Product References
STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.
International journal of molecular sciences
Li N,Wang Y,Wang A,Zhang J,Jia C,Yu C,Song Z,Wang S,Liu L,Yi J,Bao Y,Huang Y,Sun L
Published figure using CD135 (Flt3) monoclonal antibody (Product # 17-1351-82) in Flow Cytometry
Fri Feb 03 00:00:00 EST 2023
STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.
International journal of molecular sciences
Li N,Wang Y,Wang A,Zhang J,Jia C,Yu C,Song Z,Wang S,Liu L,Yi J,Bao Y,Huang Y,Sun L
Published figure using CD135 (Flt3) monoclonal antibody (Product # 17-1351-82) in Flow Cytometry
Fri Feb 03 00:00:00 EST 2023
A Myb enhancer-guided analysis of basophil and mast cell differentiation.
Nature communications
Matsumura T,Totani H,Gunji Y,Fukuda M,Yokomori R,Deng J,Rethnam M,Yang C,Tan TK,Karasawa T,Kario K,Takahashi M,Osato M,Sanda T,Suda T
17-1351-82 was used in Flow Cytometry to identify the Myb -68 enhancer, a regulatory element which marks basophils and mast cells, and show a population of granulocyte-macrophage progenitors with higher potential to differentiate into basophils and mast cells.
Fri Nov 18 00:00:00 EST 2022
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.
The Journal of experimental medicine
Ho TT,Dellorusso PV,Verovskaya EV,Bakker ST,Flach J,Smith LK,Ventura PB,Lansinger OM,Hérault A,Zhang SY,Kang YA,Mitchell CA,Villeda SA,Passegué E
Published figure using CD135 (Flt3) monoclonal antibody (Product # 17-1351-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate.
Frontiers in cell and developmental biology
Tang W,He J,Huang T,Bai Z,Wang C,Wang H,Yang R,Ni Y,Hou J,Wang J,Zhou J,Yao Y,Gong Y,Hou S,Liu B,Lan Y
17-1351-82 was used in Flow cytometry/Cell sorting to develop an Hlf-tdTomato reporter mouse model and detected Hlf-tdTomato expression exclusively in the hematopoietic cells including part of the immunophenotypic CD45- and CD45+ pre-HSCs in the embryonic day (E) 10.5 AGM region.
Fri Oct 01 00:00:00 EDT 2021
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD135 (Flt3) monoclonal antibody (Product # 17-1351-82) in Flow Cytometry
Mon Mar 02 00:00:00 EST 2020
SRC-3 Functions as a Coactivator of T-bet by Regulating the Maturation and Antitumor Activity of Natural Killer Cells.
Cancer immunology research
Hu M,Lu Y,Qi Y,Zhang Z,Wang S,Xu Y,Chen F,Tang Y,Chen S,Chen M,Du C,Shen M,Wang F,Su Y,Deng Y,Wang J
17-1351-82 was used in Flow Cytometry to study the role of SRC-3 as a coactivator of T-bet in natural killer-cell biology and indicate that targeting SRC-3 may be a promising strategy to increase the tumor surveillance function of natural killer cells.
Tue Sep 01 00:00:00 EDT 2020
Anti-FLT3 nanoparticles for acute myeloid leukemia: Preclinical pharmacology and pharmacokinetics.
Journal of controlled release : official journal of the Controlled Release Society
Park M,Vaikari VP,Lam AT,Zhang Y,MacKay JA,Alachkar H
17-1351-82 was used in Flow cytometry/Cell sorting to conclude that α-FLT3-A192 fusions appear to be a viable new modality for targeting FLT3 in AML and warrant further preclinical development to bring it into the clinic.
Mon Aug 10 00:00:00 EDT 2020
Zinc finger and BTB domain-containing protein 46 is essential for survival and proliferation of acute myeloid leukemia cell line but dispensable for normal hematopoiesis.
Chinese medical journal
Liu YY,Xiao FF,Yang BJ,Li X,Xu SN,Chen ZW,Li P,Huang YX,Fu XM,Huang XQ,Zheng GL,Chen JP,Hou Y
Published figure using CD135 (Flt3) monoclonal antibody (Product # 17-1351-82) in Flow Cytometry
Mon Jul 20 00:00:00 EDT 2020
The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.
Nature communications
Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ
Published figure using CD135 (Flt3) monoclonal antibody (Product # 17-1351-82) in Flow Cytometry
Thu Sep 17 00:00:00 EDT 2020
Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics.
eLife
Ricci B,Tycksen E,Celik H,Belle JI,Fontana F,Civitelli R,Faccio R
17-1351 was used in Flow cytometry/Cell sorting to find Osx transcript and Osx protein expression early during hematopoiesis, in subsets of hematopoietic stem cells and multipotent progenitor populations.
Wed Aug 05 00:00:00 EDT 2020
An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials.
Immunity
Xu W,Cherrier DE,Chea S,Vosshenrich C,Serafini N,Petit M,Liu P,Golub R,Di Santo JP
Published figure using CD135 (Flt3) monoclonal antibody (Product # 17-1351-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow.
Immunity
Walker JA,Clark PA,Crisp A,Barlow JL,Szeto A,Ferreira ACF,Rana BMJ,Jolin HE,Rodriguez-Rodriguez N,Sivasubramaniam M,Pannell R,Cruickshank J,Daly M,Haim-Vilmovsky L,Teichmann SA,McKenzie ANJ
Published figure using CD135 (Flt3) monoclonal antibody (Product # 17-1351-82) in Flow Cytometry
Tue Jul 16 00:00:00 EDT 2019
Improving the Accuracy of Flow Cytometric Assessment of Mitochondrial Membrane Potential in Hematopoietic Stem and Progenitor Cells Through the Inhibition of Efflux Pumps.
Journal of visualized experiments : JoVE
Morganti C,Bonora M,Ito K
Published figure using CD135 (Flt3) monoclonal antibody (Product # 17-1351-82) in Flow Cytometry
Tue Jul 30 00:00:00 EDT 2019
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment.
Cell stem cell
Yamamoto R,Wilkinson AC,Ooehara J,Lan X,Lai CY,Nakauchi Y,Pritchard JK,Nakauchi H
17-1351 was used in Flow cytometry/Cell sorting to determine the age-related functional changes to the haematopoietic stem cell compartment.
Thu Apr 05 00:00:00 EDT 2018
The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development.
Immunity
Miyazaki M,Miyazaki K,Chen K,Jin Y,Turner J,Moore AJ,Saito R,Yoshida K,Ogawa S,Rodewald HR,Lin YC,Kawamoto H,Murre C
17-1351 was used in Flow cytometry/Cell sorting to propose that the E-Id protein axis specifies innate and adaptive lymphoid cell fate.
Tue May 16 00:00:00 EDT 2017
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.
Nature immunology
Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT
17-1351 was used in Flow cytometry/Cell sorting to examine the significance of ubiquitin signalling in coordinating RNA processing by Toll-like receptor pathways during an immune response and in premalignant haematologic diseases.
Wed Feb 01 00:00:00 EST 2017
MLL-AF9- and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C.
The Journal of clinical investigation
Zhu N,Chen M,Eng R,DeJong J,Sinha AU,Rahnamay NF,Koche R,Al-Shahrour F,Minehart JC,Chen CW,Deshpande AJ,Xu H,Chu SH,Ebert BL,Roeder RG,Armstrong SA
17-1351 was used in Flow cytometry/Cell sorting to show that loss of JMJD1C substantially decreased LSC frequency and caused differentiation of MLL-AF9- and homeobox A9-driven leukemias.
Tue Mar 01 00:00:00 EST 2016
PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia.
The Journal of clinical investigation
Cole CB,Verdoni AM,Ketkar S,Leight ER,Russler-Germain DA,Lamprecht TL,Demeter RT,Magrini V,Ley TJ
17-1351 was used in Flow cytometry/Cell sorting to suggest that PML-RARA requires DNMT3A to initiate acute promyelocytic leukemia in mice.
Fri Jan 01 00:00:00 EST 2016
Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation.
The Journal of clinical investigation
Li J,Razumilava N,Gores GJ,Walters S,Mizuochi T,Mourya R,Bessho K,Wang YH,Glaser SS,Shivakumar P,Bezerra JA
17-1351 was used in Flow cytometry/Cell sorting to demonstrate the role of the Th2-promoting cytokine, IL-33, in cholangiocyte proliferation.
Tue Jul 01 00:00:00 EDT 2014
Eosinophils regulate peripheral B cell numbers in both mice and humans.
Journal of immunology (Baltimore, Md. : 1950)
Wong TW,Doyle AD,Lee JJ,Jelinek DF
17-1351 was used in Flow cytometry/Cell sorting to assess the effect of eosinophils on B cell survival, proliferation, and Ig secretion.
Tue Apr 15 00:00:00 EDT 2014
Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation.
Molecular and cellular biology
Siu KT,Xu Y,Swartz KL,Bhattacharyya M,Gurbuxani S,Hua Y,Minella AC
17-1351 was used in Flow cytometry/Cell sorting to investigate the contribution of individual substrate ubiquitination pathways to hematopoietic stem cell homeostasis, showing that impaired Fbw7-mediated cyclin E regulation leads to chromosome instability.
Mon Sep 01 00:00:00 EDT 2014
Usp16 contributes to somatic stem-cell defects in Down's syndrome.
Nature
Adorno M,Sikandar S,Mitra SS,Kuo A,Nicolis Di Robilant B,Haro-Acosta V,Ouadah Y,Quarta M,Rodriguez J,Qian D,Reddy VM,Cheshier S,Garner CC,Clarke MF
17-1351 was used in Flow cytometry/Cell sorting to demonstrate a role for USP16 in antagonising the self-renewal and senescence pathways in Down's syndrome.
Thu Sep 19 00:00:00 EDT 2013