00:00 EDT 2015

Pathogenic Yersinia Promotes Its Survival by Creating an Acidic Fluid-Accessible Compartment on the Macrophage Surface.

PloS one

Bahnan W,Boettner DR,Westermark L,Fällman M,Schesser K

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue May 10 00:00:00 EDT 2016

Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.

Oncoimmunology

Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2015

Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma.

Nature communications

Lee CL,Castle KD,Moding EJ,Blum JM,Williams N,Luo L,Ma Y,Borst LB,Kim Y,Kirsch DG

15-0112 was used in Flow cytometry/Cell sorting to show that total-body irradiation promotes the expansion of a rare population of thymocytes that express oncogenic Kras(G12D).

Thu Sep 24 00:00:00 EDT 2015

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.

Nature

Colegio OR,Chu NQ,Szabo AL,Chu T,Rhebergen AM,Jairam V,Cyrus N,Brokowski CE,Eisenbarth SC,Phillips GM,Cline GW,Phillips AJ,Medzhitov R

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Sep 25 00:00:00 EDT 2014

Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.

Cell

Haldar M,Kohyama M,So AY,Kc W,Wu X,Briseño CG,Satpathy AT,Kretzer NM,Arase H,Rajasekaran NS,Wang L,Egawa T,Igarashi K,Baltimore D,Murphy TL,Murphy KM

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Mar 13 00:00:00 EDT 2014

A role for the ITAM signaling module in specifying cytokine-receptor functions.

Nature immunology

Bezbradica JS,Rosenstein RK,DeMarco RA,Brodsky I,Medzhitov R

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Apr 01 00:00:00 EDT 2014

RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma.

Cancer research

Chen X,Zhang L,Zhang IY,Liang J,Wang H,Ouyang M,Wu S,da Fonseca ACC,Weng L,Yamamoto Y,Yamamoto H,Natarajan R,Badie B

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Dec 15 00:00:00 EST 2014

Macrophages contribute to the cyclic activation of adult hair follicle stem cells.

PLoS biology

Castellana D,Paus R,Perez-Moreno M

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Dec 01 00:00:00 EST 2014

Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice.

Glia

Cekanaviciute E,Fathali N,Doyle KP,Williams AM,Han J,Buckwalter MS

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Aug 01 00:00:00 EDT 2014

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.

Development (Cambridge, England)

Gilmour J,Assi SA,Jaegle U,Kulu D,van de Werken H,Clarke D,Westhead DR,Philipsen S,Bonifer C

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sun Jun 01 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu May 01 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu May 01 00:00:00 EDT 2014

Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology.

Journal of immunology (Baltimore, Md. : 1950)

El-Zaatari M,Chang YM,Zhang M,Franz M,Shreiner A,McDermott AJ,van der Sluijs KF,Lutter R,Grasberger H,Kamada N,Young VB,Huffnagle GB,Kao JY

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Jul 15 00:00:00 EDT 2014

CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury.

Journal of neurotrauma

Hsieh CL,Niemi EC,Wang SH,Lee CC,Bingham D,Zhang J,Cozen ML,Charo I,Huang EJ,Liu J,Nakamura MC

15-0112 was used in Flow cytometry/Cell sorting to suggest that therapeutic blockade of CCR2-dependent responses may improve outcomes following traumatic brain injury (TBI).

Wed Oct 15 00:00:00 EDT 2014

Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages.

Journal of neuroimmunology

Carvalho da Fonseca AC,Wang H,Fan H,Chen X,Zhang I,Zhang L,Lima FR,Badie B

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Sep 15 00:00:00 EDT 2014

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.

Nature communications

Chen L,Gibbons DL,Goswami S,Cortez MA,Ahn YH,Byers LA,Zhang X,Yi X,Dwyer D,Lin W,Diao L,Wang J,Roybal J,Patel M,Ungewiss C,Peng D,Antonia S,Mediavilla-Varela M,Robertson G,Suraokar M,Welsh JW,Erez B,Wistuba II,Chen L,Peng D,Wang S,Ullrich SE,Heymach JV,Kurie JM,Qin FX

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Oct 28 00:00:00 EDT 2014

Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.

PloS one

Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu May 28 00:00:00 EDT 2015

Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.

Molecular cancer

Doloff JC,Chen CS,Waxman DJ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Jun 26 00:00:00 EDT 2014

Influenza virus-induced lung inflammation was modulated by cigarette smoke exposure in mice.

PloS one

Han Y,Ling MT,Mao H,Zheng J,Liu M,Lam KT,Liu Y,Tu W,Lau YL

15-0112 was used in Flow cytometry/Cell sorting to investigate the effect of cigarette smoke on pandemic H1N1 or H9N2 virus infection, showing that virus-induced lung inflammation was modulated by cigarette smoke exposure.

Wed Oct 29 00:00:00 EDT 2014

Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.

PloS one

Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Wed Jun 10 00:00:00 EDT 2015

P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica.

PloS one

Monção-Ribeiro LC,Faffe DS,Santana PT,Vieira FS,da Graça CL,Marques-da-Silva C,Machado MN,Caruso-Neves C,Zin WA,Borojevic R,Takiya CM,Coutinho-Silva R

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Sep 17 00:00:00 EDT 2015

The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.

The Journal of biological chemistry

Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Feb 14 00:00:00 EST 2014

The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.

The Journal of biological chemistry

Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Feb 14 00:00:00 EST 2014

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction.

Nature medicine

Shi L,Cui S,Engel JD,Tanabe O

15-0112 was used in Flow cytometry/Cell sorting to examine the effect of lysine-specific demethylase 1 inhibition on the expression of foetal γ-globin.

Fri Mar 01 00:00:00 EST 2013

FOXO3A directs a protective autophagy program in haematopoietic stem cells.

Nature

Warr MR,Binnewies M,Flach J,Reynaud D,Garg T,Malhotra R,Debnath J,Passegué E

15-0112 was used in Flow cytometry/Cell sorting to show how FOXO3A directs a protective autophagy program in haematopoietic stem cells.

Thu Feb 21 00:00:00 EST 2013

miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.

Nature cell biology

Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Mar 01 00:00:00 EST 2013

S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages.

Clinical cancer research : an official journal of the American Association for Cancer Research

Wang H,Zhang L,Zhang IY,Chen X,Da Fonseca A,Wu S,Ren H,Badie S,Sadeghi S,Ouyang M,Warden CD,Badie B

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Jul 15 00:00:00 EDT 2013

A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils.

Developmental cell

Zhang Y,Tang W,Zhang H,Niu X,Xu Y,Zhang J,Gao K,Pan W,Boggon TJ,Toomre D,Min W,Wu D

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Oct 28 00:00:00 EDT 2013

Traumatic brain injury induces macrophage subsets in the brain.

European journal of immunology

Hsieh CL,Kim CC,Ryba BE,Niemi EC,Bando JK,Locksley RM,Liu J,Nakamura MC,Seaman WE

15-0112 was used in Flow cytometry/Cell sorting to better understand the mechanisms involved in the innate inflammatory responses to brain injury.

Thu Aug 01 00:00:00 EDT 2013

Coactivator-associated arginine methyltransferase 1 regulates fetal hematopoiesis and thymocyte development.

Journal of immunology (Baltimore, Md. : 1950)

Li J,Zhao Z,Carter C,Ehrlich LI,Bedford MT,Richie ER

15-0112 was used in Flow cytometry/Cell sorting to demonstrate how CARM1 is a key epigenetic regulator of hematopoiesis that affects multiple lineages at various stages of differentiation.

Tue Jan 15 00:00:00 EST 2013

Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration.

The Journal of comparative neurology

Lampron A,Pimentel-Coelho PM,Rivest S

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Sun Dec 01 00:00:00 EST 2013

The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.

The Journal of biological chemistry

Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Jul 19 00:00:00 EDT 2013

Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation.

PloS one

Ma S,Richardson JA,Bitmansour A,Solberg TD,Pidikiti R,Song K,Stojadinovic S,Vitetta ES,Meyer JJ

15-0112 was used in Flow cytometry/Cell sorting to investigate the effects of partial depletion of regulatory T cells alongside ionizing radiation on inflammation and tissue injury in mice.

Mon Jul 29 00:00:00 EDT 2013

G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses.

Journal of hematology & oncology

Rubinstein MP,Salem ML,Doedens AL,Moore CJ,Chiuzan C,Rivell GL,Cole DJ,Goldrath AW

15-0112 was used in Flow cytometry/Cell sorting to evaluate whether the biological activity of G-CSF can be improved by pre-association with anti-G-CSF monoclonal antibodies prior to injection.

Tue Oct 01 00:00:00 EDT 2013

Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris.

The Journal of biological chemistry

Fernandez-Castaneda A,Arandjelovic S,Stiles TL,Schlobach RK,Mowen KA,Gonias SL,Gaultier A

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Feb 15 00:00:00 EST 2013

Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.

Blood

He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Oct 11 00:00:00 EDT 2012

Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.

The Journal of clinical investigation

Johnson KD,Hsu AP,Ryu MJ,Wang J,Gao X,Boyer ME,Liu Y,Lee Y,Calvo KR,Keles S,Zhang J,Holland SM,Bresnick EH

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Mon Oct 01 00:00:00 EDT 2012

Metalloproteinase-mediated Shedding of Integrin β2 promotes macrophage efflux from inflammatory sites.

The Journal of biological chemistry

Gomez IG,Tang J,Wilson CL,Yan W,Heinecke JW,Harlan JM,Raines EW

15-0112 was used in an ELISA assay to investigate peritonitis-elevated levels of integrin β2 at times when macrophages are exiting the peritoneum.

Fri Feb 10 00:00:00 EST 2012

A nonpeptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages.

Chemistry & biology

Verdoes M,Edgington LE,Scheeren FA,Leyva M,Blum G,Weiskopf K,Bachmann MH,Ellman JA,Bogyo M

15-0112 was used in Flow cytometry/Cell sorting to study how BMV083 may be a valuable in vivo reporter for tumor-associated macrophages.

Fri May 25 00:00:00 EDT 2012

Induction of histiocytic sarcoma in mouse skeletal muscle.

PloS one

Liu J,Hettmer S,Milsom MD,Hofmann I,Hua F,Miller C,Bronson RT,Wagers AJ

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Thu Feb 07 00:00:00 EST 2013

Requirement for complement in antibody responses is not explained by the classic pathway activator IgM.

Proceedings of the National Academy of Sciences of the United States of America

Rutemark C,Alicot E,Bergman A,Ma M,Getahun A,Ellmerich S,Carroll MC,Heyman B

15-0112 was used in Flow cytometry/Cell sorting to investigate the role of the classical pathway activator IgM in complement activated antibody responses.

Tue Oct 25 00:00:00 EDT 2011

Plasmodium falciparum: differential merozoite dose requirements for maximal production of various inflammatory cytokines.

Experimental parasitology

Wu X,Gowda NM,Gowda DC

15-0112 was used in Flow cytometry/Cell sorting to investigate differential merozoite dose requirements for maximal production of various inflammatory cytokines in Plasmodium falciparum.

Sat Jan 01 00:00:00 EST 2011

PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.

PloS one

Hemmers S,Teijaro JR,Arandjelovic S,Mowen KA

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Tue Nov 15 00:00:00 EST 2011

An information theoretic, microfluidic-based single cell analysis permits identification of subpopulations among putatively homogeneous stem cells.

PloS one

Glotzbach JP,Januszyk M,Vial IN,Wong VW,Gelbard A,Kalisky T,Thangarajah H,Longaker MT,Quake SR,Chu G,Gurtner GC

15-0112 was used in Flow cytometry/Cell sorting to develop a novel method to characterize and predict transcriptional programs across individual homogeneous stem cells.

Wed Nov 02 00:00:00 EDT 2011

Measles virus infection of alveolar macrophages and dendritic cells precedes spread to lymphatic organs in transgenic mice expressing human signaling lymphocytic activation molecule (SLAM, CD150).

Journal of virology

Ferreira CS,Frenzke M,Leonard VH,Welstead GG,Richardson CD,Cattaneo R

15-0112 was used in Flow cytometry/Cell sorting to identify the cells that support primary measles infection before systemic spread.

Mon Mar 01 00:00:00 EST 2010

Additive and global functions of HoxA cluster genes in mesoderm derivatives.

Developmental biology

Di-Poï N,Koch U,Radtke F,Duboule D

15-0112 was used in Flow cytometry/Cell sorting to report that mutant mice lacking the entire HoxA cluster in mesodermal lineages display the expected spectrum of postnatal respiratory, cardiac and urogenital defects, previously reported for single gene mutations.

Sat May 15 00:00:00 EDT 2010

Stromal cell independent B cell development in vitro: generation and recovery of autoreactive clones.

Journal of immunological methods

Holl TM,Haynes BF,Kelsoe G

15-0112 was used in Flow cytometry/Cell sorting to describe a stromal cell independent culture system that efficiently supports pro-B cell to IgM+ B cell development with near normal levels of IgH and Igkappa diversity.

Wed Mar 31 00:00:00 EDT 2010

Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model.

Arthritis and rheumatism

Jacobs JP,Ortiz-Lopez A,Campbell JJ,Gerard CJ,Mathis D,Benoist C

15-0112 was used in Flow cytometry/Cell sorting to investigate chemokines and their receptors in the effector phase of arthritis.

Thu Jul 01 00:00:00 EDT 2010

Dynamics of T cell, antigen-presenting cell, and pathogen interactions during recall responses in the lymph node.

Immunity

Chtanova T,Han SJ,Schaeffer M,van Dooren GG,Herzmark P,Striepen B,Robey EA

15-0112 was used in Flow cytometry/Cell sorting to provide insight into cellular interactions during recall responses and suggest a mechanism of pathogen subversion of the immune response.

Fri Aug 21 00:00:00 EDT 2009

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.

Cell stem cell

Le Grand F,Jones AE,Seale V,Scimè A,Rudnicki MA

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Jun 05 00:00:00 EDT 2009

Dynamic imaging of T cell-parasite interactions in the brains of mice chronically infected with Toxoplasma gondii.

Journal of immunology (Baltimore, Md. : 1950)

Schaeffer M,Han SJ,Chtanova T,van Dooren GG,Herzmark P,Chen Y,Roysam B,Striepen B,Robey EA

15-0112 was used in Flow cytometry/Cell sorting to directly observe the dynamics of T cell-parasite interactions within living tissue and further understand immune responses to persistent pathogens in the brain.

Fri May 15 00:00:00 EDT 2009

Dynamics of neutrophil migration in lymph nodes during infection.

Immunity

Chtanova T,Schaeffer M,Han SJ,van Dooren GG,Nollmann M,Herzmark P,Chan SW,Satija H,Camfield K,Aaron H,Striepen B,Robey EA

15-0112 was used in Flow cytometry/Cell sorting to provide insight into the cellular mechanisms underlying neutrophil swarming and suggest new roles for neutrophils in shaping immune responses.

Fri Sep 19 00:00:00 EDT 2008

Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis.

The Journal of biological chemistry

Chen Y,Wang X,Di L,Fu G,Chen Y,Bai L,Liu J,Feng X,McDonald JM,Michalek S,He Y,Yu M,Fu YX,Wen R,Wu H,Wang D

Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry

Fri Oct 24 00:00:00 EDT 2008

Stable form of JAB1 enhances proliferation and maintenance of hematopoietic progenitors.

The Journal of biological chemistry

Mori M,Yoneda-Kato N,Yoshida A,Kato JY

15-0112 was used in Flow cytometry/Cell sorting to investigate how the expression and function of JAB1 are critical for the proliferation and maintenance of hematopoietic progenitors.

Fri Oct 24 00:00:00 EDT 2008

The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging.

Blood

Dumble M,Moore L,Chambers SM,Geiger H,Van Zant G,Goodell MA,Donehower LA

15-0112 was used in Flow cytometry/Cell sorting to study how altering p53 dosage during ageing impacts hematopoietic stem cell dynamics.

Thu Feb 15 00:00:00 EST 2007

Immature hematopoietic cells display selective requirements for adhesion- and degranulation-promoting adaptor protein in development and homeostatsis.

European journal of immunology

Dluzniewska J,Zou L,Harmon IR,Ellingson MT,Peterson EJ

15-0112-82 was used in Flow Cytometry to highlight the dynamic regulation of ADAP during T cell maturation and document expression patterns that suggest a possible role for ADAP in development of non-T hematopoietic lineages.

Thu Nov 01 00:00:00 EDT 2007

Developmental switch of mouse hematopoietic stem cells from fetal to adult type occurs in bone marrow after birth.

Proceedings of the National Academy of Sciences of the United States of America

Kikuchi K,Kondo M

15-0112 was used in Flow cytometry/Cell sorting to demonstrate how foetal haematopoietic stem cells may acquire adult characteristics between 1 and 2 weeks after birth in mouse bone marrow.

Tue Nov 21 00:00:00 EST 2006

Beta-catenin is dispensable for hematopoiesis and lymphopoiesis.

The Journal of experimental medicine

Cobas M,Wilson A,Ernst B,Mancini SJ,MacDonald HR,Kemler R,Radtke F

15-0112 was used in Flow cytometry/Cell sorting to investigate an essential role for beta-catenin during hematopoiesis and lymphopoiesis.

Mon Jan 19 00:00:00 EST 2004

Bioinformatics

Protein Aliases: CD11 antigen-like family member B; CD11B (p170); cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component receptor 3 alpha-a; complement receptor type 3; CR-3 alpha chain; integrin alpha-M; leukocyte adhesion receptor MO1; Mac-1 alpha; Mac-1 alpha (Mac1A); macrophage antigen alpha; MGC117044

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Gene Aliases: Cd11b; CD11b/CD18; CR3; CR3A; F730045J24Rik; Ly-40; Mac-1; Mac-1a; MAC1

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Entrez Gene ID: (Mouse) 16409

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Function(s)

opsonin binding glycoprotein binding heparin binding heparan sulfate proteoglycan binding metal ion binding protein heterodimerization activity integrin

Process(es)

leukocyte migration involved in inflammatory response cell adhesion leukocyte cell-cell adhesion integrin-mediated signaling pathway microglia development single organismal cell-cell adhesion neutrophil chemotaxis cellular extravasation activated T cell proliferation

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CD11b Monoclonal Antibody (M1/70), PE-Cyanine5, eBioscience™

CD11b Antibody (15-0112-82) in Flow

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15-0112-82

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