Product References
Fusobacterium nucleatum induces a tumor microenvironment with diminished adaptive immunity against colorectal cancers.
Frontiers in cellular and infection microbiology
Kim HS,Kim CG,Kim WK,Kim KA,Yoo J,Min BS,Paik S,Shin SJ,Lee H,Lee K,Kim H,Shin EC,Kim TM,Ahn JB
11-0458-42 was used in Flow cytometry/Cell sorting to suggest a potential association for FN in adaptive immunity, with biological and prognostic implications.
Mon Mar 27 00:00:00 EDT 2023
HLA-independent T cell receptors for targeting tumors with low antigen density.
Nature medicine
Mansilla-Soto J,Eyquem J,Haubner S,Hamieh M,Feucht J,Paillon N,Zucchetti AE,Li Z,Sjöstrand M,Lindenbergh PL,Saetersmoen M,Dobrin A,Maurin M,Iyer A,Garcia Angus A,Miele MM,Zhao Z,Giavridis T,van der Stegen SJC,Tamzalit F,Rivière I,Huse M,Hendrickson RC,Hivroz C,Sadelain M
11-0458-42 was used in Flow cytometry/Cell sorting to demonstrate that the functional persistence of HIT T cells can be augmented by constitutive coexpression of CD80 and 4-1BBL.
Tue Feb 01 00:00:00 EST 2022
ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis.
Nature communications
Ramirez NP,Lee J,Zheng Y,Li L,Dennis B,Chen D,Challa A,Planelles V,Westover KD,Alto NM,D'Orso I
11-0458-42 was used in Flow Cytometry to define ADAP1 as an unexpected tuner of T cell programs facilitating HIV-1 latency escape.
Tue Mar 01 00:00:00 EST 2022
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.
The Journal of experimental medicine
Louka E,Povinelli B,Rodriguez-Meira A,Buck G,Wen WX,Wang G,Sousos N,Ashley N,Hamblin A,Booth CAG,Roy A,Elliott N,Iskander D,de la Fuente J,Fordham N,O'Byrne S,Inglott S,Norfo R,Salio M,Thongjuea S,Rao A,Roberts I,Mead AJ
Published figure using CD45RA monoclonal antibody (Product # 11-0458-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Dysregulated Peripheral Invariant Natural Killer T Cells in Plaque Psoriasis Patients.
Frontiers in cell and developmental biology
Hu Y,Chen Y,Chen Z,Zhang X,Guo C,Yu Z,Xu P,Sun L,Zhou X,Gong Y,Yu Q,Shi Y
11-0458-42 was used in Flow cytometry/Cell sorting to explore the expression of iNKT cells in psoriasis patients and the effect of secukinumab on them.
Wed Feb 23 00:00:00 EST 2022
Protective heterologous T cell immunity in COVID-19 induced by the trivalent MMR and Tdap vaccine antigens.
Med (New York, N.Y.)
Mysore V,Cullere X,Settles ML,Ji X,Kattan MW,Desjardins M,Durbin-Johnson B,Gilboa T,Baden LR,Walt DR,Lichtman AH,Jehi L,Mayadas TN
11-0458-42 was used in Flow Cytometry to study whether prior Measles-Mumps-Rubella (MMR) or Tetanus-Diptheria-Pertussis (Tdap) vaccination elicit cross-reactive T cells that mitigate COVID-19.
Fri Sep 10 00:00:00 EDT 2021
Immune signature of CCR7+ central memory T cells associates with disease severity and Immunoglobulin E in bronchial asthma.
European annals of allergy and clinical immunology
Moaaz M,Youssry S,Baess A,Abed A,Moaaz M
11-0458 was used in Flow cytometry/Cell sorting to evaluate the possible association of chemokine receptor 7 + memory CD4 + T cells and CCR4 + effector T cells with disease severity and immunoglobulin E production.
Sat May 01 00:00:00 EDT 2021
Differences in Maturation Status and Immune Phenotypes of Circulating Helios+ and Helios- Tregs and Their Disrupted Correlations With Monocyte Subsets in Autoantibody-Positive T1D Individuals.
Frontiers in immunology
Zhang Y,Zhang J,Shi Y,Shen M,Lv H,Chen S,Feng Y,Chen H,Xu X,Yang T,Xu K
Published figure using CD45RA monoclonal antibody (Product # 11-0458-42) in Flow Cytometry
Wed Sep 15 00:00:00 EDT 2021
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
Cell
Pasciuto E,Burton OT,Roca CP,Lagou V,Rajan WD,Theys T,Mancuso R,Tito RY,Kouser L,Callaerts-Vegh Z,de la Fuente AG,Prezzemolo T,Mascali LG,Brajic A,Whyte CE,Yshii L,Martinez-Muriana A,Naughton M,Young A,Moudra A,Lemaitre P,Poovathingal S,Raes J,De Strooper B,Fitzgerald DC,Dooley J,Liston A
11-0458 was used in Flow cytometry/Cell sorting to investigate the function of brain-resident CD4 T cells.
Thu Aug 06 00:00:00 EDT 2020
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease.
Cell
Lee JY,Hall JA,Kroehling L,Wu L,Najar T,Nguyen HH,Lin WY,Yeung ST,Silva HM,Li D,Hine A,Loke P,Hudesman D,Martin JC,Kenigsberg E,Merad M,Khanna KM,Littman DR
11-0458 was used in Flow cytometry/Cell sorting to suggest that serum amyloid A proteins direct a pathogenic pro-inflammatory Th17 cell differentiation program and promote Th17-mediated inflammatory diseases.
Thu Jan 09 00:00:00 EST 2020
Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets.
Molecular cell
Psaila B,Wang G,Rodriguez-Meira A,Li R,Heuston EF,Murphy L,Yee D,Hitchcock IS,Sousos N,O'Sullivan J,Anderson S,Senis YA,Weinberg OK,Calicchio ML,Iskander D,Royston D,Milojkovic D,Roberts I,Bodine DM,Thongjuea S,Mead AJ
Published figure using CD45RA monoclonal antibody (Product # 11-0458-42) in Flow Cytometry
Thu May 07 00:00:00 EDT 2020
The TCR Repertoire Reconstitution in Multiple Sclerosis: Comparing One-Shot and Continuous Immunosuppressive Therapies.
Frontiers in immunology
Amoriello R,Greiff V,Aldinucci A,Bonechi E,Carnasciali A,Peruzzi B,Repice AM,Mariottini A,Saccardi R,Mazzanti B,Massacesi L,Ballerini C
11-0458-42 was used in Flow Cytometry to suggest that the majority of public TCRs belonged to virus-associated sequences.
Fri Mar 26 00:00:00 EDT 2021
The downregulated membrane expression of CD18 in CD34+ cells defines a primitive population of human hematopoietic stem cells.
Stem cell research & therapy
Mesa-Núñez C,Leon-Rico D,Aldea M,Damián C,Sanchez-Baltasar R,Sanchez R,Alberquilla O,Segovia JC,Bueren JA,Almarza E
Published figure using CD45RA monoclonal antibody (Product # 11-0458-42) in Flow Cytometry
Tue Apr 28 00:00:00 EDT 2020
MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo.
Molecular medicine reports
Lv M,Li Z,Liu J,Lin F,Zhang Q,Li Z,Wang Y,Wang K,Xu Y
Published figure using CD45RA monoclonal antibody (Product # 11-0458-42) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.
Nature communications
Bell CC,Fennell KA,Chan YC,Rambow F,Yeung MM,Vassiliadis D,Lara L,Yeh P,Martelotto LG,Rogiers A,Kremer BE,Barbash O,Mohammad HP,Johanson TM,Burr ML,Dhar A,Karpinich N,Tian L,Tyler DS,MacPherson L,Shi J,Pinnawala N,Yew Fong C,Papenfuss AT,Grimmond SM,Dawson SJ,Allan RS,Kruger RG,Vakoc CR,Goode DL,Naik SH,Gilan O,Lam EYN,Marine JC,Prinjha RK,Dawson MA
Published figure using CD45RA monoclonal antibody (Product # 11-0458-42) in Flow Cytometry
Thu Jun 20 00:00:00 EDT 2019
Frequency determination of breast tumor-reactive CD4 and CD8 T cells in humans: unveiling the antitumor immune response.
Oncoimmunology
Pinho MP,Patente TA,Flatow EA,Sallusto F,Barbuto JAM
11-0458-42 was used in Flow cytometry/Cell sorting to describe a strategy that allows this determination, in both CD4 and CD8 compartments, using T cell proliferation induced by tumor cell-lysate pulsed dendritic cells as the readout.
Tue Jan 12 00:00:00 EST 2021
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency.
Nature immunology
Kong XF,Martinez-Barricarte R,Kennedy J,Mele F,Lazarov T,Deenick EK,Ma CS,Breton G,Lucero KB,Langlais D,Bousfiha A,Aytekin C,Markle J,Trouillet C,Jabot-Hanin F,Arlehamn CSL,Rao G,Picard C,Lasseau T,Latorre D,Hambleton S,Deswarte C,Itan Y,Abarca K,Moraes-Vasconcelos D,Ailal F,Ikinciogullari A,Dogu F,Benhsaien I,Sette A,Abel L,Boisson-Dupuis S,Schröder B,Nussenzweig MC,Liu K,Geissmann F,Tangye SG,Gros P,Sallusto F,Bustamante J,Casanova JL
11-0458-42 was used in Flow Cytometry to suggest that inherited SPPL2a deficiency in humans underlies mycobacterial disease by decreasing the numbers of cDC2s and impairing IFN-γ production by mycobacterium-specific memory TH1* cells.
Sat Sep 01 00:00:00 EDT 2018
Effects of Glycogen Synthase Kinase-3β Inhibitor TWS119 on Proliferation and Cytokine Production of TILs From Human Lung Cancer.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Tang YY,Sheng SY,Lu CG,Zhang YQ,Zou JY,Lei YY,Gu Y,Hong H
11-0458 was used in Flow cytometry/Cell sorting to study glycogen synthase kinase-3β inhibitor TWS119 effects on CD4 and CD8 T cells in tumor-infiltrating lymphocytes.
Sat Sep 01 00:00:00 EDT 2018
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection.
Nature
Eyquem J,Mansilla-Soto J,Giavridis T,van der Stegen SJ,Hamieh M,Cunanan KM,Odak A,Gönen M,Sadelain M
Published figure using CD45RA monoclonal antibody (Product # 11-0458-42) in Flow Cytometry
Thu Mar 02 00:00:00 EST 2017
Distinct signaling programs control human hematopoietic stem cell survival and proliferation.
Blood
Knapp DJ,Hammond CA,Aghaeepour N,Miller PH,Pellacani D,Beer PA,Sachs K,Qiao W,Wang W,Humphries RK,Sauvageau G,Zandstra PW,Bendall SC,Nolan GP,Hansen C,Eaves CJ
11-0458 was used in Flow cytometry/Cell sorting to investigate the molecular mechanisms by which distinct signalling programs control human hematopoietic stem cell survival and proliferation.
Thu Jan 19 00:00:00 EST 2017
Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency.
The Journal of clinical investigation
Cottineau J,Kottemann MC,Lach FP,Kang YH,Vély F,Deenick EK,Lazarov T,Gineau L,Wang Y,Farina A,Chansel M,Lorenzo L,Piperoglou C,Ma CS,Nitschke P,Belkadi A,Itan Y,Boisson B,Jabot-Hanin F,Picard C,Bustamante J,Eidenschenk C,Boucherit S,Aladjidi N,Lacombe D,Barat P,Qasim W,Hurst JA,Pollard AJ,Uhlig HH,Fieschi C,Michon J,Bermudez VP,Abel L,de Villartay JP,Geissmann F,Tangye SG,Hurwitz J,Vivier E,Casanova JL,Smogorzewska A,Jouanguy E
11-0458 was used in Flow cytometry/Cell sorting to study 5 patients from 4 kindreds, all of whom displayed intrauterine growth retardation, chronic neutropenia, and NK cell deficiency.
Mon May 01 00:00:00 EDT 2017
The distribution and function of human memory T cell subsets in lung cancer.
Immunologic research
Sheng SY,Gu Y,Lu CG,Zou JY,Hong H,Wang R
Published figure using CD45RA monoclonal antibody (Product # 11-0458-42) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia.
Oncoimmunology
Catakovic K,Gassner FJ,Ratswohl C,Zaborsky N,Rebhandl S,Schubert M,Steiner M,Gutjahr JC,Pleyer L,Egle A,Hartmann TN,Greil R,Geisberger R
Published figure using CD45RA monoclonal antibody (Product # 11-0458-42) in Flow Cytometry
Sat Jan 29 00:00:00 EST 2022
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4.
Nature communications
Campos Carrascosa L,Klein M,Kitagawa Y,Lückel C,Marini F,König A,Guralnik A,Raifer H,Hagner-Benes S,Rädler D,Böck A,Kang C,Lohoff M,Garn H,Schaub B,Berberich-Siebelt F,Sakaguchi S,Bopp T,Huber M
11-0458 was used in Flow cytometry/Cell sorting to study the opposing effects of interferon regulatory factor1 and IRF4 on T helper 9 cell differentiation.
Fri May 12 00:00:00 EDT 2017
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
11-0458 was used in Flow cytometry/Cell sorting to identify functionally distinct adaptive GPCR heterogeneity patternation in mice.
Thu Aug 03 00:00:00 EDT 2017
Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor.
The Journal of clinical investigation
MacDonald KG,Hoeppli RE,Huang Q,Gillies J,Luciani DS,Orban PC,Broady R,Levings MK
11-0458 was used in Flow cytometry/Cell sorting to investigate alloantigen-specific regulatory T cells generated with a chimeric antigen receptor.
Fri Apr 01 00:00:00 EDT 2016
Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection.
PLoS pathogens
Hoffmann M,Pantazis N,Martin GE,Hickling S,Hurst J,Meyerowitz J,Willberg CB,Robinson N,Brown H,Fisher M,Kinloch S,Babiker A,Weber J,Nwokolo N,Fox J,Fidler S,Phillips R,Frater J
11-0458 was used in Flow cytometry/Cell sorting to identify CD8 T cell exhaustion markers which correlate with HIV-1 disease progression.
Fri Jul 01 00:00:00 EDT 2016
Activation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand.
PLoS pathogens
Tomić A,Varanasi PR,Golemac M,Malić S,Riese P,Borst EM,Mischak-Weissinger E,Guzmán CA,Krmpotić A,Jonjić S,Messerle M
11-0458 was used in Flow cytometry/Cell sorting to investigate a strategy for an HCMV vaccine that aims at the simultaneous activation of innate and adaptive immune responses.
Thu Dec 01 00:00:00 EST 2016
Promoter H3K4 methylation dynamically reinforces activation-induced pathways in human CD4 T cells.
Genes and immunity
LaMere SA,Thompson RC,Komori HK,Mark A,Salomon DR
11-0458 was used in Flow cytometry/Cell sorting to examine genome-wide histone modification dynamics during the activation of human naive and memory CD4 T cells.
Fri Jul 01 00:00:00 EDT 2016
PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer.
Cancer immunology research
Severson JJ,Serracino HS,Mateescu V,Raeburn CD,McIntyre RC,Sams SB,Haugen BR,French JD
11-0458 was used in Flow cytometry/Cell sorting to determine that the release of PD-1 and Tim-3, and the inhibition of Tregs, may encourage tumour elimination in metastatic differentiated thyroid cancer.
Mon Jun 01 00:00:00 EDT 2015
Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.
PloS one
Klarenbeek PL,Doorenspleet ME,Esveldt RE,van Schaik BD,Lardy N,van Kampen AH,Tak PP,Plenge RM,Baas F,de Bakker PI,de Vries N
11-0458 was used in Flow cytometry/Cell sorting to investigate how a single T cell commits to become either CD4+ or CD8+.
Wed Jun 08 00:00:00 EDT 2016
Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features.
Journal of immunology (Baltimore, Md. : 1950)
Arlehamn CL,Seumois G,Gerasimova A,Huang C,Fu Z,Yue X,Sette A,Vijayanand P,Peters B
11045842 was used in flow cytometry to investigate the impact of CCR6(+)CXCR3(+)CCR4(-) cells in latent tuberculosis infection
Mon Sep 15 00:00:00 EDT 2014
CD55 costimulation induces differentiation of a discrete T regulatory type 1 cell population with a stable phenotype.
Journal of immunology (Baltimore, Md. : 1950)
Sutavani RV,Bradley RG,Ramage JM,Jackson AM,Durrant LG,Spendlove I
11-0458 was used in Flow cytometry/Cell sorting to demonstrate that CD55 is a potent costimulator and activator of human naive CD4(+) cells.
Sun Dec 15 00:00:00 EST 2013
Fc receptor-like 3 protein expressed on IL-2 nonresponsive subset of human regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Nagata S,Ise T,Pastan I
11-0458 was used in Flow cytometry/Cell sorting to study the effects of Foxp3 and IL-2 on FCRL3-/+ nTreg cell subsets.
Mon Jun 15 00:00:00 EDT 2009