Product References
Role of Nox4 in Mitigating Inflammation and Fibrosis in Dextran Sulfate Sodium-Induced Colitis.
Cellular and molecular gastroenterology and hepatology
Lee Y,Kim SH,Jeong H,Kim KH,Jeon D,Cho Y,Lee D,Nam KT
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Immunohistochemistry
Tue Aug 22 00:00:00 EDT 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
MicroRNA‑21‑5p protects melanocytes via targeting STAT3 and modulating Treg/Teff balance to alleviate vitiligo.
Molecular medicine reports
Huo J,Liu T,Li F,Song X,Hou X
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice.
JCI insight
Yun JH,Lee C,Liu T,Liu S,Kim EY,Xu S,Curtis JL,Pinello L,Bowler RP,Silverman EK,Hersh CP,Zhou X
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Wed Sep 08 00:00:00 EDT 2021
RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes.
Frontiers in immunology
Rana A,de Almeida FC,Paico Montero HA,Gonzales Carazas MM,Bortoluci KR,Sad S,Amarante-Mendes GP
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials.
Immunity
Xu W,Cherrier DE,Chea S,Vosshenrich C,Serafini N,Petit M,Liu P,Golub R,Di Santo JP
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Nature immunology
Twohig JP,Cardus Figueras A,Andrews R,Wiede F,Cossins BC,Derrac Soria A,Lewis MJ,Townsend MJ,Millrine D,Li J,Hill DG,Uceda Fernandez J,Liu X,Szomolay B,Pepper CJ,Taylor PR,Pitzalis C,Tiganis T,Williams NM,Jones GW,Jones SA
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2019
Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis.
Haematologica
Zhang Z,Huang Z,Ong B,Sahu C,Zeng H,Ruan HB
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2019
Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells.
Cell reports
Magen A,Nie J,Ciucci T,Tamoutounour S,Zhao Y,Mehta M,Tran B,McGavern DB,Hannenhalli S,Bosselut R
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Tue Dec 03 00:00:00 EST 2019
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
The interplay of BMP4 and IL‑7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia̸reperfusion.
International journal of molecular medicine
Luo B,Chen K,Feng Q,Xiao W,Ma D,Yang H,Zhang C
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Immunoregulation by IL-7R-targeting antibody-drug conjugates: overcoming steroid-resistance in cancer and autoimmune disease.
Scientific reports
Yasunaga M,Manabe S,Matsumura Y
16-1271 was used in Flow cytometry to suggest that the cytotoxicity and immunosuppressive capacity of A7R-ADC could be modulated to treat specific malignancies or autoimmune diseases through the introduction of different payloads, and represents a novel alternative to steroid therapy.
Wed Sep 06 00:00:00 EDT 2017
WASH maintains NKp46+ ILC3 cells by promoting AHR expression.
Nature communications
Xia P,Liu J,Wang S,Ye B,Du Y,Xiong Z,Han ZG,Tong L,Fan Z
16-1271 was used in Flow cytometry/Cell sorting to study how WASH-mediated AHR expression has a critical function in the maintenance of NKp46(+) ILC3s.
Wed Jun 07 00:00:00 EDT 2017
A simple, accurate and universal method for quantification of PCR.
BMC biotechnology
Boulter N,Suarez FG,Schibeci S,Sunderland T,Tolhurst O,Hunter T,Hodge G,Handelsman D,Simanainen U,Hendriks E,Duggan K
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Wed Mar 09 00:00:00 EST 2016
Phenotype and Hierarchy of Two Transgenic T Cell Lines Targeting the Respiratory Syncytial Virus KdM282-90 Epitope Is Transfer Dose-Dependent.
PloS one
Morabito KM,Erez N,Graham BS,Ruckwardt TJ
16-1271 was used in Flow cytometry/Cell sorting to compare the immune response to respiratory syncytial virus infection following adoptive transfer of two transgenic CD8+ T cell lines.
Tue Jul 19 00:00:00 EDT 2016
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Nature immunology
Laidlaw BJ,Cui W,Amezquita RA,Gray SM,Guan T,Lu Y,Kobayashi Y,Flavell RA,Kleinstein SH,Craft J,Kaech SM
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2015
mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.
The Journal of clinical investigation
Pollizzi KN,Patel CH,Sun IH,Oh MH,Waickman AT,Wen J,Delgoffe GM,Powell JD
16-1271 was used in Flow cytometry/Cell sorting to define specific roles for mTORC1 and mTORC2 in the specification of immune cell subsets.
Fri May 01 00:00:00 EDT 2015
Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence.
The Journal of experimental medicine
Nakagawa MM,Thummar K,Mandelbaum J,Pasqualucci L,Rathinam CV
16-1271 was used in Flow cytometry/Cell sorting to investigate the critical regulatory role of the ubiquitin-editing enzyme A20, and the impact of A20 deficiency in the hematopoietic system.
Mon Feb 09 00:00:00 EST 2015
The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.
Genes & development
Miyazaki M,Miyazaki K,Chen S,Chandra V,Wagatsuma K,Agata Y,Rodewald HR,Saito R,Chang AN,Varki N,Kawamoto H,Murre C
16-1271 was used in Flow cytometry/Cell sorting to show that Id2 and Id3 suppress the development and expansion of innate variant follicular helper T cells.
Sun Feb 15 00:00:00 EST 2015
IL-22-Expressing Murine Lymphocytes Display Plasticity and Pathogenicity in Reporter Mice.
Frontiers in immunology
Shen W,Hixon JA,McLean MH,Li WQ,Durum SK
16-1271 was used in Flow cytometry/Cell sorting to identify and explore the function, plasticity, pathogenicity and location of IL-22-expressing lymphocytes in reporter mice.
Tue Feb 02 00:00:00 EST 2016
Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.
PLoS pathogens
Pascutti MF,Geerman S,Slot E,van Gisbergen KP,Boon L,Arens R,van Lier RA,Wolkers MC,Nolte MA
16-1271 was used in Flow cytometry/Cell sorting to study resolution of chronic viral infection through GITR-mediated co-stimulation enhancing CD8 T cell responses.
Sun Mar 01 00:00:00 EST 2015
CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection.
Infection and immunity
Durward-Diioia M,Harms J,Khan M,Hall C,Smith JA,Splitter GA
16-1271 was used in Flow cytometry/Cell sorting to assess the populations of immune cells which respond to chronic infection of Brucella melitensis.
Tue Dec 01 00:00:00 EST 2015
Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100.
Blood
Lee CE,Fulcher DA,Whittle B,Chand R,Fewings N,Field M,Andrews D,Goodnow CC,Cook MC
16-1271 was used in Flow cytometry/Cell sorting to report 3 related individuals with a novel form of severe B-cell deficiency associated with partial persistence of serum immunoglobulin arising from a missense mutation in NFKB2.
Thu Nov 06 00:00:00 EST 2014
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival.
Mucosal immunology
Webster KE,Kim HO,Kyparissoudis K,Corpuz TM,Pinget GV,Uldrich AP,Brink R,Belz GT,Cho JH,Godfrey DI,Sprent J
16-1271 was used in Flow cytometry/Cell sorting to elucidate the factors that maintain the natural killer T cell population in the periphery.
Mon Sep 01 00:00:00 EDT 2014
IL-2 induction of Blimp-1 is a key in vivo signal for CD8+ short-lived effector T cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Boulet S,Daudelin JF,Labrecque N
16-1271 was used in Flow cytometry/Cell sorting to demonstrate that IL-2 induction of Blimp-1 expression is a key regulator of short-lived effector cell differentiation.
Fri Aug 15 00:00:00 EDT 2014
Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells.
eLife
Sojka DK,Plougastel-Douglas B,Yang L,Pak-Wittel MA,Artyomov MN,Ivanova Y,Zhong C,Chase JM,Rothman PB,Yu J,Riley JK,Zhu J,Tian Z,Yokoyama WM
16-1271 was used in Flow cytometry/Cell sorting to investigate whether tissue-resident and cells resembling conventional splenic natural killer cells natural killer cells are derived from the same lineage, showing that there are at least four distinct lineages.
Wed Jan 01 00:00:00 EST 2014
Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros.
Nature immunology
Schjerven H,McLaughlin J,Arenzana TL,Frietze S,Cheng D,Wadsworth SE,Lawson GW,Bensinger SJ,Farnham PJ,Witte ON,Smale ST
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2013
Aged mice exhibit a severely diminished CD8 T cell response following respiratory syncytial virus infection.
Journal of virology
Fulton RB,Weiss KA,Pewe LL,Harty JT,Varga SM
16-1271 was used in Flow cytometry/Cell sorting to investigate the extent to which CD8 T cell response to respiratory syncytial virus is altered with age, showing that age severely diminishes response.
Sun Dec 01 00:00:00 EST 2013
Alcam regulates long-term hematopoietic stem cell engraftment and self-renewal.
Stem cells (Dayton, Ohio)
Jeannet R,Cai Q,Liu H,Vu H,Kuo YH
16-1271 was used in Flow cytometry/Cell sorting to investigate the role of activated leukocyte cell adhesion molecule in hematopoietic stem cell differentiation and self-renewal using an Alcam-null mouse model.
Fri Mar 01 00:00:00 EST 2013
Temporal requirements for B cells in the establishment of CD4 T cell memory.
Journal of immunology (Baltimore, Md. : 1950)
Mollo SB,Zajac AJ,Harrington LE
16-1271 was used in Flow cytometry/Cell sorting to demonstrate the temporally and functionally distinct roles for B cells in regulating CD4 T cell responses.
Sun Dec 15 00:00:00 EST 2013
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.
Immunity
Roberts NA,White AJ,Jenkinson WE,Turchinovich G,Nakamura K,Withers DR,McConnell FM,Desanti GE,Benezech C,Parnell SM,Cunningham AF,Paolino M,Penninger JM,Simon AK,Nitta T,Ohigashi I,Takahama Y,Caamano JH,Hayday AC,Lane PJ,Jenkinson EJ,Anderson G
16-1271 was used in Immunofluorescence to study the temporal development of Vγ5(+) γδ T cells during thymus medulla formation.
Fri Mar 23 00:00:00 EDT 2012
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.
Nature immunology
Ochiai K,Maienschein-Cline M,Mandal M,Triggs JR,Bertolino E,Sciammas R,Dinner AR,Clark MR,Singh H
Published figure using CD127 monoclonal antibody (Product # 16-1271-85) in Flow Cytometry
Sun Jan 22 00:00:00 EST 2012
Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Do JS,Valujskikh A,Vignali DA,Fairchild RL,Min B
16-1271 was used in Flow cytometry/Cell sorting to reveal a previously undefined MHC II-dependent regulation that tunes CD8 T-cell reactivity.
Tue Jul 31 00:00:00 EDT 2012
CD8 T cells recruited early in mouse polyomavirus infection undergo exhaustion.
Journal of immunology (Baltimore, Md. : 1950)
Wilson JJ,Pack CD,Lin E,Frost EL,Albrecht JA,Hadley A,Hofstetter AR,Tevethia SS,Schell TD,Lukacher AE
16-1271 was used in Flow cytometry/Cell sorting to characterise virus-specific CD8 T cells recruited during persistent infection.
Tue May 01 00:00:00 EDT 2012
Extra-thymic physiological T lineage progenitor activity is exclusively confined to cells expressing either CD127, CD90, or high levels of CD117.
PloS one
Saran N,Pommerencke J,Witzlau K,Regelin M,Krueger A
16-1271 was used in Flow cytometry/Cell sorting to suggest that a physiological thymic microenvironment does not optimally support T cell differentiation from triple negative precursors.
Mon Jun 18 00:00:00 EDT 2012
TGF-β sensitivity restrains CD8+ T cell homeostatic proliferation by enforcing sensitivity to IL-7 and IL-15.
PloS one
Johnson LD,Jameson SC
16-1271 was used in Flow cytometry/Cell sorting to analyse the response of transgenic naive CD8+ T cells with impaired TGF-β sensitivity to lymphopenia.
Thu Jan 10 00:00:00 EST 2013
Dicer insufficiency and microRNA-155 overexpression in lupus regulatory T cells: an apparent paradox in the setting of an inflammatory milieu.
Journal of immunology (Baltimore, Md. : 1950)
Divekar AA,Dubey S,Gangalum PR,Singh RR
16-1271 was used in Flow cytometry/Cell sorting to investigate mechanisms of potential Treg cell defects in systemic lupus erythematosus.
Sat Jan 15 00:00:00 EST 2011
SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells.
Journal of immunology (Baltimore, Md. : 1950)
Fowler CC,Pao LI,Blattman JN,Greenberg PD
16-1271 was used in Flow cytometry/Cell sorting to investigate the role of SHP-1 in shaping responses of mature CD8 T cells in vivo.
Wed Sep 15 00:00:00 EDT 2010
Mast cell degranulation breaks peripheral tolerance.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
de Vries VC,Wasiuk A,Bennett KA,Benson MJ,Elgueta R,Waldschmidt TJ,Noelle RJ
16-1271 was used in Flow cytometry/Cell sorting to show that intragraft or systemic mast cell degranulation results in the transient loss of Treg suppressor activities and the rejection of established allografts.
Thu Oct 01 00:00:00 EDT 2009
LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen.
Journal of immunology (Baltimore, Md. : 1950)
Vondenhoff MF,Greuter M,Goverse G,Elewaut D,Dewint P,Ware CF,Hoorweg K,Kraal G,Mebius RE
Fri May 01 00:00:00 EDT 2009
STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells.
Journal of immunology (Baltimore, Md. : 1950)
Archambaud C,Sansoni A,Mingueneau M,Devilard E,Delsol G,Malissen B,Malissen M
16-1271 was used in Flow cytometry/Cell sorting to study the effect of STAT6 delection on Lat(Y136F) mice.
Sun Mar 01 00:00:00 EST 2009
Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines.
Blood
Ahonen CL,Wasiuk A,Fuse S,Turk MJ,Ernstoff MS,Suriawinata AA,Gorham JD,Kedl RM,Usherwood EJ,Noelle RJ
16-1271 was used in Flow cytometry/Cell sorting to report the therapeutic effects of combinatorial use of CD40 and TLR agonists as a cancer vaccine.
Sat Mar 15 00:00:00 EDT 2008
CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming.
The Journal of experimental medicine
Martín-Fontecha A,Baumjohann D,Guarda G,Reboldi A,Hons M,Lanzavecchia A,Sallusto F
16-1271 was used in Flow cytometry/Cell sorting to show that T(EM) cells can behave as endogenous adjuvants.
Mon Oct 27 00:00:00 EDT 2008
Identification of a T lineage-committed progenitor in adult blood.
Immunity
Krueger A,von Boehmer H
16-1271 was used in Flow cytometry/Cell sorting to show that CTP represent T lineage-committed T cell precursors linking extrathymic with intrathymic lymphopoiesis in adult mice.
Mon Jan 01 00:00:00 EST 2007
The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.
Genes & development
Iwasaki H,Mizuno S,Arinobu Y,Ozawa H,Mori Y,Shigematsu H,Takatsu K,Tenen DG,Akashi K
16-1271 was used in Flow cytometry/Cell sorting to show that the expression timing of GATA-2 and CCAAT enhancer-binding protein alpha can differentially control their lineage commitment.
Wed Nov 01 00:00:00 EST 2006
Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis.
The American journal of pathology
Leithäuser F,Meinhardt-Krajina T,Fink K,Wotschke B,Möller P,Reimann J
Thu Jun 01 00:00:00 EDT 2006
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.
Blood
Growney JD,Shigematsu H,Li Z,Lee BH,Adelsperger J,Rowan R,Curley DP,Kutok JL,Akashi K,Williams IR,Speck NA,Gilliland DG
16-1271 was used in Flow cytometry/Cell sorting to indicate that Runx1 deficiency has markedly different consequences during development compared with adult hematopoiesis.
Fri Jul 15 00:00:00 EDT 2005
A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision.
The Journal of experimental medicine
Benz C,Bleul CC
16-1271 was used in Flow cytometry/Cell sorting to identify a multipotent thymic precursor that maps to the branching point of the T versus B lineage decision.
Mon Jul 04 00:00:00 EDT 2005
Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors.
The EMBO journal
Masuda K,Kubagawa H,Ikawa T,Chen CC,Kakugawa K,Hattori M,Kageyama R,Cooper MD,Minato N,Katsura Y,Kawamoto H
16-1271 was used in Flow cytometry/Cell sorting to study the developmental pathway of T cell progenitors preceding thymic colonisation.
Wed Dec 07 00:00:00 EST 2005
GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1.
Molecular and cellular biology
Kuhl C,Atzberger A,Iborra F,Nieswandt B,Porcher C,Vyas P
16-1271 was used in Magnetic cell separation to demonstrate that distinct GATA1 domains regulate terminal megakaryocyte gene expression leading to platelet release and restrained megakaryocyte growth.
Sat Oct 01 00:00:00 EDT 2005
