Product References
Distinct niche structures and intrinsic programs of fallopian tube and ovarian surface epithelial cells.
iScience
Qin G,Park ES,Chen X,Han S,Xiang D,Ren F,Liu G,Chen H,Yuan GC,Li Z
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri Jan 20 00:00:00 EST 2023
Resource: A Cellular Developmental Taxonomy of the Bone Marrow Mesenchymal Stem Cell Population in Mice.
HemaSphere
Pisterzi P,Chen L,van Dijk C,Wevers MJW,Bindels EJM,Raaijmakers MHGP
17-1401-81 was used in Flow cytometry/Cell sorting to delineate the cellularheterogeneity of this MSC-enriched population throughout development.
Wed Feb 01 00:00:00 EST 2023
Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas.
Cell discovery
Zhao H,Huang X,Liu Z,Lai L,Sun R,Shen R,Li Y,He L,Pu W,Lv Z,Li Y,Han X,Liu X,Zhou B
17-1401-81 was used in Flow cytometry/Cell sorting to suggest that the lineage transdifferentiation happens between acinar cells and ductal cells in the pancreatic exocrine glands under specific conditions.
Tue Jan 03 00:00:00 EST 2023
Hematopoietic Cell Autonomous Disruption of Hematopoiesis in a Germline Loss-of-function Mouse Model of RUNX1-FPD.
HemaSphere
Ernst MPT,Pronk E,van Dijk C,van Strien PMH,van Tienhoven TVD,Wevers MJW,Sanders MA,Bindels EMJ,Speck NA,Raaijmakers MHGP
17-1401-81 was used in Flow cytometry/Cell sorting to study mice harboring a germline hypomorphic mutation of one Runx1 allele with a loss-of-function mutation in the other Runx1 allele (Runx1 L148A/- mice), which display many hematologic characteristics found in human RUNX1-FPD patients.
Wed Feb 01 00:00:00 EST 2023
The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency.
Nature communications
Athanasouli P,Balli M,De Jaime-Soguero A,Boel A,Papanikolaou S,van der Veer BK,Janiszewski A,Vanhessche T,Francis A,El Laithy Y,Nigro AL,Aulicino F,Koh KP,Pasque V,Cosma MP,Verfaillie C,Zwijsen A,Heindryckx B,Nikolaou C,Lluis F
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri Mar 03 00:00:00 EST 2023
An estrogen-sensitive fibroblast population drives abdominal muscle fibrosis in an inguinal hernia mouse model.
JCI insight
Potluri T,Taylor MJ,Stulberg JJ,Lieber RL,Zhao H,Bulun SE
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Apr 19 00:00:00 EDT 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Jul 26 00:00:00 EDT 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Jul 26 00:00:00 EDT 2022
PEAR1 regulates expansion of activated fibroblasts and deposition of extracellular matrix in pulmonary fibrosis.
Nature communications
Geng Y,Li L,Yan J,Liu K,Yang A,Zhang L,Shen Y,Gao H,Wu X,Noth I,Huang Y,Liu J,Fan X
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Sat Nov 19 00:00:00 EST 2022
Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function.
Nature communications
Wang Y,Elsherbiny A,Kessler L,Cordero J,Shi H,Serke H,Lityagina O,Trogisch FA,Mohammadi MM,El-Battrawy I,Backs J,Wieland T,Heineke J,Dobreva G
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri Nov 04 00:00:00 EDT 2022
DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal.
Nature communications
Cattaneo P,Hayes MGB,Baumgarten N,Hecker D,Peruzzo S,Aslan GS,Kunderfranco P,Larcher V,Zhang L,Contu R,Fonseca G,Spinozzi S,Chen J,Condorelli G,Dimmeler S,Schulz MH,Heinz S,Guimarães-Camboa N,Evans SM
17-1401-81 was used in Flow cytometry/Cell sorting to reveal that H3K79me2 regulates highly specific transcriptional networks during embryonic cardiogenesis and postnatal cardiomyocyte cell cycle withdrawal.
Fri Dec 02 00:00:00 EST 2022
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.
Nature communications
Qi M,Xia Y,Wu Y,Zhang Z,Wang X,Lu L,Dai C,Song Y,Xu K,Ji W,Zhan L
17-1401-81 was used in Flow Cytometry to demonstrate that Lin28B promotes lung metastasis of breast cancer by building an immune-suppressive pre-metastatic niche.
Wed Feb 16 00:00:00 EST 2022
The microbiota regulates hematopoietic stem cell fate decisions by controlling iron availability in bone marrow.
Cell stem cell
Zhang D,Gao X,Li H,Borger DK,Wei Q,Yang E,Xu C,Pinho S,Frenette PS
17-1401-81 was used in Flow cytometry/Cell sorting to reveal an intricate interplay between the microbiota, macrophages, and iron, and their essential roles in regulating critical HSC fate decisions under stress.
Thu Feb 03 00:00:00 EST 2022
Hypoxia promotes osteogenesis by facilitating acetyl-CoA-mediated mitochondrial-nuclear communication.
The EMBO journal
Pouikli A,Maleszewska M,Parekh S,Yang M,Nikopoulou C,Bonfiglio JJ,Mylonas C,Sandoval T,Schumacher AL,Hinze Y,Matic I,Frezza C,Tessarz P
17-1401-81 was used in Flow Cytometry to study the impact of normoxia on mitochondrial-nuclear communication during stem cell differentiation.
Thu Dec 01 00:00:00 EST 2022
Overexpression of Wild-Type ACVR1 in Fibrodysplasia Ossificans Progressiva Mice Rescues Perinatal Lethality and Inhibits Heterotopic Ossification.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Yamamoto M,Stoessel SJ,Yamamoto S,Goldhamer DJ
17-1401-81 was used in Western Blot to investigate the impact of overexpressing human wild-type ACVR1 in a genetic mouse model of Fibrodysplasia Ossificans Progressiva (FOP).
Tue Nov 01 00:00:00 EDT 2022
Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction.
Cell stem cell
Janbandhu V,Tallapragada V,Patrick R,Li Y,Abeygunawardena D,Humphreys DT,Martin EMMA,Ward AO,Contreras O,Farbehi N,Yao E,Du J,Dunwoodie SL,Bursac N,Harvey RP
17-1401-81 was used in Flow cytometry/Cell sorting to report that cardiac fibroblasts (CFs) and mesenchymal progenitors are more hypoxic than other cardiac interstitial populations, express more hypoxia-inducible factor 1α (HIF-1α), and exhibit increased glycolytic metabolism.
Thu Feb 03 00:00:00 EST 2022
Placental endocrine function shapes cerebellar development and social behavior.
Nature neuroscience
Vacher CM,Lacaille H,O'Reilly JJ,Salzbank J,Bakalar D,Sebaoui S,Liere P,Clarkson-Paredes C,Sasaki T,Sathyanesan A,Kratimenos P,Ellegood J,Lerch JP,Imamura Y,Popratiloff A,Hashimoto-Torii K,Gallo V,Schumacher M,Penn AA
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Immunohistochemistry
Fri Oct 01 00:00:00 EDT 2021
Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function.
Cell stem cell
Allan KC,Hu LR,Scavuzzo MA,Morton AR,Gevorgyan AS,Cohn EF,Clayton BLL,Bederman IR,Hung S,Bartels CF,Madhavan M,Tesar PJ
17-1401-81 was used in Flow Cytometry to demonstrate that HIF1a activates non-canonical targets to impair generation of oligodendrocytes from oligodendrocyte progenitors.
Thu Feb 04 00:00:00 EST 2021
Tmem100- and Acta2-Lineage Cells Contribute to Implant Osseointegration in a Mouse Model.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Vesprey A,Suh ES,Göz Aytürk D,Yang X,Rogers M,Sosa B,Niu Y,Kalajzic I,Ivashkiv LB,Bostrom MP,Ayturk UM
17-1401-81 was used in Flow cytometry/Cell sorting to indicate that PαS cells are mobilized to repair bone tissue and participate in implant osseointegration after surgery.
Sat May 01 00:00:00 EDT 2021
IGF1R controls mechanosignaling in myofibroblasts required for pulmonary alveologenesis.
JCI insight
He H,Snowball J,Sun F,Na CL,Whitsett JA
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Mon Mar 22 00:00:00 EDT 2021
Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer.
Nature communications
Nishina T,Deguchi Y,Ohshima D,Takeda W,Ohtsuka M,Shichino S,Ueha S,Yamazaki S,Kawauchi M,Nakamura E,Nishiyama C,Kojima Y,Adachi-Akahane S,Hasegawa M,Nakayama M,Oshima M,Yagita H,Shibuya K,Mikami T,Inohara N,Matsushima K,Tada N,Nakano H
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri Apr 16 00:00:00 EDT 2021
Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype.
Cell reports
Ma S,McGuire MH,Mangala LS,Lee S,Stur E,Hu W,Bayraktar E,Villar-Prados A,Ivan C,Wu SY,Yokoi A,Dasari SK,Jennings NB,Liu J,Lopez-Berestein G,Ram P,Sood AK
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Feb 09 00:00:00 EST 2021
Extracellular vesicles synchronize cellular phenotypes of differentiating cells.
Journal of extracellular vesicles
Minakawa T,Matoba T,Ishidate F,Fujiwara TK,Takehana S,Tabata Y,Yamashita JK
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Wed Sep 01 00:00:00 EDT 2021
Mesothelial cells are not a source of adipocytes in mice.
Cell reports
Westcott GP,Emont MP,Li J,Jacobs C,Tsai L,Rosen ED
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Jul 13 00:00:00 EDT 2021
Fascin inhibitor increases intratumoral dendritic cell activation and anti-cancer immunity.
Cell reports
Wang Y,Song M,Liu M,Zhang G,Zhang X,Li MO,Ma X,Zhang JJ,Huang XY
17-1401-81 was used in Flow Cytometry to investigate the effects of fascin blockade in anti-tumor immune responses in syngeneic mouse models of various cancers.
Tue Apr 06 00:00:00 EDT 2021
SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors.
Cell death & disease
Giuliani G,Vumbaca S,Fuoco C,Gargioli C,Giorda E,Massacci G,Palma A,Reggio A,Riccio F,Rosina M,Vinci M,Castagnoli L,Cesareni G
17-1401 was used in Flow cytometry/Cell sorting to investigate the impact of heterogeneity in skeletal muscle fibro/adipogenic progenitors (FAPs) isolated from an animal model of Duchenne muscular dystrophy (DMD), the mdx mouse.
Mon Jan 25 00:00:00 EST 2021
Heterogeneity of murine periosteum progenitors involved in fracture healing.
eLife
Matthews BG,Novak S,Sbrana FV,Funnell JL,Cao Y,Buckels EJ,Grcevic D,Kalajzic I
17-1401-81 was used in Flow Cytometry to demonstrate that the periosteum is highly enriched with skeletal progenitor cells, and there is heterogeneity in the populations of cells that contribute to mature lineages during periosteal fracture healing.
Tue Feb 09 00:00:00 EST 2021
Phosphate restriction impairs mTORC1 signaling leading to increased bone marrow adipose tissue and decreased bone in growing mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Ko FC,Kobelski MM,Zhang W,Grenga GM,Martins JS,Demay MB
17-1401-81 was used in Flow cytometry/Cell sorting to elucidate that acute phosphate restriction leads to decreased bone and increased BMAT by impairing mTORC1 signaling in osterix-expressing cells.
Sun Aug 01 00:00:00 EDT 2021
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
eLife
Ambrosi TH,Sinha R,Steininger HM,Hoover MY,Murphy MP,Koepke LS,Wang Y,Lu WJ,Morri M,Neff NF,Weissman IL,Longaker MT,Chan CK
17-1401-81 was used in Flow Cytometry to address previously unappreciated shortcomings of SSC research.
Mon Jul 19 00:00:00 EDT 2021
FACS Enrichment of Total Interstitial Cells and Fibroblasts from Adult Mouse Ventricles.
Bio-protocol
Farbehi N,Janbandhu V,Nordon RE,Harvey RP
17-1401-81 was used in Flow cytometry/Cell sorting to describe the FACS (Fluorescent Activated Cell Sorting)-based method used in that study for isolation of two cardiac cell fractions from adult mouse ventricles: the total interstitial cell population (TIP; non-cardiomyocytes) and enriched (Pdgfra-GFP+) cardiac fibroblasts.
Thu May 20 00:00:00 EDT 2021
Hypoxia depletes contaminating CD45+ hematopoietic cells from murine bone marrow stromal cell (BMSC) cultures: Methods for BMSC culture purification.
Stem cell research
Guo W,Spiller KV,Tang J,Karner CM,Hilton MJ,Wu C
17-1401-81 was used in Flow cytometry/Cell sorting to demonstrate a simple and reliable method exploiting the divergent biological response of hematopoietic and stromal cells to hypoxia to significantly increase the PDGFR α+ stromal cell population in murine BMSC cultures.
Sat May 01 00:00:00 EDT 2021
Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression.
Developmental cell
Wei Q,Nakahara F,Asada N,Zhang D,Gao X,Xu C,Alfieri A,Brodin NP,Zimmerman SE,Mar JC,Guha C,Guo W,Frenette PS
17-1401-81 was used in Flow Cytometry to conclude that SNAI2 is a critical regulator of the transcriptional network maintaining MSPCs by the suppression of osteopontin expression.
Mon Jun 08 00:00:00 EDT 2020
Increased prostaglandin-D2 in male STAT3-deficient hearts shifts cardiac progenitor cells from endothelial to white adipocyte differentiation.
PLoS biology
Stelling E,Ricke-Hoch M,Erschow S,Hoffmann S,Bergmann AK,Heimerl M,Pietzsch S,Battmer K,Haase A,Stapel B,Scherr M,Balligand JL,Binah O,Hilfiker-Kleiner D
17-1401-81 was used in Flow Cytometry to conclude that cardiomyocyte STAT3 deficiency leads to age-related and sex-specific cardiac remodeling and failure in part due to sex-specific alterations in PGD2 secretion and subsequent epigenetic impairment of the differentiation potential of CPC.
Tue Dec 01 00:00:00 EST 2020
Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration.
Life science alliance
Reggio A,Rosina M,Krahmer N,Palma A,Petrilli LL,Maiolatesi G,Massacci G,Salvatori I,Valle C,Testa S,Gargioli C,Fuoco C,Castagnoli L,Cesareni G,Sacco F
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2020
Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Cell reports
Dokoshi T,Zhang LJ,Li F,Nakatsuji T,Butcher A,Yoshida H,Shimoda M,Okada Y,Gallo RL
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Jan 07 00:00:00 EST 2020
Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner.
Cell reports
Santini MP,Malide D,Hoffman G,Pandey G,D'Escamard V,Nomura-Kitabayashi A,Rovira I,Kataoka H,Ochando J,Harvey RP,Finkel T,Kovacic JC
17-1401 was used in Flow cytometry/Cell sorting to support a context-dependent "yin-yang" biology of tissue-resident mesenchymal progenitor cells, which possess an innate ability to limit injury expansion while also promoting fibrosis in an unfavorable environment.
Tue Jan 14 00:00:00 EST 2020
Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner.
Cell reports
Santini MP,Malide D,Hoffman G,Pandey G,D'Escamard V,Nomura-Kitabayashi A,Rovira I,Kataoka H,Ochando J,Harvey RP,Finkel T,Kovacic JC
17-1401 was used in Flow cytometry/Cell sorting to support a context-dependent "yin-yang" biology of tissue-resident mesenchymal progenitor cells, which possess an innate ability to limit injury expansion while also promoting fibrosis in an unfavorable environment.
Tue Jan 14 00:00:00 EST 2020
Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis.
JCI insight
Redente EF,Chakraborty S,Sajuthi S,Black BP,Edelman BL,Seibold MA,Riches DW
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Dec 08 00:00:00 EST 2020
Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice.
Nature communications
Wang S,Cao S,Arhatte M,Li D,Shi Y,Kurz S,Hu J,Wang L,Shao J,Atzberger A,Wang Z,Wang C,Zang W,Fleming I,Wettschureck N,Honoré E,Offermanns S
17-1401 was used in Flow cytometry/Cell sorting to study the mechanosensitive cationic channel Piezo1 and its mediation of diet-induced adipogenesis.
Fri May 08 00:00:00 EDT 2020
Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice.
Nature communications
Wang S,Cao S,Arhatte M,Li D,Shi Y,Kurz S,Hu J,Wang L,Shao J,Atzberger A,Wang Z,Wang C,Zang W,Fleming I,Wettschureck N,Honoré E,Offermanns S
17-1401 was used in Flow cytometry/Cell sorting to study the mechanosensitive cationic channel Piezo1 and its mediation of diet-induced adipogenesis.
Fri May 08 00:00:00 EDT 2020
Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells.
PloS one
Falero-Perez J,Sheibani N,Sorenson CM
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri Jul 31 00:00:00 EDT 2020
Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age.
JCI insight
Wu R,Ma F,Tosevska A,Farrell C,Pellegrini M,Deb A
17-1401 was used in Flow cytometry/Cell sorting to demonstrated that more than 50% of cardiac fibroblasts were actively proliferating in the first day of postnatal life.
Thu Dec 17 00:00:00 EST 2020
Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age.
JCI insight
Wu R,Ma F,Tosevska A,Farrell C,Pellegrini M,Deb A
17-1401 was used in Flow cytometry/Cell sorting to demonstrated that more than 50% of cardiac fibroblasts were actively proliferating in the first day of postnatal life.
Thu Dec 17 00:00:00 EST 2020
Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.
Cell & bioscience
Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2022
Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation.
Nature communications
Azazmeh N,Assouline B,Winter E,Ruppo S,Nevo Y,Maly A,Meir K,Witkiewicz AK,Cohen J,Rizou SV,Pikarsky E,Luxenburg C,Gorgoulis VG,Ben-Porath I
17-1401 was used in Flow cytometry/Cell sorting to investigate the effect of prolonged expression of transgenic p16INK4a in the mouse epidermis and the pathways involved in this effect.
Mon Jun 01 00:00:00 EDT 2020
Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs.
Nature communications
Pein M,Insua-Rodríguez J,Hongu T,Riedel A,Meier J,Wiedmann L,Decker K,Essers MAG,Sinn HP,Spaich S,Sütterlin M,Schneeweiss A,Trumpp A,Oskarsson T
17-1401-81 was used in Flow Cytometry to show that disseminated breast cancer cells evoke phenotypic changes in lung fibroblasts, forming a supportive metastatic niche.
Fri Mar 20 00:00:00 EDT 2020
m6A RNA methylation impacts fate choices during skin morphogenesis.
eLife
Xi L,Carroll T,Matos I,Luo JD,Polak L,Pasolli HA,Jaffrey SR,Fuchs E
17-1401 was used in Flow cytometry/Cell sorting to study mouse skin embryogenesis to tackle m6A's functions and physiological importance.
Wed Aug 26 00:00:00 EDT 2020
Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data.
Genome biology
Patrick R,Humphreys DT,Janbandhu V,Oshlack A,Ho JWK,Harvey RP,Lo KK
17-1401 was used in Flow cytometry/Cell sorting to present a computational pipeline, Sierra, that readily detects differential transcript usage from data generated by commonly used polyA-captured scRNA-seq technology.
Wed Jul 08 00:00:00 EDT 2020
Arterial Sca1+ Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration.
Cell stem cell
Tang J,Wang H,Huang X,Li F,Zhu H,Li Y,He L,Zhang H,Pu W,Liu K,Zhao H,Bentzon JF,Yu Y,Ji Y,Nie Y,Tian X,Zhang L,Gao D,Zhou B
17-1401 was used in Flow cytometry/Cell sorting to perform cell fate mapping and single-cell RNA sequencing to identify Sca1+ VSCs in the adventitial layer of artery walls.
Thu Jan 02 00:00:00 EST 2020
Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells.
Nature cell biology
Nakahara F,Borger DK,Wei Q,Pinho S,Maryanovich M,Zahalka AH,Suzuki M,Cruz CD,Wang Z,Xu C,Boulais PE,Ma'ayan A,Greally JM,Frenette PS
17-1401-81 was used in Flow Cytometry to provide insight into the transcriptional regulation of the niche with implications for stem cell-based therapies.
Wed May 01 00:00:00 EDT 2019
Identification of Functionally Distinct Mx1+αSMA+ Periosteal Skeletal Stem Cells.
Cell stem cell
Ortinau LC,Wang H,Lei K,Deveza L,Jeong Y,Hara Y,Grafe I,Rosenfeld SB,Lee D,Lee B,Scadden DT,Park D
17-1401 was used in Flow cytometry/Cell sorting to report animal models that selectively and durably label postnatal Mx1+αSMA+ periosteal stem cells (P-SSCs) and establish that P-SSCs are a long-term repopulating, functionally distinct SSC subset responsible for lifelong generation of periosteal osteoblasts.
Thu Dec 05 00:00:00 EST 2019
PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment.
PLoS pathogens
Naipauer J,Rosario S,Gupta S,Premer C,Méndez-Solís O,Schlesinger M,Ponzinibbio V,Jain V,Gay L,Renne R,Chan HL,Morey L,Salyakina D,Abba M,Williams S,Hare JM,Goldschmidt-Clermont PJ,Mesri EA
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2019
Transforming Growth Factor β-Activated Kinase 1 Regulates Mesenchymal Stem Cell Proliferation Through Stabilization of Yap1/Taz Proteins.
Stem cells (Dayton, Ohio)
Onodera Y,Teramura T,Takehara T,Fukuda K
17-1401 was used in Flow cytometry/Cell sorting to reveal a novel pathway controlling bone marrow-derived mesenchymal stem cells (BMMSC) proliferation and suggests a useful method to improve the therapeutic effect of BMMSC transplantation.
Sun Dec 01 00:00:00 EST 2019
Regenerative potential of mouse embryonic stem cell-derived PDGFRα+ cardiac lineage committed cells in infarcted myocardium.
World journal of stem cells
Hong SP,Song S,Lee S,Jo H,Kim HK,Han J,Park JH,Cho SW
17-1401 was used in Flow cytometry/Cell sorting to investigate the regenerative potential of mouse embryonic stem cell-derived platelet-derived growth factor receptor-α+ cardiac lineage-committed cells.
Sat Jan 26 00:00:00 EST 2019
Cross-talk between TGF-β and PDGFRα signaling pathways regulates the fate of stromal fibro-adipogenic progenitors.
Journal of cell science
Contreras O,Cruz-Soca M,Theret M,Soliman H,Tung LW,Groppa E,Rossi FM,Brandan E
17-1401 was used in Flow cytometry/Cell sorting to investigate the role of functional cross-talk between TGF-β and PDGFRα signaling pathways in the fate of fibro-adipogenic progenitors (FAPs).
Wed Oct 09 00:00:00 EDT 2019
Dual lineage tracing identifies intermediate mesenchymal stage for endocardial contribution to fibroblasts, coronary mural cells, and adipocytes.
The Journal of biological chemistry
Huang X,Feng T,Jiang Z,Meng J,Kou S,Lu Z,Chen W,Lin CP,Zhou B,Zhang H
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri May 31 00:00:00 EDT 2019
Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.
International journal of molecular sciences
Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M
17-1401 was used in Flow cytometry/Cell sorting to determine which chemokines are expressed in dystrophic muscles undergoing tissue remodelling.
Tue Mar 05 00:00:00 EST 2019
Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells.
International journal of molecular sciences
Camps J,Grosemans H,Gijsbers R,Maes C,Sampaolesi M
17-1401 was used in Flow cytometry/Cell sorting to determine which chemokines are expressed in dystrophic muscles undergoing tissue remodelling.
Tue Mar 05 00:00:00 EST 2019
Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP.
Cell chemical biology
Allimuthu D,Hubler Z,Najm FJ,Tang H,Bederman I,Seibel W,Tesar PJ,Adams DJ
17-1401 was used in Flow cytometry/Cell sorting to identify enhancers of oligodendrocyte formation.
Thu Apr 18 00:00:00 EDT 2019
Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes.
Nature communications
Diéguez-Hurtado R,Kato K,Giaimo BD,Nieminen-Kelhä M,Arf H,Ferrante F,Bartkuhn M,Zimmermann T,Bixel MG,Eilken HM,Adams S,Borggrefe T,Vajkoczy P,Adams RH
17-1401-81 was used in Flow Cytometry to propose that brain pericytes can acquire deleterious properties that actively enhance vascular lesion formation and promote pathogenic processes.
Thu Jun 27 00:00:00 EDT 2019
Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche.
Nature medicine
Maryanovich M,Zahalka AH,Pierce H,Pinho S,Nakahara F,Asada N,Wei Q,Wang X,Ciero P,Xu J,Leftin A,Frenette PS
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri Jun 01 00:00:00 EDT 2018
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination.
Nature
Hubler Z,Allimuthu D,Bederman I,Elitt MS,Madhavan M,Allan KC,Shick HE,Garrison E,T Karl M,Factor DC,Nevin ZS,Sax JL,Thompson MA,Fedorov Y,Jin J,Wilson WK,Giera M,Bracher F,Miller RH,Tesar PJ,Adams DJ
17-1401 was used in Flow cytometry/Cell sorting to identify small molecules that stimulate the formation of oligodendrocytes from oligodendrocyte progenitor cells and functionally enhance remyelination in vivo.
Wed Aug 01 00:00:00 EDT 2018
Early lineage segregation of multipotent embryonic mammary gland progenitors.
Nature cell biology
Wuidart A,Sifrim A,Fioramonti M,Matsumura S,Brisebarre A,Brown D,Centonze A,Dannau A,Dubois C,Van Keymeulen A,Voet T,Blanpain C
17-1401 was used in Flow cytometry/Cell sorting to study the timing and mechanisms mediating early lineage segregation of multipotent progenitors during mammary gland development.
Fri Jun 01 00:00:00 EDT 2018
Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations.
The Journal of investigative dermatology
Philippeos C,Telerman SB,Oulès B,Pisco AO,Shaw TJ,Elgueta R,Lombardi G,Driskell RR,Soldin M,Lynch MD,Watt FM
17-1401 was used in Flow cytometry/Cell sorting to suggest that ex vivo expansion or in vivo ablation of specific fibroblast subpopulations may have therapeutic applications in wound healing and diseases characterized by excessive fibrosis.
Sun Apr 01 00:00:00 EDT 2018
Cardiac Nestin+ Cells Derived from Early Stage of Dilated Cardiomyopathy Enhanced the Survival of the Doxorubicin-Injured Cardiac Muscle HL-1 Cells.
International heart journal
Xie D,Liao Y,Wu B,Chen Y,Lin W,Lu D,Gao S,Zhu S,Peng C,Jiang MH
17-1401 was used in Flow cytometry/Cell sorting to show that the loss of Nestin+ cells might be an etiology to DCM pathogenesis, and these cells could be a promising candidate cell source for study and treatment of DCM patients.
Mon Feb 05 00:00:00 EST 2018
SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells.
Nature communications
Chagraoui H,Kristiansen MS,Ruiz JP,Serra-Barros A,Richter J,Hall-Ponselé E,Gray N,Waithe D,Clark K,Hublitz P,Repapi E,Otto G,Sopp P,Taylor S,Thongjuea S,Vyas P,Porcher C
17-1401 was used in Flow cytometry/Cell sorting to investigate how mesoderm specifies into blood-fated cells.
Tue Dec 18 00:00:00 EST 2018
FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors.
Stem cell reports
Yoon C,Song H,Yin T,Bausch-Fluck D,Frei AP,Kattman S,Dubois N,Witty AD,Hewel JA,Guo H,Emili A,Wollscheid B,Keller G,Zandstra PW
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Jan 09 00:00:00 EST 2018
Pdgfra marks a cellular lineage with distinct contributions to myofibroblasts in lung maturation and injury response.
eLife
Li R,Bernau K,Sandbo N,Gu J,Preissl S,Sun X
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Sep 04 00:00:00 EDT 2018
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias.
Nature communications
Chaudhury S,O'Connor C,Cañete A,Bittencourt-Silvestre J,Sarrou E,Prendergast Á,Choi J,Johnston P,Wells CA,Gibson B,Keeshan K
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Dec 11 00:00:00 EST 2018
Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva.
Nature communications
Lees-Shepard JB,Yamamoto M,Biswas AA,Stoessel SJ,Nicholas SE,Cogswell CA,Devarakonda PM,Schneider MJ,Cummins SM,Legendre NP,Yamamoto S,Kaartinen V,Hunter JW,Goldhamer DJ
17-1401 was used in Flow cytometry/Cell sorting to show that fibro/adipogenic progenitors are major cells-of-origin of heterotopic ossification, in an accurate genetic mouse model of fibrodysplasia ossificans progressiva.
Fri Feb 02 00:00:00 EST 2018
PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration.
International journal of molecular sciences
Dammone G,Karaz S,Lukjanenko L,Winkler C,Sizzano F,Jacot G,Migliavacca E,Palini A,Desvergne B,Gilardi F,Feige JN
17-1401 was used in Flow cytometry/Cell sorting to study muscle regeneration and tissue-resident muscle stem cell function in whole body Pparg null mice generated by epiblast-specific Cre/lox deletion (PpargΔ/Δ).
Fri Jul 13 00:00:00 EDT 2018
Hyaluronidase inhibits reactive adipogenesis and inflammation of colon and skin.
JCI insight
Dokoshi T,Zhang LJ,Nakatsuji T,Adase CA,Sanford JA,Paladini RD,Tanaka H,Fujiya M,Gallo RL
17-1401 was used in Flow cytometry/Cell sorting to suggest hyaluronidase plays an important role in reactive adipogenesis and host defense after injury.
Fri Nov 02 00:00:00 EDT 2018
Pulmonary pericytes regulate lung morphogenesis.
Nature communications
Kato K,Diéguez-Hurtado R,Park DY,Hong SP,Kato-Azuma S,Adams S,Stehling M,Trappmann B,Wrana JL,Koh GY,Adams RH
17-1401 was used in Flow cytometry/Cell sorting to establish that pericytes coordinate the behavior of epithelial and vascular cells during lung morphogenesis.
Fri Jun 22 00:00:00 EDT 2018
HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles.
Scientific reports
Lee D,Taniguchi N,Sato K,Choijookhuu N,Hishikawa Y,Kataoka H,Morinaga H,Lotz M,Chosa E
17-1401 was used in Flow cytometry/Cell sorting to study the role of high-mobility group box 2 in adipogenesis of mesenchymal stem cells and fat infiltration into skeletal muscles.
Mon Jun 25 00:00:00 EDT 2018
Lineage dynamics of murine pancreatic development at single-cell resolution.
Nature communications
Byrnes LE,Wong DM,Subramaniam M,Meyer NP,Gilchrist CL,Knox SM,Tward AD,Ye CJ,Sneddon JB
17-1401 was used in Flow cytometry/Cell sorting to identify the cellular heterogeneity of the developing mesenchyme, and reconstruct potential lineage relationships among the pancreatic mesothelium and mesenchymal cell types.
Tue Sep 25 00:00:00 EDT 2018
Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium.
Cell research
Zhang H,Huang X,Liu K,Tang J,He L,Pu W,Liu Q,Li Y,Tian X,Wang Y,Zhang L,Yu Y,Wang H,Hu R,Wang F,Chen T,Wang QD,Qiao Z,Zhang L,Lui KO,Zhou B
17-1401 was used in Flow cytometry/Cell sorting to examine the origin of the excessive fibroblasts found within endocardial fibroelastosis-like tissues.
Fri Sep 01 00:00:00 EDT 2017
Preexisting endothelial cells mediate cardiac neovascularization after injury.
The Journal of clinical investigation
He L,Huang X,Kanisicak O,Li Y,Wang Y,Li Y,Pu W,Liu Q,Zhang H,Tian X,Zhao H,Liu X,Zhang S,Nie Y,Hu S,Miao X,Wang QD,Wang F,Chen T,Xu Q,Lui KO,Molkentin JD,Zhou B
Tue Aug 01 00:00:00 EDT 2017
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease.
EMBO molecular medicine
Oak P,Pritzke T,Thiel I,Koschlig M,Mous DS,Windhorst A,Jain N,Eickelberg O,Foerster K,Schulze A,Goepel W,Reicherzer T,Ehrhardt H,Rottier RJ,Ahnert P,Gortner L,Desai TJ,Hilgendorff A
17-1401 was used in Blocking experiments to discover attenuated PDGF signalling as a driver of neonatal chronic lung disease and provision of PDGF-A as a protective strategy.
Wed Nov 01 00:00:00 EDT 2017
Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity.
Genes & development
Turrell FK,Kerr EM,Gao M,Thorpe H,Doherty GJ,Cridge J,Shorthouse D,Speed A,Samarajiwa S,Hall BA,Griffiths M,Martins CP
17-1401 was used in Flow cytometry/Cell sorting to show that the potential of p53 targeted therapies is comparable across all p53-deficient genotypes.
Sat Jul 01 00:00:00 EDT 2017
miR-155 induces ROS generation through downregulation of antioxidation-related genes in mesenchymal stem cells.
Aging cell
Onodera Y,Teramura T,Takehara T,Obora K,Mori T,Fukuda K
17-1401 was used in Flow cytometry/Cell sorting to identify miR-155 as an inducer of reactive oxygen species generation in mesenchymal stem cells.
Fri Dec 01 00:00:00 EST 2017
Estrogen modulates mesenchyme-epidermis interactions in the adult nipple.
Development (Cambridge, England)
Wu HJ,Oh JW,Spandau DF,Tholpady S,Diaz J,Schroeder LJ,Offutt CD,Glick AB,Plikus MV,Koyama S,Foley J
17-1401 was used in Flow cytometry/Cell sorting to show that specialized nipple epidermis is maintained by estrogen-induced repression of TGFβ signalling in the local fibroblasts.
Sat Apr 15 00:00:00 EDT 2017
Gli1 identifies osteogenic progenitors for bone formation and fracture repair.
Nature communications
Shi Y,He G,Lee WC,McKenzie JA,Silva MJ,Long F
Mon Dec 11 00:00:00 EST 2017
Insulin fine-tunes self-renewal pathways governing naive pluripotency and extra-embryonic endoderm.
Nature cell biology
Anderson KGV,Hamilton WB,Roske FV,Azad A,Knudsen TE,Canham MA,Forrester LM,Brickman JM
17-1401-81 was used in Flow cytometry/Cell sorting to study the effects of insulin on endoderm differentiation and the self-renewal in pluripotent cells.
Sun Oct 01 00:00:00 EDT 2017
Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells.
Nature communications
Semrau S,Goldmann JE,Soumillon M,Mikkelsen TS,Jaenisch R,van Oudenaarden A
17-1401 was used in Flow cytometry/Cell sorting to analyse the exit from pluripotency and lineage commitment at the single cell level, allowing improved lineage manipulation through timing of differentiation cues.
Mon Oct 23 00:00:00 EDT 2017
PDGFRα+ Cells in Embryonic Stem Cell Cultures Represent the In Vitro Equivalent of the Pre-implantation Primitive Endoderm Precursors.
Stem cell reports
Lo Nigro A,de Jaime-Soguero A,Khoueiry R,Cho DS,Ferlazzo GM,Perini I,Abon Escalona V,Aranguren XL,Chuva de Sousa Lopes SM,Koh KP,Conaldi PG,Hu WS,Zwijsen A,Lluis F,Verfaillie CM
17140181 was used in flow cytometry and immunocytochemistry to show that cultured mouse embryonic stem cells express platelet-derived growth factor receptor alpha heterogeneously
Tue Feb 14 00:00:00 EST 2017
Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice.
Nature medicine
Lukjanenko L,Jung MJ,Hegde N,Perruisseau-Carrier C,Migliavacca E,Rozo M,Karaz S,Jacot G,Schmidt M,Li L,Metairon S,Raymond F,Lee U,Sizzano F,Wilson DH,Dumont NA,Palini A,Fässler R,Steiner P,Descombes P,Rudnicki MA,Fan CM,von Maltzahn J,Feige JN,Bentzinger CF
17140181 was used in flow cytometry to show that the loss of stem cell adhesion to fibronectin is a mechanism of aging
Mon Aug 01 00:00:00 EDT 2016
Fibrinolytic crosstalk with endothelial cells expands murine mesenchymal stromal cells.
Blood
Dhahri D,Sato-Kusubata K,Ohki-Koizumi M,Nishida C,Tashiro Y,Munakata S,Shimazu H,Salama Y,Eiamboonsert S,Nakauchi H,Hattori K,Heissig B
17-1401 was used in Flow cytometry/Cell sorting to show a novel mechanism by which the fibrinolytic system expands PαS-MSCs through a cytokine crosstalk between niche cells.
Thu Aug 25 00:00:00 EDT 2016
Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene.
Circulation research
Lombardi R,Chen SN,Ruggiero A,Gurha P,Czernuszewicz GZ,Willerson JT,Marian AJ
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri Jun 24 00:00:00 EDT 2016
Revisiting Cardiac Cellular Composition.
Circulation research
Pinto AR,Ilinykh A,Ivey MJ,Kuwabara JT,D'Antoni ML,Debuque R,Chandran A,Wang L,Arora K,Rosenthal NA,Tallquist MD
17-1401 was used in Flow cytometry/Cell sorting to examine the relative frequency of cardiac endothelial cells, hematopoietic-derived cells, and fibroblasts in the mouse and human heart.
Fri Feb 05 00:00:00 EST 2016
Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in Mice.
Circulation research
Kaur H,Takefuji M,Ngai CY,Carvalho J,Bayer J,Wietelmann A,Poetsch A,Hoelper S,Conway SJ,Möllmann H,Looso M,Troidl C,Offermanns S,Wettschureck N
17-1401 was used in Flow cytometry/Cell sorting to study the effect of activated cardiac fibroblast ablation on cardiac remodeling.
Fri Jun 10 00:00:00 EDT 2016
Regionally Restricted Hox Function in Adult Bone Marrow Multipotent Mesenchymal Stem/Stromal Cells.
Developmental cell
Rux DR,Song JY,Swinehart IT,Pineault KM,Schlientz AJ,Trulik KG,Goldstein SA,Kozloff KM,Lucas D,Wellik DM
17-1401 was used in Flow cytometry/Cell sorting to demonstrate Hox11 expression exclusively in multipotent mesenchymal stromal cells in the bone marrow of the adult zeugopod.
Mon Dec 19 00:00:00 EST 2016
β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis.
The Journal of investigative dermatology
Mastrogiannaki M,Lichtenberger BM,Reimer A,Collins CA,Driskell RR,Watt FM
17-1401 was used in Flow cytometry/Cell sorting to study how Wnt/β-catenin signalling may control adipogenic cell fate within the lower dermis, which potentially contributes to the pathogenesis of fibrotic skin diseases.
Wed Jun 01 00:00:00 EDT 2016
Genetic lineage tracing defines myofibroblast origin and function in the injured heart.
Nature communications
Kanisicak O,Khalil H,Ivey MJ,Karch J,Maliken BD,Correll RN,Brody MJ,J Lin SC,Aronow BJ,Tallquist MD,Molkentin JD
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri Jul 22 00:00:00 EDT 2016
mTOR inhibition and BMP signaling act synergistically to reduce muscle fibrosis and improve myofiber regeneration.
JCI insight
Agarwal S,Cholok D,Loder S,Li J,Breuler C,Chung MT,Sung HH,Ranganathan K,Habbouche J,Drake J,Peterson J,Priest C,Li S,Mishina Y,Levi B
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Thu Dec 08 00:00:00 EST 2016
Laminin regulates PDGFRβ(+) cell stemness and muscle development.
Nature communications
Yao Y,Norris EH,Mason CE,Strickland S
17-1401 was used in Flow cytometry/Cell sorting to show that laminin has a critical role in the control of PDGFRBeta(+) cell stemness and that PDGFRBeta(+) may be a drug target for treatment of muscular dystrophy.
Tue May 03 00:00:00 EDT 2016
MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model.
eLife
Ogawa Y,Morikawa S,Okano H,Mabuchi Y,Suzuki S,Yaguchi T,Sato Y,Mukai S,Yaguchi S,Inaba T,Okamoto S,Kawakami Y,Tsubota K,Matsuzaki Y,Shimmura S
17-1401 was used in Flow cytometry/Cell sorting to investigate the fibrosis in a scleroderma mouse model which is triggered by antigen mismatched bone marrow stromal/stem cells.
Tue Jan 26 00:00:00 EST 2016
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.
Nature
Najm FJ,Madhavan M,Zaremba A,Shick E,Karl RT,Factor DC,Miller TE,Nevin ZS,Kantor C,Sargent A,Quick KL,Schlatzer DM,Tang H,Papoian R,Brimacombe KR,Shen M,Boxer MB,Jadhav A,Robinson AP,Podojil JR,Miller SD,Miller RH,Tesar PJ
17-1401 was used in Flow cytometry/Cell sorting to study the drug-based modulation of endogenous stem cells which promotes functional remyelination in vivo.
Thu Jun 11 00:00:00 EDT 2015
The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors.
Cell stem cell
Caputo L,Witzel HR,Kolovos P,Cheedipudi S,Looso M,Mylona A,van IJcken WF,Laugwitz KL,Evans SM,Braun T,Soler E,Grosveld F,Dobreva G
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Thu Sep 03 00:00:00 EDT 2015
Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle.
The Journal of clinical investigation
Quattrocelli M,Swinnen M,Giacomazzi G,Camps J,Barthélemy I,Ceccarelli G,Caluwé E,Grosemans H,Thorrez L,Pelizzo G,Muijtjens M,Verfaillie CM,Blot S,Janssens S,Sampaolesi M
17-1401 was used in Flow cytometry/Cell sorting to study the functional regeneration of cardiac and skeletal muscle via mesodermal iPSC-derived progenitor cells.
Tue Dec 01 00:00:00 EST 2015
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
The Journal of experimental medicine
Pallangyo CK,Ziegler PK,Greten FR
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Mon Dec 14 00:00:00 EST 2015
Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2.
EMBO reports
Liu F,Li D,Yu YY,Kang I,Cha MJ,Kim JY,Park C,Watson DK,Wang T,Choi K
17-1401 was used in Flow cytometry/Cell sorting to highlight the critical role that transient ETV2 expression plays in the regulation of hematopoietic and endothelial cell lineage specification and stability.
Fri May 01 00:00:00 EDT 2015
Brg1 modulates enhancer activation in mesoderm lineage commitment.
Development (Cambridge, England)
Alexander JM,Hota SK,He D,Thomas S,Ho L,Pennacchio LA,Bruneau BG
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Wed Apr 15 00:00:00 EDT 2015
FOXF1 inhibits hematopoietic lineage commitment during early mesoderm specification.
Development (Cambridge, England)
Fleury M,Eliades A,Carlsson P,Lacaud G,Kouskoff V
17-1401 was used in Flow cytometry/Cell sorting to investigate the lineage specification of early mesodermal precursors expressing or not the Forkhead transcription factor FOXF1.
Thu Oct 01 00:00:00 EDT 2015
Pretreatment of Mesenchymal Stem Cells Manipulates Their Vasculoprotective Potential While Not Altering Their Homing Within the Injured Gut.
Stem cells (Dayton, Ohio)
Kavanagh DP,Suresh S,Newsome PN,Frampton J,Kalia N
17-1401 was used in Flow cytometry/Cell sorting to demonstrate that MSCs can limit leukocyte recruitment and improve tissue perfusion following intestinal ischemia-reperfusion injury.
Tue Sep 01 00:00:00 EDT 2015
Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro.
Cell transplantation
Nakatsuka R,Matsuoka Y,Uemura Y,Sumide K,Iwaki R,Takahashi M,Fujioka T,Sasaki Y,Sonoda Y
17-1401 was used in Flow cytometry/Cell sorting to demonstrate that prospectively isolated murine PDGFRα and Sca-1 double-positive dental pulp stem cells could support primitive human CD34+ and CD34- hematopoietic stem cells in vitro.
Wed Sep 16 00:00:00 EDT 2015
Alpha-Synuclein Expression in the Oligodendrocyte Lineage: an In Vitro and In Vivo Study Using Rodent and Human Models.
Stem cell reports
Djelloul M,Holmqvist S,Boza-Serrano A,Azevedo C,Yeung MS,Goldwurm S,Frisén J,Deierborg T,Roybon L
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Aug 11 00:00:00 EDT 2015
The Etv2-miR-130a Network Regulates Mesodermal Specification.
Cell reports
Singh BN,Kawakami Y,Akiyama R,Rasmussen TL,Garry MG,Gong W,Das S,Shi X,Koyano-Nakagawa N,Garry DJ
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Nov 03 00:00:00 EST 2015
Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair.
Circulation research
Furtado MB,Costa MW,Pranoto EA,Salimova E,Pinto AR,Lam NT,Park A,Snider P,Chandran A,Harvey RP,Boyd R,Conway SJ,Pearson J,Kaye DM,Rosenthal NA
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri Apr 25 00:00:00 EDT 2014
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis.
The Journal of clinical investigation
Moore-Morris T,Guimarães-Camboa N,Banerjee I,Zambon AC,Kisseleva T,Velayoudon A,Stallcup WB,Gu Y,Dalton ND,Cedenilla M,Gomez-Amaro R,Zhou B,Brenner DA,Peterson KL,Chen J,Evans SM
17-1401 was used in Flow cytometry/Cell sorting to study the the origins of cardiac fibroblasts during development and in fibrosis.
Tue Jul 01 00:00:00 EDT 2014
Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors.
Proceedings of the National Academy of Sciences of the United States of America
Donati G,Proserpio V,Lichtenberger BM,Natsuga K,Sinclair R,Fujiwara H,Watt FM
17-1401 was used in Flow cytometry/Cell sorting to elucidate the mechanisms by which the epidermis can regulate adipogenesis.
Tue Apr 15 00:00:00 EDT 2014
Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors.
Proceedings of the National Academy of Sciences of the United States of America
Donati G,Proserpio V,Lichtenberger BM,Natsuga K,Sinclair R,Fujiwara H,Watt FM
17-1401 was used in Flow cytometry/Cell sorting to elucidate the mechanisms by which the epidermis can regulate adipogenesis.
Tue Apr 15 00:00:00 EDT 2014
Recruitment of bone marrow-derived cells to periodontal tissue defects.
Frontiers in cell and developmental biology
Kimura Y,Komaki M,Iwasaki K,Sata M,Izumi Y,Morita I
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Mon Nov 03 00:00:00 EST 2014
Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma.
PLoS genetics
Kikuchi K,Hettmer S,Aslam MI,Michalek JE,Laub W,Wilky BA,Loeb DM,Rubin BP,Wagers AJ,Keller C
17-1401 was used in Flow cytometry/Cell sorting to show that the regulation of the Pax3:Foxo1a locus has important implications for the way oncogenes are modelled in cancer cells.
Wed Jan 01 00:00:00 EST 2014
Oncostatin M maintains the hematopoietic microenvironment in the bone marrow by modulating adipogenesis and osteogenesis.
PloS one
Sato F,Miyaoka Y,Miyajima A,Tanaka M
17-1401 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying mesenchymal stromal cell differentiation, showing that oncostatin M maintains the hematopoietic microenvironment in the bone marrow.
Wed May 04 00:00:00 EDT 2016
Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
Nature communications
Aksoy I,Giudice V,Delahaye E,Wianny F,Aubry M,Mure M,Chen J,Jauch R,Bogu GK,Nolden T,Himmelbauer H,Xavier Doss M,Sachinidis A,Schulz H,Hummel O,Martinelli P,Hübner N,Stanton LW,Real FX,Bourillot PY,Savatier P
17-1401 was used in Flow cytometry/Cell sorting to study the functional divergence between Klf4 and Klf5 in the inhibition of mouse embryonic stem cell differentiation.
Mon Apr 28 00:00:00 EDT 2014
KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.
Cell stem cell
Goldman O,Han S,Sourisseau M,Dziedzic N,Hamou W,Corneo B,D'Souza S,Sato T,Kotton DN,Bissig KD,Kalir T,Jacobs A,Evans T,Evans MJ,Gouon-Evans V
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Thu Jun 06 00:00:00 EDT 2013
Specification of chondrocytes and cartilage tissues from embryonic stem cells.
Development (Cambridge, England)
Craft AM,Ahmed N,Rockel JS,Baht GS,Alman BA,Kandel RA,Grigoriadis AE,Keller GM
17-1401 was used in Flow cytometry/Cell sorting to establish the developmental program for chondrogenic mesoderm formation from mouse embryonic stem cells.
Sat Jun 01 00:00:00 EDT 2013
Dynamic and nuclear expression of PDGFRα and IGF-1R in alveolar Rhabdomyosarcoma.
Molecular cancer research : MCR
Aslam MI,Hettmer S,Abraham J,Latocha D,Soundararajan A,Huang ET,Goros MW,Michalek JE,Wang S,Mansoor A,Druker BJ,Wagers AJ,Tyner JW,Keller C
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Totipotent embryonic stem cells arise in ground-state culture conditions.
Cell reports
Morgani SM,Canham MA,Nichols J,Sharov AA,Migueles RP,Ko MS,Brickman JM
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Thu Jun 27 00:00:00 EDT 2013
ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells.
Blood
Joo HJ,Choi DK,Lim JS,Park JS,Lee SH,Song S,Shin JH,Lim DS,Kim I,Hwang KC,Koh GY
17-1401 was used in Flow cytometry/Cell sorting to demonstrate a versatile method for obtaining an ample amount of ESC-derived ECs for use in therapeutic neovascularisation.
Thu Sep 27 00:00:00 EDT 2012
ER71 specifies Flk-1+ hemangiogenic mesoderm by inhibiting cardiac mesoderm and Wnt signaling.
Blood
Liu F,Kang I,Park C,Chang LW,Wang W,Lee D,Lim DS,Vittet D,Nerbonne JM,Choi K
17-1401 was used in Flow cytometry/Cell sorting to investigate whether ER71 could modulate the haemangiogenic or cardiogenic outcome of the Flk-1(+) mesoderm.
Thu Apr 05 00:00:00 EDT 2012
Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression.
Stem cells (Dayton, Ohio)
Koyano-Nakagawa N,Kweon J,Iacovino M,Shi X,Rasmussen TL,Borges L,Zirbes KM,Li T,Perlingeiro RC,Kyba M,Garry DJ
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Wed Aug 01 00:00:00 EDT 2012
Origins and properties of dental, thymic, and bone marrow mesenchymal cells and their stem cells.
PloS one
Komada Y,Yamane T,Kadota D,Isono K,Takakura N,Hayashi S,Yamazaki H
17-1401 was used in Flow cytometry/Cell sorting to investigate whether mesechymal cells arise from neural crest or mesoderm, revealing the origins and properties of dental, thymic, and bone marrow mesenchymal cells.
Tue May 14 00:00:00 EDT 2013
Isolation of mouse mesenchymal stem cells on the basis of expression of Sca-1 and PDGFR-α.
Nature protocols
Houlihan DD,Mabuchi Y,Morikawa S,Niibe K,Araki D,Suzuki S,Okano H,Matsuzaki Y
17-1401-81 was used in Flow cytometry/Cell sorting to describe a protocol for the isolation of platelet-derived growth factor receptor α (PDGFR-α) (+) and stem cell antigen 1 (Sca-1) (+) (PαS) mouse mesenchymal stem cells (MSCs) using flow cytometry.
Sat Dec 01 00:00:00 EST 2012
Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells.
Nature methods
Najm FJ,Zaremba A,Caprariello AV,Nayak S,Freundt EC,Scacheri PC,Miller RH,Tesar PJ
17-1401 was used in Flow cytometry/Cell sorting to develop a protocol for the rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells.
Sun Sep 25 00:00:00 EDT 2011
Defining the earliest step of cardiovascular progenitor specification during embryonic stem cell differentiation.
The Journal of cell biology
Bondue A,Tännler S,Chiapparo G,Chabab S,Ramialison M,Paulissen C,Beck B,Harvey R,Blanpain C
17-1401 was used in Flow cytometry/Cell sorting to identify the early MCPs residing at the top of the cellular hierarchy of cardiovascular lineages during ESC differentiation.
Mon Mar 07 00:00:00 EST 2011
ER71 directs mesodermal fate decisions during embryogenesis.
Development (Cambridge, England)
Rasmussen TL,Kweon J,Diekmann MA,Belema-Bedada F,Song Q,Bowlin K,Shi X,Ferdous A,Li T,Kyba M,Metzger JM,Koyano-Nakagawa N,Garry DJ
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2011
Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs.
Stem cells (Dayton, Ohio)
Gill JG,Langer EM,Lindsley RC,Cai M,Murphy TL,Kyba M,Murphy KM
17-1401 was used in Flow cytometry/Cell sorting to investigate the role of Snail and microRNA-200 in regulating epithelial-to-mesenchymal transition and embryonic stem cell differentiation.
Sun May 01 00:00:00 EDT 2011
Hepatoblast-like progenitor cells derived from embryonic stem cells can repopulate livers of mice.
Gastroenterology
Li F,Liu P,Liu C,Xiang D,Deng L,Li W,Wangensteen K,Song J,Ma Y,Hui L,Wei L,Li L,Ding X,Hu Y,He Z,Wang X
17-1401 was used in Flow cytometry/Cell sorting to identify and purify ES cell-derived hepatoblast-like progenitor cells and to explore their capacity for liver repopulation in mice after in vitro expansion.
Wed Dec 01 00:00:00 EST 2010
CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland.
Stem cells (Dayton, Ohio)
LaMarca HL,Visbal AP,Creighton CJ,Liu H,Zhang Y,Behbod F,Rosen JM
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Wed Mar 31 00:00:00 EDT 2010
Ontogeny of stromal organizer cells during lymph node development.
Journal of immunology (Baltimore, Md. : 1950)
Bénézech C,White A,Mader E,Serre K,Parnell S,Pfeffer K,Ware CF,Anderson G,Caamaño JH
17-1401 was used in Immunofluorescence to highlight the importance of the signals and cellular interactions that induce the maturation of stromal cells.
Thu Apr 15 00:00:00 EDT 2010
Ontogeny of stromal organizer cells during lymph node development.
Journal of immunology (Baltimore, Md. : 1950)
Bénézech C,White A,Mader E,Serre K,Parnell S,Pfeffer K,Ware CF,Anderson G,Caamaño JH
17-1401 was used in Immunofluorescence to highlight the importance of the signals and cellular interactions that induce the maturation of stromal cells.
Thu Apr 15 00:00:00 EDT 2010
Bioluminescence imaging of Olig2-neural stem cells reveals improved engraftment in a demyelination mouse model.
Stem cells (Dayton, Ohio)
Sher F,van Dam G,Boddeke E,Copray S
Published figure using CD140a (PDGFRA) monoclonal antibody (Product # 17-1401-81) in Flow Cytometry
Wed Jul 01 00:00:00 EDT 2009
Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Mukouyama YS,Deneen B,Lukaszewicz A,Novitch BG,Wichterle H,Jessell TM,Anderson DJ
Tue Jan 31 00:00:00 EST 2006
Tlx, an orphan nuclear receptor, regulates cell numbers and astrocyte development in the developing retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Miyawaki T,Uemura A,Dezawa M,Yu RT,Ide C,Nishikawa S,Honda Y,Tanabe Y,Tanabe T
Wed Sep 15 00:00:00 EDT 2004
