Product References
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation.
Nature immunology
Rivas MA,Meydan C,Chin CR,Challman MF,Kim D,Bhinder B,Kloetgen A,Viny AD,Teater MR,McNally DR,Doane AS,Béguelin W,Fernández MTC,Shen H,Wang X,Levine RL,Chen Z,Tsirigos A,Elemento O,Mason CE,Melnick AM
Published figure using CD23 monoclonal antibody (Product # 25-0232-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Assessing Lupus-Like Disease in Murine Model Systems.
Current protocols
Lee HY,Celhar T,Fairhurst AM
25-0232-82 was used in Flow Cytometry to evaluate the underlying immunological features of the disease, as a more sensitive strategy to understand the disease itself and the mechanisms of potential novel therapeutics.
Mon Nov 01 00:00:00 EDT 2021
Neonatal Exposure to Commensal-Bacteria-Derived Antigens Directs Polysaccharide-Specific B-1 B Cell Repertoire Development.
Immunity
New JS,Dizon BLP,Fucile CF,Rosenberg AF,Kearney JF,King RG
25-0232-82 was used in Flow Cytometry to show that exposure to microbial antigens in early life determines the clonality of the mature B-1 B cell repertoire and ensuing antibody responses, with implications for vaccination approaches and schedules.
Tue Jul 14 00:00:00 EDT 2020
Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity.
Cancer cell
Yu X,Chan HTC,Fisher H,Penfold CA,Kim J,Inzhelevskaya T,Mockridge CI,French RR,Duriez PJ,Douglas LR,English V,Verbeek JS,White AL,Tews I,Glennie MJ,Cragg MS
Published figure using CD23 monoclonal antibody (Product # 25-0232-82) in Flow Cytometry
Mon Jun 08 00:00:00 EDT 2020
Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells.
The Journal of clinical investigation
Khiew SH,Jain D,Chen J,Yang J,Yin D,Young JS,Dent A,Sciammas R,Alegre ML,Chong AS
25-0232 was used in Flow cytometry/Cell sorting to showed that alloreactive B cells were not deleted but rapidly lost their ability to differentiate into germinal center B cells and secrete donor-specific antibodies., by using a murine model of heart tolerance.
Wed Jul 01 00:00:00 EDT 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
25-0232 was used in Flow cytometry/Cell sorting to uncover a mechanism that controls myeloid regeneration and early lineage decisions in HSCs and could be targeted in LSCs to normalize leukemic myeloid cell production.
Mon Mar 02 00:00:00 EST 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
25-0232 was used in Flow cytometry/Cell sorting to uncover a mechanism that controls myeloid regeneration and early lineage decisions in HSCs and could be targeted in LSCs to normalize leukemic myeloid cell production.
Mon Mar 02 00:00:00 EST 2020
Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production.
The Journal of experimental medicine
Lau A,Avery DT,Jackson K,Lenthall H,Volpi S,Brigden H,Russell AJ,Bier J,Reed JH,Smart JM,Cole T,Choo S,Gray PE,Berglund LJ,Hsu P,Wong M,O'Sullivan M,Boztug K,Meyts I,Uzel G,Notarangelo LD,Brink R,Goodnow CC,Tangye SG,Deenick EK
25-0232-82 was used in Flow Cytometry to understand the role of PI3K signalling in regulating B cells during antibody-mediated autoimmune diseases.
Mon Feb 03 00:00:00 EST 2020
Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production.
The Journal of experimental medicine
Lau A,Avery DT,Jackson K,Lenthall H,Volpi S,Brigden H,Russell AJ,Bier J,Reed JH,Smart JM,Cole T,Choo S,Gray PE,Berglund LJ,Hsu P,Wong M,O'Sullivan M,Boztug K,Meyts I,Uzel G,Notarangelo LD,Brink R,Goodnow CC,Tangye SG,Deenick EK
25-0232-82 was used in Flow Cytometry to understand the role of PI3K signalling in regulating B cells during antibody-mediated autoimmune diseases.
Mon Feb 03 00:00:00 EST 2020
Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling.
The EMBO journal
Fennell LM,Gomez Diaz C,Deszcz L,Kavirayani A,Hoffmann D,Yanagitani K,Schleiffer A,Mechtler K,Hagelkruys A,Penninger J,Ikeda F
25-0232-82 was used in Flow Cytometry to propose that site-specific ubiquitination of HOIP regulates a LUBAC-dependent switch between survival and apoptosis in TNF signaling.
Tue Dec 15 00:00:00 EST 2020
CD83 expression regulates antibody production in response to influenza A virus infection.
Virology journal
Akauliya M,Gautam A,Maharjan S,Park BK,Kim J,Kwon HJ
Published figure using CD23 monoclonal antibody (Product # 25-0232-82) in Flow Cytometry
Thu Dec 10 00:00:00 EST 2020
miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling.
Cell reports
Hines MJ,Coffre M,Mudianto T,Panduro M,Wigton EJ,Tegla C,Osorio-Vasquez V,Kageyama R,Benhamou D,Perez O,Bajwa S,McManus MT,Ansel KM,Melamed D,Koralov SB
25-0232 was used in Flow cytometry/Cell sorting to suggest a critical role for the miR-29-PTEN-PI3K regulatory axis in mature B lymphocytes.
Tue Dec 01 00:00:00 EST 2020
Retroviral Overexpression of CXCR4 on Murine B-1a Cells and Adoptive Transfer for Targeted B-1a Cell Migration to the Bone Marrow and IgM Production.
Journal of visualized experiments : JoVE
Upadhye A,Marshall M,Garmey JC,Bender TP,McNamara C
25-0232 was used in Flow cytometry/Cell sorting to describe a method to target B-1a cell migration to the bone marrow by retroviral-mediated overexpression of the C-X-C motif chemokine receptor 4 (CXCR4).
Sun May 31 00:00:00 EDT 2020
Estrogen Receptor Alpha Signaling Is Responsible for the Female Sex Bias in the Loss of Tolerance and Immune Cell Activation Induced by the Lupus Susceptibility Locus Sle1b.
Frontiers in immunology
Graham JH,Yoachim SD,Gould KA
25-0232 was used in Flow cytometry/Cell sorting to investigate the modulatory role of ERa signalling in Sle1 effects' female sex bias in mice.
Tue Jun 22 00:00:00 EDT 2021
Estrogen Receptor Alpha Signaling Is Responsible for the Female Sex Bias in the Loss of Tolerance and Immune Cell Activation Induced by the Lupus Susceptibility Locus Sle1b.
Frontiers in immunology
Graham JH,Yoachim SD,Gould KA
25-0232 was used in Flow cytometry/Cell sorting to investigate the modulatory role of ERa signalling in Sle1 effects' female sex bias in mice.
Tue Jun 22 00:00:00 EDT 2021
Peritoneal Cells Mediate Immune Responses and Cross-Protection Against Influenza A Virus.
Frontiers in immunology
Gautam A,Park BK,Kim TH,Akauliya M,Kim D,Maharjan S,Park J,Kim J,Lee H,Park MS,Lee Y,Kwon HJ
Published figure using CD23 monoclonal antibody (Product # 25-0232-82) in Flow Cytometry
Mon Aug 17 00:00:00 EDT 2020
Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome.
Nature communications
Komban RJ,Strömberg A,Biram A,Cervin J,Lebrero-Fernández C,Mabbott N,Yrlid U,Shulman Z,Bemark M,Lycke N
Published figure using CD23 monoclonal antibody (Product # 25-0232-82) in Flow Cytometry
Mon Jun 03 00:00:00 EDT 2019
MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner.
Frontiers in immunology
Demeyer A,Skordos I,Driege Y,Kreike M,Hochepied T,Baens M,Staal J,Beyaert R
25-0232 was used in Flow cytometry/Cell sorting to establish that suppression of autoimmune responses is due to the T-cell intrinsic role of MALT1 proteolytic activity.
Mon Oct 05 00:00:00 EDT 2020
c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.
Cell reports
Shikatani EA,Besla R,Ensan S,Upadhye A,Khyzha N,Li A,Emoto T,Chiu F,Degousee N,Moreau JM,Perry HM,Thayaparan D,Cheng HS,Pacheco S,Smyth D,Noyan H,Zavitz CCJ,Bauer CMT,Hilgendorf I,Libby P,Swirski FK,Gommerman JL,Fish JE,Stampfli MR,Cybulsky MI,Rubin BB,Paige CJ,Bender TP,McNamara CA,Husain M,Robbins CS
25-0232-82 was used in Flow Cytometry to identify the nuclear transcription factor c-Myb as an important mediator of atherosclerotic disease in mice.
Tue May 21 00:00:00 EDT 2019
TLR9 Signaling Suppresses the Canonical Plasma Cell Differentiation Program in Follicular B Cells.
Frontiers in immunology
Baptista BJA,Granato A,Canto FB,Montalvão F,Tostes L,de Matos Guedes HL,Coutinho A,Bellio M,Vale AM,Nobrega A
25-0232 was used in Flow cytometry/Cell sorting to identify unexpected, opposing roles for Toll-like receptor4 and TLR9 in the control of plasma B cell differentiation programmes.
Mon Sep 30 00:00:00 EDT 2019
Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells.
Frontiers in immunology
Bai WJ,Li CG,Zhang CC,Xu LH,Zeng QZ,Hu B,Hong Z,He XH,Ouyang DY
Published figure using CD23 monoclonal antibody (Product # 25-0232-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
B cell subsets are modulated during allergic airway inflammation but are not required for the development of respiratory tolerance in a murine model.
European journal of immunology
Habener A,Behrendt AK,Skuljec J,Jirmo AC,Meyer-Bahlburg A,Hansen G
25-0232 was used in Flow cytometry/Cell sorting to investigate how B cells are affected by induction of allergic airway inflammation and respiratory tolerance.
Wed Mar 01 00:00:00 EST 2017
Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.
Journal of immunology (Baltimore, Md. : 1950)
Tang H,Wang H,Lin Q,Fan F,Zhang F,Peng X,Fang X,Liu J,Ouyang K
25-0232 was used in Flow cytometry/Cell sorting to determine the function of 1,4,5-trisphosphate receptor-mediated Ca2+ release in B cells.
Sat Jul 15 00:00:00 EDT 2017
Age-Associated B Cells Express a Diverse Repertoire of VH and Vκ Genes with Somatic Hypermutation.
Journal of immunology (Baltimore, Md. : 1950)
Russell Knode LM,Naradikian MS,Myles A,Scholz JL,Hao Y,Liu D,Ford ML,Tobias JW,Cancro MP,Gearhart PJ
25-0232 was used in Flow cytometry/Cell sorting to show that quiescent ABCs are Ag-experienced cells that accumulate during T cell-dependent responses to diverse Ags during the life of an individual.
Wed Mar 01 00:00:00 EST 2017
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
25-0232 was used in Flow cytometry/Cell sorting to study how OTULIN may be critical in restraining life-threatening spontaneous inflammation and maintaining immune homeostasis.
Thu Aug 25 00:00:00 EDT 2016
Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms.
Blood
Lykken JM,Horikawa M,Minard-Colin V,Kamata M,Miyagaki T,Poe JC,Tedder TF
25-0232 was used in Flow cytometry/Cell sorting to elucidate the mechanisms through which non-Hodgkin lymphomas initially resist or gain resistance to immunotherapy.
Thu Apr 14 00:00:00 EDT 2016
Prolactin Rescues Immature B-Cells from Apoptosis Induced by B-Cell Receptor Cross-Linking.
Journal of immunology research
Flores-Fernández R,Blanco-Favela F,Fuentes-Pananá EM,Chávez-Sánchez L,Gorocica-Rosete P,Pizaña-Venegas A,Chávez-Rueda AK
25-0232 was used in Flow cytometry/Cell sorting to determine the effect of prolactin in an in vitro system of B-cell tolerance, showing that it rescues immature B-cells from apoptosis induced by B-cell receptor cross-linking.
Mon Mar 06 00:00:00 EST 2017
IgD attenuates the IgM-induced anergy response in transitional and mature B cells.
Nature communications
Sabouri Z,Perotti S,Spierings E,Humburg P,Yabas M,Bergmann H,Horikawa K,Roots C,Lambe S,Young C,Andrews TD,Field M,Enders A,Reed JH,Goodnow CC
25-0232 was used in Flow cytometry/Cell sorting to define the RNA landscape of the in vivo anergy response, comprising 220 induced sequences including a core set of 97.
Thu Nov 10 00:00:00 EST 2016
ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes.
PloS one
Yabas M,Jing W,Shafik S,Bröer S,Enders A
25-0232 was used in Flow cytometry/Cell sorting to identify the P4-type ATPase ATP11C as a flippase that selectively transports phosphatidylserine and phosphatidylethanolamine to the inner leaflet of the plasma membrane in immune cells.
Mon Jul 25 00:00:00 EDT 2016
Mantle cell lymphoma in cyclin D1 transgenic mice with Bim-deficient B cells.
Blood
Katz SG,Labelle JL,Meng H,Valeriano RP,Fisher JK,Sun H,Rodig SJ,Kleinstein SH,Walensky LD
Published figure using CD23 monoclonal antibody (Product # 25-0232-82) in Flow Cytometry
Thu Feb 06 00:00:00 EST 2014
IL-4 regulates Bim expression and promotes B cell maturation in synergy with BAFF conferring resistance to cell death at negative selection checkpoints.
Journal of immunology (Baltimore, Md. : 1950)
Granato A,Hayashi EA,Baptista BJ,Bellio M,Nobrega A
25-0232 was used in Flow cytometry/Cell sorting to analyze the effect of IL-4 on B cell maturation, and its influence on BCR-mediated negative selection.
Sun Jun 15 00:00:00 EDT 2014
Enhanced auto-antibody production and Mott cell formation in FcμR-deficient autoimmune mice.
International immunology
Honjo K,Kubagawa Y,Suzuki Y,Takagi M,Ohno H,Bucy RP,Izui S,Kubagawa H
25-0232 was used in Flow cytometry/Cell sorting to determine the impact of Fcmr ablation on autoimmunity.
Mon Dec 01 00:00:00 EST 2014
Intrinsic molecular factors cause aberrant expansion of the splenic marginal zone B cell population in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950)
Stolp J,Mariño E,Batten M,Sierro F,Cox SL,Grey ST,Silveira PA
25-0232 was used in Flow cytometry/Cell sorting to investigate the underlying causes of augmented marginal zone B cell production in NOD mice.
Mon Jul 01 00:00:00 EDT 2013
Galectin 1 modulates plasma cell homeostasis and regulates the humoral immune response.
Journal of immunology (Baltimore, Md. : 1950)
Anginot A,Espeli M,Chasson L,Mancini SJ,Schiff C
25-0232 was used in Flow cytometry/Cell sorting to elucidate the pattern of GAL1 expression and the function of GAL1 in B cells.
Sat Jun 01 00:00:00 EDT 2013
Prolactin levels correlate with abnormal B cell maturation in MRL and MRL/lpr mouse models of systemic lupus erythematosus-like disease.
Clinical & developmental immunology
Legorreta-Haquet MV,Flores-Fernández R,Blanco-Favela F,Fuentes-Pananá EM,Chávez-Sánchez L,Hernández-González R,Tesoro-Cruz E,Arriaga-Pizano L,Chávez-Rueda AK
25-0232 was used in Flow cytometry/Cell sorting to determine the level of PRL receptor expression during bone-marrow B-cell development and assess relevance in disease outcomes in lupus-prone murine models.
Mon Aug 04 00:00:00 EDT 2014
IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.
Blood
Balkhi MY,Willette-Brown J,Zhu F,Chen Z,Liu S,Guttridge DC,Karin M,Hu Y
25-0232-82 was used in Flow Cytometry to demonstrate that IKKα regulates B-lineage commitment via combined canonical and noncanonical NF-κB transcriptional activities to target Pax5 expression during hematopoiesis.
Thu Jun 07 00:00:00 EDT 2012
Splenic morphological changes are accompanied by altered baseline immunity in a mouse model of sickle-cell disease.
The American journal of pathology
Szczepanek SM,McNamara JT,Secor ER,Natarajan P,Guernsey LA,Miller LA,Ballesteros E,Jellison E,Thrall RS,Andemariam B
25-0232 was used in Flow cytometry/Cell sorting to investigate the relationship between functional asplenia from infarctions and increased infectious mortality in a mouse model of sickle-cell disease.
Thu Nov 01 00:00:00 EDT 2012
Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.
Journal of immunology (Baltimore, Md. : 1950)
Yu M,Chen Y,He Y,Podd A,Fu G,Wright JA,Kleiman E,Khan WN,Wen R,Wang D
Published figure using CD23 monoclonal antibody (Product # 25-0232-82) in Flow Cytometry
Sat Dec 01 00:00:00 EST 2012
The role of sphingosine-1-phosphate transporter Spns2 in immune system function.
Journal of immunology (Baltimore, Md. : 1950)
Nijnik A,Clare S,Hale C,Chen J,Raisen C,Mottram L,Lucas M,Estabel J,Ryder E,Adissu H,Adams NC,Ramirez-Solis R,White JK,Steel KP,Dougan G,Hancock RE
25-0232 was used in Flow cytometry/Cell sorting to study the roles of Spns2 in mammals and its involvement in the different S1P-dependent physiological processes.
Sun Jul 01 00:00:00 EDT 2012
Marginal zone B cells regulate antigen-specific T cell responses during infection.
Journal of immunology (Baltimore, Md. : 1950)
Bankoti R,Gupta K,Levchenko A,Stäger S
25-0232 was used in Flow cytometry/Cell sorting to investigate the role of B cells in the regulation of antigen-specific CD8+ T cell responses in a murine model of visceral leishmaniasis.
Sun Apr 15 00:00:00 EDT 2012
Direct reduction of antigen receptor expression in polyclonal B cell populations developing in vivo results in light chain receptor editing.
Journal of immunology (Baltimore, Md. : 1950)
Shen S,Manser T
25-0232 was used in Flow cytometry/Cell sorting to test the role of BCR expression plays in receptor editing in an polyclonal, in vivo population of B cells.
Sun Jan 01 00:00:00 EST 2012
The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.
Molecular immunology
Aragon IV,Barrington RA,Jackowski S,Mori K,Brewer JW
25-0232 was used in Flow cytometry/Cell sorting to demonstrate that a specialised B cell UPR relies exclusively on the IRE1-XBP1 pathway to remodel the ER and expand secretory capacity.
Sun Jul 01 00:00:00 EDT 2012
Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment.
BMC immunology
Ledesma-Soto Y,Blanco-Favela F,Fuentes-Pananá EM,Tesoro-Cruz E,Hernández-González R,Arriaga-Pizano L,Legorreta-Haquet MV,Montoya-Diaz E,Chávez-Sánchez L,Castro-Mussot ME,Chávez-Rueda AK
25-0232 was used in Flow cytometry/Cell sorting to determine if different splenic B cell subsets express the prolactin receptor and if the presence of prolactin influences these B cell subsets and correlates with development of lupus.
Fri Mar 09 00:00:00 EST 2012
Cellular competition independent of BAFF/B lymphocyte stimulator results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartments.
Journal of immunology (Baltimore, Md. : 1950)
Nikbakht N,Migone TS,Ward CP,Manser T
25-0232 was used in Flow cytometry/Cell sorting to investigate the role of the peripheral B cell pro-survival cytokine BAFF/BLyS in the regulation of immunological tolerance and autoreactive cells.
Fri Jul 01 00:00:00 EDT 2011
Impaired B cell development in the absence of Krüppel-like factor 3.
Journal of immunology (Baltimore, Md. : 1950)
Vu TT,Gatto D,Turner V,Funnell AP,Mak KS,Norton LJ,Kaplan W,Cowley MJ,Agenès F,Kirberg J,Brink R,Pearson RC,Crossley M
25-0232 was used in Flow cytometry/Cell sorting to examine the function of Klf3 in B cell development by studying B lymphopoiesis in a Klf3 knockout mouse model.
Tue Nov 15 00:00:00 EST 2011
HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species.
Nature immunology
Capasso M,Bhamrah MK,Henley T,Boyd RS,Langlais C,Cain K,Dinsdale D,Pulford K,Khan M,Musset B,Cherny VV,Morgan D,Gascoyne RD,Vigorito E,DeCoursey TE,MacLennan IC,Dyer MJ
25-0232 was used in Flow cytometry/Cell sorting to investigate how HVCN1 modulates BCR signal strength through regulation of BCR-dependent generation of reactive oxygen species.
Mon Mar 01 00:00:00 EST 2010
Conditional TPM3-ALK and NPM-ALK transgenic mice develop reversible ALK-positive early B-cell lymphoma/leukemia.
Blood
Giuriato S,Foisseau M,Dejean E,Felsher DW,Al Saati T,Demur C,Ragab A,Kruczynski A,Schiff C,Delsol G,Meggetto F
25-0232 was used in Flow cytometry/Cell sorting to develop conditional mouse models for anaplastic lymphoma kinase-induced lymphomagenesis.
Thu May 20 00:00:00 EDT 2010
Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen.
Journal of immunology (Baltimore, Md. : 1950)
Duong BH,Ota T,Aït-Azzouzene D,Aoki-Ota M,Vela JL,Huber C,Walsh K,Gavin AL,Nemazee D
25-0232 was used in Flow cytometry/Cell sorting to generate mice which ubiquitously expressed a membrane-bound IgD-superantigen, to provide a model which should facilitate studies of peripheral B cell tolerance in future.
Thu Apr 15 00:00:00 EDT 2010
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
Blood
Schuman J,Chen Y,Podd A,Yu M,Liu HH,Wen R,Chen ZJ,Wang D
Published figure using CD23 monoclonal antibody (Product # 25-0232-82) in Flow Cytometry
Thu May 07 00:00:00 EDT 2009
