Product References
Myristica fragrans Extract Inhibits Platelet Desialylation and Activation to Ameliorate Sepsis-Associated Thrombocytopenia in a Murine CLP-Induced Sepsis Model.
International journal of molecular sciences
Jeong SH,Park JY,Ryu YB,Kim WS,Lee IC,Kim JH,Kim D,Ha JH,Lee BW,Nam J,Cho KO,Kwon HJ
Published figure using CD62P (P-Selectin) monoclonal antibody (Product # 12-0626-82) in Flow Cytometry
Tue May 16 00:00:00 EDT 2023
Small-Molecule Cyclophilin Inhibitors Potently Reduce Platelet Procoagulant Activity.
International journal of molecular sciences
Van Bael J,Vandenbulcke A,Ahmed-Belkacem A,Guichou JF,Pawlotsky JM,Samyn J,Barendrecht AD,Maas C,De Meyer SF,Vanhoorelbeke K,Tersteeg C
Published figure using CD62P (P-Selectin) monoclonal antibody (Product # 12-0626-82) in Flow Cytometry
Wed Apr 12 00:00:00 EDT 2023
Whole Blood Procoagulant Platelet Flow Cytometry Protocol for Heparin-Induced Thrombocytopenia (HIT) and Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) Testing.
Methods in molecular biology (Clifton, N.J.)
Lee CSM,Powell MC,Chen VM
12-0626-82 was used in Flow cytometry/Cell sorting to present a protocol for a novel whole blood flow cytometry-based assay to detect procoagulant platelets in healthy donor blood in response to plasma from patients suspected of HIT or VITT.
Mon May 22 00:00:00 EDT 2023
Cyclical depressurization degranulates platelets in an agonist-free mechanism of platelet activation.
PloS one
Velasquez-Mao AJ,Velasquez M,Vandsburger MH
12-0626-82 was used in Flow cytometry/Cell sorting to investigate the mechanobiology of platelet degranulation under hydrostatic depressurization, revealing a unique case where CD62P and PAC1 do not interchangeably indicate platelet activation.
Mon Sep 19 00:00:00 EDT 2022
Involvement of P2Y12 receptors in a nitroglycerin-induced model of migraine in male mice.
British journal of pharmacology
Gölöncsér F,Baranyi M,Iring A,Hricisák L,Otrokocsi L,Benyó Z,Sperlágh B
Published figure using CD62P (P-Selectin) monoclonal antibody (Product # 12-0626-82) in Flow Cytometry
Wed Dec 01 00:00:00 EST 2021
The role of Sphingomyelin synthase 2 (SMS2) in platelet activation and its clinical significance.
Thrombosis journal
Guo Y,Chang L,Zhang G,Gao Z,Lin H,Zhang Y,Hu L,Chen S,Fan B,Zhang S,Xue R
12-0626-82 was used in Flow Cytometry to indicate that SMS2 acts as a positive regulator of platelet activation and thrombosis, and provides a theoretical basis for the potential use of D609 in anti-thrombosis treatment.
Wed Apr 28 00:00:00 EDT 2021
Activation of Platelet NLRP3 Inflammasome in Crohn's Disease.
Frontiers in pharmacology
Zhang G,Chen H,Guo Y,Zhang W,Jiang Q,Zhang S,Han L,Chen S,Xue R
12-0626-82 was used in Flow cytometry/Cell sorting to indicate that the ROS-NLRP3 inflammasome-interleukin-1β axis may contribute to platelet hyperactivity in active CD.
Fri Jul 16 00:00:00 EDT 2021
Mesenchymal stem cells attenuate liver fibrosis by targeting Ly6Chi/lo macrophages through activating the cytokine-paracrine and apoptotic pathways.
Cell death discovery
Li YH,Shen S,Shao T,Jin MT,Fan DD,Lin AF,Xiang LX,Shao JZ
12-0626-82 was used in Flow Cytometry to provide insights into the functional role of bone marrow-derived sesenchymal stem cell in alleviating liver fibrosis.
Mon Sep 13 00:00:00 EDT 2021
Longitudinal RNA-Seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies a Platelet SELP Splice QTL.
Circulation research
Rondina MT,Voora D,Simon LM,Schwertz H,Harper JF,Lee O,Bhatlekar SC,Li Q,Eustes AS,Montenont E,Campbell RA,Tolley ND,Kosaka Y,Weyrich AS,Bray PF,Rowley JW
Published figure using CD62P (P-Selectin) monoclonal antibody (Product # 12-0626-82) in Flow Cytometry
Fri Feb 14 00:00:00 EST 2020
Loss of Tet2 affects platelet function but not coagulation in mice.
Blood science (Baltimore, Md.)
Wang B,Xia M,Chen T,Li M,Shi D,Wang X,Pang A,Zhou J,Yuan W,Chu Y
Published figure using CD62P (P-Selectin) monoclonal antibody (Product # 12-0626-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Expression and Clinical Prognostic Value of Platelet NLRP3 in Acute Coronary Syndrome.
International journal of general medicine
Peng H,Wu H,Zhang G,Zhang W,Guo Y,Chang L,Chen S,Xue R,Zhang S
12-0626 was used in Flow cytometry/Cell sorting to indicate that platelet NLRP3 was a novel potential prognostic factor for patients with acute coronary syndrome that underwent percutaneous coronary intervention.
Sun Apr 17 00:00:00 EDT 2022
Expression and Clinical Prognostic Value of Platelet NLRP3 in Acute Coronary Syndrome.
International journal of general medicine
Peng H,Wu H,Zhang G,Zhang W,Guo Y,Chang L,Chen S,Xue R,Zhang S
12-0626 was used in Flow cytometry/Cell sorting to indicate that platelet NLRP3 was a novel potential prognostic factor for patients with acute coronary syndrome that underwent percutaneous coronary intervention.
Sun Apr 17 00:00:00 EDT 2022
Targeted anti-IL-1β platelet microparticles for cardiac detoxing and repair.
Science advances
Li Z,Hu S,Huang K,Su T,Cores J,Cheng K
12-0626-82 was used in Flow cytometry/Cell sorting to address the issue of conventional IL-1β blockers lacking targeting specificity resulting in increased risk of serious side effects.
Sat Feb 01 00:00:00 EST 2020
Mesenchymal stromal cells lower platelet activation and assist in platelet formation in vitro.
JCI insight
Mendelson A,Strat AN,Bao W,Rosston P,Fallon G,Ohrn S,Zhong H,Lobo C,An X,Yazdanbakhsh K
Published figure using CD62P (P-Selectin) monoclonal antibody (Product # 12-0626-82) in Flow Cytometry
Thu Aug 22 00:00:00 EDT 2019
Circulating apoptotic bodies maintain mesenchymal stem cell homeostasis and ameliorate osteopenia via transferring multiple cellular factors.
Cell research
Liu D,Kou X,Chen C,Liu S,Liu Y,Yu W,Yu T,Yang R,Wang R,Zhou Y,Shi S
12-0626 was used in Flow cytometry/Cell sorting to identify a previously unknown role of apoptotic bodies in maintaining MSC and bone homeostasis in both physiological and pathological contexts and implies the potential use of apoptotic bodies to treat osteoporosis.
Sat Sep 01 00:00:00 EDT 2018
Circulating apoptotic bodies maintain mesenchymal stem cell homeostasis and ameliorate osteopenia via transferring multiple cellular factors.
Cell research
Liu D,Kou X,Chen C,Liu S,Liu Y,Yu W,Yu T,Yang R,Wang R,Zhou Y,Shi S
12-0626 was used in Flow cytometry/Cell sorting to identify a previously unknown role of apoptotic bodies in maintaining MSC and bone homeostasis in both physiological and pathological contexts and implies the potential use of apoptotic bodies to treat osteoporosis.
Sat Sep 01 00:00:00 EDT 2018
Novel antibodies against GPIbα inhibit pulmonary metastasis by affecting vWF-GPIbα interaction.
Journal of hematology & oncology
Qi Y,Chen W,Liang X,Xu K,Gu X,Wu F,Fan X,Ren S,Liu J,Zhang J,Li R,Liu J,Liang X
Published figure using CD62P (P-Selectin) monoclonal antibody (Product # 12-0626-82) in Flow Cytometry
Mon Sep 17 00:00:00 EDT 2018
Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes.
The Journal of clinical investigation
Kraakman MJ,Lee MK,Al-Sharea A,Dragoljevic D,Barrett TJ,Montenont E,Basu D,Heywood S,Kammoun HL,Flynn M,Whillas A,Hanssen NM,Febbraio MA,Westein E,Fisher EA,Chin-Dusting J,Cooper ME,Berger JS,Goldberg IJ,Nagareddy PR,Murphy AJ
Published figure using CD62P (P-Selectin) monoclonal antibody (Product # 12-0626-82) in Flow Cytometry
Thu Jun 01 00:00:00 EDT 2017
The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis.
Nature communications
Qiu C,Wang Y,Zhao H,Qin L,Shi Y,Zhu X,Song L,Zhou X,Chen J,Zhou H,Zhang H,Tellides G,Min W,Yu L
12-0626 was used in Flow cytometry/Cell sorting to determine that SENP1-mediated SUMOylation drives graft arteriosclerosis by regulating the synergistic effect of GATA2 and NF-κB.
Thu Jun 01 00:00:00 EDT 2017
The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis.
Nature communications
Qiu C,Wang Y,Zhao H,Qin L,Shi Y,Zhu X,Song L,Zhou X,Chen J,Zhou H,Zhang H,Tellides G,Min W,Yu L
12-0626 was used in Flow cytometry/Cell sorting to determine that SENP1-mediated SUMOylation drives graft arteriosclerosis by regulating the synergistic effect of GATA2 and NF-κB.
Thu Jun 01 00:00:00 EDT 2017
Refrigerated platelets stored in whole blood up to 5 days adhere to thrombi formed during hemorrhagic hypotension in rats.
Journal of thrombosis and haemostasis : JTH
Torres Filho IP,Torres LN,Valdez C,Salgado C,Cap AP,Dubick MA
Published figure using CD62P (P-Selectin) monoclonal antibody (Product # 12-0626-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Platelet-derived HMGB1 is a critical mediator of thrombosis.
The Journal of clinical investigation
Vogel S,Bodenstein R,Chen Q,Feil S,Feil R,Rheinlaender J,Schäffer TE,Bohn E,Frick JS,Borst O,Münzer P,Walker B,Markel J,Csanyi G,Pagano PJ,Loughran P,Jessup ME,Watkins SC,Bullock GC,Sperry JL,Zuckerbraun BS,Billiar TR,Lotze MT,Gawaz M,Neal MD
Published figure using CD62P (P-Selectin) monoclonal antibody (Product # 12-0626-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin.
Nature communications
Nussbaum C,Bannenberg S,Keul P,Gräler MH,Gonçalves-de-Albuquerque CF,Korhonen H,von Wnuck Lipinski K,Heusch G,de Castro Faria Neto HC,Rohwedder I,Göthert JR,Prasad VP,Haufe G,Lange-Sperandio B,Offermanns S,Sperandio M,Levkau B
12-0626 was used in Flow cytometry/Cell sorting to identify S1P as a direct and indirect contributor to leukocyte rolling and characterise the receptors mediating its action.
Thu Apr 02 00:00:00 EDT 2015
Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin.
Nature communications
Nussbaum C,Bannenberg S,Keul P,Gräler MH,Gonçalves-de-Albuquerque CF,Korhonen H,von Wnuck Lipinski K,Heusch G,de Castro Faria Neto HC,Rohwedder I,Göthert JR,Prasad VP,Haufe G,Lange-Sperandio B,Offermanns S,Sperandio M,Levkau B
12-0626 was used in Flow cytometry/Cell sorting to identify S1P as a direct and indirect contributor to leukocyte rolling and characterise the receptors mediating its action.
Thu Apr 02 00:00:00 EDT 2015
Maresin 1 mitigates LPS-induced acute lung injury in mice.
British journal of pharmacology
Gong J,Wu ZY,Qi H,Chen L,Li HB,Li B,Yao CY,Wang YX,Wu J,Yuan SY,Yao SL,Shang Y
12-0626 was used in Flow cytometry/Cell sorting to demonstrate that high-dose MaR1 mitigates LPS-induced lung injury in mice by inhibiting neutrophil adhesions and decreasing pro-inflammatory cytokines levels.
Tue Jul 01 00:00:00 EDT 2014
Cathepsin G-dependent modulation of platelet thrombus formation in vivo by blood neutrophils.
PloS one
Faraday N,Schunke K,Saleem S,Fu J,Wang B,Zhang J,Morrell C,Dore S
12-0626 was used in Flow cytometry/Cell sorting to demonstrate the potential of neutrophil cathepsin G as a target for novel anti-thrombotic therapies.
Mon Apr 14 00:00:00 EDT 2014