Product References
TLR4 is one of the receptors for Chikungunya virus envelope protein E2 and regulates virus induced pro-inflammatory responses in host macrophages.
Frontiers in immunology
Mahish C,De S,Chatterjee S,Ghosh S,Keshry SS,Mukherjee T,Khamaru S,Tung KS,Subudhi BB,Chattopadhyay S,Chattopadhyay S
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu May 18 00:00:00 EDT 2023
Carvacrol protects mice against LPS-induced sepsis and attenuates inflammatory response in macrophages by modulating the ERK1/2 pathway.
Scientific reports
Yan C,Kuang W,Jin L,Wang R,Niu L,Xie C,Ding J,Liao Y,Wang L,Wan H,Ma G
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Aug 07 00:00:00 EDT 2023
TREM2 expression promotes liver and peritoneal M2 macrophage polarization in mice infected with Schistosoma japonicum.
Journal of cellular and molecular medicine
Zhu D,Huang M,Shen P,Zhang B,Chen G,Chen J,Duan L,Duan Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance.
Bioactive materials
Li W,Yan J,Tian H,Li B,Wang G,Sang W,Zhang Z,Zhang X,Dai Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
BushenHuoxue decoction suppresses M1 macrophage polarization and prevents LPS induced inflammatory bone loss by activating AMPK pathway.
Heliyon
Chen S,Tao L,Zhu F,Wang Z,Zhuang Q,Li Y,Yang Y,Feng C,Shi H,Shi J,Zhu L,Xiao L,Geng D,Wang Z
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2023
CD8α+ dendritic cells potentiate antitumor and immune activities against murine ovarian cancers.
Scientific reports
Lee SW,Lee H,Lee KW,Kim MJ,Kang SW,Lee YJ,Kim H,Kim YM
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Jan 03 00:00:00 EST 2023
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Immunity, inflammation and disease
Tan H,Cao L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Exosomal Lnc NEAT1 from endothelial cells promote bone regeneration by regulating macrophage polarization via DDX3X/NLRP3 axis.
Journal of nanobiotechnology
Chen Y,Wu Y,Guo L,Yuan S,Sun J,Zhao K,Wang J,An R
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Mar 20 00:00:00 EDT 2023
Macrophage Reprogramming via the Modulation of Unfolded Protein Response with siRNA-Loaded Magnetic Nanoparticles in a TAM-like Experimental Model.
Pharmaceutics
D'Urso A,Oltolina F,Borsotti C,Prat M,Colangelo D,Follenzi A
14-0862-82 was used in Flow cytometry/Cell sorting to provide a novel strategy for the development of new tumor immunotherapies in vivo.
Mon Jun 12 00:00:00 EDT 2023
Role of low-intensity pulsed ultrasound in regulating macrophage polarization to accelerate tendon-bone interface repair.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Xu Z,Li S,Wan L,Hu J,Lu H,Zhang T
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2023
BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization.
NPJ Regenerative medicine
Wang J,Xue Y,Wang Y,Liu C,Hu S,Zhao H,Gu Q,Yang H,Huang L,Zhou X,Shi Q
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Feb 09 00:00:00 EST 2023
Hydrogen Attenuates Inflammation by Inducing Early M2 Macrophage Polarization in Skin Wound Healing.
Pharmaceuticals (Basel, Switzerland)
Zhao P,Cai Z,Zhang X,Liu M,Xie F,Liu Z,Lu S,Ma X
14-0862-82 was used in Immunohistochemistry to reveal that H2 could promote very early M1-to-M2 polarization (on days 2-3 post wounding, 2-3 days earlier than in conventional wound healing), without disturbing the functions of the M1 phenotype.
Thu Jun 15 00:00:00 EDT 2023
Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy.
Materials today. Bio
Huang J,Leng X,Jiang T,Xu L,Zheng J,Fang M,Wang J,Wang Z,Zhang L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Axl promotes intracranial aneurysm rupture by regulating macrophage polarization toward M1 via STAT1/HIF-1α.
Frontiers in immunology
Han Y,Li G,Zhang Z,Zhang X,Zhao B,Yang H
14-0862-82 was used in Immunohistochemistry to evaluate the influence of Axl on IA rupture by administrating R428 to inhibit or rmGas6 to activate the Axl receptor in vivo.
Fri May 26 00:00:00 EDT 2023
Axl promotes intracranial aneurysm rupture by regulating macrophage polarization toward M1 via STAT1/HIF-1α.
Frontiers in immunology
Han Y,Li G,Zhang Z,Zhang X,Zhao B,Yang H
14-0862-82 was used in Immunohistochemistry to evaluate the influence of Axl on IA rupture by administrating R428 to inhibit or rmGas6 to activate the Axl receptor in vivo.
Fri May 26 00:00:00 EDT 2023
Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model.
Acta pharmaceutica Sinica. B
Zhang L,Zhu Y,Wei X,Chen X,Li Y,Zhu Y,Xia J,Huang Y,Huang Y,Wang J,Pang Z
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2022
Enhanced uptake and anti-maturation effect of celastrol-loaded mannosylated liposomes on dendritic cells for psoriasis treatment.
Acta pharmaceutica Sinica. B
Xi L,Lin Z,Qiu F,Chen S,Li P,Chen X,Wang Z,Zheng Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Enhancing arginase 2 expression using target site blockers as a strategy to modulate macrophage phenotype.
Molecular therapy. Nucleic acids
De Santi C,Nally FK,Afzal R,Duffy CP,Fitzsimons S,Annett SL,Robson T,Dowling JK,Cryan SA,McCoy CE
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Sep 13 00:00:00 EDT 2022
Oncolytic Zika virus promotes intratumoral T cell infiltration and improves immunotherapy efficacy in glioblastoma.
Molecular therapy oncolytics
Chen L,Zhou C,Chen Q,Shang J,Liu Z,Guo Y,Li C,Wang H,Ye Q,Li X,Zu S,Li F,Xia Q,Zhou T,Li A,Wang C,Chen Y,Wu A,Qin C,Man J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Mar 17 00:00:00 EDT 2022
G9a promotes inflammation in Streptococcus pneumoniae induced pneumonia mice by stimulating M1 macrophage polarization and H3K9me2 methylation in FOXP1 promoter region.
Annals of translational medicine
Li Y,Li G,Zhang L,Li Y,Zhao Z
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2022
Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model.
Frontiers in immunology
Jiang W,Wang X,Su Y,Cai L,Li J,Liang J,Gu Q,Sun M,Shi L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2022
Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.
eLife
Kovacs MA,Cowan MN,Babcock IW,Sibley LA,Still K,Batista SJ,Labuzan SA,Sethi I,Harris TH
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2022
MicroRNA-382 Promotes M2-Like Macrophage via the SIRP-α/STAT3 Signaling Pathway in Aristolochic Acid-Induced Renal Fibrosis.
Frontiers in immunology
Wang X,Jia P,Ren T,Zou Z,Xu S,Zhang Y,Shi Y,Bao S,Li Y,Fang Y,Ding X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Fri May 20 00:00:00 EDT 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Chromomycin A5 induces bona fide immunogenic cell death in melanoma.
Frontiers in immunology
Florêncio KGD,Edson EA,Fernandes KSDS,Luiz JPM,Pinto FDCL,Pessoa ODL,Cunha FQ,Machado-Neto JA,Wilke DV
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Nov 29 00:00:00 EST 2022
In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses.
Nature communications
Guo Y,Wang SZ,Zhang X,Jia HR,Zhu YX,Zhang X,Gao G,Jiang YW,Li C,Chen X,Wu SY,Liu Y,Wu FG
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Targeting dendritic cells with TLR-2 ligand-coated nanoparticles loaded with Mycobacterium tuberculosis epitope induce antituberculosis immunity.
The Journal of biological chemistry
Kumar Das D,Zafar MA,Nanda S,Singh S,Lamba T,Bashir H,Singh P,Maurya SK,Nadeem S,Sehrawat S,Bhalla V,Agrewala JN
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling.
Molecular cancer
Rizzello C,Cancila V,Sangaletti S,Botti L,Ratti C,Milani M,Dugo M,Bertoni F,Tripodo C,Chiodoni C,Colombo MP
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Dec 12 00:00:00 EST 2022
Dental pulp stem cell-derived exosomes suppress M1 macrophage polarization through the ROS-MAPK-NFκB P65 signaling pathway after spinal cord injury.
Journal of nanobiotechnology
Liu C,Hu F,Jiao G,Guo Y,Zhou P,Zhang Y,Zhang Z,Yi J,You Y,Li Z,Wang H,Zhang X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Feb 02 00:00:00 EST 2022
Self-assembled traditional Chinese nanomedicine modulating tumor immunosuppressive microenvironment for colorectal cancer immunotherapy.
Theranostics
Mao Q,Min J,Zeng R,Liu H,Li H,Zhang C,Zheng A,Lin J,Liu X,Wu M
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Sep 29 00:00:00 EDT 2022
Role of circular RNA cdr1as in modulation of macrophage phenotype.
Life sciences
Gonzalez C,Cimini M,Cheng Z,Benedict C,Wang C,Trungcao M,Mallaredy V,Rajan S,Garikipati VNS,Kishore R
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Nov 15 00:00:00 EST 2022
A ROS-responsive, self-immolative and self-reporting hydrogen sulfide donor with multiple biological activities for the treatment of myocardial infarction.
Bioactive materials
Yao M,Lu Y,Shi L,Huang Y,Zhang Q,Tan J,Hu P,Zhang J,Luo G,Zhang N
14-0862-82 was used in Immunocytochemistry to conclude that this ROS-responsive, self-immolative, and fluorescent H2S donor can serve as a new theranostic agent for MI and other ischemic diseases.
Tue Mar 01 00:00:00 EST 2022
Tumor necrosis factor-α-primed mesenchymal stem cell-derived exosomes promote M2 macrophage polarization via Galectin-1 and modify intrauterine adhesion on a novel murine model.
Frontiers in immunology
Li J,Pan Y,Yang J,Wang J,Jiang Q,Dou H,Hou Y
14-0862-82 was used in Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Neutralization to propose an innovative mouse model and a better MSC treatment strategy for IUA.
Wed Jan 11 00:00:00 EST 2023
A bilirubin-derived nanomedicine attenuates the pathological cascade of pulmonary fibrosis.
Biomaterials
Keum H,Kim D,Kim J,Kim TW,Whang CH,Jung W,Jon S
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
CD11b Deficiency Exacerbates Methicillin-Resistant Staphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages.
Immune network
Sim H,Jeong D,Kim HI,Pak S,Thapa B,Kwon HJ,Lee K
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Pseudomonas aeruginosa PcrV Enhances the Nitric Oxide-Mediated Tumoricidal Activity of Tumor-Associated Macrophages via a TLR4/PI3K/AKT/mTOR-Glycolysis-Nitric Oxide Circuit.
Frontiers in oncology
Yu H,Bai Y,Qiu J,He X,Xiong J,Dai Q,Wang X,Li Y,Sheng H,Xin R,Jiang L,Li Q,Li D,Zhang H,Zhang L,Chen Q,Peng J,Hu X,Zhang K
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Dec 15 00:00:00 EST 2021
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Exosomes derived from inflammatory myoblasts promote M1 polarization and break the balance of myoblast proliferation/differentiation.
World journal of stem cells
Luo ZW,Sun YY,Lin JR,Qi BJ,Chen JW
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Fri Nov 26 00:00:00 EST 2021
Altered Corneal Epithelial Dendritic Cell Morphology and Phenotype Following Acute Exposure to Hyperosmolar Saline.
Investigative ophthalmology & visual science
Senthil K,Jiao H,Downie LE,Chinnery HR
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Immunocytochemistry
Mon Feb 01 00:00:00 EST 2021
Myeloid and plasmacytoid dendritic cell combined vaccines loaded with heat-treated tumor cell lysates enhance antitumor activity in murine lung cancer.
Oncology letters
Chen H,Tan J,Li X,Li H,Wu W,Wu Y,Zhang J,Gu L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus.
Cells
Jhan MK,Chen CL,Shen TJ,Tseng PC,Wang YT,Satria RD,Yu CY,Lin CF
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Nov 15 00:00:00 EST 2021
Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen.
Cell reports
Boccasavia VL,Bovolenta ER,Villanueva A,Borroto A,Oeste CL,van Santen HM,Prieto C,Alonso-López D,Diaz-Muñoz MD,Batista FD,Alarcón B
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Immunocytochemistry
Tue Mar 16 00:00:00 EDT 2021
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Journal for immunotherapy of cancer
Wang Z,Xu F,Hu J,Zhang H,Cui L,Lu W,He W,Wang X,Li M,Zhang H,Xiong W,Xie C,Liu Y,Zhou P,Liu J,Huang P,Qin XF,Xia X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge.
Cell reports
Jiang W,Shi L,Cai L,Wang X,Li J,Li H,Liang J,Gu Q,Ji G,Li J,Liu L,Sun M
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Dec 14 00:00:00 EST 2021
Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis.
Nature communications
Li H,Wang M,Huang B,Zhu SW,Zhou JJ,Chen DR,Cui R,Zhang M,Sun ZJ
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Dec 09 00:00:00 EST 2021
Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.
Journal of neuroinflammation
Oladiran O,Shi XQ,Yang M,Fournier S,Zhang J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Mar 22 00:00:00 EDT 2021
Adrenomedullin 2 improves bone regeneration in type 1 diabetic rats by restoring imbalanced macrophage polarization and impaired osteogenesis.
Stem cell research & therapy
Wang F,Kong L,Wang W,Shi L,Wang M,Chai Y,Xu J,Kang Q
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu May 13 00:00:00 EDT 2021
Marine-inspired molecular mimicry generates a drug-free, but immunogenic hydrogel adhesive protecting surgical anastomosis.
Bioactive materials
Huang J,Jiang Y,Liu Y,Ren Y,Xu Z,Li Z,Zhao Y,Wu X,Ren J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.
Frontiers in immunology
Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Feb 10 00:00:00 EST 2022
C-Reactive Protein Suppresses the Th17 Response Indirectly by Attenuating the Antigen Presentation Ability of Monocyte Derived Dendritic Cells in Experimental Autoimmune Encephalomyelitis.
Frontiers in immunology
Shen ZY,Zheng Y,Pecsok MK,Wang K,Li W,Gong MJ,Wu F,Zhang L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Frontiers in immunology
Lv N,Jin S,Liang Z,Wu X,Kang Y,Su L,Dong Y,Wang B,Ma T,Shi L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Feb 28 00:00:00 EST 2022
Mincle/Syk Signalling Promotes Intestinal Mucosal Inflammation Through Induction of Macrophage Pyroptosis in Crohn's Disease.
Journal of Crohn's & colitis
Gong W,Zheng T,Guo K,Fang M,Xie H,Li W,Tang Q,Hong Z,Ren H,Gu G,Wang G,Wu X,Zhao Y,Ren J
14-0862 was used in Flow cytometry/Cell sorting to show that Mincle signaling is significantly elevated in active human CD and experimental colitis, and macrophages are the principal leukocyte subset that up-regulate Mincle signaling.
Wed Dec 02 00:00:00 EST 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Mesenchymal stem cell-secreted extracellular vesicles carrying TGF-β1 up-regulate miR-132 and promote mouse M2 macrophage polarization.
Journal of cellular and molecular medicine
Wang Y,Han B,Wang Y,Wang C,Zhang H,Xue J,Wang X,Niu T,Niu Z,Chen Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Interleukin-9 Inhibits Lung Metastasis of Melanoma through Stimulating Anti-Tumor M1 Macrophages.
Molecules and cells
Park SM,Do-Thi VA,Lee JO,Lee H,Kim YS
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sun May 31 00:00:00 EDT 2020
Effects of combined treatment with PD‑L1 Ig and CD40L mAb on immune tolerance in the CBA/J x DBA/2 mouse model.
Molecular medicine reports
Li G,Yang L,Li D,Zhang J,Du L,Xia L,Liu Y,Hu W
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Angiotensin II induces RAW264.7 macrophage polarization to the M1‑type through the connexin 43/NF‑κB pathway.
Molecular medicine reports
Wu L,Chen K,Xiao J,Xin J,Zhang L,Li X,Li L,Si J,Wang L,Ma K
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity.
Journal for immunotherapy of cancer
Efimova I,Catanzaro E,Van der Meeren L,Turubanova VD,Hammad H,Mishchenko TA,Vedunova MV,Fimognari C,Bachert C,Coppieters F,Lefever S,Skirtach AG,Krysko O,Krysko DV
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Intravenous injection of the oncolytic virus M1 awakens antitumor T cells and overcomes resistance to checkpoint blockade.
Cell death & disease
Liu Y,Cai J,Liu W,Lin Y,Guo L,Liu X,Qin Z,Xu C,Zhang Y,Su X,Deng K,Yan G,Liang J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sat Dec 12 00:00:00 EST 2020
MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization.
International journal of biological sciences
Zhu X,Liu H,Zhang Z,Wei R,Zhou X,Wang Z,Zhao L,Guo Q,Zhang Y,Chu C,Wang L,Li X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Fri Nov 12 00:00:00 EST 2021
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
Nature communications
Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Aug 27 00:00:00 EDT 2020
Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy.
Biomedicines
Ebelt ND,Zuniga E,Marzagalli M,Zamloot V,Blazar BR,Salgia R,Manuel ER
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Mesenchymal Stromal Cell-Derived Extracellular Vesicles Reduce Neuroinflammation, Promote Neural Cell Proliferation and Improve Oligodendrocyte Maturation in Neonatal Hypoxic-Ischemic Brain Injury.
Frontiers in cellular neuroscience
Kaminski N,Köster C,Mouloud Y,Börger V,Felderhoff-Müser U,Bendix I,Giebel B,Herz J
14-0862 was used in Immunohistochemistry to investigate the impact of mesenchymal stem/stromal cells-extracellular vesicless on neonatal hypoxia-ischemia-induced brain injury.
Tue Dec 29 00:00:00 EST 2020
A Novel Reporter Gene Assay for Pyrogen Detection.
Japanese journal of infectious diseases
He Q,Yu C,Wang L,Ni Y,Zhang H,Du Y,Gao H,Wang J
14-0862-82 was used in Flow cytometry/Cell sorting to suggest that the novel RGA has a wide pyrogen detection spectrum and is sufficiently sensitive, stable, and accurate for various applications.
Tue Mar 24 00:00:00 EDT 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Homotrimer cavin1 interacts with caveolin1 to facilitate tumor growth and activate microglia through extracellular vesicles in glioma.
Theranostics
Wang L,Yang C,Wang Q,Liu Q,Wang Y,Zhou J,Li Y,Tan Y,Kang C
14-0862 was used in Immunohistochemistry to study the role Cavin1-Caveolin1 interaction plays in regulating production and function of glioma-EVs.
Tue May 18 00:00:00 EDT 2021
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8+ T Cell Memory and Delayed Tumor Progression.
International journal of nanomedicine
Darling R,Senapati S,Christiansen J,Liu L,Ramer-Tait AE,Narasimhan B,Wannemuehler M
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Dec 07 00:00:00 EST 2020
Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer.
Molecular oncology
Zhou Z,Chen H,Xie R,Wang H,Li S,Xu Q,Xu N,Cheng Q,Qian Y,Huang R,Shao Z,Xiang M
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2019
Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells.
Stem cells and development
Fujii S,Yoshida S,Inagaki E,Hatou S,Tsubota K,Takahashi M,Shimmura S,Sugita S
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following Mycobacterium bovis Infection.
International journal of molecular sciences
Li Q,Liu C,Yue R,El-Ashram S,Wang J,He X,Zhao D,Zhou X,Xu L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Feb 19 00:00:00 EST 2019
Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation.
eLife
Bolger-Munro M,Choi K,Scurll JM,Abraham L,Chappell RS,Sheen D,Dang-Lawson M,Wu X,Priatel JJ,Coombs D,Hammer JA,Gold MR
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Jun 03 00:00:00 EDT 2019
Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction.
Frontiers in immunology
Fenninger F,Han J,Stanwood SR,Nohara LL,Arora H,Choi KB,Munro L,Pfeifer CG,Shanina I,Horwitz MS,Jefferies WA
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Oct 29 00:00:00 EDT 2020
Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins.
Nature communications
Serradell MC,Rupil LL,Martino RA,Prucca CG,Carranza PG,Saura A,Fernández EA,Gargantini PR,Tenaglia AH,Petiti JP,Tonelli RR,Reinoso-Vizcaino N,Echenique J,Berod L,Piaggio E,Bellier B,Sparwasser T,Klatzmann D,Luján HD
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Jan 21 00:00:00 EST 2019
Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer.
Journal of nanobiotechnology
Yuan SJ,Xu YH,Wang C,An HC,Xu HZ,Li K,Komatsu N,Zhao L,Chen X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Oct 17 00:00:00 EDT 2019
Effective chemoimmunotherapy by co-delivery of doxorubicin and immune adjuvants in biodegradable nanoparticles.
Theranostics
Da Silva CG,Camps MGM,Li TMWY,Zerrillo L,Löwik CW,Ossendorp F,Cruz LJ
14-0862-82 was used in Flow Cytometry to show that the multi-drug loaded nanoparticles mediated delivery of chemoimmunotherapy exhibited excellent therapeutic efficacy gain on two treatment resistant cancer models.
Fri Oct 23 00:00:00 EDT 2020
Semaphorin-3E Produced by Immature Dendritic Cells Regulates Activated Natural Killer Cells Migration.
Frontiers in immunology
Alamri A,Rahman R,Zhang M,Alamri A,Gounni AS,Kung SKP
14-0862 was used in Flow cytometry/Cell sorting to reveal a novel role of Sema-3E in limiting NK-cell migrations toward iDC in NK-DC crosstalk.
Thu Jul 11 00:00:00 EDT 2019
Cannabinoid 2 receptor attenuates inflammation during skin wound healing by inhibiting M1 macrophages rather than activating M2 macrophages.
Journal of inflammation (London, England)
Du Y,Ren P,Wang Q,Jiang SK,Zhang M,Li JY,Wang LL,Guan DW
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Immunohistochemistry
Wed Mar 30 00:00:00 EDT 2022
Ginsenoside Rg3 Mitigates Atherosclerosis Progression in Diabetic apoE-/- Mice by Skewing Macrophages to the M2 Phenotype.
Frontiers in pharmacology
Guo M,Xiao J,Sheng X,Zhang X,Tie Y,Wang L,Zhao L,Ji X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Targeting macrophage and microglia activation with colony stimulating factor 1 receptor inhibitor is an effective strategy to treat injury-triggered neuropathic pain.
Molecular pain
Lee S,Shi XQ,Fan A,West B,Zhang J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Oct 22 00:00:00 EDT 2018
T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells.
Nature communications
Kim HR,Mun Y,Lee KS,Park YJ,Park JS,Park JH,Jeon BN,Kim CH,Jun Y,Hyun YM,Kim M,Lee SM,Park CS,Im SH,Jun CD
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Fri Sep 07 00:00:00 EDT 2018
2-carba cyclic phosphatidic acid suppresses inflammation via regulation of microglial polarisation in the stab-wounded mouse cerebral cortex.
Scientific reports
Hashimoto K,Nakashima M,Hamano A,Gotoh M,Ikeshima-Kataoka H,Murakami-Murofushi K,Miyamoto Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Immunohistochemistry
Tue Jun 26 00:00:00 EDT 2018
C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America
Troegeler A,Mercier I,Cougoule C,Pietretti D,Colom A,Duval C,Vu Manh TP,Capilla F,Poincloux R,Pingris K,Nigou J,Rademann J,Dalod M,Verreck FA,Al Saati T,Lugo-Villarino G,Lepenies B,Hudrisier D,Neyrolles O
14-0862 was used in Flow cytometry/Cell sorting to reveal the modulatory role of the C-type lectin, DCIR, in tuberculosis-associated inflammation.
Tue Jan 24 00:00:00 EST 2017
TGF-β inhibitor Smad7 regulates dendritic cell-induced autoimmunity.
Proceedings of the National Academy of Sciences of the United States of America
Lukas D,Yogev N,Kel JM,Regen T,Mufazalov IA,Tang Y,Wanke F,Reizis B,Müller W,Kurschus FC,Prinz M,Kleiter I,Clausen BE,Waisman A
14-0862 was used in Flow cytometry/Cell sorting to demonstrate the role of Smad7 in the differentiation of dendritic cells in mice and their influence on the efficient function in immunity.
Tue Feb 21 00:00:00 EST 2017
FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells.
Frontiers in immunology
Pan YG,Yu YL,Lin CC,Lanier LL,Chu CL
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages.
Endocrinology
Li C,Ying W,Huang Z,Brehm T,Morin A,Vella AT,Zhou B
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Calreticulin is an effective immunologic adjuvant to tumor-associated antigens.
Experimental and therapeutic medicine
Wang J,Gao ZP,Qin S,Liu CB,Zou LL
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Oncoimmunology
Shen Y,Guo D,Weng L,Wang S,Ma Z,Yang Y,Wang P,Wang J,Cai Z
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Blocking CTLA-4 while priming with a whole cell vaccine reshapes the oligoclonal T cell infiltrate and eradicates tumors in an orthotopic glioma model.
Oncoimmunology
Field CS,Hunn MK,Ferguson PM,Ruedl C,Ancelet LR,Hermans IF
14-0862 was used in Flow cytometry/Cell sorting to study the effect of the checkpoint blockade on the efficacy of responses induced with a whole tumour-cell vaccine.
Tue Jan 12 00:00:00 EST 2021
T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels.
Journal of immunology (Baltimore, Md. : 1950)
Rota G,Ludigs K,Siegert S,Tardivel A,Morgado L,Reith W,De Gassart A,Guarda G
14-0862 was used in Flow cytometry/Cell sorting to show that Nlrc5 deficiency is not sufficient to hinder T cell activation, highlighting the robustness of the T cell priming process by activated dendritic cells.
Fri Apr 01 00:00:00 EDT 2016
Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS.
Human vaccines & immunotherapeutics
Xu X,Gao Y,Zhai Z,Zhang S,Shan F,Feng J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NFκB Pathway Suppression.
Journal of diabetes research
Zhou Z,Tang Y,Jin X,Chen C,Lu Y,Liu L,Shen C
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Jun 06 00:00:00 EDT 2017
CD80 and CD86 knockdown in dendritic cells regulates Th1/Th2 cytokine production in asthmatic mice.
Experimental and therapeutic medicine
Li JG,DU YM,Yan ZD,Yan J,Zhuansun YX,Chen R,Zhang W,Feng SL,Ran PX
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury.
Frontiers in cellular neuroscience
Hellström Erkenstam N,Smith PL,Fleiss B,Nair S,Svedin P,Wang W,Boström M,Gressens P,Hagberg H,Brown KL,Sävman K,Mallard C
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Immunofluorescence
Sat Jan 29 00:00:00 EST 2022
Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury.
Frontiers in cellular neuroscience
Hellström Erkenstam N,Smith PL,Fleiss B,Nair S,Svedin P,Wang W,Boström M,Gressens P,Hagberg H,Brown KL,Sävman K,Mallard C
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Immunofluorescence
Sat Jan 29 00:00:00 EST 2022
Cholera Toxin Promotes Th17 Cell Differentiation by Modulating Expression of Polarizing Cytokines and the Antigen-Presenting Potential of Dendritic Cells.
PloS one
Kang JO,Lee JB,Chang J
14-0862 was used in Flow cytometry/Cell sorting to determine how cholera toxin skews the differentiation of CD4 T cells to form IL-17-producing Th17 cells.
Tue Aug 08 00:00:00 EDT 2017
D-Alanylation of Teichoic Acids and Loss of Poly-N-Acetyl Glucosamine in Staphylococcus aureus during Exponential Growth Phase Enhance IL-12 Production in Murine Dendritic Cells.
PloS one
Lund LD,Ingmer H,Frøkiær H
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Jul 14 00:00:00 EDT 2016
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Nature
Carmi Y,Spitzer MH,Linde IL,Burt BM,Prestwood TR,Perlman N,Davidson MG,Kenkel JA,Segal E,Pusapati GV,Bhattacharya N,Engleman EG
14-0862 was used in Flow cytometry/Cell sorting to find that allogeneic tumour rejection is initiated in mice by naturally occurring tumour-binding IgG antibodies.
Thu May 07 00:00:00 EDT 2015
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease.
Blood
Flynn R,Allen JL,Luznik L,MacDonald KP,Paz K,Alexander KA,Vulic A,Du J,Panoskaltsis-Mortari A,Taylor PA,Poe JC,Serody JS,Murphy WJ,Hill GR,Maillard I,Koreth J,Cutler CS,Soiffer RJ,Antin JH,Ritz J,Chao NJ,Clynes RA,Sarantopoulos S,Blazar BR
14-0862 was used in Flow cytometry/Cell sorting to further evaluate the role of the spleen tyrosine kinase in graft-versus-host disease in multiple murine models and human peripheral blood cells.
Thu Jun 25 00:00:00 EDT 2015
Towards programming immune tolerance through geometric manipulation of phosphatidylserine.
Biomaterials
Roberts RA,Eitas TK,Byrne JD,Johnson BM,Short PJ,McKinnon KP,Reisdorf S,Luft JC,DeSimone JM,Ting JP
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Curing mice with large tumors by locally delivering combinations of immunomodulatory antibodies.
Clinical cancer research : an official journal of the American Association for Cancer Research
Dai M,Yip YY,Hellstrom I,Hellstrom KE
14086282 was used in flow cytometry to test the efficacy of combining different monoclonal antibodies to treat cancer
Sun Mar 01 00:00:00 EST 2015
β-catenin promotes regulatory T-cell responses in tumors by inducing vitamin A metabolism in dendritic cells.
Cancer research
Hong Y,Manoharan I,Suryawanshi A,Majumdar T,Angus-Hill ML,Koni PA,Manicassamy B,Mellor AL,Munn DH,Manicassamy S
14-0862 was used in Flow cytometry/Cell sorting to show that dendritic cells in the tumour microenvironment acquire the ability to metabolise vitamin A to produce retinoic acid, driving immune tolerance.
Sun Feb 15 00:00:00 EST 2015
The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection.
PLoS pathogens
Dalton JE,Glover AC,Hoodless L,Lim EK,Beattie L,Kirby A,Kaye PM
14-0862 was used in Flow cytometry/Cell sorting to investigate how Ntrk2 plays a role in the pathologic remodeling of the spleen that accompanies chronic infection.
Sun Feb 01 00:00:00 EST 2015
Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Lobo PI,Schlegel KH,Bajwa A,Huang L,Kurmaeva E,Wang B,Ye H,Tedder TF,Kinsey GR,Okusa MD
14-0862 was used in Flow cytometry/Cell sorting to investigate how natural IgM anti-leukocyte Abs can switch BMDC to a regulatory phenotype despite the presence of LPS that ordinarily induces BMDC maturation.
Tue Dec 01 00:00:00 EST 2015
Loss of MyD88 alters neuroinflammatory response and attenuates early Purkinje cell loss in a spinocerebellar ataxia type 6 mouse model.
Human molecular genetics
Aikawa T,Mogushi K,Iijima-Tsutsui K,Ishikawa K,Sakurai M,Tanaka H,Mizusawa H,Watase K
14-0862 was used in Immunohistochemistry on paraffin embedded tissues to suggest that early neuroinflammatory response may play an important role in the pathogenesis of SCA6.
Tue Sep 01 00:00:00 EDT 2015
Toll-Like Receptor 4 Is an Essential Upstream Regulator of On-Time Parturition and Perinatal Viability in Mice.
Endocrinology
Wahid HH,Dorian CL,Chin PY,Hutchinson MR,Rice KC,Olson DM,Moldenhauer LM,Robertson SA
14-0862 was used in Flow cytometry/Cell sorting to describe TLR4-mediated regulation of the inflammatory response acting to drive uterine activation and control the timing of labour.
Thu Oct 01 00:00:00 EDT 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Injectable cryogel-based whole-cell cancer vaccines.
Nature communications
Bencherif SA,Warren Sands R,Ali OA,Li WA,Lewin SA,Braschler TM,Shih TY,Verbeke CS,Bhatta D,Dranoff G,Mooney DJ
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Aug 12 00:00:00 EDT 2015
Deficient Natural Killer Dendritic Cell Responses Underlay the Induction of Theiler's Virus-Induced Autoimmunity.
mBio
Chastain EM,Getts DR,Miller SD
14-0862 was used in Flow cytometry/Cell sorting to determine that disease-susceptible SJL/J mice lacked a unique innate immune population, which plays a role in early CNS virus clearance.
Tue Aug 04 00:00:00 EDT 2015
Aquaporin-9-expressing neutrophils are required for the establishment of contact hypersensitivity.
Scientific reports
Moniaga CS,Watanabe S,Honda T,Nielsen S,Hara-Chikuma M
14-0862 was used in Flow cytometry/Cell sorting to suggest that AQP9 is required for the development of sensitisation during cutaneous acquired immune responses via regulating neutrophil function.
Thu Oct 22 00:00:00 EDT 2015
Depletion of B220+NK1.1+ cells enhances the rejection of established melanoma by tumor-specific CD4+ T cells.
Oncoimmunology
Wilson KA,Goding SR,Neely HR,Harris KM,Antony PA
14-0862 was used in Flow cytometry/Cell sorting to show that interferon-producing killer dendritic cells are an important inhibitor of the CD4(+) T cell response to melanoma.
Sat Aug 01 00:00:00 EDT 2015
Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity.
Blood
Lee-Chang C,Bodogai M,Moritoh K,Olkhanud PB,Chan AC,Croft M,Mattison JA,Holst PJ,Gress RE,Ferrucci L,Hakim F,Biragyn A
14-0862 was used in Flow cytometry/Cell sorting to propose that 4BL cells and the 4-1BBL signaling pathway are useful targets for improved effectiveness of natural antitumor defenses and therapeutic immune manipulations in the elderly.
Thu Aug 28 00:00:00 EDT 2014
Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response.
Journal of immunology (Baltimore, Md. : 1950)
Hu J,Oda SK,Shotts K,Donovan EE,Strauch P,Pujanauski LM,Victorino F,Al-Shami A,Fujiwara Y,Tigyi G,Oravecz T,Pelanda R,Torres RM
14-0862 was used in Flow cytometry/Cell sorting to reveal that alterations in lysophosphatidic acid levels likely influence adaptive humoural immunity.
Tue Jul 01 00:00:00 EDT 2014
B cell-specific loss of Lyn kinase leads to autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Lamagna C,Hu Y,DeFranco AL,Lowell CA
14-0862-82 was used in Flow Cytometry to demonstrate that B cell-intrinsic Lyn-dependent signalling pathways regulate B cell homeostasis and activation.
Sat Feb 01 00:00:00 EST 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.
Cellular immunology
Bakhru P,Sirisaengtaksin N,Soudani E,Mukherjee S,Khan A,Jagannath C
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
Lung dendritic cells undergo maturation and polarization towards a T helper type 2-stimulating phenotype in a mouse model of asthma: Role of nerve growth factor.
Experimental and therapeutic medicine
Qin Q,Wang Z,Pan P,Cao Z,Xia Q,Tan H,Hu C
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sat Nov 01 00:00:00 EDT 2014
Systemic sensitization with the protein allergen ovalbumin augments local sensitization in atopic dermatitis.
Journal of inflammation research
Yoo J,Manicone AM,McGuire JK,Wang Y,Parks WC
14-0862 was used in Immunofluorescence to reveal a mouse model of atopic dermatitis that reveals novel insights into the pathogenesis of this complex disease.
Thu Mar 27 00:00:00 EDT 2014
Identification of Toll-like receptor 9 as parapoxvirus ovis-sensing receptor in plasmacytoid dendritic cells.
PloS one
von Buttlar H,Siegemund S,Büttner M,Alber G
14-0862 was used in an ELISA assay to identify endosomal TLR9 as PPVO-sensing receptor in pDC.
Tue Nov 10 00:00:00 EST 2015
IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8⁺ T cell responses to influenza A virus.
Nature immunology
Pang IK,Ichinohe T,Iwasaki A
14-0862 was used in Flow cytometry/Cell sorting to demonstrate the critical role of the bystander cytokine IL-1 in priming CD8+ T cell responses to influenza A virus during infection.
Fri Mar 01 00:00:00 EST 2013
Direct and indirect antigen presentation lead to deletion of donor-specific T cells after in utero hematopoietic cell transplantation in mice.
Blood
Nijagal A,Derderian C,Le T,Jarvis E,Nguyen L,Tang Q,Mackenzie TC
14-0862 was used in Flow cytometry/Cell sorting to investigate the mechanisms of antigen presentation that induce a tolerant post-transplant immune response.
Thu May 30 00:00:00 EDT 2013
Klf10 inhibits IL-12p40 production in macrophage colony-stimulating factor-induced mouse bone marrow-derived macrophages.
European journal of immunology
Zhang W,Wang X,Xia X,Liu X,Suo S,Guo J,Li M,Cao W,Cai Z,Hui Z,Subramaniam M,Spelsberg TC,Wang J,Wang L
14-0862 was used in Flow cytometry/Cell sorting to identify Klf10 as a transcription factor that regulates the expression of IL-12p40 in bone marrow-derived macrophages.
Tue Jan 01 00:00:00 EST 2013
Histone deacetylase inhibitors suppress immune activation in primary mouse microglia.
Journal of neuroscience research
Kannan V,Brouwer N,Hanisch UK,Regen T,Eggen BJ,Boddeke HW
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2013
Phosphatidylserine exposure on the surface of Leishmania amazonensis amastigotes modulates in vivo infection and dendritic cell function.
Parasite immunology
Wanderley JLM,Thorpe PE,Barcinski MA,Soong L
14-0862 was used in Flow cytometry/Cell sorting to provide new information regarding the mechanism of immune suppression in Leishmania infection.
Wed Jul 17 00:00:00 EDT 2013
Neutralization of TSLP inhibits airway remodeling in a murine model of allergic asthma induced by chronic exposure to house dust mite.
PloS one
Chen ZG,Zhang TT,Li HT,Chen FH,Zou XL,Ji JZ,Chen H
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Tue Aug 20 00:00:00 EDT 2013
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.
Blood
Tewalt EF,Cohen JN,Rouhani SJ,Guidi CJ,Qiao H,Fahl SP,Conaway MR,Bender TP,Tung KS,Vella AT,Adler AJ,Chen L,Engelhard VH
14-0862 was used in Flow cytometry/Cell sorting to demonstrate that LECs mediate deletion only via programmed cell death-1 (PD-1) ligand 1.
Thu Dec 06 00:00:00 EST 2012
Adoptive transfer of immunomodulatory M2 macrophages prevents type 1 diabetes in NOD mice.
Diabetes
Parsa R,Andresen P,Gillett A,Mia S,Zhang XM,Mayans S,Holmberg D,Harris RA
14-0862 was used in Flow cytometry/Cell sorting to suggest that M2r macrophage therapy represents a novel intervention that stops ongoing autoimmune T1D and may have relevance in a clinical setting.
Thu Nov 01 00:00:00 EDT 2012
B7-CD28 costimulatory signals control the survival and proliferation of murine and human γδ T cells via IL-2 production.
Journal of immunology (Baltimore, Md. : 1950)
Ribot JC,Debarros A,Mancio-Silva L,Pamplona A,Silva-Santos B
14-0862 was used in Blocking experiments to show that CD28 signals are required for IL-2-mediated survival and proliferation of both CD27(+) and CD27(-) γδ T cell subsets.
Wed Aug 01 00:00:00 EDT 2012
Exposure to nicotine adversely affects the dendritic cell system and compromises host response to vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Nouri-Shirazi M,Guinet E
14-0862 was used in Flow cytometry/Cell sorting to investigate the causal relationship between nicotine-induced dendritic cell alterations and host response to vaccines.
Thu Mar 01 00:00:00 EST 2012
Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice.
PloS one
Kamphuis T,Meijerhof T,Stegmann T,Lederhofer J,Wilschut J,de Haan A
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Wed Sep 19 00:00:00 EDT 2012
CD81 is essential for the formation of membrane protrusions and regulates Rac1-activation in adhesion-dependent immune cell migration.
Blood
Quast T,Eppler F,Semmling V,Schild C,Homsi Y,Levy S,Lang T,Kurts C,Kolanus W
14-0862 was used in Flow cytometry/Cell sorting to investigate the role of CD81 in dendritic cells, showing that it is essential for the formation of membrane protrusions and regulates Rac1-activation in adhesion-dependent migration.
Thu Aug 18 00:00:00 EDT 2011
A critical role for granzymes in antigen cross-presentation through regulating phagocytosis of killed tumor cells.
Journal of immunology (Baltimore, Md. : 1950)
Hoves S,Sutton VR,Haynes NM,Hawkins ED,Fernández Ruiz D,Baschuk N,Sedelies KA,Schnurr M,Stagg J,Andrews DM,Villadangos JA,Trapani JA
14-0862 was used in Flow cytometry/Cell sorting to reveal a critical and previously unsuspected role for granzymes A and B in dictating immunogenicity by influencing the mode of tumour cell death.
Mon Aug 01 00:00:00 EDT 2011
Anti-CD180 (RP105) activates B cells to rapidly produce polyclonal Ig via a T cell and MyD88-independent pathway.
Journal of immunology (Baltimore, Md. : 1950)
Chaplin JW,Kasahara S,Clark EA,Ledbetter JA
14-0862-82 was used in Flow Cytometry to study the effect of injection of anti-CD180 mAb into mice on the production of immunoglobulins.
Sat Oct 15 00:00:00 EDT 2011
TCA cycle inactivation in Staphylococcus aureus alters nitric oxide production in RAW 264.7 cells.
Molecular and cellular biochemistry
Massilamany C,Gangaplara A,Gardner DJ,Musser JM,Steffen D,Somerville GA,Reddy J
14-0862 was used in Flow cytometry/Cell sorting to study the mechanisms by which Staphylococci can evade innate immune responses and enhance their ability to survive in infected hosts.
Thu Sep 01 00:00:00 EDT 2011
Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.
The Journal of experimental medicine
Swanson CL,Wilson TJ,Strauch P,Colonna M,Pelanda R,Torres RM
14-0862 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which toll-like receptor ligands influence T cell-independent type 2 antibody responses.
Mon Jul 05 00:00:00 EDT 2010
Potent anti-tumor responses to immunization with dendritic cells loaded with tumor tissue and an NKT cell ligand.
Immunology and cell biology
Petersen TR,Sika-Paotonu D,Knight DA,Dickgreber N,Farrand KJ,Ronchese F,Hermans IF
14-0862 was used in Flow cytometry/Cell sorting to investigate the impact of eliciting T-cell help from activated iNKT cells using alpha-galactosylceramide, showing potent anti-tumour response.
Thu Jul 01 00:00:00 EDT 2010
Rhipicephalus microplus salivary gland molecules induce differential CD86 expression in murine macrophages.
Parasites & vectors
Brake DK,Wikel SK,Tidwell JP,Pérez de León AA
14-0862 was used in Flow cytometry/Cell sorting to show that CD86 up-regulation is at least partially dependent on the ERK1/2 pathway and may serve to promote Th2 polarization of the immune response.
Fri Nov 05 00:00:00 EDT 2010
Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury.
The Journal of clinical investigation
Heymann F,Meyer-Schwesinger C,Hamilton-Williams EE,Hammerich L,Panzer U,Kaden S,Quaggin SE,Floege J,Gröne HJ,Kurts C
14-0862 was used in Flow cytometry/Cell sorting to investigate the role of several immune cell types within tubulointerstitial mononuclear cell infiltrates in the progression of kidney disease.
Fri May 01 00:00:00 EDT 2009
Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Huggins A,Paschalidis N,Flower RJ,Perretti M,D'Acquisto F
14-0862 was used in Flow cytometry/Cell sorting to suggest that the inhibition of Anx-A1 expression in dendritic cells may be useful to modulate the adaptive immune response in pathogen-induced immune diseases.
Wed Apr 01 00:00:00 EDT 2009
Langerin+ CD8alpha+ dendritic cells are critical for cross-priming and IL-12 production in response to systemic antigens.
Journal of immunology (Baltimore, Md. : 1950)
Farrand KJ,Dickgreber N,Stoitzner P,Ronchese F,Petersen TR,Hermans IF
14-0862 was used in Flow cytometry/Cell sorting to investigate the role of langerin(+)CD8alpha(+) dendritic cells in priming T cells, showing that they are critical for cross-priming and IL-12 production in response to systemic antigens.
Tue Dec 15 00:00:00 EST 2009
Adapter-mediated substrate selection for endoplasmic reticulum-associated degradation.
The Journal of biological chemistry
Corcoran K,Wang X,Lybarger L
14-0862 was used in Immunoprecipitation to demonstrate that heterologous substrates could be ubiquitinated by mK3 if recruited by ER accessory molecules to the ligase domain of mK3.
Fri Jun 26 00:00:00 EDT 2009
Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.
Nature immunology
Lee SW,Park Y,So T,Kwon BS,Cheroutre H,Mittler RS,Croft M
Published figure using CD86 (B7-2) monoclonal antibody (Product # 14-0862-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2008
CD40 and CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis.
American journal of respiratory and critical care medicine
Nolan A,Weiden M,Kelly A,Hoshino Y,Hoshino S,Mehta N,Gold JA
14-0862 was used in Blocking experiments to study CD40 and CD80/86 action in the regulation of inflammation and mortality in polymicrobial sepsis.
Fri Feb 01 00:00:00 EST 2008
Regulatory role of B cells in a murine model of allergic airway disease.
Journal of immunology (Baltimore, Md. : 1950)
Singh A,Carson WF,Secor ER,Guernsey LA,Flavell RA,Clark RB,Thrall RS,Schramm CM
14-0862 was used in Flow cytometry/Cell sorting to investigate the role of B cells in the resolution of allergic airway disease and induction of local inhalational tolerance.
Sun Jun 01 00:00:00 EDT 2008
17beta-Estradiol's salutary effects on splenic dendritic cell functions following trauma-hemorrhage are mediated via estrogen receptor-alpha.
Molecular immunology
Kawasaki T,Choudhry MA,Suzuki T,Schwacha MG,Bland KI,Chaudry IH
14-0862 was used in Flow cytometry/Cell sorting to investigate the effect of 17beta-estradiol on splenic dendritic cell function, showing that beneficial effects occur via estrogen receptor-alpha.
Tue Jan 01 00:00:00 EST 2008
Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity.
Molecular and cellular biology
Tenno M,Ohtsubo K,Hagen FK,Ditto D,Zarbock A,Schaerli P,von Andrian UH,Ley K,Le D,Tabak LA,Marth JD
14-0862 was used in Flow cytometry/Cell sorting to find that ppGalNAcT-1 plays key roles in cell and glycoprotein selective functions that modulate the haematopoietic system.
Sat Dec 01 00:00:00 EST 2007
-Flow-20170216130641.jpg?time=20220826 "CD86 (B7-2) Antibody in Flow Cytometry (Flow)")
-Flow-20170216130641.jpg?time=20220826)
-Flow-20170216130641.jpg?time=20220826?time=20220826 "CD86 (B7-2) Antibody (14-0862-82) in Flow")
